DE602005022619D1 - Verfahren zur herstellung von valsartan - Google Patents

Verfahren zur herstellung von valsartan

Info

Publication number
DE602005022619D1
DE602005022619D1 DE602005022619T DE602005022619T DE602005022619D1 DE 602005022619 D1 DE602005022619 D1 DE 602005022619D1 DE 602005022619 T DE602005022619 T DE 602005022619T DE 602005022619 T DE602005022619 T DE 602005022619T DE 602005022619 D1 DE602005022619 D1 DE 602005022619D1
Authority
DE
Germany
Prior art keywords
formula
compound
salt
valsartan
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005022619T
Other languages
English (en)
Inventor
Silvo Zupancic
Anica Pecavar
Rok Zupet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KRKA dd
Original Assignee
KRKA dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KRKA dd filed Critical KRKA dd
Publication of DE602005022619D1 publication Critical patent/DE602005022619D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE602005022619T 2004-11-30 2005-11-29 Verfahren zur herstellung von valsartan Active DE602005022619D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04028356A EP1661891A1 (de) 2004-11-30 2004-11-30 Verfahren zur Herstellung von Valsartan
PCT/EP2005/012736 WO2006058701A1 (en) 2004-11-30 2005-11-29 A process for the synthesis of valsartan

Publications (1)

Publication Number Publication Date
DE602005022619D1 true DE602005022619D1 (de) 2010-09-09

Family

ID=34927585

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005022619T Active DE602005022619D1 (de) 2004-11-30 2005-11-29 Verfahren zur herstellung von valsartan

Country Status (5)

Country Link
EP (2) EP1661891A1 (de)
AT (1) ATE475653T1 (de)
DE (1) DE602005022619D1 (de)
SI (1) SI1831186T1 (de)
WO (1) WO2006058701A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008035364A2 (en) * 2006-06-23 2008-03-27 Usv Limited Process for the preparation of micronized valsartan
WO2008004110A2 (en) * 2006-07-03 2008-01-10 Aurobindo Pharma Limited Process for the preparation of the angiotensin ii antagonist valsartan
WO2008007391A2 (en) * 2006-07-10 2008-01-17 Manne Satyanarayana Reddy An improved process for the preparation of valsartan
CN100522953C (zh) * 2007-04-03 2009-08-05 浙江天宇药业有限公司 一种缬沙坦的新合成方法
AU2008247136B2 (en) * 2007-05-07 2012-12-13 Cipla Limited Process for preparing valsartan
JP2010526126A (ja) * 2007-05-07 2010-07-29 シプラ・リミテッド バルサルタンの製造方法
CN101481374B (zh) * 2008-01-09 2013-01-09 浙江华海药业股份有限公司 1-三苯甲基-5-(1，1｀-联苯基-2基)-1h-四唑类化合物脱去三苯甲基的方法
EP2260018A2 (de) 2008-04-07 2010-12-15 Hetero Research Foundation Verfahren zur herstellung eines valsartan-zwischenprodukts
JP2010077077A (ja) * 2008-09-26 2010-04-08 Tokuyama Corp Ｎ−ペンタノイル−ｎ−［２’−（１ｈ−テトラゾール−５−イル）ビフェニル−４−イルメチル］−ｌ−バリンの製造方法
WO2012002189A1 (ja) * 2010-06-30 2012-01-05 株式会社トクヤマ バルサルタンの製造方法
WO2013072924A1 (en) * 2011-09-27 2013-05-23 Alkem Laboratories Ltd. An improved process for the preparation of angiotensin ii antagonists and intermediates thereof.
CN102617498B (zh) * 2012-03-16 2013-06-12 张家港市华昌药业有限公司 一种缬沙坦的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997030036A1 (en) * 1996-02-15 1997-08-21 Novartis Ag Aryl derivatives
AU2003223637A1 (en) * 2002-04-15 2003-11-03 Dr. Reddy's Laboratories Limited Novel crystalline forms of (s)-n-(1-carboxy-2-methyl-prop-1-yl) -n-pentanoyl-n- (2'-(1h-tetrazol-5-yl-)- biphenyl-4-yl methyl) amine (valsartan)
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
ATE393764T1 (de) * 2003-03-17 2008-05-15 Teva Pharma Polymorphe formen von valsartan
EP1556363A2 (de) * 2003-04-21 2005-07-27 Teva Pharmaceutical Industries Limited Verfahren zur herstellung von valsartan und zwischenprodukte davon
WO2004094392A1 (en) * 2003-04-21 2004-11-04 Teva Pharmaceutical Industries Ltd. Process for the preparation of valsartan
CZ298685B6 (cs) * 2003-05-15 2007-12-19 Zentiva, A.S. Zpusob výroby N-(1-oxopentyl)-N-[[2´-(1H-tetrazol-5-yl)[1,1´-bifenyl]-4-yl]methyl]-L-valinu (valsartanu)
GB0316546D0 (en) * 2003-07-15 2003-08-20 Novartis Ag Process for the manufacture of organic compounds
PL1658281T3 (pl) * 2003-08-27 2010-12-31 Zentiva Ks Sposób usuwania trifenylometanowej grupy zabezpieczającej

Also Published As

Publication number Publication date
SI1831186T1 (sl) 2010-10-29
ATE475653T1 (de) 2010-08-15
EP1661891A1 (de) 2006-05-31
EP1831186A1 (de) 2007-09-12
WO2006058701A1 (en) 2006-06-08
EP1831186B1 (de) 2010-07-28

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