DK1155019T3 - Substituerede porphyriner og deres terapeutiske anvendelse - Google Patents
Substituerede porphyriner og deres terapeutiske anvendelseInfo
- Publication number
- DK1155019T3 DK1155019T3 DK00905776T DK00905776T DK1155019T3 DK 1155019 T3 DK1155019 T3 DK 1155019T3 DK 00905776 T DK00905776 T DK 00905776T DK 00905776 T DK00905776 T DK 00905776T DK 1155019 T3 DK1155019 T3 DK 1155019T3
- Authority
- DK
- Denmark
- Prior art keywords
- therapeutic use
- substituted porphyrins
- oxidants
- relates
- processes
- Prior art date
Links
- 150000004032 porphyrins Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000007800 oxidant agent Substances 0.000 abstract 2
- 208000037273 Pathologic Processes Diseases 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000009054 pathological process Effects 0.000 abstract 1
- 230000035790 physiological processes and functions Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B47/00—Porphines; Azaporphines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11701099P | 1999-01-25 | 1999-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1155019T3 true DK1155019T3 (da) | 2006-04-18 |
Family
ID=22370524
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00905776T DK1155019T3 (da) | 1999-01-25 | 2000-01-25 | Substituerede porphyriner og deres terapeutiske anvendelse |
| DK05014279.3T DK1616869T3 (da) | 1999-01-25 | 2000-01-25 | Substituerede porphyriner og deres terapeutiske anvendelse |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05014279.3T DK1616869T3 (da) | 1999-01-25 | 2000-01-25 | Substituerede porphyriner og deres terapeutiske anvendelse |
Country Status (17)
| Country | Link |
|---|---|
| US (7) | US6544975B1 (enExample) |
| EP (3) | EP1616869B1 (enExample) |
| JP (1) | JP4501128B2 (enExample) |
| KR (1) | KR100753184B1 (enExample) |
| CN (1) | CN1156478C (enExample) |
| AT (2) | ATE552260T1 (enExample) |
| AU (1) | AU779283B2 (enExample) |
| BR (1) | BR0007720B1 (enExample) |
| CA (1) | CA2359116C (enExample) |
| DE (1) | DE60024588T2 (enExample) |
| DK (2) | DK1155019T3 (enExample) |
| ES (2) | ES2254142T3 (enExample) |
| IL (3) | IL144503A0 (enExample) |
| MX (1) | MXPA01007451A (enExample) |
| NZ (1) | NZ513164A (enExample) |
| WO (1) | WO2000043395A1 (enExample) |
| ZA (1) | ZA200106107B (enExample) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| US5747026A (en) * | 1993-10-15 | 1998-05-05 | University Of Alabama At Birmingham Research Foundation | Antioxidants |
| EP1045851B1 (en) | 1997-11-03 | 2003-04-23 | Duke University | Substituted porphyrins |
| CA2329751C (en) | 1998-04-24 | 2010-10-12 | Duke University | Substituted porphyrins |
| EP1616869B1 (en) | 1999-01-25 | 2012-04-04 | National Jewish Health | Substituted porphyrins and their therapeutic use |
| FR2806911B1 (fr) * | 2000-03-28 | 2003-01-10 | Univ Rene Descartes | Utilisation de mimetiques de la sod dans le traitement d'insuffisances hepatocellulaires |
| US20030069281A1 (en) * | 2000-06-14 | 2003-04-10 | Irwin Fridovich | Tetrapyrroles |
| CA2436245C (en) | 2001-01-19 | 2013-04-23 | National Jewish Medical And Research Center | Medicament for protection in radiotherapy |
| PT1389617E (pt) * | 2001-04-27 | 2007-04-30 | Zenyaku Kogyo Kk | Composto heterocíclico e agente antitumoral contendo o mesmo como igrediente activo |
| WO2002098431A1 (en) * | 2001-06-01 | 2002-12-12 | National Jewish Medical And Research Center | Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance |
| US20030086916A1 (en) * | 2001-10-12 | 2003-05-08 | Goligorsky Michael S. | Use of peroxynitrite scavengers or peroxynitrite formation inhibitors that do not diminish nitric oxide synthesis or activity to reverse or prevent premature vascular senescence |
| EP1513537A4 (en) * | 2002-06-07 | 2006-09-06 | Univ Duke | Substituted porphyrins |
| US20040127479A1 (en) * | 2002-08-27 | 2004-07-01 | Merck Patent Gmbh | Peroxynitrite rearrangement catalysts |
| EP1581212A4 (en) * | 2002-12-06 | 2008-11-05 | Alcon Inc | SUPEROXIDE DISMUTASE IMITATIONS FOR THE TREATMENT OF EYE DISORDERS AND DISEASES |
| GB2397067B (en) * | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
| EP1452175A1 (en) * | 2003-02-28 | 2004-09-01 | Medesis Pharma S.A. | Manganese based organometallic complexes, pharmaceutical compositions and dietetic products |
| US20080161255A1 (en) * | 2003-05-29 | 2008-07-03 | Michael Brownlee | Use of Parp Inhibitors for Prevention and Treatment of Diabetic and Insulin Resistance Complications |
| US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
| US7699964B2 (en) | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
| WO2005077269A1 (en) | 2004-02-09 | 2005-08-25 | Duke University | Substituted porphyrins |
| US8165651B2 (en) | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
| EA010834B1 (ru) * | 2004-03-29 | 2008-12-30 | Инотек Фармасьютикалз Корпорейшн | Пиридилзамещённые порфириновые соединения и способы их применения |
| GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
| WO2006037050A2 (en) * | 2004-09-24 | 2006-04-06 | Metaphore Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| GB0424294D0 (en) * | 2004-11-03 | 2004-12-01 | Elam T Ltd | Buffer layer |
| US7582751B2 (en) * | 2005-07-29 | 2009-09-01 | North Carolina State University | Methods and intermediates for the synthesis of porphyrins |
| US7501508B2 (en) * | 2005-07-29 | 2009-03-10 | North Caroline State University | Methods and intermediates for the synthesis of porphyrins |
| US7885698B2 (en) * | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
| WO2008070579A2 (en) * | 2006-12-01 | 2008-06-12 | Loma Linda University Medical Center | Inhibition of brain enzymes involved in cerebral amyloid angiopathy and macular degeneration |
| US20080289053A1 (en) * | 2007-05-15 | 2008-11-20 | The Regents Of The University Of California | Methods and systems for identifying modulators of longevity |
| WO2009004339A2 (en) * | 2007-07-03 | 2009-01-08 | Imperial Innovations Limited | Compositions and methods relating to manipulation of the myeloid immune compartment during respiratory infection |
| US8791099B2 (en) * | 2007-08-28 | 2014-07-29 | Technion Research And Development Foundation Ltd. | Transition metal complexes of corroles for preventing cardiovascular diseases or disorders |
| US8598150B1 (en) | 2008-04-02 | 2013-12-03 | Jonathan R. Brestoff | Composition and method for affecting obesity and related conditions |
| US8987245B2 (en) | 2008-04-02 | 2015-03-24 | Jonathan R. Brestoff Parker | Composition and method for affecting obesity and related conditions |
| ES2464728T3 (es) | 2008-05-23 | 2014-06-03 | National Jewish Health | Compuestos para su uso en el tratamiento de lesiones asociadas con la exposición a una especie química alquilante |
| US20120065181A1 (en) * | 2009-05-26 | 2012-03-15 | Warner David S | Method of providing neuroprotection using substituted porphyrins |
| WO2011028935A2 (en) * | 2009-09-02 | 2011-03-10 | The Regents Of The University Of Colorado | Methods of treating mitochondrial disorders using metalloporhyrins |
| HUE029083T2 (en) * | 2010-10-06 | 2017-02-28 | Aeolus Sciences Inc | Treatment of neurodegenerative diseases with porphyrin |
| WO2012105483A1 (ja) * | 2011-01-31 | 2012-08-09 | 国立大学法人宇都宮大学 | ポルフィリン型骨格を有する化合物の金属錯体の製造方法 |
| WO2013130150A2 (en) | 2011-12-02 | 2013-09-06 | The Regents Of The University Of Colorado, A Body Corporate | Metalloporphyrin neurological treatments |
| CN102775415B (zh) * | 2012-07-10 | 2014-10-22 | 西北大学 | 一种卟啉的合成方法 |
| US20140085895A1 (en) * | 2012-08-16 | 2014-03-27 | Thomas Frawley | LED Bracket Apparatus for High-Output LED Lighting Systems |
| EP3797798B1 (en) | 2013-03-14 | 2022-09-28 | Profusa, Inc. | Oxygen sensors |
| US20160113940A1 (en) | 2013-09-03 | 2016-04-28 | Biomimetix J.V., Llc | Methods of treating biofilms |
| CN105899514A (zh) * | 2013-11-22 | 2016-08-24 | 风神科学公司 | 卟啉化合物的合成和配制 |
| EP3089666B1 (en) | 2013-12-31 | 2020-08-19 | Abbott Diabetes Care Inc. | Self-powered analyte sensor and devices using the same |
| US10064871B2 (en) | 2014-01-22 | 2018-09-04 | Biomimetix Jv, Llc | Methods of treating skin disorders |
| US10080759B2 (en) | 2014-01-22 | 2018-09-25 | Duke University | Methods of treating pruritus |
| AT516549B1 (de) * | 2014-11-20 | 2017-05-15 | Wenatex Forschung - Entw - Produktion Gmbh | Antimikrobielles Mittel zum biociden Ausrüsten von Polymeren |
| EP3365349B1 (en) | 2015-08-18 | 2022-06-15 | University of Pittsburgh- Of the Commonwealth System of Higher Education | Viologen-functionalized porphyrins for reducing biofouling on surfaces |
| KR20190098211A (ko) * | 2016-12-20 | 2019-08-21 | 듀크 유니버시티 | 치환 포르피린 약학적 화합물 및 조성물의 제조 방법 |
| WO2018119204A1 (en) * | 2016-12-21 | 2018-06-28 | Profusa, Inc. | Polymerizable near-ir dyes |
| WO2020006248A1 (en) | 2018-06-27 | 2020-01-02 | Soya Gamsey | Near-ir glucose sensors |
| CN110028514B (zh) * | 2019-05-30 | 2021-07-02 | 湖南科技大学 | 5,10,15,20-四芳基-2,3-咪唑稠合-21-碳叶绿素化合物及制备方法 |
| EP3983486A1 (en) | 2019-06-14 | 2022-04-20 | Universidade de Coimbra | Small cationic ortho-5,15-di-heteroaryl-porphyrins derivatives and their applications in photoinactivation of microorganisms |
| US12201649B2 (en) | 2021-11-12 | 2025-01-21 | Villanova University | Pharmaceutical composition comprising oxidizable biphenol and manganese porphyrin, and method of using the same |
| CN116284017B (zh) * | 2023-03-27 | 2024-03-22 | 中国科学院青岛生物能源与过程研究所 | 一种利用仿酶高效催化氧化制备酰胺化合物的方法 |
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