MX2019007301A - Metodos para elaborar composiciones y compuestos farmaceuticos de porfirina sustituida. - Google Patents

Metodos para elaborar composiciones y compuestos farmaceuticos de porfirina sustituida.

Info

Publication number
MX2019007301A
MX2019007301A MX2019007301A MX2019007301A MX2019007301A MX 2019007301 A MX2019007301 A MX 2019007301A MX 2019007301 A MX2019007301 A MX 2019007301A MX 2019007301 A MX2019007301 A MX 2019007301A MX 2019007301 A MX2019007301 A MX 2019007301A
Authority
MX
Mexico
Prior art keywords
compositions
methods
pharmaceutical compounds
making substituted
substituted porphyrin
Prior art date
Application number
MX2019007301A
Other languages
English (en)
Inventor
Batinic-Haberle Ines
Tovmasyan Artak
Rajic Dzolic Zrinka
Spasojevic Ivan
Allen Lee Christopher
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Publication of MX2019007301A publication Critical patent/MX2019007301A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B47/00—Formation or introduction of functional groups not provided for in groups C07B39/00 - C07B45/00

Abstract

La presente invencion se refiere a metodos e intermediarios utiles para elaborar porfirinas sustituidas, incluyendo Mn(III) orto N - butoxietilpiridilporfirina y composiciones que comprenden el mismo; en algunas modalidades, un metodo de la presente invencion provee una composicion que tiene un cierto porcentaje o rendimiento (por ejemplo, al menos 80%, 85%, 90% o 95% en peso) de un compuesto de la presente invencion.
MX2019007301A 2016-12-20 2017-12-19 Metodos para elaborar composiciones y compuestos farmaceuticos de porfirina sustituida. MX2019007301A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662436743P 2016-12-20 2016-12-20
PCT/US2017/067263 WO2018118891A1 (en) 2016-12-20 2017-12-19 Methods of making substituted porphyrin pharmaceutical compounds and compositions

Publications (1)

Publication Number Publication Date
MX2019007301A true MX2019007301A (es) 2019-10-30

Family

ID=62628012

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019007301A MX2019007301A (es) 2016-12-20 2017-12-19 Metodos para elaborar composiciones y compuestos farmaceuticos de porfirina sustituida.

Country Status (8)

Country Link
US (1) US20190330220A1 (es)
EP (1) EP3558902A4 (es)
JP (1) JP2020502280A (es)
KR (1) KR20190098211A (es)
CN (1) CN110291060A (es)
CA (1) CA3046357A1 (es)
MX (1) MX2019007301A (es)
WO (1) WO2018118891A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110621377A (zh) 2017-04-04 2019-12-27 贝奥密美体合资有限公司 治疗和/或预防与放射和/或化疗暴露有关的副作用的方法、组合物以及试剂盒
CN111417400B (zh) 2017-09-29 2022-12-02 杜克大学 氟取代的卟啉化合物、包含其的药物组合物及其制备和使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127356A (en) * 1993-10-15 2000-10-03 Duke University Oxidant scavengers
EP1155019B1 (en) * 1999-01-25 2005-12-07 National Jewish Medical and Research Center Substituted porphyrins and their therapeutic use
JP2006501163A (ja) * 2002-06-07 2006-01-12 デューク・ユニバーシティー 置換ポルフィリン
US7807825B2 (en) * 2004-02-09 2010-10-05 Duke University Substituted porphyrins
US20110275606A1 (en) * 2009-01-07 2011-11-10 Duke University Substituted porphyrins
CA2762474A1 (en) * 2009-05-26 2010-12-02 Duke University Method of providing neuroprotection using substituted porphyrins
WO2015112586A1 (en) * 2014-01-22 2015-07-30 Duke University Methods of treating pruritus

Also Published As

Publication number Publication date
US20190330220A1 (en) 2019-10-31
CA3046357A1 (en) 2018-06-28
EP3558902A4 (en) 2020-06-24
KR20190098211A (ko) 2019-08-21
JP2020502280A (ja) 2020-01-23
CN110291060A (zh) 2019-09-27
EP3558902A1 (en) 2019-10-30
WO2018118891A1 (en) 2018-06-28

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