CL2020001589A1 - Proceso para la preparación de derivados de quinolina. - Google Patents
Proceso para la preparación de derivados de quinolina.Info
- Publication number
- CL2020001589A1 CL2020001589A1 CL2020001589A CL2020001589A CL2020001589A1 CL 2020001589 A1 CL2020001589 A1 CL 2020001589A1 CL 2020001589 A CL2020001589 A CL 2020001589A CL 2020001589 A CL2020001589 A CL 2020001589A CL 2020001589 A1 CL2020001589 A1 CL 2020001589A1
- Authority
- CL
- Chile
- Prior art keywords
- preparation
- quinoline derivatives
- new process
- well
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/44—Palladium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Abstract
La presente invención se refiere a un nuevo proceso para preparar compuestos de quinolina de la fórmula general (II): (II), en la cual Q, A, R4, R3 y R3’ son como se definen en el presente, así como los compuestos intermedios de dicho nuevo proceso. (II), en la cual Q, A, R4, R3 y R3’ son como se definen en el presente, así como los compuestos intermedios de dicho nuevo proceso.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17207586 | 2017-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2020001589A1 true CL2020001589A1 (es) | 2020-11-20 |
Family
ID=60673654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2020001589A CL2020001589A1 (es) | 2017-12-15 | 2020-06-12 | Proceso para la preparación de derivados de quinolina. |
Country Status (18)
Country | Link |
---|---|
US (1) | US11505544B2 (es) |
EP (1) | EP3692037A1 (es) |
JP (1) | JP2021506774A (es) |
KR (1) | KR20200099548A (es) |
CN (1) | CN111448192B (es) |
AU (1) | AU2018382999B2 (es) |
BR (1) | BR112020011901A2 (es) |
CA (1) | CA3085675A1 (es) |
CL (1) | CL2020001589A1 (es) |
CO (1) | CO2020007222A2 (es) |
DO (1) | DOP2020000118A (es) |
IL (1) | IL275216A (es) |
MX (1) | MX2020006185A (es) |
PH (1) | PH12020550905A1 (es) |
SG (1) | SG11202004260YA (es) |
TW (1) | TWI809018B (es) |
UY (1) | UY38009A (es) |
WO (1) | WO2019115768A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CR20210477A (es) | 2019-03-19 | 2022-01-06 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelmínticos |
CA3179528A1 (en) * | 2020-04-09 | 2021-10-14 | Bayer Animal Health Gmbh | Substituted condensed azines as anthelmintic compounds |
CN116249704A (zh) | 2020-05-29 | 2023-06-09 | 勃林格殷格翰动物保健美国公司 | 驱虫用杂环化合物 |
EP4148052A1 (en) * | 2021-09-09 | 2023-03-15 | Bayer Animal Health GmbH | New quinoline derivatives |
US20230159543A1 (en) | 2021-11-01 | 2023-05-25 | Boehringer Ingelheim Vetmedica Gmbh | Anthelmintic pyrrolopyridazine compounds |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0101999A3 (en) * | 1997-12-22 | 2003-06-30 | Upjohn Co | 4-hydroxyquinoline-3-carboxamides and hydrazides use of them and pharmaceutical compositions containing them |
CA2395772C (en) | 1999-12-28 | 2010-09-28 | Eisai Co., Ltd. | Sulfonamide-containing heterocyclic compounds |
CN100356979C (zh) | 2000-02-03 | 2007-12-26 | 卫材R&D管理有限公司 | 整联蛋白表达抑制剂 |
JP2008214323A (ja) | 2007-03-08 | 2008-09-18 | Kyowa Hakko Kogyo Co Ltd | 皮膚疾患の治療及び/または予防剤 |
US9006257B2 (en) | 2012-02-09 | 2015-04-14 | Glenmark Pharmaceuticals S.A. | Bicyclic compounds as mPGES-1 inhibitors |
AR098475A1 (es) * | 2013-11-26 | 2016-06-01 | Bayer Cropscience Ag | Compuestos pesticidas y usos |
PE20170331A1 (es) * | 2014-03-24 | 2017-04-28 | Guangdong Zhongsheng Pharmaceutical Co Ltd | Derivados quinolina como inhibidores smo |
BR112018012469B1 (pt) | 2015-12-17 | 2020-11-24 | Astex Therapeutics Limited | compostos quinolina-3-carboxamidas como inibidores da h-pgds, composição farmacêutica compreendendo os ditos compostos e uso terapêutico dos mesmos. |
EP3538512B1 (en) * | 2016-11-11 | 2021-06-16 | Bayer Animal Health GmbH | New anthelmintic quinoline-3-carboxamide derivatives |
-
2018
- 2018-12-14 SG SG11202004260YA patent/SG11202004260YA/en unknown
- 2018-12-14 AU AU2018382999A patent/AU2018382999B2/en active Active
- 2018-12-14 US US16/772,680 patent/US11505544B2/en active Active
- 2018-12-14 WO PCT/EP2018/084964 patent/WO2019115768A1/en unknown
- 2018-12-14 EP EP18815237.5A patent/EP3692037A1/en active Pending
- 2018-12-14 JP JP2020531937A patent/JP2021506774A/ja active Pending
- 2018-12-14 CA CA3085675A patent/CA3085675A1/en active Pending
- 2018-12-14 KR KR1020207020010A patent/KR20200099548A/ko active Search and Examination
- 2018-12-14 TW TW107145129A patent/TWI809018B/zh active
- 2018-12-14 BR BR112020011901-6A patent/BR112020011901A2/pt active Search and Examination
- 2018-12-14 UY UY0001038009A patent/UY38009A/es not_active Application Discontinuation
- 2018-12-14 MX MX2020006185A patent/MX2020006185A/es unknown
- 2018-12-14 CN CN201880080813.2A patent/CN111448192B/zh active Active
-
2020
- 2020-06-08 IL IL275216A patent/IL275216A/en unknown
- 2020-06-12 CL CL2020001589A patent/CL2020001589A1/es unknown
- 2020-06-12 CO CONC2020/0007222A patent/CO2020007222A2/es unknown
- 2020-06-15 DO DO2020000118A patent/DOP2020000118A/es unknown
- 2020-06-15 PH PH12020550905A patent/PH12020550905A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20200099548A (ko) | 2020-08-24 |
TW201927773A (zh) | 2019-07-16 |
CN111448192A (zh) | 2020-07-24 |
RU2020123282A (ru) | 2022-01-17 |
US20200308153A1 (en) | 2020-10-01 |
PH12020550905A1 (en) | 2021-05-17 |
SG11202004260YA (en) | 2020-06-29 |
AU2018382999A1 (en) | 2020-05-28 |
BR112020011901A2 (pt) | 2020-11-24 |
IL275216A (en) | 2020-07-30 |
CA3085675A1 (en) | 2019-06-20 |
US11505544B2 (en) | 2022-11-22 |
WO2019115768A1 (en) | 2019-06-20 |
TWI809018B (zh) | 2023-07-21 |
DOP2020000118A (es) | 2020-08-31 |
CN111448192B (zh) | 2024-04-12 |
JP2021506774A (ja) | 2021-02-22 |
UY38009A (es) | 2019-07-31 |
AU2018382999B2 (en) | 2023-11-23 |
CO2020007222A2 (es) | 2020-11-20 |
EP3692037A1 (en) | 2020-08-12 |
MX2020006185A (es) | 2020-09-03 |
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