ATE201595T1 - Metallporphyrinzusammensetzungen - Google Patents
MetallporphyrinzusammensetzungenInfo
- Publication number
- ATE201595T1 ATE201595T1 AT93921333T AT93921333T ATE201595T1 AT E201595 T1 ATE201595 T1 AT E201595T1 AT 93921333 T AT93921333 T AT 93921333T AT 93921333 T AT93921333 T AT 93921333T AT E201595 T1 ATE201595 T1 AT E201595T1
- Authority
- AT
- Austria
- Prior art keywords
- well
- metalporphyrin
- compositions
- metal
- treating
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- VAJVGAQAYOAJQI-UHFFFAOYSA-N 3-[18-(2-carboxylatoethyl)-3,8,13,17-tetramethyl-22,23-dihydroporphyrin-21,24-diium-2-yl]propanoate Chemical compound N1C(C=C2C(C)=CC(N2)=CC=2C(=C(CCC(O)=O)C(=C3)N=2)C)=CC(C)=C1C=C1C(C)=C(CCC(O)=O)C3=N1 VAJVGAQAYOAJQI-UHFFFAOYSA-N 0.000 abstract 1
- 208000030507 AIDS Diseases 0.000 abstract 1
- 102000004580 Aspartic Acid Proteases Human genes 0.000 abstract 1
- 108010017640 Aspartic Acid Proteases Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- KCIDZIIHRGYJAE-YGFYJFDDSA-L dipotassium;[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate Chemical class [K+].[K+].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@H]1O KCIDZIIHRGYJAE-YGFYJFDDSA-L 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- -1 porphyrin compounds Chemical class 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94009592A | 1992-09-03 | 1992-09-03 | |
| PCT/US1993/008317 WO1994005285A1 (en) | 1992-09-03 | 1993-09-03 | Metallo porphyrin compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201595T1 true ATE201595T1 (de) | 2001-06-15 |
Family
ID=25474216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93921333T ATE201595T1 (de) | 1992-09-03 | 1993-09-03 | Metallporphyrinzusammensetzungen |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0658109B1 (de) |
| JP (1) | JPH08501103A (de) |
| AT (1) | ATE201595T1 (de) |
| AU (1) | AU4846193A (de) |
| DE (1) | DE69330275T2 (de) |
| ES (1) | ES2157221T3 (de) |
| WO (1) | WO1994005285A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0626178A1 (de) * | 1993-05-17 | 1994-11-30 | Ciba-Geigy Ag | Verwendung von Hemmstoffen von HIV-Aspartatproteasen zur Bekämpfung von Tumorerkrankungen |
| DE69425666T2 (de) * | 1993-10-01 | 2001-04-12 | The Regents Of The University Of California, Oakland | Borierte metalloporphyrine und diagnostische verfahren |
| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| DE19708461A1 (de) * | 1997-02-18 | 1998-08-27 | Meulen Volker Prof Dr Ter | Verwendung aminerg wirkender Substanzen zur Herstellung eines Arzneimittels für die Behandlung viraler Infektionen des zentralen Nervensystems |
| DE69813898T2 (de) | 1997-11-03 | 2004-03-11 | Duke University | Substituierte porphyrinen |
| DK1071474T3 (da) * | 1998-04-24 | 2006-04-10 | Univ Duke | Substituerede porphyriner |
| ATE312103T1 (de) | 1999-01-25 | 2005-12-15 | Nat Jewish Med & Res Center | Substituierte porphyrine und deren therapeutische verwendungen |
| EP1439842A4 (de) | 2001-06-01 | 2009-09-02 | Nat Jewish Med & Res Center | Oxidantienfänger zur behandlung von diabetes oder zur verwendung bei der transplantation oder induktion von immuntoleranz |
| WO2003103680A1 (en) | 2002-06-07 | 2003-12-18 | Duke University | Substituted porphyrins |
| CZ303046B6 (cs) * | 2005-01-14 | 2012-03-14 | Vysoká Škola Chemicko-Technologická | II. Inhibitory HIV proteasy |
| DK2300003T3 (da) | 2008-05-23 | 2014-05-26 | Nat Jewish Health | Forbindelser til anvendelse i behandling af skade forbundet med eksponering for en alkylerende art |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128319A (en) * | 1987-08-28 | 1992-07-07 | Board Of Regents, The University Of Texas System | Prophylaxis and therapy of acquired immunodeficiency syndrome |
| EP0337598A3 (de) * | 1988-02-26 | 1991-07-03 | Georgia State University Foundation, Inc. | Verwendung von Porphyrinen und Metalloporphyrinen zur Behandlung von durch HIV verursachten Krankheiten |
| US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
| US4959356A (en) * | 1989-05-26 | 1990-09-25 | The United States Of America As Represented By The United States Department Of Energy | Porphyrins for boron neutron capture therapy |
| EP0543902A4 (en) * | 1990-07-31 | 1993-10-27 | The Rockefeller University | Use of metalloporphyrins to potentiate aids therapy |
| US5149801A (en) * | 1990-11-21 | 1992-09-22 | The Regents Of The University Of California | Boronated porphyrin compounds |
-
1993
- 1993-09-03 AT AT93921333T patent/ATE201595T1/de not_active IP Right Cessation
- 1993-09-03 AU AU48461/93A patent/AU4846193A/en not_active Abandoned
- 1993-09-03 WO PCT/US1993/008317 patent/WO1994005285A1/en not_active Ceased
- 1993-09-03 EP EP93921333A patent/EP0658109B1/de not_active Expired - Lifetime
- 1993-09-03 DE DE69330275T patent/DE69330275T2/de not_active Expired - Fee Related
- 1993-09-03 ES ES93921333T patent/ES2157221T3/es not_active Expired - Lifetime
- 1993-09-03 JP JP6507464A patent/JPH08501103A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69330275D1 (de) | 2001-07-05 |
| EP0658109A1 (de) | 1995-06-21 |
| WO1994005285A1 (en) | 1994-03-17 |
| EP0658109B1 (de) | 2001-05-30 |
| JPH08501103A (ja) | 1996-02-06 |
| ES2157221T3 (es) | 2001-08-16 |
| AU4846193A (en) | 1994-03-29 |
| EP0658109A4 (de) | 1997-04-09 |
| DE69330275T2 (de) | 2001-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |