DK1071474T3 - Substituerede porphyriner - Google Patents

Substituerede porphyriner

Info

Publication number
DK1071474T3
DK1071474T3 DK99919995T DK99919995T DK1071474T3 DK 1071474 T3 DK1071474 T3 DK 1071474T3 DK 99919995 T DK99919995 T DK 99919995T DK 99919995 T DK99919995 T DK 99919995T DK 1071474 T3 DK1071474 T3 DK 1071474T3
Authority
DK
Denmark
Prior art keywords
substituted porphyrins
oxidants
compounds
relates
processes
Prior art date
Application number
DK99919995T
Other languages
English (en)
Inventor
James D Crapo
Brian Day
Polivina Jolicia F Gauuan
Anthony D Pechulis Jr
Michael P Trova
Original Assignee
Univ Duke
Aeolus Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke, Aeolus Sciences Inc filed Critical Univ Duke
Application granted granted Critical
Publication of DK1071474T3 publication Critical patent/DK1071474T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK99919995T 1998-04-24 1999-04-23 Substituerede porphyriner DK1071474T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8288198P 1998-04-24 1998-04-24

Publications (1)

Publication Number Publication Date
DK1071474T3 true DK1071474T3 (da) 2006-04-10

Family

ID=22174053

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99919995T DK1071474T3 (da) 1998-04-24 1999-04-23 Substituerede porphyriner

Country Status (10)

Country Link
US (1) US6479477B1 (da)
EP (1) EP1071474B1 (da)
JP (1) JP4648542B2 (da)
AT (1) ATE311206T1 (da)
AU (1) AU771259B2 (da)
CA (1) CA2329751C (da)
DE (1) DE69928655T2 (da)
DK (1) DK1071474T3 (da)
ES (1) ES2257858T3 (da)
WO (1) WO1999055388A1 (da)

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WO2000009111A2 (en) * 1998-08-11 2000-02-24 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Inhibitors of amyloid formation
US20030032634A1 (en) * 2001-06-01 2003-02-13 Piganelli Jon D. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
US6544975B1 (en) * 1999-01-25 2003-04-08 National Jewish Medical And Research Center Substituted porphyrins
US6403788B1 (en) 2000-07-11 2002-06-11 Eukarion, Inc. Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species
JP2003012547A (ja) * 2001-06-27 2003-01-15 Meiji Seika Kaisha Ltd インスリン依存性糖尿病の診断剤および治療剤
US20040132706A1 (en) * 2001-10-05 2004-07-08 Daniela Salvemini Composition comprising a catalyst for the dismutation of superoxide and use of the composition for preventing and treating hypotension
ATE394398T1 (de) * 2002-07-15 2008-05-15 Scinopharm Taiwan Ltd Verfahren zur herstellung von imidazo(1,2- a)pyridin-3-acetamiden
GB2397067B (en) 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
US7649091B2 (en) * 2003-06-06 2010-01-19 Eukarion, Inc. Orally bioavailable low molecular weight metalloporphyrins as antioxidants
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
EP1718201B1 (en) * 2004-02-09 2016-09-14 Duke University Substituted porphyrins
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
EP1740094A4 (en) 2004-03-29 2008-09-03 Inotek Pharmaceuticals Corp PYRIDYL-SUBSTITUTED PORPHYRIN COMPOUNDS AND METHODS OF USE THEREOF
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US20080289053A1 (en) * 2007-05-15 2008-11-20 The Regents Of The University Of California Methods and systems for identifying modulators of longevity
EP2244701B1 (en) * 2008-01-31 2012-05-09 Technion Research and Development Foundation, Ltd. Corroles for neuroprotection and neurorescue
JP5608644B2 (ja) 2008-05-23 2014-10-15 ナショナル ジューイッシュ ヘルス アルキル化種の被爆に関連する損傷の処置方法
RS54911B1 (sr) * 2010-10-06 2016-10-31 Aeolus Sciences Inc Lečenje neurodegenerativnih oboljenja porfirinom
MX2014006255A (es) 2011-12-02 2015-04-10 Univ Colorado Regents Tratamientos neurologiocos con metaloporfirina.
US10646595B2 (en) * 2013-02-12 2020-05-12 The Governing Council Of The University Of Toronto Porphyrin compounds and their use as MRI contrast agents
US20160113940A1 (en) 2013-09-03 2016-04-28 Biomimetix J.V., Llc Methods of treating biofilms
JP6571089B2 (ja) 2013-12-31 2019-09-04 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 電源内蔵式分析物センサ及びそれを使用するデバイス
US10064871B2 (en) 2014-01-22 2018-09-04 Biomimetix Jv, Llc Methods of treating skin disorders
US10080759B2 (en) 2014-01-22 2018-09-25 Duke University Methods of treating pruritus
KR101894575B1 (ko) * 2017-01-03 2018-09-04 주식회사 인트론바이오테크놀로지 돼지 피로부터 유래되지 않은 헴철을 제조할 수 있는 화학적 방법
EP4225759A1 (en) * 2020-10-05 2023-08-16 biolitec Unternehmensbeteiligungs II AG Tetrapyrrole-based compounds and their formulations for anti-microbial therapy

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US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
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US4746735A (en) 1986-11-21 1988-05-24 The Dow Chemical Company Regiospecific aryl nitration of meso-substituted tetraarylporphyrins
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US5227405A (en) 1987-03-31 1993-07-13 Duke University Superoxide dismutase mimic
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FR2632187B1 (fr) 1988-06-02 1990-09-14 Centre Nat Rech Scient Derives de metalloporphyrines, leur preparation, leur application en therapeutique et leur utilisation pour la preparation de molecules hybrides
US5171680A (en) 1988-06-14 1992-12-15 Chiron Corporation Superoxide dismutase analogs having novel binding properties
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US5217966A (en) 1990-09-13 1993-06-08 The Regents Of The University Of California Synthetic drug molecules that mimic metalloenzymes
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Also Published As

Publication number Publication date
CA2329751A1 (en) 1999-11-04
JP2002512989A (ja) 2002-05-08
EP1071474A1 (en) 2001-01-31
EP1071474A4 (en) 2002-10-24
WO1999055388A1 (en) 1999-11-04
AU3758899A (en) 1999-11-16
ATE311206T1 (de) 2005-12-15
JP4648542B2 (ja) 2011-03-09
ES2257858T3 (es) 2006-08-01
EP1071474B1 (en) 2005-11-30
CA2329751C (en) 2010-10-12
WO1999055388A9 (en) 2000-01-27
DE69928655T2 (de) 2006-08-24
AU771259B2 (en) 2004-03-18
US6479477B1 (en) 2002-11-12
DE69928655D1 (de) 2006-01-05

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