AU8947791A - Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions - Google Patents

Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions

Info

Publication number
AU8947791A
AU8947791A AU89477/91A AU8947791A AU8947791A AU 8947791 A AU8947791 A AU 8947791A AU 89477/91 A AU89477/91 A AU 89477/91A AU 8947791 A AU8947791 A AU 8947791A AU 8947791 A AU8947791 A AU 8947791A
Authority
AU
Australia
Prior art keywords
glycosaminoglycan
compositions
construction
design
fusion proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU89477/91A
Inventor
Maurice Boissinot
Cindy Fisher
John H Griffin
Robert A Hallewell
Leslie Kuhn
Guy T Mullenbach
Hans E Parge
John A Tainer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of AU8947791A publication Critical patent/AU8947791A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
AU89477/91A 1990-11-01 1991-11-01 Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions Abandoned AU8947791A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60853990A 1990-11-01 1990-11-01
US608539 1990-11-01
US60856990A 1990-11-02 1990-11-02
US608569 1990-11-02

Publications (1)

Publication Number Publication Date
AU8947791A true AU8947791A (en) 1992-05-26

Family

ID=27085796

Family Applications (1)

Application Number Title Priority Date Filing Date
AU89477/91A Abandoned AU8947791A (en) 1990-11-01 1991-11-01 Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions

Country Status (2)

Country Link
AU (1) AU8947791A (en)
WO (1) WO1992007935A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US5506133A (en) * 1994-04-11 1996-04-09 Human Genome Sciences, Inc. Superoxide dismutase-4
AU3758695A (en) * 1994-09-20 1996-04-09 Duke University Oxidoreductase activity of manganic porphyrins
US5866402A (en) * 1995-05-05 1999-02-02 Chiron Corporation Chimeric MCP and DAF proteins with cell surface localizing domain
AU1374599A (en) * 1997-10-31 1999-05-24 University Of Florida Materials and methods for preventing cellular injury in humans and animals
DE69813898T2 (en) 1997-11-03 2004-03-11 Duke University SUBSTITUTED PORPHYRINES
WO1999055388A1 (en) 1998-04-24 1999-11-04 Duke University Substituted porphyrins
CA2359116C (en) 1999-01-25 2009-03-17 National Jewish Medical And Research Center Substituted porphyrins
AU2002312194B8 (en) 2001-06-01 2008-05-15 Aeolus Sciences, Inc. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
AU2002322762B2 (en) * 2001-07-31 2008-10-16 Wayne State University Hybrid proteins with neuregulin heparin-binding domain for targeting to heparan sulfate proteoglycans
AU2003237500A1 (en) 2002-06-07 2003-12-22 Duke University Substituted porphyrins
AT412785B (en) * 2003-12-04 2005-07-25 Kungl Andreas J Dr GAG BINDING PROTEINS
BRPI0520563A2 (en) * 2005-09-21 2009-05-19 7Tm Pharma As selective y4 receptor agonists for therapeutic interventions
AU2005337101A1 (en) 2005-09-21 2007-04-12 7Tm Pharma A/S Y2 selective receptor agonists for therapeutic interventions
EP2300003B1 (en) 2008-05-23 2014-03-05 National Jewish Health Compounds for use in treating injury associated with exposure to an alkylating species
JP5799409B2 (en) * 2008-12-19 2015-10-28 国立大学法人 新潟大学 Heparin affinity erythropoietin
AU2020318955A1 (en) * 2019-07-23 2022-03-03 Csts Health Care Inc. Platelet-facilitated delivery of therapeutic compounds
CN114703154B (en) * 2022-03-30 2024-01-09 云南大学 Polypeptide, protein containing same and application

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013653A (en) * 1987-03-20 1991-05-07 Creative Biomolecules, Inc. Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
DE69027383T2 (en) * 1989-03-06 1996-11-14 Suntory Ltd NEW SUPEROXYD DISMUTASE

Also Published As

Publication number Publication date
WO1992007935A1 (en) 1992-05-14

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