DK402785D0 - Fremgangsmaade til fremstilling af et enzym - Google Patents

Fremgangsmaade til fremstilling af et enzym

Info

Publication number
DK402785D0
DK402785D0 DK402785A DK402785A DK402785D0 DK 402785 D0 DK402785 D0 DK 402785D0 DK 402785 A DK402785 A DK 402785A DK 402785 A DK402785 A DK 402785A DK 402785 D0 DK402785 D0 DK 402785D0
Authority
DK
Denmark
Prior art keywords
sod
recovering
growing
cell
superoxide dismutase
Prior art date
Application number
DK402785A
Other languages
English (en)
Inventor
Stefan Marklund
Thomas Edlund
Original Assignee
Syn Tek Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syn Tek Ab filed Critical Syn Tek Ab
Priority to DK402785A priority Critical patent/DK402785D0/da
Publication of DK402785D0 publication Critical patent/DK402785D0/da
Priority to HU864441A priority patent/HU215937B/hu
Priority to IE234286A priority patent/IE59078B1/en
Priority to EP86905243A priority patent/EP0236385B1/en
Priority to AT86905243T priority patent/ATE69466T1/de
Priority to AU63708/86A priority patent/AU598756B2/en
Priority to IL7992686A priority patent/IL79926A/en
Priority to KR1019870700381A priority patent/KR920008738B1/ko
Priority to PCT/DK1986/000098 priority patent/WO1987001387A1/en
Priority to JP61505070A priority patent/JP2643934B2/ja
Priority to CN86106774A priority patent/CN1030718C/zh
Priority to DE8686905243T priority patent/DE3682505D1/de
Priority to CA000517419A priority patent/CA1340329C/en
Priority to ZA871267A priority patent/ZA871267B/xx
Priority to FI871853A priority patent/FI100252B/fi
Priority to SU874202612A priority patent/SU1779263A3/ru
Priority to NO871816A priority patent/NO301132B1/no
Priority to DK224587A priority patent/DK224587A/da
Priority to US07/576,114 priority patent/US5130245A/en
Priority to US07/897,624 priority patent/US5248603A/en
Priority to US08/125,744 priority patent/US5472691A/en
Priority to US08/446,104 priority patent/US5788961A/en
Priority to JP8101552A priority patent/JP2688190B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
DK402785A 1985-09-03 1985-09-03 Fremgangsmaade til fremstilling af et enzym DK402785D0 (da)

Priority Applications (23)

Application Number Priority Date Filing Date Title
DK402785A DK402785D0 (da) 1985-09-03 1985-09-03 Fremgangsmaade til fremstilling af et enzym
IE234286A IE59078B1 (en) 1985-09-03 1986-09-02 A superoxide dismutase
CN86106774A CN1030718C (zh) 1985-09-03 1986-09-02 一种超氧化物歧化酶
DE8686905243T DE3682505D1 (de) 1985-09-03 1986-09-02 Superoxyddismutase.
EP86905243A EP0236385B1 (en) 1985-09-03 1986-09-02 A superoxide dismutase
AT86905243T ATE69466T1 (de) 1985-09-03 1986-09-02 Superoxyddismutase.
AU63708/86A AU598756B2 (en) 1985-09-03 1986-09-02 A superoxide dismutase
IL7992686A IL79926A (en) 1985-09-03 1986-09-02 Super-extracellular dismutase oxide of humans, DNA fragment Encoding it, a recombinant method to generate the same vectors and cells to use the same method, a method to receive
KR1019870700381A KR920008738B1 (ko) 1985-09-03 1986-09-02 초과산화물 부동변화효소의 제조방법
PCT/DK1986/000098 WO1987001387A1 (en) 1985-09-03 1986-09-02 A superoxide dismutase
JP61505070A JP2643934B2 (ja) 1985-09-03 1986-09-02 スーパーオキシドジスムターゼ
HU864441A HU215937B (hu) 1985-09-03 1986-09-02 Eljárás extracelluláris szuperoxid-diszmutáz, és hatóanyagként ezt tartalmazó gyógyászati készítmények előállítására
CA000517419A CA1340329C (en) 1985-09-03 1986-09-03 Superoxide dismutasee
ZA871267A ZA871267B (en) 1985-09-03 1987-02-20 A superoxide dismutase
FI871853A FI100252B (fi) 1985-09-03 1987-04-28 Menetelmä superoksididismutaasin valmistamiseksi ja sitä koodittava DN A-fragmentti, ilmentymisvektori ja solu
SU874202612A SU1779263A3 (ru) 1985-09-03 1987-04-30 Способ получения внеклеточной перекисной дисмутазы человека 2
NO871816A NO301132B1 (no) 1985-09-03 1987-04-30 Fremgangsmåte til fremstilling av superoksid dismutase
DK224587A DK224587A (da) 1985-09-03 1987-05-01 Ekstracellulaer superoxiddismutase (ec-sod), dna-fragment, der indkoder ec-sod, fremgangsmaade til fremstilling af ec-sod samt anvendelse af ec-sod
US07/576,114 US5130245A (en) 1985-09-03 1990-08-27 Superoxide dismutase
US07/897,624 US5248603A (en) 1985-09-03 1992-06-12 Superoxide dismutase
US08/125,744 US5472691A (en) 1985-09-03 1993-09-24 Superoxide dismutase
US08/446,104 US5788961A (en) 1985-09-03 1995-05-19 Superoxide dismutase
JP8101552A JP2688190B2 (ja) 1985-09-03 1996-04-23 Ｄｎａフラグメント

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK402785A DK402785D0 (da) 1985-09-03 1985-09-03 Fremgangsmaade til fremstilling af et enzym

Publications (1)

Publication Number Publication Date
DK402785D0 true DK402785D0 (da) 1985-09-03

Family

ID=8129425

Family Applications (2)

Application Number Title Priority Date Filing Date
DK402785A DK402785D0 (da) 1985-09-03 1985-09-03 Fremgangsmaade til fremstilling af et enzym
DK224587A DK224587A (da) 1985-09-03 1987-05-01 Ekstracellulaer superoxiddismutase (ec-sod), dna-fragment, der indkoder ec-sod, fremgangsmaade til fremstilling af ec-sod samt anvendelse af ec-sod

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK224587A DK224587A (da) 1985-09-03 1987-05-01 Ekstracellulaer superoxiddismutase (ec-sod), dna-fragment, der indkoder ec-sod, fremgangsmaade til fremstilling af ec-sod samt anvendelse af ec-sod

Country Status (18)

Country Link
US (1) US5130245A (da)
EP (1) EP0236385B1 (da)
JP (2) JP2643934B2 (da)
KR (1) KR920008738B1 (da)
CN (1) CN1030718C (da)
AT (1) ATE69466T1 (da)
AU (1) AU598756B2 (da)
CA (1) CA1340329C (da)
DE (1) DE3682505D1 (da)
DK (2) DK402785D0 (da)
FI (1) FI100252B (da)
HU (1) HU215937B (da)
IE (1) IE59078B1 (da)
IL (1) IL79926A (da)
NO (1) NO301132B1 (da)
SU (1) SU1779263A3 (da)
WO (1) WO1987001387A1 (da)
ZA (1) ZA871267B (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213628A3 (en) * 1985-09-03 1988-09-21 Yeda Research And Development Company, Ltd. Expression of superoxide dismutase in eukaryotic cells
US6610520B1 (en) * 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS63132820A (ja) * 1986-11-22 1988-06-04 Minoru Nakano 口腔用組成物
DE3854872D1 (de) * 1987-03-14 1996-02-22 Boehringer Ingelheim Int Humane Mangan-Superoxiddismutase (hMn-SOD)
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
ATE130196T1 (de) * 1987-03-27 1995-12-15 Bio Technology General Corp Menschliches mangansuperoxiddismutase und behandlungsverfahren.
DK310788A (da) * 1987-06-09 1988-12-10 Int Cardiovascular Med Inc Praeparat indeholdende superoxid-dismutase, dets fremstilling og anvendelse til behandling af global iskaemi
JPH01238537A (ja) * 1988-03-18 1989-09-22 Toyo Jozo Co Ltd 肝障害治療剤
JPH01246225A (ja) * 1988-03-28 1989-10-02 Toyo Jozo Co Ltd 膵炎治療剤
JPH0262829A (ja) * 1988-05-18 1990-03-02 Nippon Kayaku Co Ltd 虚血に基づく傷害の予防及び治療剤
DK455789D0 (da) * 1989-09-15 1989-09-15 Symbicom Ab Polypeptid
DE4038563A1 (de) * 1990-12-04 1992-06-11 Gruenenthal Gmbh Verwendung von superoxiddismutasen zur prophylaxe und/oder behandlung von organversagen bei risikopatienten mit polytrauma
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
EP0627486A1 (en) * 1993-06-04 1994-12-07 N.V. Innogenetics S.A. New extracellular superoxide dismutase, a process for preparing the same and compositions containing the same
DK75393D0 (da) * 1993-06-24 1993-06-24 Symbicom Ab Production of protein
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
DE4336641C2 (de) * 1993-10-22 1995-09-07 Deutsches Rheuma Forschungszen Verwendung von Superoxid-Dismutase (SOD) zur Behandlung retroviraler Erkrankungen
WO1996009053A1 (en) * 1994-09-20 1996-03-28 Duke University Oxidoreductase activity of manganic porphyrins
ATE205723T1 (de) * 1994-11-04 2001-10-15 Polymun Scient Immunbio Forsch Applikation von sod in liposomen
MY128323A (en) * 1996-09-30 2007-01-31 Otsuka Pharma Co Ltd Thiazole derivatives for inhibition of cytokine production and of cell adhesion
US6171856B1 (en) 1997-07-30 2001-01-09 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
WO1999006059A2 (en) * 1997-07-30 1999-02-11 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
IL135949A0 (en) 1997-11-03 2001-05-20 Univ Duke Substituted porphyrins
CA2329751C (en) 1998-04-24 2010-10-12 Duke University Substituted porphyrins
ATE312103T1 (de) 1999-01-25 2005-12-15 Nat Jewish Med & Res Center Substituierte porphyrine und deren therapeutische verwendungen
WO2002060383A2 (en) * 2001-01-19 2002-08-08 National Jewish Medical And Research Center Cancer therapy
FI20010898A0 (fi) * 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
JP2005508864A (ja) * 2001-06-01 2005-04-07 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー
AU2003224587A1 (en) * 2002-04-30 2003-11-17 Fit Biotech Oyj Plc Medical device
US7485721B2 (en) * 2002-06-07 2009-02-03 Duke University Substituted porphyrins
US7740839B2 (en) * 2003-10-31 2010-06-22 Tae-Yoon Kim EC SOD and cell transducing EC SOD and use thereof
CN100345973C (zh) * 2004-11-18 2007-10-31 中国农业大学 超氧化物歧化酶基因的表达方法及其专用载体
JP5608644B2 (ja) 2008-05-23 2014-10-15 ナショナル ジューイッシュ ヘルス アルキル化種の被爆に関連する損傷の処置方法
US20100098768A1 (en) * 2008-10-16 2010-04-22 Clarkson University Method of neuroprotection from oxidant injury using metal oxide nanoparticles
CN102660580A (zh) * 2012-05-18 2012-09-12 深圳市北科生物科技有限公司 Sod基因修饰间充质干细胞的构建方法及其应用
MX363474B (es) * 2013-03-15 2019-03-25 Baxter Int Inmovilizacion de un agente activo en un sustrato.
EP3003413B1 (en) 2013-06-07 2017-12-13 Baxter International Inc. Immobilization of an active agent on a substrate using compounds including trihydroxyphenyl groups
CN104342409B (zh) * 2014-06-17 2018-05-25 吉林金梓源生物科技股份有限公司 重组人参超氧化物歧化酶的制备方法
CN104342408B (zh) * 2014-06-18 2018-05-25 吉林金梓源生物科技股份有限公司 重组蛹虫草超氧化物歧化酶的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145950C (da) * 1979-05-17 1983-09-26 Forenede Bryggerier As Fremgangsmaade til isolering af cu,zn-superoxid-dismutase fra vandige oploesninger indeholdende dette enzym sammen med ledsagende proteiner
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
JPS5729285A (en) * 1980-07-30 1982-02-17 Takeda Chem Ind Ltd Superoxide dismutase and its preparation
JPS57155991A (en) * 1981-03-23 1982-09-27 Green Cross Corp:The Preparation of superoxide dismutase derived from human placenta
EP0091539B2 (en) * 1982-03-31 1996-11-27 Ajinomoto Co., Inc. Gene coding for interleukin-2 polypeptide, recombinant DNA carrying said gene, cell lines possessing the recombinant DNA,and method for producing interleukin-2 using said cells
IT1150598B (it) * 1982-12-14 1986-12-17 Ines Bianchi Procedimento per la purificazione della superossidodismutasi mediante cromatografia di affinita'
EP0138111B1 (en) * 1983-10-03 1991-11-21 Chiron Corporation Superoxide dismutase cloning and expression in microorganisms
JPS61111690A (ja) * 1984-11-06 1986-05-29 Ube Ind Ltd 組換えｄｎａおよびその用途
JPS61139390A (ja) * 1984-12-13 1986-06-26 Nippon Kayaku Co Ltd ひとｓｏｄをコ−ドする新規ｄｎａおよびそれを有する微生物

Also Published As

Publication number Publication date
WO1987001387A1 (en) 1987-03-12
AU6370886A (en) 1987-03-24
NO871816D0 (no) 1987-04-30
NO871816L (no) 1987-07-02
EP0236385B1 (en) 1991-11-13
JPH08317793A (ja) 1996-12-03
FI871853A (fi) 1987-04-28
ZA871267B (en) 1987-10-28
JPS63501473A (ja) 1988-06-09
ATE69466T1 (de) 1991-11-15
JP2688190B2 (ja) 1997-12-08
US5130245A (en) 1992-07-14
EP0236385A1 (en) 1987-09-16
KR920008738B1 (ko) 1992-10-08
NO301132B1 (no) 1997-09-15
IE59078B1 (en) 1994-01-12
FI871853A0 (fi) 1987-04-28
IL79926A0 (en) 1986-12-31
CN1030718C (zh) 1996-01-17
AU598756B2 (en) 1990-07-05
CN86106774A (zh) 1987-07-15
HUT46059A (en) 1988-09-28
FI100252B (fi) 1997-10-31
DK224587D0 (da) 1987-05-01
IE862342L (en) 1987-03-03
JP2643934B2 (ja) 1997-08-25
IL79926A (en) 1994-10-07
HU215937B (hu) 1999-03-29
CA1340329C (en) 1999-01-26
SU1779263A3 (ru) 1992-11-30
DE3682505D1 (de) 1991-12-19
DK224587A (da) 1987-05-01
KR880700066A (ko) 1988-02-15

Similar Documents

Publication Publication Date Title
DK402785D0 (da) Fremgangsmaade til fremstilling af et enzym
ES2056817T3 (es) Transformacion de trichoderma.
KR880701736A (ko) Il-6의 제조방법 및 용도
PH25120A (en) Replicable expression vehicle and process of preparation thereof
AU6329694A (en) Recombinant expression vectors and purification methods for thermus thermophilus DNA polymerase
FI885679A0 (fi) Samuttryckning i eukariotiska celler.
ES469328A1 (es) Procedimiento para el enriquecimiento de una nueva glucopre-teina.
JPS6420095A (en) Polypeptide having anti-blood coagulating action
EP0222591A3 (en) Method and nucleic acid for the preparation of lecithin: cholesterol acyltransferase
ES2111537T3 (es) Inhibidor de la ribonucleasa de placenta humana recombinante y metodo de produccion.
ATE136901T1 (de) Antigen gegen diabetes
ES8801959A1 (es) Un procedimiento para ensayos de sangre humana respecto de la presencia de anticuerpos frente al agente etiologico viral de sida