NO871816D0 - Superoksiddismutase og fremgangsmaate til dens fremstilling - Google Patents

Superoksiddismutase og fremgangsmaate til dens fremstilling

Info

Publication number
NO871816D0
NO871816D0 NO1987871816A NO871816A NO871816D0 NO 871816 D0 NO871816 D0 NO 871816D0 NO 1987871816 A NO1987871816 A NO 1987871816A NO 871816 A NO871816 A NO 871816A NO 871816 D0 NO871816 D0 NO 871816D0
Authority
NO
Norway
Prior art keywords
sod
superoxide dismutase
procedure
manufacturing
recovering
Prior art date
Application number
NO1987871816A
Other languages
English (en)
Other versions
NO871816L (no
NO301132B1 (no
Inventor
Stefan Marklund
Thomas Edlund
Original Assignee
Syn Tek Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syn Tek Ab filed Critical Syn Tek Ab
Publication of NO871816D0 publication Critical patent/NO871816D0/no
Publication of NO871816L publication Critical patent/NO871816L/no
Publication of NO301132B1 publication Critical patent/NO301132B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
NO871816A 1985-09-03 1987-04-30 Fremgangsmåte til fremstilling av superoksid dismutase NO301132B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK402785A DK402785D0 (da) 1985-09-03 1985-09-03 Fremgangsmaade til fremstilling af et enzym
PCT/DK1986/000098 WO1987001387A1 (en) 1985-09-03 1986-09-02 A superoxide dismutase

Publications (3)

Publication Number Publication Date
NO871816D0 true NO871816D0 (no) 1987-04-30
NO871816L NO871816L (no) 1987-07-02
NO301132B1 NO301132B1 (no) 1997-09-15

Family

ID=8129425

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871816A NO301132B1 (no) 1985-09-03 1987-04-30 Fremgangsmåte til fremstilling av superoksid dismutase

Country Status (18)

Country Link
US (1) US5130245A (no)
EP (1) EP0236385B1 (no)
JP (2) JP2643934B2 (no)
KR (1) KR920008738B1 (no)
CN (1) CN1030718C (no)
AT (1) ATE69466T1 (no)
AU (1) AU598756B2 (no)
CA (1) CA1340329C (no)
DE (1) DE3682505D1 (no)
DK (2) DK402785D0 (no)
FI (1) FI100252B (no)
HU (1) HU215937B (no)
IE (1) IE59078B1 (no)
IL (1) IL79926A (no)
NO (1) NO301132B1 (no)
SU (1) SU1779263A3 (no)
WO (1) WO1987001387A1 (no)
ZA (1) ZA871267B (no)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213628A3 (en) * 1985-09-03 1988-09-21 Yeda Research And Development Company, Ltd. Expression of superoxide dismutase in eukaryotic cells
US6610520B1 (en) 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS63132820A (ja) * 1986-11-22 1988-06-04 Minoru Nakano 口腔用組成物
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
EP0676472A1 (de) * 1987-03-14 1995-10-11 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Humane Mangan-Superoxiddismutase (hMn-SOD)
EP0284105B1 (en) * 1987-03-27 1995-11-15 Bio-Technology General Corporation Human manganese superoxide dismutase and methods of treatment
DK310788A (da) * 1987-06-09 1988-12-10 Int Cardiovascular Med Inc Praeparat indeholdende superoxid-dismutase, dets fremstilling og anvendelse til behandling af global iskaemi
JPH01238537A (ja) * 1988-03-18 1989-09-22 Toyo Jozo Co Ltd 肝障害治療剤
JPH01246225A (ja) * 1988-03-28 1989-10-02 Toyo Jozo Co Ltd 膵炎治療剤
JPH0262829A (ja) * 1988-05-18 1990-03-02 Nippon Kayaku Co Ltd 虚血に基づく傷害の予防及び治療剤
DK455789D0 (da) * 1989-09-15 1989-09-15 Symbicom Ab Polypeptid
DE4038563A1 (de) * 1990-12-04 1992-06-11 Gruenenthal Gmbh Verwendung von superoxiddismutasen zur prophylaxe und/oder behandlung von organversagen bei risikopatienten mit polytrauma
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
EP0627486A1 (en) * 1993-06-04 1994-12-07 N.V. Innogenetics S.A. New extracellular superoxide dismutase, a process for preparing the same and compositions containing the same
DK75393D0 (da) * 1993-06-24 1993-06-24 Symbicom Ab Production of protein
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
US6127356A (en) * 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
DE4336641C2 (de) * 1993-10-22 1995-09-07 Deutsches Rheuma Forschungszen Verwendung von Superoxid-Dismutase (SOD) zur Behandlung retroviraler Erkrankungen
AU3758695A (en) * 1994-09-20 1996-04-09 Duke University Oxidoreductase activity of manganic porphyrins
CA2204493C (en) 1994-11-04 2009-04-14 Hermann Katinger Application of superoxide dismutase in liposomes
MY128323A (en) * 1996-09-30 2007-01-31 Otsuka Pharma Co Ltd Thiazole derivatives for inhibition of cytokine production and of cell adhesion
AU8671798A (en) * 1997-07-30 1999-02-22 Betagene, Inc. Methods and compositions relating to no-mediated cytotoxicity
US6171856B1 (en) 1997-07-30 2001-01-09 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
ES2198767T3 (es) 1997-11-03 2004-02-01 Duke University Porfirinas sustituidas.
ATE311206T1 (de) 1998-04-24 2005-12-15 Univ Duke Substituierte porphyrine
JP4501128B2 (ja) * 1999-01-25 2010-07-14 ナショナル ジュウィッシュ ヘルス 置換ポルフィリン
CA2436245C (en) * 2001-01-19 2013-04-23 National Jewish Medical And Research Center Medicament for protection in radiotherapy
FI20010898A0 (fi) * 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
AU2002312194B8 (en) * 2001-06-01 2008-05-15 Aeolus Sciences, Inc. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
EP1499344A1 (en) * 2002-04-30 2005-01-26 FIT Biotech Oyj Plc Medical device
AU2003237500A1 (en) * 2002-06-07 2003-12-22 Duke University Substituted porphyrins
EP1692187B1 (en) * 2003-10-31 2012-06-27 Tae-Yoon Kim EC SOD and cell transducing EC SOD and use thereof
CN100345973C (zh) * 2004-11-18 2007-10-31 中国农业大学 超氧化物歧化酶基因的表达方法及其专用载体
EP2300003B1 (en) 2008-05-23 2014-03-05 National Jewish Health Compounds for use in treating injury associated with exposure to an alkylating species
US20100098768A1 (en) * 2008-10-16 2010-04-22 Clarkson University Method of neuroprotection from oxidant injury using metal oxide nanoparticles
CN102660580A (zh) * 2012-05-18 2012-09-12 深圳市北科生物科技有限公司 Sod基因修饰间充质干细胞的构建方法及其应用
MX363474B (es) * 2013-03-15 2019-03-25 Baxter Int Inmovilizacion de un agente activo en un sustrato.
CA2914732C (en) 2013-06-07 2019-06-25 Baxter International Inc. Immobilization of an active agent on a substrate using compounds including trihydroxyphenyl groups
CN104342409B (zh) * 2014-06-17 2018-05-25 吉林金梓源生物科技股份有限公司 重组人参超氧化物歧化酶的制备方法
CN104342408B (zh) * 2014-06-18 2018-05-25 吉林金梓源生物科技股份有限公司 重组蛹虫草超氧化物歧化酶的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145950C (da) * 1979-05-17 1983-09-26 Forenede Bryggerier As Fremgangsmaade til isolering af cu,zn-superoxid-dismutase fra vandige oploesninger indeholdende dette enzym sammen med ledsagende proteiner
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
JPS5729285A (en) * 1980-07-30 1982-02-17 Takeda Chem Ind Ltd Superoxide dismutase and its preparation
JPS57155991A (en) * 1981-03-23 1982-09-27 Green Cross Corp:The Preparation of superoxide dismutase derived from human placenta
EP0091539B2 (en) * 1982-03-31 1996-11-27 Ajinomoto Co., Inc. Gene coding for interleukin-2 polypeptide, recombinant DNA carrying said gene, cell lines possessing the recombinant DNA,and method for producing interleukin-2 using said cells
IT1150598B (it) * 1982-12-14 1986-12-17 Ines Bianchi Procedimento per la purificazione della superossidodismutasi mediante cromatografia di affinita'
ATE155527T1 (de) * 1983-10-03 1997-08-15 Chiron Corp Superoxiddismutase und deren expression in mikroorganismen
JPS61111690A (ja) * 1984-11-06 1986-05-29 Ube Ind Ltd 組換えｄｎａおよびその用途
JPS61139390A (ja) * 1984-12-13 1986-06-26 Nippon Kayaku Co Ltd ひとｓｏｄをコ−ドする新規ｄｎａおよびそれを有する微生物

Also Published As

Publication number Publication date
WO1987001387A1 (en) 1987-03-12
DE3682505D1 (de) 1991-12-19
US5130245A (en) 1992-07-14
FI871853A (fi) 1987-04-28
ZA871267B (en) 1987-10-28
JPH08317793A (ja) 1996-12-03
IL79926A0 (en) 1986-12-31
FI871853A0 (fi) 1987-04-28
CN86106774A (zh) 1987-07-15
NO871816L (no) 1987-07-02
JP2688190B2 (ja) 1997-12-08
AU6370886A (en) 1987-03-24
FI100252B (fi) 1997-10-31
HUT46059A (en) 1988-09-28
DK402785D0 (da) 1985-09-03
CN1030718C (zh) 1996-01-17
EP0236385B1 (en) 1991-11-13
ATE69466T1 (de) 1991-11-15
JPS63501473A (ja) 1988-06-09
IE862342L (en) 1987-03-03
HU215937B (hu) 1999-03-29
KR880700066A (ko) 1988-02-15
NO301132B1 (no) 1997-09-15
DK224587A (da) 1987-05-01
CA1340329C (en) 1999-01-26
JP2643934B2 (ja) 1997-08-25
AU598756B2 (en) 1990-07-05
IE59078B1 (en) 1994-01-12
KR920008738B1 (ko) 1992-10-08
SU1779263A3 (ru) 1992-11-30
DK224587D0 (da) 1987-05-01
EP0236385A1 (en) 1987-09-16
IL79926A (en) 1994-10-07

Similar Documents

Publication Publication Date Title
NO871816L (no) Superoksid dismutase og fremgangsmaate til dens fremstilling.
DK219087A (da) Vektorsystem til brug ved transformation af trichoderma, transformerede trichodermastammer og fremgangsmaade til fremstilling af proteiner heri
AU6329694A (en) Recombinant expression vectors and purification methods for thermus thermophilus DNA polymerase
NO176665C (no) Fremgangsmåte for fremstilling av ikke-glykosylert IL-6 og vektor for utskillelse derav
NZ219485A (en) Production of human endothelial cell growth factor comprising transforming a host cell with an expression vector
IL68366A (en) Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
DE69333802T8 (de) Äusseres membranprotein von haemophilus
JPS56148287A (en) Recovery of enzyme from blood
DK21184D0 (da) Fremgangsmade til fremstilling af human vaevsplasminogenaktivator (tpa) i vaertsceller,udtrykkelsesvektor for tpa og et dhfr-protein,celler transformeret med vektoren,og fremgangsmade til foroegelse af vaertscellernes produktion af tpa
DK98884D0 (da) Human beta-nervevaekstfaktor og fremg. til fremst. deraf, dna-sekvens, som koder for faktoren, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farma. praeparat og anven. af faktoren til behand. af beskadigede nerver
IL80960A0 (en) Process for improving the expression of eukaryotic proteins
JPS6420095A (en) Polypeptide having anti-blood coagulating action
FI102191B (fi) Menetelmä 3-des-hydroksikystatiini C:n tuottamiseksi ja menetelmässä k äytettävä DNA-sekvenssi
NO912621D0 (no) Fremgangsmaate for innfoering av dna i animalske celler.
DK0422217T3 (da) Human, rekombinant, placental ribonucleaseinhibitor og fremgangsmåde til produktion
DE3850933D1 (de) Anticoagulatorisches Protein PP4-X, seine Herstellung und Verwendung.
KR880003000A (ko) 고수율 발현용 플라스미드 벡터(pHK-3) 및 이를 표현벡터로 하는 인간의 면역 인터페론 생산특성을 지닌 재조합 플라스미드 벡터(pKSγ3BH)의 제조방법
ES8801958A1 (es) Un procedimiento para la determinacion de virus de sida