DK0952218T3 - Enkeltkædet molekyle, der kan binde til flere antigener, dettes fremstilling og anvendelse - Google Patents

Enkeltkædet molekyle, der kan binde til flere antigener, dettes fremstilling og anvendelse

Info

Publication number
DK0952218T3
DK0952218T3 DK99106176T DK99106176T DK0952218T3 DK 0952218 T3 DK0952218 T3 DK 0952218T3 DK 99106176 T DK99106176 T DK 99106176T DK 99106176 T DK99106176 T DK 99106176T DK 0952218 T3 DK0952218 T3 DK 0952218T3
Authority
DK
Denmark
Prior art keywords
vectors
cells
chain molecule
multiple antigens
binding
Prior art date
Application number
DK99106176T
Other languages
Danish (da)
English (en)
Inventor
Hans-Harald Prof Dr Sedlacek
Rolf Prof Dr Mueller
Roland Dr Kontermann
Original Assignee
Affitech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26045416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0952218(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19816141A external-priority patent/DE19816141A1/de
Priority claimed from DE19827239A external-priority patent/DE19827239A1/de
Application filed by Affitech As filed Critical Affitech As
Application granted granted Critical
Publication of DK0952218T3 publication Critical patent/DK0952218T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007Carcino-embryonic Antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/626Diabody or triabody
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK99106176T 1998-04-09 1999-04-08 Enkeltkædet molekyle, der kan binde til flere antigener, dettes fremstilling og anvendelse DK0952218T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19816141A DE19816141A1 (de) 1998-04-09 1998-04-09 Einzelkettiges, mehrfach-antigenbindendes Molekül, dessen Herstellung und Verwendung
DE19827239A DE19827239A1 (de) 1998-06-18 1998-06-18 Einzelkettiges, mehrfach-antigenbindendes Molekül, dessen Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
DK0952218T3 true DK0952218T3 (da) 2009-02-09

Family

ID=26045416

Family Applications (2)

Application Number Title Priority Date Filing Date
DK99106176T DK0952218T3 (da) 1998-04-09 1999-04-08 Enkeltkædet molekyle, der kan binde til flere antigener, dettes fremstilling og anvendelse
DK08019619.9T DK2036926T3 (da) 1998-04-09 1999-04-08 Enkeltkædet molekyle, der kan binde til flere antigener, dettes fremstilling og anvendelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08019619.9T DK2036926T3 (da) 1998-04-09 1999-04-08 Enkeltkædet molekyle, der kan binde til flere antigener, dettes fremstilling og anvendelse

Country Status (17)

Country Link
US (3) US6759518B1 (pt)
EP (2) EP2036926B1 (pt)
JP (1) JP5306564B2 (pt)
KR (1) KR19990083043A (pt)
CN (1) CN1234406A (pt)
AT (1) ATE414150T1 (pt)
AU (2) AU767580C (pt)
BR (1) BR9902039A (pt)
CA (1) CA2268258C (pt)
CY (1) CY1108728T1 (pt)
CZ (1) CZ121599A3 (pt)
DE (1) DE59914902D1 (pt)
DK (2) DK0952218T3 (pt)
ES (1) ES2317680T3 (pt)
HK (1) HK1130498A1 (pt)
HU (1) HUP9900956A2 (pt)
PT (1) PT952218E (pt)

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