DK0550696T3
(da)
*
|
1990-09-28 |
2001-03-19 |
Hoffmann La Roche |
Oprenset termostabilt nukleinsyre-polymeraseenzym fra Thermosipho africanus
|
WO1992006188A2
(en)
*
|
1990-10-05 |
1992-04-16 |
Barnes Wayne M |
Thermostable dna polymerase
|
US6872816B1
(en)
|
1996-01-24 |
2005-03-29 |
Third Wave Technologies, Inc. |
Nucleic acid detection kits
|
US5994069A
(en)
|
1996-01-24 |
1999-11-30 |
Third Wave Technologies, Inc. |
Detection of nucleic acids by multiple sequential invasive cleavages
|
US5846717A
(en)
*
|
1996-01-24 |
1998-12-08 |
Third Wave Technologies, Inc. |
Detection of nucleic acid sequences by invader-directed cleavage
|
US5422253A
(en)
*
|
1992-12-07 |
1995-06-06 |
Wisconsin Alumni Research Foundation |
Method of site specific nucleic acid cleavage
|
US7601496B2
(en)
|
1992-12-07 |
2009-10-13 |
Third Wave Technologies, Inc. |
Cleavage of nucleic acids
|
US6372424B1
(en)
|
1995-08-30 |
2002-04-16 |
Third Wave Technologies, Inc |
Rapid detection and identification of pathogens
|
US5614402A
(en)
*
|
1992-12-07 |
1997-03-25 |
Third Wave Technologies, Inc. |
5' nucleases derived from thermostable DNA polymerase
|
US6673616B1
(en)
|
1992-12-07 |
2004-01-06 |
Third Wave Technologies, Inc. |
Methods and compositions for characterizing nucleic acids
|
US5719028A
(en)
*
|
1992-12-07 |
1998-02-17 |
Third Wave Technologies Inc. |
Cleavase fragment length polymorphism
|
US5843654A
(en)
*
|
1992-12-07 |
1998-12-01 |
Third Wave Technologies, Inc. |
Rapid detection of mutations in the p53 gene
|
US5888780A
(en)
*
|
1992-12-07 |
1999-03-30 |
Third Wave Technologies, Inc. |
Rapid detection and identification of nucleic acid variants
|
US5541311A
(en)
*
|
1992-12-07 |
1996-07-30 |
Third Wave Technologies, Inc. |
Nucleic acid encoding synthesis-deficient thermostable DNA polymerase
|
US5436149A
(en)
*
|
1993-02-19 |
1995-07-25 |
Barnes; Wayne M. |
Thermostable DNA polymerase with enhanced thermostability and enhanced length and efficiency of primer extension
|
US6410277B1
(en)
|
1993-02-19 |
2002-06-25 |
Takara Shuzo Co., Ltd. |
DNA polymersases with enhanced length of primer extension
|
US5474920A
(en)
*
|
1993-11-23 |
1995-12-12 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University |
Modified thermo-resistant DNA polymerases
|
US7312052B1
(en)
|
1993-12-08 |
2007-12-25 |
Stratagene California |
Polymerase compositions and uses thereof
|
US5648211A
(en)
*
|
1994-04-18 |
1997-07-15 |
Becton, Dickinson And Company |
Strand displacement amplification using thermophilic enzymes
|
US6015668A
(en)
*
|
1994-09-30 |
2000-01-18 |
Life Technologies, Inc. |
Cloned DNA polymerases from thermotoga and mutants thereof
|
US5912155A
(en)
*
|
1994-09-30 |
1999-06-15 |
Life Technologies, Inc. |
Cloned DNA polymerases from Thermotoga neapolitana
|
MX9703187A
(es)
|
1994-11-02 |
1998-02-28 |
Trophix Pharm Inc |
Canales de sodio especificos del sistema nervioso periferico, adn que codifica para mismos, cristalizacion, difraccion por rayos x, modelado molecular por computadora, diseño racional de farmacos seleccion de farmacos y metodos para la elaboracion y
|
AU4245096A
(en)
*
|
1994-11-04 |
1996-05-31 |
Molecular Biology Resources, Inc. |
Biologically active fragments of thermus flavus dna polymerase
|
US6440716B1
(en)
|
1995-02-03 |
2002-08-27 |
Novozymes A/S |
α-amylase mutants
|
DE69637940D1
(de)
*
|
1995-02-03 |
2009-07-09 |
Novozymes As |
Eine methode zum entwurf von alpha-amylase mutanten mit vorbestimmten eigenschaften
|
US5885813A
(en)
*
|
1995-05-31 |
1999-03-23 |
Amersham Life Science, Inc. |
Thermostable DNA polymerases
|
US6077664A
(en)
*
|
1995-06-07 |
2000-06-20 |
Promega Corporation |
Thermophilic DNA polymerases from Thermotoga neapolitana
|
US6001645A
(en)
*
|
1995-06-07 |
1999-12-14 |
Promega Corporation |
Thermophilic DNA polymerases from thermotoga neapolitana
|
US5770690A
(en)
*
|
1995-06-27 |
1998-06-23 |
Neurex Corporation |
Bax omega protein and methods
|
US5773258A
(en)
*
|
1995-08-25 |
1998-06-30 |
Roche Molecular Systems, Inc. |
Nucleic acid amplification using a reversibly inactivated thermostable enzyme
|
AU7236296A
(en)
*
|
1995-09-08 |
1997-03-27 |
Life Technologies, Inc. |
Cloned dna polymerases from thermotoga and mutants thereof
|
DE69613856T2
(de)
*
|
1995-12-15 |
2002-04-04 |
Amersham Pharmacia Biotech Inc., Piscataway |
Thermostabile dna polymerase aus thermoanaerobacter thermohydrosulfuricus und davon abgeleitete mutierte enzyme mit entfernter exonukleaseaktivität
|
US6562611B1
(en)
|
1996-11-29 |
2003-05-13 |
Third Wave Technologies, Ins. |
FEN-1 endonucleases, mixtures and cleavage methods
|
US6090606A
(en)
*
|
1996-01-24 |
2000-07-18 |
Third Wave Technologies, Inc. |
Cleavage agents
|
US6706471B1
(en)
|
1996-01-24 |
2004-03-16 |
Third Wave Technologies, Inc. |
Detection of nucleic acid sequences by invader-directed cleavage
|
US6875572B2
(en)
|
1996-01-24 |
2005-04-05 |
Third Wave Technologies, Inc. |
Nucleic acid detection assays
|
US5985557A
(en)
|
1996-01-24 |
1999-11-16 |
Third Wave Technologies, Inc. |
Invasive cleavage of nucleic acids
|
US7195871B2
(en)
|
1996-01-24 |
2007-03-27 |
Third Wave Technologies, Inc |
Methods and compositions for detecting target sequences
|
US7122364B1
(en)
|
1998-03-24 |
2006-10-17 |
Third Wave Technologies, Inc. |
FEN endonucleases
|
WO1998006736A1
(en)
|
1996-08-14 |
1998-02-19 |
Life Technologies, Inc. |
Stable compositions for nucleic acid amplification and sequencing
|
US6306588B1
(en)
|
1997-02-07 |
2001-10-23 |
Invitrogen Corporation |
Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
|
DE69838724T2
(de)
|
1997-03-21 |
2008-10-30 |
Stratagene California, La Jolla |
Polymerase-verbessernder faktor (pef)-enthaltende extrakte, pef proteinkomplexe, isoliertes pef protein und verfahren zur reinigung und identifizierung
|
EP2354251B1
(en)
|
1997-04-03 |
2014-10-15 |
Life Technologies Corporation |
Compositons and methods for reverse transcriptase-Polymerase chain reaction (RT-PCR)
|
CA2287542A1
(en)
|
1997-04-22 |
1998-10-29 |
Life Technologies, Inc. |
Methods for the production of aslv reverse transcriptases composed of multiple subunits
|
US6228628B1
(en)
*
|
1997-07-09 |
2001-05-08 |
Roche Molecular Systems |
Mutant chimeric DNA polymerase
|
US6140086A
(en)
*
|
1997-08-15 |
2000-10-31 |
Fox; Donna K. |
Methods and compositions for cloning nucleic acid molecules
|
EP1012161B1
(en)
|
1997-08-29 |
2011-03-16 |
Life Technologies Corporation |
High fidelity polymerases and uses thereof
|
US8182991B1
(en)
|
1997-11-26 |
2012-05-22 |
Third Wave Technologies, Inc. |
FEN-1 endonucleases, mixtures and cleavage methods
|
EP0921196A1
(en)
|
1997-12-02 |
1999-06-09 |
Roche Diagnostics GmbH |
Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
|
US6787305B1
(en)
|
1998-03-13 |
2004-09-07 |
Invitrogen Corporation |
Compositions and methods for enhanced synthesis of nucleic acid molecules
|
US6130045A
(en)
*
|
1998-06-11 |
2000-10-10 |
Clontech Laboratories, Inc. |
Thermostable polymerase
|
PT1129064E
(pt)
|
1998-11-12 |
2008-01-31 |
Invitrogen Corp |
Reagentes de transfecção
|
CA2374515A1
(en)
|
1999-05-21 |
2000-11-30 |
Christian E. Gruber |
Compositions and methods for labeling of nucleic acid molecules
|
WO2000079009A2
(en)
|
1999-06-22 |
2000-12-28 |
Invitrogen Corporation |
Improved primers and methods for the detection and discrimination of nucleic acids
|
US6830902B1
(en)
|
1999-07-02 |
2004-12-14 |
Invitrogen Corporation |
Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
|
GB9918150D0
(en)
*
|
1999-08-03 |
1999-10-06 |
Univ Sheffield |
Nuclease variant
|
GB9921318D0
(en)
*
|
1999-09-09 |
1999-11-10 |
Kristensen Tom |
Chimeric molecules
|
US7838225B2
(en)
|
1999-10-29 |
2010-11-23 |
Hologic, Inc. |
Methods for detection of a target nucleic acid by forming a cleavage structure using a reverse transcriptase
|
US7118860B2
(en)
|
1999-10-29 |
2006-10-10 |
Stratagene California |
Methods for detection of a target nucleic acid by capture
|
US7824859B2
(en)
|
1999-10-29 |
2010-11-02 |
Cytyc Corporation |
Methods for detection of a target nucleic acid by forming a cleavage structure using an RNA polymerase
|
CN1757724B
(zh)
|
1999-12-10 |
2014-06-11 |
茵维特罗根公司 |
具有独特特异性的多个重组位点在重组克隆中的用途
|
EP1259624B1
(en)
|
2000-02-17 |
2008-05-14 |
Qiagen GmbH |
Thermostable chimeric nucleic acid polymerases and uses thereof
|
US6436677B1
(en)
|
2000-03-02 |
2002-08-20 |
Promega Corporation |
Method of reverse transcription
|
US6632645B1
(en)
|
2000-03-02 |
2003-10-14 |
Promega Corporation |
Thermophilic DNA polymerases from Thermoactinomyces vulgaris
|
EP2295551B1
(en)
|
2000-05-26 |
2016-04-06 |
Life Technologies Corporation |
Thermostable reverse transcriptases and uses thereof
|
AU2002218749A1
(en)
*
|
2000-07-12 |
2002-01-21 |
Invitrogen Corporation |
High fidelity polymerases and uses thereof
|
US7198924B2
(en)
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
DE10049211A1
(de)
|
2000-10-05 |
2002-04-18 |
Qiagen Gmbh |
Thermostabile Polymerase aus Thermococcus pacificus
|
EP1548130B1
(en)
|
2000-11-15 |
2012-01-18 |
Third Wave Technologies, Inc. |
Fen endonucleases
|
CA2430947A1
(en)
|
2000-12-08 |
2002-06-13 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
US20030165859A1
(en)
|
2001-10-23 |
2003-09-04 |
Invitrogen Corporation |
Primers and methods for the detection and discrimination of nucleic acids
|
AU2002346517A1
(en)
*
|
2001-11-30 |
2003-06-17 |
Applera Corporation |
Thermus oshimai nucleic acid polymerases
|
GB0205455D0
(en)
|
2002-03-07 |
2002-04-24 |
Molecular Sensing Plc |
Nucleic acid probes, their synthesis and use
|
EP2345738A1
(en)
|
2002-08-05 |
2011-07-20 |
Quanta Biosciences, Inc. |
Improved compositions for in vitro amplification of nucleic acids
|
EP2325303B1
(en)
|
2002-09-13 |
2013-11-06 |
Life Technologies Corporation |
Thermostable reverse transcriptases and uses thereof
|
WO2004027025A2
(en)
*
|
2002-09-20 |
2004-04-01 |
New England Biolabs, Inc. |
Helicase dependent amplification of nucleic acids
|
DE602004025801D1
(de)
|
2003-03-25 |
2010-04-15 |
Stratagene California |
Dna-polymerasefusionen und deren verwendungen
|
KR100890885B1
(ko)
|
2003-03-31 |
2009-03-31 |
에프. 호프만-라 로슈 아게 |
일본 뇌염 바이러스 혈청군의 구성원을 포함하는, 특정플라비바이러스 검출용 조성물 및 방법
|
AU2004203649B2
(en)
*
|
2003-08-12 |
2006-01-12 |
F. Hoffmann-La Roche Ag |
Thermostable Taq polymerase fragment
|
EP1697534B1
(en)
|
2003-12-01 |
2010-06-02 |
Life Technologies Corporation |
Nucleic acid molecules containing recombination sites and methods of using the same
|
CA2560513A1
(en)
|
2004-04-08 |
2005-12-01 |
Biomatrica, Inc. |
Integration of sample storage and sample management for life science
|
US7943294B2
(en)
|
2004-07-30 |
2011-05-17 |
Hologic, Inc. |
Methods for detecting oncofetal fibronectin
|
US9505846B2
(en)
|
2005-01-28 |
2016-11-29 |
Life Technologies Corporation |
Multi-component inhibitors of nucleic acid polymerases
|
US20060292578A1
(en)
|
2005-06-28 |
2006-12-28 |
Weidong Zheng |
DNA polymerase blends and mutant DNA polymerases
|
JP2007104909A
(ja)
*
|
2005-10-11 |
2007-04-26 |
Tama Tlo Kk |
好熱性細菌サーマス・カワライェンシス由来耐熱性dnaポリメラーゼ
|
US8962293B2
(en)
|
2006-10-18 |
2015-02-24 |
Roche Molecular Systems, Inc. |
DNA polymerases and related methods
|
CA2639416C
(en)
|
2007-09-11 |
2019-12-31 |
F. Hoffmann-La Roche Ag |
Diagnostic test for susceptibility to b-raf kinase inhibitors
|
GB0803628D0
(en)
|
2008-02-28 |
2008-04-02 |
Genesys Ltd |
Enzyme
|
BRPI0908748A2
(pt)
|
2008-03-15 |
2015-07-28 |
Hologic Inc |
Composições e métodos para análise de moléculas de ácido nucleico durante reações de amplificação
|
US10150990B2
(en)
|
2008-04-21 |
2018-12-11 |
Roche Molecular Systems, Inc. |
Ribonucleotide tag nucleic acid detection
|
US20100159452A1
(en)
*
|
2008-12-22 |
2010-06-24 |
Roche Molecular Systems, Inc. |
Method For Detecting a Target Nucleic Acid in a Sample
|
EP2392680A1
(en)
|
2010-06-04 |
2011-12-07 |
Labor Diagnostik GmbH Leipzig |
Method for specific detection of classical swine fever virus
|
CA2802302C
(en)
|
2010-06-18 |
2016-04-26 |
F. Hoffman-La Roche Ag |
Dna polymerases with increased 3'-mismatch discrimination
|
EP2582804B1
(en)
|
2010-06-18 |
2015-02-25 |
Roche Diagnostics GmbH |
Dna polymerases with increased 3'-mismatch discrimination
|
JP5926248B2
(ja)
|
2010-06-18 |
2016-05-25 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
増大した3’末端ミスマッチ識別能を有するdnaポリメラーゼ
|
US8759062B2
(en)
|
2010-06-18 |
2014-06-24 |
Roche Molecular Systems, Inc. |
DNA polymerases with increased 3′- mismatch discrimination
|
WO2011157434A1
(en)
|
2010-06-18 |
2011-12-22 |
Roche Diagnostics Gmbh |
Dna polymerases with increased 3'-mismatch discrimination
|
WO2011157432A1
(en)
|
2010-06-18 |
2011-12-22 |
Roche Diagnostics Gmbh |
Dna polymerases with increased 3'-mismatch discrimination
|
WO2011157438A1
(en)
|
2010-06-18 |
2011-12-22 |
Roche Diagnostics Gmbh |
Dna polymerases with increasesed 3'-mismatch discrimination
|
CA2802239C
(en)
|
2010-06-18 |
2016-08-23 |
F. Hoffmann-La Roche Ag |
Dna polymerases with increased 3'-mismatch discrimination
|
WO2011163120A1
(en)
|
2010-06-21 |
2011-12-29 |
Life Technologies Corporation |
Compositions, methods and kits for nucleic acid synthesis and amplification
|
US9410194B2
(en)
|
2010-06-21 |
2016-08-09 |
Life Technologies Corporation |
Compositions, kits and methods for synthesis and/or detection of nucleic acids
|
EP2598660B1
(en)
|
2010-07-26 |
2017-03-15 |
Biomatrica, INC. |
Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
|
WO2012018639A2
(en)
|
2010-07-26 |
2012-02-09 |
Biomatrica, Inc. |
Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
|
EP2606149B1
(en)
|
2010-08-20 |
2017-08-02 |
Life Technologies Corporation |
Polymerase assay with a fret substrate
|
WO2012024642A1
(en)
|
2010-08-20 |
2012-02-23 |
Life Technologies Corporation |
Quantitative real-time pcr assay using fret dual-labeled primers
|
US8765435B2
(en)
|
2011-02-15 |
2014-07-01 |
Roche Molecular Systems, Inc. |
DNA polymerases with increased 3′-mismatch discrimination
|
CN103492559B
(zh)
|
2011-04-11 |
2016-07-06 |
霍夫曼-拉罗奇有限公司 |
具有改进活性的dna聚合酶
|
US8715987B2
(en)
|
2011-05-02 |
2014-05-06 |
New England Biolabs, Inc. |
Solubilized phospholipids for stabilizing nucleic acid polymerases
|
WO2012159025A2
(en)
|
2011-05-18 |
2012-11-22 |
Life Technologies Corporation |
Chromosome conformation analysis
|
US9567628B2
(en)
|
2011-06-08 |
2017-02-14 |
Life Technologies Corporation |
Polymerization of nucleic acids using proteins having low isoelectric points
|
WO2012170908A1
(en)
|
2011-06-08 |
2012-12-13 |
Life Technologies Corporation |
Design and development of novel detergents for use in pcr systems
|
JP5830286B2
(ja)
|
2011-07-12 |
2015-12-09 |
アークレイ株式会社 |
核酸の増幅検出方法およびキット
|
JP5977000B2
(ja)
|
2011-07-12 |
2016-08-24 |
アークレイ株式会社 |
核酸の増幅検出方法およびキット
|
US9447388B2
(en)
|
2011-07-12 |
2016-09-20 |
Kyushu University, National University Corporation |
DNA polymerases
|
CA2853829C
(en)
|
2011-07-22 |
2023-09-26 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
ES2553400T3
(es)
|
2011-07-28 |
2015-12-09 |
F. Hoffmann-La Roche Ag |
ADN polimerasas con actividad mejorada
|
US11208636B2
(en)
|
2011-08-10 |
2021-12-28 |
Life Technologies Corporation |
Polymerase compositions, methods of making and using same
|
CN103857805B
(zh)
*
|
2011-08-10 |
2017-07-18 |
生命技术公司 |
聚合酶组合物、制备和使用所述聚合酶组合物的方法
|
ES2668448T3
(es)
|
2011-12-08 |
2018-05-18 |
F. Hoffmann-La Roche Ag |
ADN polimerasas con actividad mejorada
|
JP6140182B2
(ja)
|
2011-12-08 |
2017-05-31 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
改善された活性を有するdnaポリメラーゼ
|
JP6224613B2
(ja)
|
2011-12-08 |
2017-11-01 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
改善された活性を有するdnaポリメラーゼ
|
EP2909319B1
(en)
|
2012-10-16 |
2018-05-23 |
DNA Polymerase Technology, Inc. |
Inhibition-resistant polymerases
|
US9416405B2
(en)
|
2012-11-02 |
2016-08-16 |
Life Technologies Corporation |
Compositions, methods and kits for enhancing PCR specificity
|
US9725703B2
(en)
|
2012-12-20 |
2017-08-08 |
Biomatrica, Inc. |
Formulations and methods for stabilizing PCR reagents
|
US11254977B2
(en)
|
2013-03-12 |
2022-02-22 |
Life Technologies Corporation |
Universal reporter-based genotyping methods and materials
|
US9828629B2
(en)
|
2013-03-15 |
2017-11-28 |
Roche Molecular Systems, Inc. |
Nucleic acid target identification by structure based probe cleavage
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
US9228207B2
(en)
|
2013-09-06 |
2016-01-05 |
President And Fellows Of Harvard College |
Switchable gRNAs comprising aptamers
|
WO2015061714A1
(en)
|
2013-10-25 |
2015-04-30 |
Life Technologies Corporation |
Novel compounds for use in pcr systems and applications thereof
|
US9637791B2
(en)
|
2013-12-20 |
2017-05-02 |
Roche Molecular Systems, Inc. |
Multiplexed nucleic acid target identification by strucutre based probe cleavage
|
US20150176060A1
(en)
|
2013-12-20 |
2015-06-25 |
Roche Molecular Systems, Inc. |
Method For Coding Of Multiple PCR Reactions For Assay Recognition
|
US9243289B2
(en)
|
2013-12-23 |
2016-01-26 |
Roche Molecular Systems, Inc. |
Method for screening reagents used in PCR assays
|
US20160053302A1
(en)
|
2014-04-22 |
2016-02-25 |
Roche Molecular Systems, Inc. |
Method for visual identification of pcr solutions for accurate reaction setup
|
EP3154338B1
(en)
|
2014-06-10 |
2020-01-29 |
Biomatrica, INC. |
Stabilization of thrombocytes at ambient temperatures
|
WO2016011203A1
(en)
|
2014-07-15 |
2016-01-21 |
Life Technologies Corporation |
Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
|
US10077453B2
(en)
|
2014-07-30 |
2018-09-18 |
President And Fellows Of Harvard College |
CAS9 proteins including ligand-dependent inteins
|
WO2016126987A1
(en)
*
|
2015-02-04 |
2016-08-11 |
Twist Bioscience Corporation |
Compositions and methods for synthetic gene assembly
|
CN107429296B
(zh)
|
2015-03-13 |
2022-01-28 |
生命技术公司 |
捕获、检测和定量小rna的方法、组合物与试剂盒
|
US11091745B2
(en)
|
2015-05-12 |
2021-08-17 |
Dna Polymerase Technology, Inc. |
Mutant polymerases and uses thereof
|
CN116218815A
(zh)
|
2015-10-01 |
2023-06-06 |
生命技术公司 |
聚合酶组合物和套组以及其使用与制造方法
|
IL294014B2
(en)
|
2015-10-23 |
2024-07-01 |
Harvard College |
Nucleobase editors and their uses
|
JP6827048B2
(ja)
|
2015-12-08 |
2021-02-10 |
バイオマトリカ,インク. |
赤血球沈降速度の低下
|
RU2757416C2
(ru)
|
2016-04-06 |
2021-10-15 |
Лайф Текнолоджис Корпорейшн |
Композиции, способы и наборы для синтеза и обнаружения нуклеиновых кислот
|
ES2929367T3
(es)
|
2016-05-18 |
2022-11-28 |
Hoffmann La Roche |
Amplificación por PCR ultrarrápida cuantitativa usando un dispositivo basado en electrohumectación
|
EP3472349A1
(en)
|
2016-06-16 |
2019-04-24 |
Life Technologies Corporation |
Novel compositions, methods and kits for microorganism detection
|
IL308426A
(en)
|
2016-08-03 |
2024-01-01 |
Harvard College |
Adenosine nuclear base editors and their uses
|
US11661590B2
(en)
|
2016-08-09 |
2023-05-30 |
President And Fellows Of Harvard College |
Programmable CAS9-recombinase fusion proteins and uses thereof
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
CN118207299A
(zh)
|
2016-08-26 |
2024-06-18 |
生命技术公司 |
核酸提取和扩增对照及其使用方法
|
KR102468174B1
(ko)
|
2016-09-15 |
2022-11-17 |
에프. 호프만-라 로슈 아게 |
멀티플렉스 pcr 수행 방법
|
SG11201903089RA
(en)
|
2016-10-14 |
2019-05-30 |
Harvard College |
Aav delivery of nucleobase editors
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
EP3592777A1
(en)
|
2017-03-10 |
2020-01-15 |
President and Fellows of Harvard College |
Cytosine to guanine base editor
|
JP7191388B2
(ja)
|
2017-03-23 |
2022-12-19 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
核酸によってプログラム可能なdna結合蛋白質を含む核酸塩基編集因子
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
US11319532B2
(en)
|
2017-08-30 |
2022-05-03 |
President And Fellows Of Harvard College |
High efficiency base editors comprising Gam
|
CN111757937A
(zh)
|
2017-10-16 |
2020-10-09 |
布罗德研究所股份有限公司 |
腺苷碱基编辑器的用途
|
US20200340041A1
(en)
|
2017-11-13 |
2020-10-29 |
Life Technologies Corporation |
Novel compositions, methods and kits for urinary tract microorganism detection
|
CN112703248A
(zh)
|
2018-09-13 |
2021-04-23 |
豪夫迈·罗氏有限公司 |
具有改良链置换能力的突变型dna聚合酶
|
WO2020127620A1
(en)
|
2018-12-20 |
2020-06-25 |
F. Hoffmann-La Roche Ag |
Detection of target nucleic acid by solid-phase molography
|
WO2020191243A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
DE112021002672T5
(de)
|
2020-05-08 |
2023-04-13 |
President And Fellows Of Harvard College |
Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz
|
US20230272462A1
(en)
*
|
2020-07-09 |
2023-08-31 |
University Of Washington |
Kits, methods, polypeptides, systems, and non-transitory, machine-readable storage media for detecting a nucleic acid
|
WO2022018685A1
(en)
|
2020-07-22 |
2022-01-27 |
King Abdullah University Of Science And Technology |
Compositions and methods for one-step nucleic acid amplification and diagnostic methods based thereon
|
CA3193099A1
(en)
|
2020-09-24 |
2022-03-31 |
David R. Liu |
Prime editing guide rnas, compositions thereof, and methods of using the same
|
WO2022074058A1
(en)
|
2020-10-06 |
2022-04-14 |
Keygene N.V. |
Targeted sequence addition
|
JP2024500169A
(ja)
|
2020-12-22 |
2024-01-04 |
エフ. ホフマン-ラ ロシュ アーゲー |
大ストークスシフト蛍光色素を使用して多重化リアルタイムpcrを行うための方法
|
AU2022206476A1
(en)
|
2021-01-11 |
2023-07-20 |
President And Fellows Of Harvard College |
Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
|
WO2023076898A1
(en)
|
2021-10-25 |
2023-05-04 |
The Broad Institute, Inc. |
Methods and compositions for editing a genome with prime editing and a recombinase
|
EP4444904A1
(en)
|
2021-12-09 |
2024-10-16 |
F. Hoffmann-La Roche AG |
Mass based detection of pcr amplicons
|
WO2024108092A1
(en)
|
2022-11-17 |
2024-05-23 |
The Broad Institute, Inc. |
Prime editor delivery by aav
|
WO2024138087A2
(en)
|
2022-12-23 |
2024-06-27 |
The Broad Institute, Inc. |
Methods and compositions for modulating cellular factors to increase prime editing efficiencies
|
WO2024155741A1
(en)
|
2023-01-18 |
2024-07-25 |
The Broad Institute, Inc. |
Prime editing-mediated readthrough of premature termination codons (pert)
|