MX9703187A - Canales de sodio especificos del sistema nervioso periferico, adn que codifica para mismos, cristalizacion, difraccion por rayos x, modelado molecular por computadora, diseño racional de farmacos seleccion de farmacos y metodos para la elaboracion y - Google Patents

Canales de sodio especificos del sistema nervioso periferico, adn que codifica para mismos, cristalizacion, difraccion por rayos x, modelado molecular por computadora, diseño racional de farmacos seleccion de farmacos y metodos para la elaboracion y

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Publication number
MX9703187A
MX9703187A MX9703187A MX9703187A MX9703187A MX 9703187 A MX9703187 A MX 9703187A MX 9703187 A MX9703187 A MX 9703187A MX 9703187 A MX9703187 A MX 9703187A MX 9703187 A MX9703187 A MX 9703187A
Authority
MX
Mexico
Prior art keywords
nervous system
peripheral nervous
system specific
making
methods
Prior art date
Application number
MX9703187A
Other languages
English (en)
Inventor
Gail Mandel
Simon Halegoua
Laurence A Borden
Original Assignee
Trophix Pharm Inc
Res Foundation Of State
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26989015&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9703187(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trophix Pharm Inc, Res Foundation Of State, Univ New York filed Critical Trophix Pharm Inc
Publication of MX9703187A publication Critical patent/MX9703187A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describen la clonacion, expresion, y los vectores y huéspedes virales y de distribucion que contienen el ácido nucleico que codifica para al menos un péptido de los canales de sodio (SCP) específico del sistema nervioso periférico (PNS), el SCP de PNS aislado, y los compuestos y composiciones y métodos, para el aislamiento, cristalizacion, modelacion molecular por análisis de rayos X, diseño racional de fármacos, seleccion, elaboracion y uso de agentes terapéuticos o diagnosticos o ligandos que tienen al menos una actividad moduladora del canal de sodio (SC) específico del sistema nervioso periférico (PNS).
MX9703187A 1994-11-02 1995-11-02 Canales de sodio especificos del sistema nervioso periferico, adn que codifica para mismos, cristalizacion, difraccion por rayos x, modelado molecular por computadora, diseño racional de farmacos seleccion de farmacos y metodos para la elaboracion y MX9703187A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33402994A 1994-11-02 1994-11-02
US48240195A 1995-06-07 1995-06-07
PCT/US1995/014251 WO1996014077A1 (en) 1994-11-02 1995-11-02 Peripheral nervous system specific sodium channels, dna encoding therefor, crystallization, x-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof

Publications (1)

Publication Number Publication Date
MX9703187A true MX9703187A (es) 1998-02-28

Family

ID=26989015

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9703187A MX9703187A (es) 1994-11-02 1995-11-02 Canales de sodio especificos del sistema nervioso periferico, adn que codifica para mismos, cristalizacion, difraccion por rayos x, modelado molecular por computadora, diseño racional de farmacos seleccion de farmacos y metodos para la elaboracion y

Country Status (13)

Country Link
US (5) US6110672A (es)
EP (2) EP0789575B8 (es)
JP (5) JP2000503521A (es)
AT (1) ATE407207T1 (es)
AU (1) AU697465B2 (es)
CA (1) CA2204355C (es)
DE (1) DE69535830D1 (es)
DK (1) DK0789575T3 (es)
ES (1) ES2314978T3 (es)
MX (1) MX9703187A (es)
NZ (1) NZ296748A (es)
PT (1) PT789575E (es)
WO (1) WO1996014077A1 (es)

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WO2002002608A2 (en) * 2000-07-05 2002-01-10 Neurosearch A/S NEW SODIUM CHANNEL (rNaV1.5a) AND USE THEREOF
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AU2001294141A1 (en) * 2000-09-19 2002-04-02 Gbf Gesellschaft Fur Biotechnologische Forschung Mbh Crystalline fgf9 dimer and methods of use
DE10054878A1 (de) * 2000-11-06 2002-05-08 Boehringer Ingelheim Int Natriumkanäle vom Typus der peripheren Nerven
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Also Published As

Publication number Publication date
EP1985703A2 (en) 2008-10-29
ATE407207T1 (de) 2008-09-15
US8012748B2 (en) 2011-09-06
EP1985703A3 (en) 2009-04-08
EP0789575B8 (en) 2009-01-14
JP2009055921A (ja) 2009-03-19
JP2009118844A (ja) 2009-06-04
ES2314978T3 (es) 2009-03-16
US20030092645A1 (en) 2003-05-15
NZ296748A (en) 1999-11-29
EP0789575A4 (en) 2000-11-08
WO1996014077A1 (en) 1996-05-17
JP2000503521A (ja) 2000-03-28
JP2003047484A (ja) 2003-02-18
AU4143496A (en) 1996-05-31
EP0789575A1 (en) 1997-08-20
US6110672A (en) 2000-08-29
PT789575E (pt) 2008-12-15
US6703486B2 (en) 2004-03-09
EP0789575B1 (en) 2008-09-03
CA2204355C (en) 2001-01-16
CA2204355A1 (en) 1996-05-17
US20090029415A1 (en) 2009-01-29
AU697465B2 (en) 1998-10-08
US20090203122A1 (en) 2009-08-13
DK0789575T3 (da) 2009-01-12
US20040229792A1 (en) 2004-11-18
DE69535830D1 (de) 2008-10-16
JP2007169286A (ja) 2007-07-05

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