DE69819345T2 - Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung - Google Patents
Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung Download PDFInfo
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- DE69819345T2 DE69819345T2 DE69819345T DE69819345T DE69819345T2 DE 69819345 T2 DE69819345 T2 DE 69819345T2 DE 69819345 T DE69819345 T DE 69819345T DE 69819345 T DE69819345 T DE 69819345T DE 69819345 T2 DE69819345 T2 DE 69819345T2
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- capsaicin receptor
- capsaicin
- polypeptide
- vanilloid
- receptor
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US915461 | 1986-10-06 | ||
| US91546197A | 1997-08-20 | 1997-08-20 | |
| US7215198P | 1998-01-22 | 1998-01-22 | |
| US72151P | 1998-01-22 | ||
| PCT/US1998/017466 WO1999009140A1 (en) | 1997-08-20 | 1998-08-20 | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69819345D1 DE69819345D1 (de) | 2003-12-04 |
| DE69819345T2 true DE69819345T2 (de) | 2004-07-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| DE69819345T Expired - Lifetime DE69819345T2 (de) | 1997-08-20 | 1998-08-20 | Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung |
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|---|---|
| US (3) | US6335180B1 (enExample) |
| EP (1) | EP1009804B1 (enExample) |
| JP (1) | JP4444493B2 (enExample) |
| AT (1) | ATE253111T1 (enExample) |
| AU (1) | AU742391B2 (enExample) |
| CA (1) | CA2298540A1 (enExample) |
| DE (1) | DE69819345T2 (enExample) |
| WO (1) | WO1999009140A1 (enExample) |
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| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| JP2002503451A (ja) * | 1998-01-22 | 2002-02-05 | ザ・レジェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | カプサイシン受容体をコードする核酸配列 |
| WO1999037765A1 (en) * | 1998-01-27 | 1999-07-29 | Smithkline Beecham Plc | Human vanilloid receptor homologues |
| EP0943683A1 (en) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Human vanilloid receptor homologue Vanilrep1 |
| EP0953638A1 (en) * | 1998-03-11 | 1999-11-03 | Synthelabo | Human vanilloid receptor-like cation channel |
| US6906178B2 (en) | 1998-08-11 | 2005-06-14 | Human Genome Sciences, Inc. | Vanilloid receptor-2 |
| JP2002531069A (ja) * | 1998-11-13 | 2002-09-24 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用 |
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| US6974818B2 (en) | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
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| TWI287010B (en) * | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
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| DE602004021206D1 (de) * | 2003-07-24 | 2009-07-02 | Euro Celtique Sa | Zur Behandlung oder Vorbeugung von Schmerzen geeignete Heteroaryl-Tetrahydropiperidyl-Verbindungen |
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| PT1648880E (pt) * | 2003-08-01 | 2010-04-26 | Euro Celtique Sa | Agentes terapêuticos úteis para o tratamento da dor |
| PL1664041T3 (pl) * | 2003-09-22 | 2008-12-31 | Euro Celtique Sa | Przydatne do leczenia bólu związki fenylowo-karboksyamidowe |
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| US20070159522A1 (en) * | 2004-02-20 | 2007-07-12 | Harmut Neven | Image-based contextual advertisement method and branded barcodes |
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| WO2008057300A2 (en) * | 2006-10-27 | 2008-05-15 | Redpoint Bio Corporation | Trpvi antagonists and uses thereof |
| JP5372913B2 (ja) | 2007-04-27 | 2013-12-18 | パーデュー、ファーマ、リミテッド、パートナーシップ | 疼痛治療に有効な治療薬 |
| ES2571533T3 (es) * | 2007-04-27 | 2016-05-25 | Purdue Pharma Lp | Antagonistas de TRPV1 y usos de los mismos |
| EP2170564A4 (en) | 2007-07-12 | 2015-10-07 | Univ Nebraska | ACTUATING PROCESSES AND SYSTEMS IN ROBOTIC EQUIPMENT |
| US20090076536A1 (en) | 2007-08-15 | 2009-03-19 | Board Of Regents Of The University Of Nebraska | Medical inflation, attachment, and delivery devices and related methods |
| WO2009114143A1 (en) * | 2008-03-12 | 2009-09-17 | Brown University | Treatment and prophylaxis of epilepsy and febrile seizures |
| US8759362B2 (en) * | 2008-10-24 | 2014-06-24 | Purdue Pharma L.P. | Bicycloheteroaryl compounds and their use as TRPV1 ligands |
| US8703962B2 (en) * | 2008-10-24 | 2014-04-22 | Purdue Pharma L.P. | Monocyclic compounds and their use as TRPV1 ligands |
| US8546388B2 (en) * | 2008-10-24 | 2013-10-01 | Purdue Pharma L.P. | Heterocyclic TRPV1 receptor ligands |
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| CN114027986B (zh) | 2015-08-03 | 2024-06-14 | 内布拉斯加大学董事会 | 机器人手术装置系统及相关方法 |
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| CA3036897C (en) | 2016-10-25 | 2021-11-16 | The Procter & Gamble Company | Fibrous structures |
| US10745865B2 (en) | 2016-10-25 | 2020-08-18 | The Procter & Gamble Company | Creped fibrous structures |
| CN115337111B (zh) | 2016-11-22 | 2025-04-25 | 内布拉斯加大学董事会 | 改进的粗定位装置及相关系统和方法 |
| JP7099728B2 (ja) | 2016-11-29 | 2022-07-12 | バーチャル インシジョン コーポレイション | ユーザの存在検出機能を備えたユーザコントローラ、関連システムおよび方法 |
| US10722319B2 (en) | 2016-12-14 | 2020-07-28 | Virtual Incision Corporation | Releasable attachment device for coupling to medical devices and related systems and methods |
| EP3687370B1 (en) | 2017-09-27 | 2024-11-20 | Virtual Incision Corporation | Robotic surgical devices with tracking camera technology and related systems |
| US11013564B2 (en) | 2018-01-05 | 2021-05-25 | Board Of Regents Of The University Of Nebraska | Single-arm robotic device with compact joint design and related systems and methods |
| EP3908171A4 (en) | 2019-01-07 | 2022-09-14 | Virtual Incision Corporation | Robotically assisted surgical system and related devices and methods |
| CN110045108B (zh) * | 2019-05-28 | 2021-10-29 | 江南大学 | 一种基于辣椒碱指标的地沟油酶联免疫检测试剂盒及其检测方法 |
| GB201918103D0 (en) * | 2019-12-10 | 2020-01-22 | Oblique Therapeutics Ab | Epitopes and antibodies |
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| US5074977A (en) | 1987-05-05 | 1991-12-24 | The Washington Technology Center | Digital biosensors and method of using same |
| DE68926118T2 (de) | 1988-08-18 | 1996-08-22 | Australian Membrane And Biotechnology Research Institute Ltd. Commonwealth Scientific And Industrial Research Organization, North Ryde, Neusuedwales | Verbesserungen an der empfindlichkeit und der selektivität von ionenkanalmembranbiosensoren |
| DE69030811T2 (de) | 1989-01-27 | 1997-10-02 | Au Membrane & Biotech Res Inst | Rezeptormembranen und selektive steuerung des ionenflusses durch ionophoren |
| US5491097A (en) | 1989-06-15 | 1996-02-13 | Biocircuits Corporation | Analyte detection with multilayered bioelectronic conductivity sensors |
| US5328847A (en) | 1990-02-20 | 1994-07-12 | Case George D | Thin membrane sensor with biochemical switch |
| US5232684A (en) * | 1990-06-29 | 1993-08-03 | The United States Of America As Represented By The Department Of Health And Human Services | Labelled resiniferatoxin, compositions thereof, and methods for using the same |
| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| WO1999037765A1 (en) | 1998-01-27 | 1999-07-29 | Smithkline Beecham Plc | Human vanilloid receptor homologues |
| EP0943683A1 (en) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Human vanilloid receptor homologue Vanilrep1 |
| EP0953638A1 (en) | 1998-03-11 | 1999-11-03 | Synthelabo | Human vanilloid receptor-like cation channel |
| JP2002531069A (ja) | 1998-11-13 | 2002-09-24 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用 |
| GB9826359D0 (en) * | 1998-12-01 | 1999-01-27 | Glaxo Group Ltd | Novel receptors |
| WO2000063415A1 (en) | 1999-04-15 | 2000-10-26 | Ortho-Mcneil Pharmaceutical, Inc. | Dna encoding the human vanilloid receptor vr1 |
| EP1144628A3 (en) | 1999-11-12 | 2002-02-27 | Abbott Laboratories | Human vanilloid receptor gene |
| AU2001247460A1 (en) | 2000-03-15 | 2001-09-24 | Millennium Pharmaceuticals, Inc. | 18615 and 48003, human ion channels and uses therefor |
| JP3501775B2 (ja) | 2000-05-31 | 2004-03-02 | ファイザー株式会社 | ヒトバニロイド受容体様タンパク質 |
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- 1998-08-20 AU AU91156/98A patent/AU742391B2/en not_active Expired
- 1998-08-20 EP EP98943332A patent/EP1009804B1/en not_active Expired - Lifetime
- 1998-08-20 JP JP2000509807A patent/JP4444493B2/ja not_active Expired - Lifetime
- 1998-08-20 CA CA002298540A patent/CA2298540A1/en not_active Abandoned
- 1998-08-20 AT AT98943332T patent/ATE253111T1/de not_active IP Right Cessation
- 1998-08-20 DE DE69819345T patent/DE69819345T2/de not_active Expired - Lifetime
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1999
- 1999-01-22 US US09/235,451 patent/US6335180B1/en not_active Expired - Lifetime
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2001
- 2001-10-15 US US09/978,303 patent/US6790629B2/en not_active Expired - Lifetime
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2004
- 2004-08-09 US US10/915,017 patent/US7097991B2/en not_active Expired - Lifetime
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| US7097991B2 (en) | 2006-08-29 |
| CA2298540A1 (en) | 1999-02-25 |
| WO1999009140A1 (en) | 1999-02-25 |
| AU9115698A (en) | 1999-03-08 |
| AU742391B2 (en) | 2002-01-03 |
| EP1009804A1 (en) | 2000-06-21 |
| EP1009804B1 (en) | 2003-10-29 |
| DE69819345D1 (de) | 2003-12-04 |
| JP4444493B2 (ja) | 2010-03-31 |
| US20030049728A1 (en) | 2003-03-13 |
| US6335180B1 (en) | 2002-01-01 |
| EP1009804A4 (en) | 2001-05-16 |
| US6790629B2 (en) | 2004-09-14 |
| US20050095650A1 (en) | 2005-05-05 |
| ATE253111T1 (de) | 2003-11-15 |
| JP2001514879A (ja) | 2001-09-18 |
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