ATE253111T1 - Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung - Google Patents
Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendungInfo
- Publication number
- ATE253111T1 ATE253111T1 AT98943332T AT98943332T ATE253111T1 AT E253111 T1 ATE253111 T1 AT E253111T1 AT 98943332 T AT98943332 T AT 98943332T AT 98943332 T AT98943332 T AT 98943332T AT E253111 T1 ATE253111 T1 AT E253111T1
- Authority
- AT
- Austria
- Prior art keywords
- capsaicin receptor
- receptor
- polypeptides
- capsaicin
- related aspects
- Prior art date
Links
- 102000011040 TRPV Cation Channels Human genes 0.000 title abstract 10
- 108010062740 TRPV Cation Channels Proteins 0.000 title abstract 10
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 150000007523 nucleic acids Chemical group 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical class COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 229960002504 capsaicin Drugs 0.000 abstract 1
- 235000017663 capsaicin Nutrition 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91546197A | 1997-08-20 | 1997-08-20 | |
| US7215198P | 1998-01-22 | 1998-01-22 | |
| PCT/US1998/017466 WO1999009140A1 (en) | 1997-08-20 | 1998-08-20 | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE253111T1 true ATE253111T1 (de) | 2003-11-15 |
Family
ID=26753050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98943332T ATE253111T1 (de) | 1997-08-20 | 1998-08-20 | Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6335180B1 (de) |
| EP (1) | EP1009804B1 (de) |
| JP (1) | JP4444493B2 (de) |
| AT (1) | ATE253111T1 (de) |
| AU (1) | AU742391B2 (de) |
| CA (1) | CA2298540A1 (de) |
| DE (1) | DE69819345T2 (de) |
| WO (1) | WO1999009140A1 (de) |
Families Citing this family (97)
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| US6444440B1 (en) | 1997-03-07 | 2002-09-03 | Human Genome Sciences, Inc. | Vanilloid receptor-2 |
| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| CA2309903C (en) * | 1998-01-22 | 2012-03-27 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor |
| EP1066381A1 (de) * | 1998-01-27 | 2001-01-10 | Smithkline Beecham Plc | Homologe des menschlichen vanilloidrezeptors |
| EP0943683A1 (de) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Menschliches Vanilloid Rezeptorhomolog Vanilrep1 |
| EP0953638A1 (de) * | 1998-03-11 | 1999-11-03 | Synthelabo | Dem menschlichen Vanilloid Rezeptor ähnlicher Kationenkanal |
| US6906178B2 (en) | 1998-08-11 | 2005-06-14 | Human Genome Sciences, Inc. | Vanilloid receptor-2 |
| CA2348479A1 (en) * | 1998-11-13 | 2000-05-25 | Millennium Pharmaceuticals, Inc. | Novel members of the capsaicin/vanilloid receptor family of proteins and uses thereof |
| US7063951B1 (en) | 1998-11-13 | 2006-06-20 | Millennium Pharmaceuticals, Inc. | Members of the capsaicin/vanilloid receptor family of proteins and uses thereof |
| GB9826359D0 (en) * | 1998-12-01 | 1999-01-27 | Glaxo Group Ltd | Novel receptors |
| GB9827016D0 (en) | 1998-12-08 | 1999-02-03 | Merck Sharp & Dohme | Receptor protein |
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| WO2002044210A2 (en) * | 2000-12-01 | 2002-06-06 | Bristol-Myers Squibb Company | Novel human nucleic acid molecules and polypeptides encoding a novel human ion channel expressed in spinal cord and brain |
| US20030171275A1 (en) * | 2000-12-20 | 2003-09-11 | Baughn Mariah R. | Transporters and ion channels |
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| AU2002318168B2 (en) | 2002-02-25 | 2007-12-13 | Vaxiion Therapeutics, Llc | Minicell compositions and methods |
| US6974818B2 (en) * | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
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| WO2003102156A2 (en) * | 2002-05-31 | 2003-12-11 | Sloan-Kettering Institute For Cancer Research | Heterologous stimulus-gated ion channels and methods of using same |
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| DE602004020994D1 (de) * | 2003-07-24 | 2009-06-18 | Euro Celtique Sa | Piperidinverbindungen und pharmazeutische zusammensetzungen, die diese enthalten |
| PL1867644T3 (pl) | 2003-07-24 | 2009-10-30 | Euro Celtique Sa | Związki heteroarylo-tetrahydropiperydylowe przydatne w leczeniu lub zapobieganiu bólu |
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| WO2009014917A2 (en) | 2007-07-12 | 2009-01-29 | Board Of Regents Of The University Of Nebraska | Methods and systems of actuation in robotic devices |
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| WO2009114143A1 (en) * | 2008-03-12 | 2009-09-17 | Brown University | Treatment and prophylaxis of epilepsy and febrile seizures |
| US8703962B2 (en) * | 2008-10-24 | 2014-04-22 | Purdue Pharma L.P. | Monocyclic compounds and their use as TRPV1 ligands |
| US8759362B2 (en) * | 2008-10-24 | 2014-06-24 | Purdue Pharma L.P. | Bicycloheteroaryl compounds and their use as TRPV1 ligands |
| US8546388B2 (en) * | 2008-10-24 | 2013-10-01 | Purdue Pharma L.P. | Heterocyclic TRPV1 receptor ligands |
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| RU2621708C2 (ru) | 2011-06-22 | 2017-06-07 | ПУРДЬЮ ФАРМА Эл. Пи. | Антагонисты trpv1, включающие дигидроксигруппу в качестве заместителя, и их применение |
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| CA3098065C (en) | 2012-01-10 | 2023-10-31 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices for surgical access and insertion |
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| US9010214B2 (en) | 2012-06-22 | 2015-04-21 | Board Of Regents Of The University Of Nebraska | Local control robotic surgical devices and related methods |
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| WO2014160086A2 (en) | 2013-03-14 | 2014-10-02 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to robotic surgical devices, end effectors, and controllers |
| EP4628042A3 (de) | 2013-03-15 | 2025-12-31 | Virtual Incision Corporation | Robotische chirurgische vorrichtungen und systeme |
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| CN106537149A (zh) | 2014-04-01 | 2017-03-22 | 宝洁公司 | 用于筛选色氨酸通道的方法 |
| JP6710199B2 (ja) | 2014-09-12 | 2020-06-17 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | クイックリリースエンドエフェクターおよび関連するシステムおよび方法 |
| JP6608928B2 (ja) | 2014-11-11 | 2019-11-20 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | 小型の関節デザインを備えるロボットデバイスおよび関連するシステムおよび方法 |
| EP3331453B1 (de) | 2015-08-03 | 2025-05-14 | Virtual Incision Corporation | Robotische chirurgische vorrichtungen und systeme |
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| WO2018081189A1 (en) | 2016-10-25 | 2018-05-03 | The Procter & Gamble Company | Fibrous structures |
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| US10675110B2 (en) | 2016-11-29 | 2020-06-09 | Virtual Incision Corporation | User controller with user presence detection and related systems and methods |
| US10722319B2 (en) | 2016-12-14 | 2020-07-28 | Virtual Incision Corporation | Releasable attachment device for coupling to medical devices and related systems and methods |
| CN111417333B (zh) | 2017-09-27 | 2023-08-29 | 虚拟切割有限公司 | 具有跟踪相机技术的机器人手术设备及相关系统和方法 |
| CN111770816B (zh) | 2018-01-05 | 2023-11-03 | 内布拉斯加大学董事会 | 具有紧凑型关节设计的单臂机器人装置及相关系统和方法 |
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| CN110045108B (zh) * | 2019-05-28 | 2021-10-29 | 江南大学 | 一种基于辣椒碱指标的地沟油酶联免疫检测试剂盒及其检测方法 |
| GB201918103D0 (en) * | 2019-12-10 | 2020-01-22 | Oblique Therapeutics Ab | Epitopes and antibodies |
| CN115843233A (zh) | 2020-07-06 | 2023-03-24 | 虚拟切割有限公司 | 手术机器人定位系统及相关装置和方法 |
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| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| EP1066381A1 (de) | 1998-01-27 | 2001-01-10 | Smithkline Beecham Plc | Homologe des menschlichen vanilloidrezeptors |
| EP0943683A1 (de) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Menschliches Vanilloid Rezeptorhomolog Vanilrep1 |
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1998
- 1998-08-20 WO PCT/US1998/017466 patent/WO1999009140A1/en not_active Ceased
- 1998-08-20 DE DE69819345T patent/DE69819345T2/de not_active Expired - Lifetime
- 1998-08-20 AU AU91156/98A patent/AU742391B2/en not_active Expired
- 1998-08-20 AT AT98943332T patent/ATE253111T1/de not_active IP Right Cessation
- 1998-08-20 JP JP2000509807A patent/JP4444493B2/ja not_active Expired - Lifetime
- 1998-08-20 CA CA002298540A patent/CA2298540A1/en not_active Abandoned
- 1998-08-20 EP EP98943332A patent/EP1009804B1/de not_active Expired - Lifetime
-
1999
- 1999-01-22 US US09/235,451 patent/US6335180B1/en not_active Expired - Lifetime
-
2001
- 2001-10-15 US US09/978,303 patent/US6790629B2/en not_active Expired - Lifetime
-
2004
- 2004-08-09 US US10/915,017 patent/US7097991B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69819345T2 (de) | 2004-07-15 |
| WO1999009140A1 (en) | 1999-02-25 |
| US7097991B2 (en) | 2006-08-29 |
| AU742391B2 (en) | 2002-01-03 |
| US20030049728A1 (en) | 2003-03-13 |
| JP2001514879A (ja) | 2001-09-18 |
| EP1009804A1 (de) | 2000-06-21 |
| US20050095650A1 (en) | 2005-05-05 |
| US6790629B2 (en) | 2004-09-14 |
| EP1009804A4 (de) | 2001-05-16 |
| AU9115698A (en) | 1999-03-08 |
| US6335180B1 (en) | 2002-01-01 |
| DE69819345D1 (de) | 2003-12-04 |
| CA2298540A1 (en) | 1999-02-25 |
| EP1009804B1 (de) | 2003-10-29 |
| JP4444493B2 (ja) | 2010-03-31 |
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