ATE189607T1 - Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung - Google Patents

Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung

Info

Publication number
ATE189607T1
ATE189607T1 AT95907215T AT95907215T ATE189607T1 AT E189607 T1 ATE189607 T1 AT E189607T1 AT 95907215 T AT95907215 T AT 95907215T AT 95907215 T AT95907215 T AT 95907215T AT E189607 T1 ATE189607 T1 AT E189607T1
Authority
AT
Austria
Prior art keywords
human
receptor
nucleic acid
acid molecule
encoding
Prior art date
Application number
AT95907215T
Other languages
English (en)
Inventor
Jonathan A Bard
Mary W Walker
Theresa Branchek
Richard L Weinshank
Original Assignee
Synaptic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22644257&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE189607(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synaptic Pharma Corp filed Critical Synaptic Pharma Corp
Application granted granted Critical
Publication of ATE189607T1 publication Critical patent/ATE189607T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
AT95907215T 1993-12-28 1994-12-28 Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung ATE189607T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/176,412 US5516653A (en) 1993-12-28 1993-12-28 DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
PCT/US1994/014436 WO1995017906A1 (en) 1993-12-28 1994-12-28 Dna encoding a human neuropeptide y/peptide yy/pancreatic polypeptide receptor (y4) and uses thereof

Publications (1)

Publication Number Publication Date
ATE189607T1 true ATE189607T1 (de) 2000-02-15

Family

ID=22644257

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95907215T ATE189607T1 (de) 1993-12-28 1994-12-28 Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung

Country Status (11)

Country Link
US (4) US5516653A (de)
EP (1) EP0746332B2 (de)
JP (1) JP4216326B2 (de)
AT (1) ATE189607T1 (de)
AU (1) AU702438B2 (de)
CA (1) CA2156272C (de)
DE (2) DE746332T1 (de)
DK (1) DK0746332T4 (de)
ES (1) ES2097717T5 (de)
GR (1) GR970300026T1 (de)
WO (1) WO1995017906A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516653A (en) 1993-12-28 1996-05-14 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
US5545549A (en) * 1994-02-03 1996-08-13 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
JPH10508486A (ja) * 1994-11-07 1998-08-25 メルク エンド カンパニー インコーポレーテッド 修飾神経ペプチドyレセプター
US5602024A (en) * 1994-12-02 1997-02-11 Synaptic Pharmaceutical Corporation DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
US5989920A (en) 1994-12-02 1999-11-23 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
US5965392A (en) 1996-04-08 1999-10-12 Bayer Corporation Neuropeptide Y receptor Y5 and nucleic acid sequences
US5919901A (en) * 1996-04-08 1999-07-06 Bayer Corporation Neuropeptide Y receptor Y5 and nucleic acid sequences
US5908830A (en) * 1996-10-31 1999-06-01 Merck & Co., Inc. Combination therapy for the treatment of diabetes and obesity
US6713265B1 (en) 1997-06-04 2004-03-30 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
US5916869A (en) * 1997-06-13 1999-06-29 North Carolina State University Method of treating birds in ovo
GB2344050A (en) * 1998-11-26 2000-05-31 Ferring Bv Agents useful in the treatment of reproductive disorders.
US7745216B2 (en) 1999-02-10 2010-06-29 Curis, Inc. Methods and reagents for treating glucose metabolic disorders
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
AU6727900A (en) * 1999-08-27 2001-03-26 Takeda Chemical Industries Ltd. Novel g protein-coupled receptor protein and dna thereof
WO2001053477A1 (en) * 2000-01-20 2001-07-26 Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of neuropeptide y activity
ATE386821T1 (de) 2000-10-23 2008-03-15 Gen Probe Inc Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2)
EP1362926A1 (de) * 2002-05-15 2003-11-19 Integragen Humanes fettleibigkeit Suszeptibilitätsgen und deren Verwendungen
EP1403380A1 (de) * 2002-09-27 2004-03-31 Integragen Humanes fettleibigkeit Suszeptibilitätsgen und deren Verwendungen
EP1997913A1 (de) * 2002-05-15 2008-12-03 Integragen Menschliches Adipositas-Suszeptibilitäsgen und Verwendungen davon
EP1583549A4 (de) * 2003-01-17 2006-10-04 Sod Conseils Rech Applic Yy-peptid-analoga
WO2004087882A2 (en) * 2003-03-26 2004-10-14 Washington University Neuregulin protein regulation of synaptic proteins
EP1688494A4 (de) * 2003-10-30 2007-08-08 Banyu Pharma Co Ltd Npy-y4-rezeptor aus affe und verfahren zur beurteilung einer verbindung
US20070270339A1 (en) * 2004-04-23 2007-11-22 Serono, Inc. Use of GPCR54 Ligands for the Treatment of Infertility
CA2565801A1 (en) * 2004-05-28 2005-12-15 Applied Research Systems Ars Holding N.V. Use of il-17 in the treatment of fertility-related disorders
PA8660701A1 (es) * 2005-02-04 2006-09-22 Pfizer Prod Inc Agonistas de pyy y sus usos
WO2006091506A2 (en) * 2005-02-24 2006-08-31 Bayer Pharmaceuticals Corporation Neuropeptide y4 receptor agonists
EA200800874A1 (ru) * 2005-09-21 2008-08-29 7ТиЭм ФАРМА А/С Рецепторные агонисты, селективные к y4 рецептору, для терапевтического воздействия
EA200800875A1 (ru) 2005-09-21 2008-08-29 7ТиЭм ФАРМА А/С Рецепторные агонисты, селективные к y2 рецептору, для терапевтического воздействия
US20070197445A1 (en) 2006-01-18 2007-08-23 University Of Cincinnati Compounds for control of appetite
EP1990427A4 (de) 2006-02-24 2009-04-29 Banyu Pharma Co Ltd Npy y4-agonist als therapeutikum gegen eine von einer fehlfunktion des darmtrakts begleitete krankheit
WO2010096188A2 (en) * 2009-02-20 2010-08-26 Ipsen Pharma S.A.S Analogues of neuropeptide y having proline substitution at position 34

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US4839343A (en) * 1987-03-13 1989-06-13 Debiopharm, S.A. Preparation containing hexatriacontapeptides and methods of use
US5026685A (en) * 1988-07-15 1991-06-25 The Salk Institute For Biological Studies NPY peptide analogs
US5328899A (en) * 1988-07-15 1994-07-12 The Salk Institute For Biological Studies NPY peptide analogs
GB8818020D0 (en) * 1988-07-28 1988-09-01 Ici Plc Method for amplification of nucleotide sequences
ZA896376B (en) * 1988-08-26 1990-05-30 Merrell Dow Pharma Neuropeptide y agonists
ZA896374B (en) * 1988-08-26 1990-05-30 Merrell Dow Pharma Neuropeptide y antagonists
US5053337A (en) * 1989-10-30 1991-10-01 Neurogenetic Corporation DNA encoding an α2B -adrenergic receptor
DE59006842D1 (de) * 1990-03-30 1994-09-22 Heumann Pharma Gmbh & Co Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels mit NPY-antagonistischer Wirkung.
SE9002278L (sv) * 1990-06-28 1991-12-29 Perstorp Ab Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel
JPH0463594A (ja) * 1990-07-03 1992-02-28 Tanpaku Kogaku Kenkyusho:Kk 成長ホルモンレセプターのホルモン結合領域蛋白の製造法
WO1993009227A1 (en) * 1991-11-06 1993-05-13 Garvan Institute Of Medical Research Human neuropeptide y-y1 receptor
WO1993024515A1 (en) * 1992-05-29 1993-12-09 Cornell Research Foundation, Inc. Human neuropeptide y/peptide yy receptor of the y1-type and antisense oligonucleotides thereto which inhibit vasoconstriction
GB9213215D0 (en) * 1992-06-20 1992-08-05 Wellcome Found Peptides
JPH06116284A (ja) * 1992-10-02 1994-04-26 Yamanouchi Pharmaceut Co Ltd 新規ペプチド
FR2701480B1 (fr) * 1993-02-15 1995-05-24 Sanofi Elf Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant.
EP0692971A4 (de) * 1993-03-29 1997-11-12 Univ Cincinnati Peptid yy-analogen und verwendungen dafür
JPH11501281A (ja) * 1993-06-18 1999-02-02 ユニバーシティ オブ シンシナティ 神経ペプチドyアンタゴニスト及びアゴニスト
US5516653A (en) 1993-12-28 1996-05-14 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
CA2134428A1 (en) * 1994-10-26 1996-04-27 Albert Tseng Neuropeptide y y2 agonist peptides
JPH10508486A (ja) * 1994-11-07 1998-08-25 メルク エンド カンパニー インコーポレーテッド 修飾神経ペプチドyレセプター
US5602024A (en) * 1994-12-02 1997-02-11 Synaptic Pharmaceutical Corporation DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
US5621079A (en) * 1995-02-03 1997-04-15 Merck & Co., Inc. Neuropeptide Y receptor
AUPN646795A0 (en) * 1995-11-09 1995-11-30 Garvan Institute Of Medical Research Neuropeptide Y-Y5 receptor
US5965392A (en) * 1996-04-08 1999-10-12 Bayer Corporation Neuropeptide Y receptor Y5 and nucleic acid sequences
US6355478B1 (en) * 1996-06-17 2002-03-12 Eli Lilly And Company Rhesus monkey neuropeptide Y Y2 receptor

Also Published As

Publication number Publication date
AU1551895A (en) 1995-07-17
GR970300026T1 (en) 1997-09-30
AU702438B2 (en) 1999-02-18
US6913892B1 (en) 2005-07-05
DK0746332T3 (da) 2000-06-13
WO1995017906A1 (en) 1995-07-06
ES2097717T1 (es) 1997-04-16
ES2097717T5 (es) 2010-10-18
EP0746332B1 (de) 2000-02-09
US5958709A (en) 1999-09-28
EP0746332A4 (de) 1997-02-26
DE69423007T2 (de) 2000-10-19
DK0746332T4 (da) 2010-08-16
EP0746332B2 (de) 2010-05-19
JPH09511127A (ja) 1997-11-11
CA2156272C (en) 2009-09-15
DE69423007T3 (de) 2011-02-10
ES2097717T3 (es) 2000-06-16
US5976814A (en) 1999-11-02
DE746332T1 (de) 1997-04-10
JP4216326B2 (ja) 2009-01-28
DE69423007D1 (de) 2000-03-16
CA2156272A1 (en) 1995-07-06
EP0746332A1 (de) 1996-12-11
US5516653A (en) 1996-05-14

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