DE69727332D1 - Zubereitungen enthaltend Kollagen, Vitamin D3 und Kalzium zur Verstärkung des Knochens - Google Patents
Zubereitungen enthaltend Kollagen, Vitamin D3 und Kalzium zur Verstärkung des KnochensInfo
- Publication number
- DE69727332D1 DE69727332D1 DE69727332T DE69727332T DE69727332D1 DE 69727332 D1 DE69727332 D1 DE 69727332D1 DE 69727332 T DE69727332 T DE 69727332T DE 69727332 T DE69727332 T DE 69727332T DE 69727332 D1 DE69727332 D1 DE 69727332D1
- Authority
- DE
- Germany
- Prior art keywords
- vitamin
- strengthen
- bone
- calcium
- preparations containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title 1
- 102000008186 Collagen Human genes 0.000 title 1
- 108010035532 Collagen Proteins 0.000 title 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
- 229910052791 calcium Inorganic materials 0.000 title 1
- 239000011575 calcium Substances 0.000 title 1
- 229920001436 collagen Polymers 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title 1
- 235000005282 vitamin D3 Nutrition 0.000 title 1
- 239000011647 vitamin D3 Substances 0.000 title 1
- 229940021056 vitamin d3 Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
- A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
- A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
- A21D2/24—Organic nitrogen compounds
- A21D2/26—Proteins
- A21D2/261—Animal proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
- A23C19/068—Particular types of cheese
- A23C19/08—Process cheese preparations; Making thereof, e.g. melting, emulsifying, sterilizing
- A23C19/082—Adding substances to the curd before or during melting; Melting salts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
- A23C9/1315—Non-milk proteins or fats; Seeds, pulses, cereals or soja; Fatty acids, phospholipids, mono- or diglycerides or derivatives therefrom; Egg products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/10—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from hair, feathers, horn, skins, leather, bones, or the like
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
- A23K50/42—Dry feed
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/66—Proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/256—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/275—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
- A23L29/281—Proteins, e.g. gelatin or collagen
- A23L29/284—Gelatin; Collagen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9905996 | 1996-03-28 | ||
JP09905996A JP4609807B2 (ja) | 1996-03-28 | 1996-03-28 | 骨強化用医薬、飲食品及び飼料 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69727332D1 true DE69727332D1 (de) | 2004-03-04 |
DE69727332T2 DE69727332T2 (de) | 2004-11-18 |
Family
ID=14237144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1997627332 Expired - Lifetime DE69727332T2 (de) | 1996-03-28 | 1997-03-27 | Zubereitungen enthaltend Kollagen, Vitamin D3 und Kalzium zur Verstärkung des Knochens |
Country Status (4)
Country | Link |
---|---|
US (2) | US6344437B1 (de) |
EP (1) | EP0798001B1 (de) |
JP (1) | JP4609807B2 (de) |
DE (1) | DE69727332T2 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1112192A (ja) * | 1997-06-18 | 1999-01-19 | Zenyaku Kogyo Kk | 骨粗鬆症予防・治療剤 |
JP3881453B2 (ja) * | 1998-05-14 | 2007-02-14 | 新田ゼラチン株式会社 | カルシウム吸収促進剤およびその製造方法 |
JP2000184860A (ja) * | 1998-12-22 | 2000-07-04 | Goshu Shoji Kk | コラーゲン含有食品の製造方法 |
JP2001026753A (ja) * | 1999-07-14 | 2001-01-30 | Sunstar Inc | 高血圧症予防又は治療用組成物 |
JP2001031586A (ja) * | 1999-07-14 | 2001-02-06 | Sunstar Inc | 動脈硬化症及び動脈硬化症に起因する疾患の予防又は治療組成物 |
JP3802721B2 (ja) * | 1999-11-05 | 2006-07-26 | 株式会社ファンケル | 生体コラーゲン合成促進剤 |
JP2001158736A (ja) * | 1999-11-30 | 2001-06-12 | Snow Brand Milk Prod Co Ltd | 骨関節疾患の予防及び改善剤 |
JP3492970B2 (ja) * | 1999-12-28 | 2004-02-03 | 和子 三浦 | コラーゲンのゼリー状加工食品及びその製造方法 |
JP2002255847A (ja) * | 2001-02-26 | 2002-09-11 | Miyagi Kagaku Kogyo Kk | コラーゲン産生促進剤、それを含む機能性食品および医薬品 |
US20030049304A1 (en) * | 2001-08-29 | 2003-03-13 | Somani Jitendra Krishan | Quiescently frozen ice products |
US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
JP2003137807A (ja) * | 2001-11-01 | 2003-05-14 | Miyagi Kagaku Kogyo Kk | コラーゲン産生促進剤、それを含む化粧品、食品および医薬品ならびに皮膚疾患の予防または改善用外用剤 |
US20050095228A1 (en) | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
CN1630526B (zh) | 2001-12-07 | 2010-05-05 | 马克罗珀尔生物外科公司 | 用加工的脂肪抽吸细胞来治疗患者的系统和方法 |
US7585670B2 (en) | 2001-12-07 | 2009-09-08 | Cytori Therapeutics, Inc. | Automated methods for isolating and using clinically safe adipose derived regenerative cells |
US20050048035A1 (en) | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
US9597395B2 (en) | 2001-12-07 | 2017-03-21 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
US6824941B2 (en) * | 2002-05-08 | 2004-11-30 | Eastman Kodak Company | Photographic element containing acid processed gelatin |
JP4766818B2 (ja) * | 2002-07-24 | 2011-09-07 | 隆文 小濱 | 妊娠時に特異的な腰痛、股関節痛及び鼠径部痛の改善・治療剤 |
JP2005047844A (ja) * | 2003-07-28 | 2005-02-24 | Hiroshi Yamazaki | 生物由来高分子物質の分解物、これを含む食品、化粧品、及び医薬品並びにそれらの製造方法 |
DE10339180A1 (de) * | 2003-08-21 | 2005-03-24 | Deutsche Gelatine-Fabriken Stoess Ag | Kollagenhydrolysat |
WO2005104916A1 (en) * | 2004-04-16 | 2005-11-10 | Urnex Brands, Inc. | System and method for cleaning a grinding machine |
JP4523339B2 (ja) * | 2004-06-04 | 2010-08-11 | 新田ゼラチン株式会社 | 骨靭性向上用素材 |
JPWO2007066654A1 (ja) * | 2005-12-09 | 2009-05-21 | 日本水産株式会社 | 魚骨ペーストとその製造方法及びその用途 |
US9011930B2 (en) * | 2006-05-01 | 2015-04-21 | Zycal Bioceuticals Healthcare Company, Inc. | Nutritional supplement and use thereof |
WO2008059927A1 (fr) | 2006-11-15 | 2008-05-22 | Meiji Seika Kaisha, Ltd. | Composition de peptide de collagène et aliment ou boisson la contenant |
JP2008231065A (ja) * | 2007-03-23 | 2008-10-02 | Chisso Corp | 骨代謝改善剤 |
US20080311059A1 (en) * | 2007-06-15 | 2008-12-18 | National Applied Research Laboratories | Composition for skin care and method for the same |
US20090162490A1 (en) * | 2007-12-20 | 2009-06-25 | Tropicana Products, Inc. | Calcium-fortified beverages and method of making thereof |
WO2010021993A1 (en) | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
SG10201401809RA (en) | 2009-04-28 | 2014-06-27 | Meiji Co Ltd | Collagen Peptide Composition Having Good Blood Transfer Properties, And Food And Drink Containing Same |
BRPI1009981B1 (pt) | 2009-05-01 | 2019-12-31 | Bimini Tech Llc | sistemas, métodos e composições para otimizar os enxertos enriquecidos de tecido e célula |
JP6194304B2 (ja) * | 2012-03-13 | 2017-09-06 | 株式会社明治 | コラーゲンを配合した発酵乳及びその製造方法 |
WO2013137382A1 (ja) * | 2012-03-15 | 2013-09-19 | 協和発酵バイオ株式会社 | 骨代謝改善剤 |
DE102012009946A1 (de) | 2012-05-18 | 2015-08-13 | Dogsli Gmbh | Futtermischung |
WO2014030514A1 (ja) * | 2012-08-24 | 2014-02-27 | 国立大学法人徳島大学 | 筋委縮抑制剤 |
DE102012110612A1 (de) | 2012-11-06 | 2014-05-08 | Gelita Ag | Kollagenhydrolysat und dessen Verwendung |
JP5873422B2 (ja) * | 2012-12-14 | 2016-03-01 | 森永乳業株式会社 | 撹拌型発酵乳の製造方法 |
ES2791448T3 (es) | 2013-01-23 | 2020-11-04 | Bottled Science Ltd | Composición de bebida para mejorar la piel |
JP6422993B2 (ja) * | 2014-11-11 | 2018-11-14 | 株式会社ニッピ | 免疫賦活化剤、細胞性免疫賦活化剤およびt細胞数増加剤 |
JP2016204323A (ja) * | 2015-04-27 | 2016-12-08 | フジ日本精糖株式会社 | 骨形成促進剤 |
CN110944519A (zh) * | 2017-08-10 | 2020-03-31 | 雀巢产品有限公司 | 饮料 |
CN109007473A (zh) * | 2018-07-25 | 2018-12-18 | 广州市雅禾生物科技有限公司 | 一种含牛骨水解胶原蛋白的功能饮料及其制备方法 |
JP2021166501A (ja) * | 2020-04-08 | 2021-10-21 | 竹内酒造株式会社 | サプリメント |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1227534A (de) | 1967-08-31 | 1971-04-07 | ||
US4335120A (en) * | 1979-03-21 | 1982-06-15 | Hoffmann-La Roche Inc. | Administration of biologically active vitamin D3 and vitamin D2 materials |
US4294753A (en) * | 1980-08-04 | 1981-10-13 | The Regents Of The University Of California | Bone morphogenetic protein process |
US4698326A (en) * | 1985-12-20 | 1987-10-06 | Regents Of The University Of Minnesota | Composition and method for osseous repair |
CA1302880C (en) | 1986-07-25 | 1992-06-09 | Peter Koepff | Agents for the treatment of arthroses |
US5114627A (en) * | 1986-10-16 | 1992-05-19 | Cbs Lens | Method for producing a collagen hydrogel |
US5057502A (en) * | 1987-06-02 | 1991-10-15 | Walsh William E | Composition and topical and systemic treatments of conditions caused by heavy, oily or greasy secretions |
GB8812993D0 (en) | 1988-06-01 | 1988-07-06 | Natural Resources Mfg Ltd | Improvements in/relating to production of protein products |
US5043170A (en) * | 1989-02-14 | 1991-08-27 | Hoffmann-La Roche Inc. | Animal feed composition containing a vitamin D metabolite |
US5002760A (en) * | 1989-10-02 | 1991-03-26 | Katzev Phillip K | Retinol skin care composition |
US5208219A (en) * | 1991-02-14 | 1993-05-04 | Celtrix Pharmaceuticals Inc. | Method for inducing bone growth |
CN1045719C (zh) | 1993-04-10 | 1999-10-20 | 北京市西城区华新生化技术研究所 | 口服接骨和治骨质疏松液 |
WO1996005851A1 (de) | 1994-08-23 | 1996-02-29 | Dgf Stoess Ag | Verwendung von geschmacksneutralem, hydrolysiertem kollagen und mittel enthaltend dasselbe |
JP3112637B2 (ja) * | 1994-09-30 | 2000-11-27 | 雪印乳業株式会社 | 骨強化剤 |
NL1009164C1 (nl) * | 1998-05-14 | 1999-11-16 | Innoessentials Int Bv | Kleminrichting. |
-
1996
- 1996-03-28 JP JP09905996A patent/JP4609807B2/ja not_active Expired - Fee Related
-
1997
- 1997-03-17 US US08/819,110 patent/US6344437B1/en not_active Expired - Lifetime
- 1997-03-27 EP EP97105286A patent/EP0798001B1/de not_active Expired - Lifetime
- 1997-03-27 DE DE1997627332 patent/DE69727332T2/de not_active Expired - Lifetime
-
2002
- 2002-02-04 US US10/067,527 patent/US20020183261A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0798001A2 (de) | 1997-10-01 |
JP4609807B2 (ja) | 2011-01-12 |
DE69727332T2 (de) | 2004-11-18 |
EP0798001A3 (de) | 1999-02-17 |
US20020183261A1 (en) | 2002-12-05 |
JPH09255588A (ja) | 1997-09-30 |
EP0798001B1 (de) | 2004-01-28 |
US6344437B1 (en) | 2002-02-05 |
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