DE69716602D1 - Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwenung als pharmazeutischemetallchelatoren - Google Patents

Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwenung als pharmazeutischemetallchelatoren

Info

Publication number
DE69716602D1
DE69716602D1 DE69716602T DE69716602T DE69716602D1 DE 69716602 D1 DE69716602 D1 DE 69716602D1 DE 69716602 T DE69716602 T DE 69716602T DE 69716602 T DE69716602 T DE 69716602T DE 69716602 D1 DE69716602 D1 DE 69716602D1
Authority
DE
Germany
Prior art keywords
triazoles
diphenyl
substituted
metal chelators
pharmaceutical metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69716602T
Other languages
English (en)
Other versions
DE69716602T2 (de
DE122007000020I1 (de
Inventor
Rene Lattmann
Pierre Acklin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4214048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69716602(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Priority to DE122007000020C priority Critical patent/DE122007000020I2/de
Publication of DE69716602D1 publication Critical patent/DE69716602D1/de
Application granted granted Critical
Publication of DE69716602T2 publication Critical patent/DE69716602T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69716602T 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwenung als pharmazeutischemetallchelatoren Expired - Lifetime DE69716602T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE122007000020C DE122007000020I2 (de) 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwendung als pharmazeutische metallchelatoren

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH159396 1996-06-25
PCT/EP1997/003315 WO1997049395A1 (en) 1996-06-25 1997-06-24 Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators

Publications (2)

Publication Number Publication Date
DE69716602D1 true DE69716602D1 (de) 2002-11-28
DE69716602T2 DE69716602T2 (de) 2003-06-26

Family

ID=4214048

Family Applications (3)

Application Number Title Priority Date Filing Date
DE122007000020C Active DE122007000020I2 (de) 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwendung als pharmazeutische metallchelatoren
DE69716602T Expired - Lifetime DE69716602T2 (de) 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwenung als pharmazeutischemetallchelatoren
DE1997616602 Pending DE122007000020I1 (de) 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-Triazole und ihreVerwenung als Pharmazeutischemetallchelatoren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE122007000020C Active DE122007000020I2 (de) 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-triazole und ihre verwendung als pharmazeutische metallchelatoren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1997616602 Pending DE122007000020I1 (de) 1996-06-25 1997-06-24 Substituierte 3,5-diphenyl-1,2,4-Triazole und ihreVerwenung als Pharmazeutischemetallchelatoren

Country Status (37)

Country Link
US (3) US6465504B1 (de)
EP (1) EP0914118B1 (de)
JP (1) JP3541042B2 (de)
KR (1) KR100616378B1 (de)
CN (1) CN1146415C (de)
AP (1) AP1127A (de)
AR (1) AR007479A1 (de)
AT (1) ATE226435T1 (de)
AU (1) AU718037B2 (de)
BG (1) BG64248B1 (de)
BR (1) BR9709973A (de)
CA (1) CA2255951C (de)
CY (2) CY2429B1 (de)
CZ (1) CZ291470B6 (de)
DE (3) DE122007000020I2 (de)
DK (1) DK0914118T3 (de)
ES (1) ES2187785T3 (de)
FR (1) FR06C0049I2 (de)
GE (1) GEP20084355B (de)
HK (1) HK1020530A1 (de)
HU (1) HU226232B1 (de)
IL (1) IL127212A0 (de)
LT (1) LTC0914118I2 (de)
LU (1) LU91291I2 (de)
MY (1) MY129541A (de)
NL (1) NL300248I2 (de)
NO (3) NO317180B1 (de)
NZ (1) NZ333308A (de)
OA (1) OA10946A (de)
PL (1) PL194758B1 (de)
PT (1) PT914118E (de)
RU (1) RU2208010C2 (de)
SI (1) SI0914118T1 (de)
SK (1) SK284319B6 (de)
TR (1) TR199802693T2 (de)
TW (1) TW533205B (de)
WO (1) WO1997049395A1 (de)

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CN114276305B (zh) * 2021-12-28 2023-11-17 中山大学 一种三取代苯基-1,2,4-三氮唑衍生物及其制备和治疗神经元损伤的应用
CN114478410B (zh) * 2022-03-31 2022-11-29 中山大学 一种二取代苯基-1,2,4-三氮唑衍生物及其制备和应用
CN114591254B (zh) * 2022-03-31 2023-10-13 中山大学 一种3,5-二取代苯基-1,2,4-三氮唑衍生物及其制备方法和应用

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