DE69531350D1 - Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze - Google Patents

Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze

Info

Publication number
DE69531350D1
DE69531350D1 DE69531350T DE69531350T DE69531350D1 DE 69531350 D1 DE69531350 D1 DE 69531350D1 DE 69531350 T DE69531350 T DE 69531350T DE 69531350 T DE69531350 T DE 69531350T DE 69531350 D1 DE69531350 D1 DE 69531350D1
Authority
DE
Germany
Prior art keywords
group
naphthyridone
substituted
hydrogen atom
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69531350T
Other languages
English (en)
Other versions
DE69531350T2 (de
Inventor
Yozo Todo
Kazuya Hayashi
Masahiro Takahata
Yasuo Watanabe
Hirokazu Narita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of DE69531350D1 publication Critical patent/DE69531350D1/de
Application granted granted Critical
Publication of DE69531350T2 publication Critical patent/DE69531350T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22Tin compounds
    • C07F7/2208Compounds having tin linked only to carbon, hydrogen and/or halogen
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69531350T 1994-08-12 1995-08-04 Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze Expired - Lifetime DE69531350T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21208394 1994-08-12
JP21208394 1994-08-12
PCT/JP1995/001551 WO1996005192A1 (fr) 1994-08-12 1995-08-04 Derive du nouvel acide quinolone- ou naphthyridonecarboxylique ou son sel

Publications (2)

Publication Number Publication Date
DE69531350D1 true DE69531350D1 (de) 2003-08-28
DE69531350T2 DE69531350T2 (de) 2004-05-27

Family

ID=16616594

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69531350T Expired - Lifetime DE69531350T2 (de) 1994-08-12 1995-08-04 Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze

Country Status (17)

Country Link
US (1) US5935952A (de)
EP (1) EP0775702B1 (de)
KR (1) KR100371723B1 (de)
CN (1) CN1070191C (de)
AT (1) ATE245638T1 (de)
AU (1) AU692583B2 (de)
CA (1) CA2196271C (de)
DE (1) DE69531350T2 (de)
DK (1) DK0775702T3 (de)
ES (1) ES2203644T3 (de)
FI (1) FI113652B (de)
HU (1) HU228062B1 (de)
IL (1) IL114875A (de)
NO (1) NO312032B1 (de)
NZ (1) NZ290946A (de)
WO (1) WO1996005192A1 (de)
ZA (1) ZA956713B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011046A (en) * 1995-08-21 2000-01-04 Takeda Chemical Industries, Ltd. Quinone compound, its production and use as antioxidant
CA2242242C (en) * 1996-02-09 2001-08-07 Toyama Chemical Co., Ltd. Quinolonecarboxylic acid derivatives or salts thereof
WO1999007682A1 (fr) * 1997-08-08 1999-02-18 Toyama Chemical Co., Ltd. Derives d'acide quinolonecarboxylique ou sels de ces derives
JP4669607B2 (ja) 1997-09-15 2011-04-13 ザ プロクター アンド ギャンブル カンパニー 抗微生物キノロン類、その組成物およびその使用
KR100565362B1 (ko) * 1997-10-27 2006-03-30 도야마 가가쿠 고교 가부시키가이샤 7-이소인돌린-퀴놀론 카복실산 유도체 및 그 중간체의 제조방법 및 7-이소인돌린-퀴놀론 카복실산 유도체의 염, 그의 수화물 및 이들을 활성성분으로 함유하는 조성물
JP4549461B2 (ja) * 1998-08-31 2010-09-22 富山化学工業株式会社 7−ブロモ−キノロンカルボン酸誘導体の製造法
JP4621356B2 (ja) * 1999-02-05 2011-01-26 富山化学工業株式会社 三環キノロンカルボン酸誘導体またはその塩
DE60014143T2 (de) 1999-10-19 2006-03-02 Sato Pharmaceutical Co., Ltd. Antimikrobielle 4-oxochinolizine mit 2-pyridongerüsten als teilstruktur
CN1202075C (zh) 2000-03-07 2005-05-18 兰贝克赛实验室有限公司 作为抗菌剂喹诺酮药物的有用中间体的3-环丙基氨基-2-[2,4-二溴-3-(二氟甲氧基 )苯甲酰基]-2-丙烯酸烷酯的-锅合成
JP2005232000A (ja) * 2000-03-10 2005-09-02 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体又はその塩
US6525049B2 (en) 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
CN1214792C (zh) * 2000-08-08 2005-08-17 第一制药株式会社 吸收性很好的固体制剂
JP2004515549A (ja) 2000-12-14 2004-05-27 ザ プロクター アンド ギャンブル カンパニー 抗微生物2−ピリドン類、その組成物と使用
DE60113450T2 (de) 2000-12-14 2006-07-13 The Procter & Gamble Company, Cincinnati Antimikrobielle chinolone
CN1243735C (zh) * 2001-04-19 2006-03-01 卫材株式会社 2-亚氨基吡咯烷衍生物
CN100337630C (zh) * 2002-03-12 2007-09-19 布里斯托尔-迈尔斯斯奎布公司 可口的口服悬浮液及其制备方法
EP2444393A1 (de) * 2003-02-19 2012-04-25 Eisai R&D Management Co., Ltd. Verfahren zur Herstellung von zyklischen Benzamidinderivaten
WO2007110835A2 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
DK2001862T3 (da) 2006-03-28 2011-08-08 Warner Chilcott Co Llc Malatsalte og polymorfe af (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyklopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolincarboxylsyre
JP2008031090A (ja) * 2006-07-28 2008-02-14 Toyota Central Res & Dev Lab Inc 有機スズ化合物及びその製造方法、並びに芳香族化合物誘導体の製造方法
CN101298418B (zh) * 2008-06-13 2010-12-15 江苏康鹏农化有限公司 3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法
CN102212056A (zh) * 2010-04-09 2011-10-12 山东轩竹医药科技有限公司 新的双环喹诺酮类化合物
KR101996697B1 (ko) 2011-08-31 2019-07-04 오쓰까 세이야꾸 가부시키가이샤 퀴놀론 화합물
TWI641372B (zh) 2013-03-15 2018-11-21 美商梅琳塔有限責任公司 使用抗生素治療超重和肥胖患者感染的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3248507A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen Mikrobizide mittel auf chinoloncarbonsaeure basis
ZA859283B (en) * 1984-12-06 1987-07-29 Pfizer Substituted dihydroquinolone carboxylic acids and anti-bacterial compositions containing them
DE3816119A1 (de) * 1988-05-11 1989-11-23 Bayer Ag 7-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
US4945160A (en) * 1988-11-22 1990-07-31 Warner-Lambert Company Preparation of certain 7-substituted quinolones

Also Published As

Publication number Publication date
ZA956713B (en) 1996-03-28
KR970704728A (ko) 1997-09-06
NO970622L (no) 1997-04-10
US5935952A (en) 1999-08-10
CN1070191C (zh) 2001-08-29
EP0775702A4 (de) 1997-11-05
EP0775702A1 (de) 1997-05-28
DE69531350T2 (de) 2004-05-27
FI113652B (fi) 2004-05-31
EP0775702B1 (de) 2003-07-23
CA2196271A1 (en) 1996-02-22
KR100371723B1 (ko) 2003-03-15
AU692583B2 (en) 1998-06-11
ES2203644T3 (es) 2004-04-16
FI970578A0 (fi) 1997-02-11
ATE245638T1 (de) 2003-08-15
NO312032B1 (no) 2002-03-04
FI970578A (fi) 1997-04-10
CA2196271C (en) 2007-01-09
WO1996005192A1 (fr) 1996-02-22
IL114875A (en) 1999-12-22
HUT77314A (hu) 1998-03-30
HU228062B1 (en) 2012-09-28
NZ290946A (en) 1997-12-19
AU3190695A (en) 1996-03-07
CN1158611A (zh) 1997-09-03
IL114875A0 (en) 1995-12-08
DK0775702T3 (da) 2003-08-18
NO970622D0 (no) 1997-02-11

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Legal Events

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8364 No opposition during term of opposition