ES2104761T3 - Derivado de benzotiazol. - Google Patents

Derivado de benzotiazol.

Info

Publication number
ES2104761T3
ES2104761T3 ES92105777T ES92105777T ES2104761T3 ES 2104761 T3 ES2104761 T3 ES 2104761T3 ES 92105777 T ES92105777 T ES 92105777T ES 92105777 T ES92105777 T ES 92105777T ES 2104761 T3 ES2104761 T3 ES 2104761T3
Authority
ES
Spain
Prior art keywords
group
chem
formula
lower alkyl
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92105777T
Other languages
English (en)
Inventor
Yasushi Okamoto
Katsuya Tagami
Shigeki Hibi
Hirotoshi Numata
Naoki Kobayashi
Masanobu Shinoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ES2104761T3 publication Critical patent/ES2104761T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Dental Preparations (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

DERIVADO DEL BENZOTIAZOL. UN DERIVADO DEL BENZOTIAZOL O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO QUE ES UTIL COMO AGENTE PREVENTIVO O TERAPEUTICO PARA ENFERMEDADES EN LAS QUE SON EFICACES LAS FUNCIONES DE SUPRESION DE PRODUCCION DE LEUCOTRIENOS Y TROMBOXANOS. UN DERIVADO DEL BENZOTIAZOL REPRESENTADO POR LA SIGUIENTE FORMULA GENERAL (I): EN DONDE R1 Y R3 SON LO MISMO O DISTINTO Y CADA UNO REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR, UN GRUPO ALCOXILO INFERIOR, UN GRUPO REPRESENTADO POR LA FORMULA: (EN DONDE P ES UN ENTERO DE 1 A 4), O UN GRUPO REPRESENTADO POR LA FORMULA: (EN DONDE R7 REPRESENTA UN GRUPO ALQUILO INFERIOR); R4 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR, UN GRUPO FENILO, UN GRUPO REPRESENTADO POR LA FORMULA: (EN DONDE Q ES UN ENTERO DE 1 A 4), O UN GRUPO REPRESENTADO POR LA FORMULA: (EN DONDE R7 REPRESENTA UN GRUPO ALQUILO INFERIOR); O R3 Y R4 PUEDEN FORMAR UN ANILLO DE BENCENO JUNTO CON ATOMOS DE CARBONO A LOS QUE ESTAN ENLAZADOS; R2 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO PROTECTOR DE UN GRUPO HIDROXILO; Y R5 Y R6 SON LO MISMO O DISTINTO Y CADA UNO REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR, UN GRUPO REPRESENTADO POR LA FORMULA: (EN DONDE R ES UN ENTERO DE 1 A 4) O UN GRUPO ACILO; O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO.
ES92105777T 1991-04-04 1992-04-03 Derivado de benzotiazol. Expired - Lifetime ES2104761T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7148091 1991-04-04
JP28136691 1991-10-28

Publications (1)

Publication Number Publication Date
ES2104761T3 true ES2104761T3 (es) 1997-10-16

Family

ID=26412577

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92105777T Expired - Lifetime ES2104761T3 (es) 1991-04-04 1992-04-03 Derivado de benzotiazol.

Country Status (19)

Country Link
US (3) US5300518A (es)
EP (1) EP0507318B1 (es)
KR (1) KR970000954B1 (es)
CN (1) CN1030451C (es)
AT (1) ATE157976T1 (es)
AU (1) AU658868B2 (es)
CA (1) CA2064992A1 (es)
DE (1) DE69222076T2 (es)
DK (1) DK0507318T3 (es)
ES (1) ES2104761T3 (es)
FI (1) FI921303A (es)
GR (1) GR3024867T3 (es)
HU (1) HU219448B (es)
IE (1) IE920921A1 (es)
MX (1) MX9201544A (es)
NO (1) NO301274B1 (es)
NZ (1) NZ242204A (es)
PH (1) PH30229A (es)
TW (1) TW198031B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5296486A (en) * 1991-09-24 1994-03-22 Boehringer Ingelheim Pharmaceuticals, Inc. Leukotriene biosynthesis inhibitors
WO1995004044A1 (fr) * 1993-07-30 1995-02-09 Eisai Co., Ltd. Procede de production de derives d'hydroquinone et de benzoquinone
GB9605065D0 (en) * 1996-03-11 1996-05-08 Merck Sharp & Dohme Therapeutic agents
DE69830929T2 (de) 1997-11-11 2006-04-20 Nikken Chemicals Co., Ltd. N-hydroxyurea-derivat und dieses enthaltende pharmazeutische zusammensetzung
EP1257536A1 (en) * 2000-01-27 2002-11-20 Cytovia, Inc. Substituted nicotinamides and analogs as activators of caspases and inducers of apoptosis and the use thereof
US20050124631A1 (en) * 2001-08-13 2005-06-09 Henning Bottcher Inhibitors of polyq-aggregation
CN103360339B (zh) * 2013-08-13 2015-05-13 安徽工业大学 一种绿色催化合成2′-氨基苯并噻唑-芳甲基-2-萘酚的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1931077A (en) * 1931-08-05 1933-10-17 Du Pont 1-amino-5-methoxy-benzo-thiazole
US4873346A (en) * 1985-09-20 1989-10-10 The Upjohn Company Substituted benzothiazoles, benzimidazoles, and benzoxazoles
US4763346A (en) * 1986-06-27 1988-08-09 Eastman Kodak Company Photographic cassette and method of dispensing
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
GB8820231D0 (en) * 1988-08-25 1988-09-28 Fujisawa Pharmaceutical Co New benzazole compounds processes for preparation thereof & pharmaceutical composition comprising same

Also Published As

Publication number Publication date
PH30229A (en) 1997-02-05
HUT62890A (en) 1993-06-28
DE69222076D1 (de) 1997-10-16
ATE157976T1 (de) 1997-09-15
TW198031B (es) 1993-01-11
HU9201141D0 (en) 1992-06-29
EP0507318A1 (en) 1992-10-07
FI921303A0 (fi) 1992-03-25
KR970000954B1 (ko) 1997-01-21
FI921303A (fi) 1992-10-05
DK0507318T3 (da) 1998-03-23
MX9201544A (es) 1992-10-01
DE69222076T2 (de) 1998-02-19
CN1030451C (zh) 1995-12-06
EP0507318B1 (en) 1997-09-10
CN1065457A (zh) 1992-10-21
US5300518A (en) 1994-04-05
US5420144A (en) 1995-05-30
NO301274B1 (no) 1997-10-06
CA2064992A1 (en) 1992-10-05
US5635519A (en) 1997-06-03
GR3024867T3 (en) 1998-01-30
NO921282D0 (no) 1992-04-02
NZ242204A (en) 1995-02-24
NO921282L (no) 1992-10-05
HU219448B (hu) 2001-04-28
AU658868B2 (en) 1995-05-04
KR920019785A (ko) 1992-11-20
IE920921A1 (en) 1992-10-07
AU1399092A (en) 1992-10-08

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