ZA956713B - Quinolone- or naphthylidone-carboxylic acid derivatives or their salts - Google Patents
Quinolone- or naphthylidone-carboxylic acid derivatives or their saltsInfo
- Publication number
- ZA956713B ZA956713B ZA956713A ZA956713A ZA956713B ZA 956713 B ZA956713 B ZA 956713B ZA 956713 A ZA956713 A ZA 956713A ZA 956713 A ZA956713 A ZA 956713A ZA 956713 B ZA956713 B ZA 956713B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- substituted
- hydrogen atom
- carboxylic acid
- lower alkyl
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21208394 | 1994-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA956713B true ZA956713B (en) | 1996-03-28 |
Family
ID=16616594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA956713A ZA956713B (en) | 1994-08-12 | 1995-08-11 | Quinolone- or naphthylidone-carboxylic acid derivatives or their salts |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5935952A (xx) |
| EP (1) | EP0775702B1 (xx) |
| KR (1) | KR100371723B1 (xx) |
| CN (1) | CN1070191C (xx) |
| AT (1) | ATE245638T1 (xx) |
| AU (1) | AU692583B2 (xx) |
| CA (1) | CA2196271C (xx) |
| DE (1) | DE69531350T2 (xx) |
| DK (1) | DK0775702T3 (xx) |
| ES (1) | ES2203644T3 (xx) |
| FI (1) | FI113652B (xx) |
| HU (1) | HU228062B1 (xx) |
| IL (1) | IL114875A (xx) |
| NO (1) | NO312032B1 (xx) |
| NZ (1) | NZ290946A (xx) |
| WO (1) | WO1996005192A1 (xx) |
| ZA (1) | ZA956713B (xx) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0846109B1 (en) * | 1995-08-21 | 2002-07-24 | Takeda Chemical Industries, Ltd. | Quinone compound, its production and use |
| IL124944A (en) * | 1996-02-09 | 2003-06-24 | Toyama Chemical Co Ltd | Quinolonecarboxylic acid derivatives or their salts and pharmaceutical compositions containing them |
| JP4370002B2 (ja) * | 1997-08-08 | 2009-11-25 | 富山化学工業株式会社 | キノロンカルボン酸誘導体またはその塩 |
| HUP0100051A3 (en) | 1997-09-15 | 2002-08-28 | Procter & Gamble | Antimicrobial quinolones, their compositions and uses |
| US6337399B1 (en) | 1997-10-27 | 2002-01-08 | Toyama Chemical Co., Ltd. | Processes for producing 7-isoindolinequinolonecarboxylic derivatives and intermediates therefor, salts of 7-isoindolinequinolonecarboxylic acids, hydrates thereof, and composition containing the same as active ingredient |
| JP4549461B2 (ja) * | 1998-08-31 | 2010-09-22 | 富山化学工業株式会社 | ７−ブロモ−キノロンカルボン酸誘導体の製造法 |
| WO2000046223A1 (fr) * | 1999-02-05 | 2000-08-10 | Toyama Chemical Co., Ltd. | Derives tricycliques d'acide quinolonecarboxylique ou sels de ces derives |
| ES2225237T3 (es) | 1999-10-19 | 2005-03-16 | Sato Pharmaceutical Co. Ltd. | Agentes antimicrobianos de tipo 4-oxoquinolizina que tienen cadenas principales de 2-piridona como estructura parcial. |
| CN1202075C (zh) * | 2000-03-07 | 2005-05-18 | 兰贝克赛实验室有限公司 | 作为抗菌剂喹诺酮药物的有用中间体的3－环丙基氨基－2－[2,4－二溴－3－(二氟甲氧基 )苯甲酰基]－2－丙烯酸烷酯的－锅合成 |
| JP2005232000A (ja) * | 2000-03-10 | 2005-09-02 | Dainippon Pharmaceut Co Ltd | ピリドンカルボン酸誘導体又はその塩 |
| US6525049B2 (en) | 2000-07-05 | 2003-02-25 | Pharmacia & Upjohn Company | Pyrroloquinolones as antiviral agents |
| CA2417764C (en) * | 2000-08-08 | 2009-05-05 | Katsuo Kataoka | Highly absorbable solid preparations containing sitafloxacin and tartaric acid |
| IL155678A0 (en) | 2000-12-14 | 2003-11-23 | Procter & Gamble | Antimicrobial 2-pyridones, their compositions and uses |
| ATE304539T1 (de) | 2000-12-14 | 2005-09-15 | Procter & Gamble | Antimikrobielle chinolone |
| DE60231608D1 (de) * | 2001-04-19 | 2009-04-30 | Eisai R&D Man Co Ltd | Cyclische amidinderivate |
| WO2003077842A2 (en) * | 2002-03-12 | 2003-09-25 | Bristol-Myers Squibb Company | Palatable oral suspension and method |
| CA2515715C (en) * | 2003-02-19 | 2012-05-08 | Eisai Co., Ltd. | Methods for producing cyclic benzamidine derivatives |
| WO2007110834A2 (en) | 2006-03-28 | 2007-10-04 | The Procter & Gamble Company | Malate salts, and polymorphs of (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid |
| JP2009531418A (ja) | 2006-03-28 | 2009-09-03 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体調製のためのカップリング方法 |
| JP2008031090A (ja) * | 2006-07-28 | 2008-02-14 | Toyota Central Res & Dev Lab Inc | 有機スズ化合物及びその製造方法、並びに芳香族化合物誘導体の製造方法 |
| CN101298418B (zh) * | 2008-06-13 | 2010-12-15 | 江苏康鹏农化有限公司 | 3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法 |
| CN102212056A (zh) * | 2010-04-09 | 2011-10-12 | 山东轩竹医药科技有限公司 | 新的双环喹诺酮类化合物 |
| CN105712976A (zh) | 2011-08-31 | 2016-06-29 | 大塚制药株式会社 | 喹诺酮化合物 |
| EP2969004A4 (en) | 2013-03-15 | 2016-09-21 | Melinta Therapeutics Inc | METHOD FOR THE TREATMENT OF INFECTIONS IN OVERWEIGHT AND ADIPOSIVE PATIENTS USING ANTIBIOTICS |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3248507A1 (de) * | 1982-12-29 | 1984-07-05 | Bayer Ag, 5090 Leverkusen | Mikrobizide mittel auf chinoloncarbonsaeure basis |
| ZA859283B (en) * | 1984-12-06 | 1987-07-29 | Pfizer | Substituted dihydroquinolone carboxylic acids and anti-bacterial compositions containing them |
| DE3816119A1 (de) * | 1988-05-11 | 1989-11-23 | Bayer Ag | 7-substituierte chinolon- und naphthyridoncarbonsaeure-derivate |
| JPH0262875A (ja) * | 1988-05-23 | 1990-03-02 | Wakunaga Pharmaceut Co Ltd | 新規イソインドリン誘導体 |
| US4945160A (en) * | 1988-11-22 | 1990-07-31 | Warner-Lambert Company | Preparation of certain 7-substituted quinolones |
-
1995
- 1995-08-04 WO PCT/JP1995/001551 patent/WO1996005192A1/ja active IP Right Grant
- 1995-08-04 NZ NZ290946A patent/NZ290946A/en not_active IP Right Cessation
- 1995-08-04 HU HU9701734A patent/HU228062B1/hu unknown
- 1995-08-04 DE DE69531350T patent/DE69531350T2/de not_active Expired - Lifetime
- 1995-08-04 EP EP95927967A patent/EP0775702B1/en not_active Expired - Lifetime
- 1995-08-04 AU AU31906/95A patent/AU692583B2/en not_active Expired
- 1995-08-04 AT AT95927967T patent/ATE245638T1/de active
- 1995-08-04 KR KR1019970700919A patent/KR100371723B1/ko not_active IP Right Cessation
- 1995-08-04 ES ES95927967T patent/ES2203644T3/es not_active Expired - Lifetime
- 1995-08-04 US US08/776,711 patent/US5935952A/en not_active Expired - Lifetime
- 1995-08-04 CA CA002196271A patent/CA2196271C/en not_active Expired - Lifetime
- 1995-08-04 DK DK95927967T patent/DK0775702T3/da active
- 1995-08-04 CN CN95195310A patent/CN1070191C/zh not_active Expired - Lifetime
- 1995-08-08 IL IL11487595A patent/IL114875A/xx not_active IP Right Cessation
- 1995-08-11 ZA ZA956713A patent/ZA956713B/xx unknown
-
1997
- 1997-02-11 FI FI970578A patent/FI113652B/fi not_active IP Right Cessation
- 1997-02-11 NO NO19970622A patent/NO312032B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI113652B (fi) | 2004-05-31 |
| AU3190695A (en) | 1996-03-07 |
| DE69531350T2 (de) | 2004-05-27 |
| KR100371723B1 (ko) | 2003-03-15 |
| DE69531350D1 (de) | 2003-08-28 |
| IL114875A (en) | 1999-12-22 |
| KR970704728A (ko) | 1997-09-06 |
| FI970578A (fi) | 1997-04-10 |
| CN1070191C (zh) | 2001-08-29 |
| NZ290946A (en) | 1997-12-19 |
| HUT77314A (hu) | 1998-03-30 |
| US5935952A (en) | 1999-08-10 |
| EP0775702A1 (en) | 1997-05-28 |
| WO1996005192A1 (fr) | 1996-02-22 |
| CA2196271A1 (en) | 1996-02-22 |
| ES2203644T3 (es) | 2004-04-16 |
| HU228062B1 (en) | 2012-09-28 |
| DK0775702T3 (da) | 2003-08-18 |
| CN1158611A (zh) | 1997-09-03 |
| NO970622L (no) | 1997-04-10 |
| EP0775702B1 (en) | 2003-07-23 |
| NO312032B1 (no) | 2002-03-04 |
| CA2196271C (en) | 2007-01-09 |
| AU692583B2 (en) | 1998-06-11 |
| NO970622D0 (no) | 1997-02-11 |
| FI970578A0 (fi) | 1997-02-11 |
| IL114875A0 (en) | 1995-12-08 |
| EP0775702A4 (en) | 1997-11-05 |
| ATE245638T1 (de) | 2003-08-15 |
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