EA199800466A1 - Замещеное производное аминоциклоалкилпирролидона - Google Patents

Замещеное производное аминоциклоалкилпирролидона

Info

Publication number
EA199800466A1
EA199800466A1 EA199800466A EA199800466A EA199800466A1 EA 199800466 A1 EA199800466 A1 EA 199800466A1 EA 199800466 A EA199800466 A EA 199800466A EA 199800466 A EA199800466 A EA 199800466A EA 199800466 A1 EA199800466 A1 EA 199800466A1
Authority
EA
Eurasian Patent Office
Prior art keywords
aminocycloalkylpyrrolidone
substituted derivative
chem
represented
formula
Prior art date
Application number
EA199800466A
Other languages
English (en)
Other versions
EA003321B1 (ru
Inventor
Макото Такемура
Юити Кимура
Хисаси Такахаси
Кенити Кимура
Сатору Мияути
Хитоси Оки
Original Assignee
Дайити Фармасьютикал Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дайити Фармасьютикал Ко., Лтд. filed Critical Дайити Фармасьютикал Ко., Лтд.
Publication of EA199800466A1 publication Critical patent/EA199800466A1/ru
Publication of EA003321B1 publication Critical patent/EA003321B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Предложены антибактериальные лекарственные средства, обладающие прекрасной антибактериальной активностью и высокой безвредностью, которые содержат в качестве активного ингредиента производные хинолона, содержащие в качестве заместителя аминоциклоалкилпирролидин и дополнительно замещенные различными заместителями, которые имеют формулу (I), его соли и гидраты:где фрагмент Q представляет собой формулу (II) или (IV):илиМеждународная заявка была опубликована вместе с отчетом о международном поиске.
EA199800466A 1995-11-22 1996-11-22 Производные аминоциклоалкилпирролидона и антибактериальное лекарственное средство на их основе EA003321B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30412995 1995-11-22
JP19263796 1996-07-23
PCT/JP1996/003440 WO1997019072A1 (fr) 1995-11-22 1996-11-22 Derives a base d'aminocycloalkylpyrrolidine substituee

Publications (2)

Publication Number Publication Date
EA199800466A1 true EA199800466A1 (ru) 1998-12-24
EA003321B1 EA003321B1 (ru) 2003-04-24

Family

ID=26507439

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800466A EA003321B1 (ru) 1995-11-22 1996-11-22 Производные аминоциклоалкилпирролидона и антибактериальное лекарственное средство на их основе

Country Status (15)

Country Link
EP (1) EP0911328B1 (ru)
JP (1) JP4040091B2 (ru)
KR (1) KR19990071558A (ru)
CN (1) CN1119343C (ru)
AT (1) ATE317393T1 (ru)
CA (1) CA2238765A1 (ru)
DE (1) DE69635812T2 (ru)
DK (1) DK0911328T3 (ru)
EA (1) EA003321B1 (ru)
ES (1) ES2258780T3 (ru)
NO (1) NO316516B1 (ru)
NZ (1) NZ322202A (ru)
PT (1) PT911328E (ru)
TW (1) TW402601B (ru)
WO (1) WO1997019072A1 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0807630T3 (da) * 1995-02-02 2003-09-01 Daiichi Seiyaku Co Heterocykliske forbindelser
EP1020459B1 (en) * 1997-05-21 2005-04-06 Daiichi Pharmaceutical Co., Ltd. Cis-disubstituted aminocycloalkyl-pyrrolidine derivatives
ZA984527B (en) * 1997-05-30 1998-12-03 Daiichi Seiyaku Co Substituted cyclobutylamine derivative
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
SK286420B6 (sk) 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
CN1343128B (zh) 1999-03-17 2010-04-21 第一制药株式会社 药物组合物
US6825353B2 (en) 2000-02-25 2004-11-30 Daiichi Pharmaceutical Co., Ltd. Process for producing quinolonecarboxylic acids and intermediates thereof
KR20020075447A (ko) * 2000-02-25 2002-10-04 다이이찌 세이야꾸 가부시기가이샤 퀴놀론카복실산의 제조방법 및 이의 중간체
KR100777149B1 (ko) * 2000-11-20 2007-11-19 다이이찌 세이야꾸 가부시기가이샤 데할로게노 화합물
JP4616770B2 (ja) * 2003-06-19 2011-01-19 第一三共株式会社 選択的なアミノ置換基導入法
EP1669354B1 (en) * 2003-09-29 2013-03-20 Daiichi Sankyo Company, Limited 8-cyanoquinolonecarboxylic acid derivative
CA2647454A1 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
BRPI0709772B8 (pt) 2006-03-28 2021-05-25 The Protecter & Gamble Company sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico
US7528264B2 (en) 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
CN102245570A (zh) * 2008-12-16 2011-11-16 弗·哈夫曼-拉罗切有限公司 制备吡咯烷-3-甲酸类的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE75740T1 (de) * 1985-06-26 1992-05-15 Daiichi Seiyaku Co Pyridoncarbonsaeurederivate.
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
KR100232937B1 (ko) * 1991-05-28 1999-12-01 스즈키 다다시 피리돈카복실산 유도체 및 이를 함유하는 항균제
DK0807630T3 (da) * 1995-02-02 2003-09-01 Daiichi Seiyaku Co Heterocykliske forbindelser

Also Published As

Publication number Publication date
NO982297L (no) 1998-07-22
WO1997019072A1 (fr) 1997-05-29
DK0911328T3 (da) 2006-06-06
CA2238765A1 (en) 1997-05-29
AU7589896A (en) 1997-06-11
NZ322202A (en) 2000-05-26
PT911328E (pt) 2006-05-31
KR19990071558A (ko) 1999-09-27
EP0911328A4 (ru) 1999-04-28
JP4040091B2 (ja) 2008-01-30
NO982297D0 (no) 1998-05-20
EP0911328B1 (en) 2006-02-08
NO316516B1 (no) 2004-02-02
CN1207738A (zh) 1999-02-10
EP0911328A1 (en) 1999-04-28
CN1119343C (zh) 2003-08-27
AU707889B2 (en) 1999-07-22
DE69635812T2 (de) 2006-10-19
ATE317393T1 (de) 2006-02-15
DE69635812D1 (de) 2006-04-20
ES2258780T3 (es) 2006-09-01
TW402601B (en) 2000-08-21
EA003321B1 (ru) 2003-04-24

Similar Documents

Publication Publication Date Title
EA199800466A1 (ru) Замещеное производное аминоциклоалкилпирролидона
ATE180468T1 (de) Anthranilsäure derivate
ATE282630T1 (de) Dolastatin-derivate
AU692090B2 (en) Novel 4,6-diarylpyrimidine derivatives and salts thereof
FI970578A (fi) Uusia kinoloni- tai naftyridonikarboksyylihappojohdannaisia tai niiden suola
FI940414A0 (fi) Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö
PT603887E (pt) Derivados de amina biciclicos
YU83993A (sh) Novi derivati piridon organske kiseline
PT947513E (pt) Derivados de amina triciclicos
DE60034577D1 (de) In 4-stellung substituierte piperidinderivate
AU6730600A (en) Vitamin d derivatives having substituents at the 2alpha-position

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU