YU83993A - Novi derivati piridon organske kiseline - Google Patents

Novi derivati piridon organske kiseline

Info

Publication number
YU83993A
YU83993A YU83993A YU83993A YU83993A YU 83993 A YU83993 A YU 83993A YU 83993 A YU83993 A YU 83993A YU 83993 A YU83993 A YU 83993A YU 83993 A YU83993 A YU 83993A
Authority
YU
Yugoslavia
Prior art keywords
group
lower alkyl
hydrogen atom
substituted
atom
Prior art date
Application number
YU83993A
Other languages
English (en)
Inventor
C.S. Kim
J.W. Kim
J.M. Lee
J.H. Cho
Y.S. Youn
Y.J. Shin
K.H. Lee
J.K. Kim
Y.H. Jung
S.H. An
Original Assignee
Cheil Foods And Chemicals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cheil Foods And Chemicals Inc. filed Critical Cheil Foods And Chemicals Inc.
Publication of YU83993A publication Critical patent/YU83993A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Dobijeni su novi derivati piridon karbonske kiseline i njihove farmaceutski prihvatljive soli i njihovi fiziološki hidrolizujući estri, predstavljeni formulom gde je Ri niža alkil, halogen-supstituisana niža alkil, niža alkenil, cikloalkil, ili supstituisana ili nesupstituisana fenil grupa; R2 je atom, vodonika, ili niža alkil ili amino grupa; A je atom azota ili grupa C-X gde je X atom vodonika ili halogena, ili akoksi grupa; i Z je grupa formule nižu alkil grupu pod uslovom da, ako je n=2, jedno od R3 i R4 je atom vodonika; R3 i R4 svako predstavlja atom vodonika ili hidroksi, nižu alkoksi ili amino grupu, koja je nesupstituisana ili supstituisana nižom alkil grupom, pod uslovom da je jedno od R5 ili R6 atom vodonika; i R7 je atom vodonika ili niža alkil grupa. Jedinjenja ovog pronalaska pokazuju snažan i širok spektar antibakterijskih aktivnosti.
YU83993A 1992-12-30 1993-12-30 Novi derivati piridon organske kiseline YU83993A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR920026696 1992-12-30
KR930011125 1993-06-17

Publications (1)

Publication Number Publication Date
YU83993A true YU83993A (sh) 1996-10-09

Family

ID=26629459

Family Applications (1)

Application Number Title Priority Date Filing Date
YU83993A YU83993A (sh) 1992-12-30 1993-12-30 Novi derivati piridon organske kiseline

Country Status (14)

Country Link
US (2) US5527910A (sh)
EP (1) EP0677050B1 (sh)
JP (1) JP2948660B2 (sh)
CN (1) CN1042632C (sh)
AT (1) ATE204272T1 (sh)
AU (2) AU689089B2 (sh)
CA (2) CA2226406C (sh)
DE (1) DE69330612D1 (sh)
HU (1) HU219581B (sh)
MX (1) MX9400113A (sh)
NO (2) NO307883B1 (sh)
RU (1) RU2161154C2 (sh)
WO (1) WO1994015933A1 (sh)
YU (1) YU83993A (sh)

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EP0664288A1 (en) * 1992-10-09 1995-07-26 Chugai Seiyaku Kabushiki Kaisha Fluoroquinoline derivative
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
DK0812838T3 (da) * 1994-02-04 2002-08-19 Dainippon Pharmaceutical Co Pyridoncarboxylsyrederivater substitueret med bicyclisk aminogruppe, estere og salte deraf og bicyclisk amin som mellemprodukt
CN1090185C (zh) * 1995-02-02 2002-09-04 大日本制药株式会社 有双环氨基取代的吡啶酮羧酸衍生物,其酯及盐,以及可用作其中间体的双环类胺
WO2000032611A1 (en) 1998-12-03 2000-06-08 Monsanto Technology Llc Cyanophosphonamides and method for preparation
WO2000054811A1 (fr) 1999-03-17 2000-09-21 Daiichi Pharmaceutical Co., Ltd. Compositions medicamenteuses
US7334538B1 (en) * 2004-07-27 2008-02-26 Aquascience Research Group, Inc. Topical medicants for aquatic animals
JP2010505861A (ja) * 2006-10-06 2010-02-25 ボーシュ アンド ローム インコーポレイティド キノロンカルボン酸と、その誘導体と、これらの製造法および利用法
US8252783B2 (en) 2007-01-24 2012-08-28 Bausch & Lomb Incorporated Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US7632944B2 (en) * 2007-01-24 2009-12-15 Bausch & Lomb Incorporated Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US7902227B2 (en) 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
BRPI1010981A2 (pt) 2009-05-15 2018-12-04 Redx Pharma Ltd "derivados de fármaco redox"
AU2012229997B2 (en) 2011-03-15 2016-04-14 Lawrence Livermore National Security, Llc Tricyclic gyrase inhibitors
KR102032934B1 (ko) * 2011-12-21 2019-10-16 지앙수 헨그루이 메디슨 컴퍼니 리미티드 피롤 6원 헤테로아릴 고리 유도체, 그의 제조 방법, 및 그의 의약 용도
EP2895488A1 (en) 2012-09-12 2015-07-22 Trius Therapeutics, Inc. Tricyclic gyrase inhibitors for use as antibacterial agents

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US3246027A (en) * 1961-03-22 1966-04-12 Du Pont Process for converting cis-1, 2-dicyanocy-clobutane to trans-1, 2-dicyanocyclobutane
US3246006A (en) * 1963-08-07 1966-04-12 Du Pont 2-(3-azabicyclo [3.2.0] hept-3-ylthio) benothiazole
NL6504082A (sh) * 1965-03-31 1966-10-03
US3639390A (en) * 1966-12-30 1972-02-01 Ciba Ltd Azabicycloalkane derivatives
US3875154A (en) * 1972-09-15 1975-04-01 Univ Ca Certain 5-thia-1-azabicyclo{8 4.2.0{9 octenes
EP0022288A3 (en) * 1979-07-06 1981-07-01 Shell Internationale Researchmaatschappij B.V. Method of sterilizing male anthers in plants, compositions and compounds suitable for use in such a method, and method of producing f1 hybrid seed
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4382937A (en) * 1981-02-27 1983-05-10 Dainippon Pharmaceutical Co., Ltd. Naphthyridine derivatives and their use as anti-bacterials
US4431661A (en) * 1981-08-20 1984-02-14 American Cyanamid Company 5-Aryl-3-azabicyclo[3.2.0]heptan-6-one acetals, and analgesic use therefor
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US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria

Also Published As

Publication number Publication date
CN1098103A (zh) 1995-02-01
RU95115237A (ru) 1997-06-10
NO952610L (no) 1995-08-29
HU9501727D0 (en) 1995-08-28
DE69330612D1 (de) 2001-09-20
CA2152817C (en) 1998-12-29
EP0677050B1 (en) 2001-08-16
HU219581B (hu) 2001-05-28
NO995638L (no) 1999-11-17
WO1994015933A1 (en) 1994-07-21
US5688965A (en) 1997-11-18
NO309087B1 (no) 2000-12-11
CA2226406A1 (en) 1994-07-21
NO307883B1 (no) 2000-06-13
AU3922097A (en) 1997-12-18
CA2226406C (en) 2001-08-14
AU704969B2 (en) 1999-05-13
US5527910A (en) 1996-06-18
AU689089B2 (en) 1998-03-26
AU5718194A (en) 1994-08-15
HUT72434A (en) 1996-04-29
JP2948660B2 (ja) 1999-09-13
RU2161154C2 (ru) 2000-12-27
CN1042632C (zh) 1999-03-24
JPH08505384A (ja) 1996-06-11
NO952610D0 (no) 1995-06-29
CA2152817A1 (en) 1994-07-21
NO995638D0 (no) 1999-11-17
MX9400113A (es) 1994-07-29
ATE204272T1 (de) 2001-09-15
EP0677050A1 (en) 1995-10-18

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