DE69330612D1 - Neue pyridon carbonsäure-derivate - Google Patents

Neue pyridon carbonsäure-derivate

Info

Publication number
DE69330612D1
DE69330612D1 DE69330612T DE69330612T DE69330612D1 DE 69330612 D1 DE69330612 D1 DE 69330612D1 DE 69330612 T DE69330612 T DE 69330612T DE 69330612 T DE69330612 T DE 69330612T DE 69330612 D1 DE69330612 D1 DE 69330612D1
Authority
DE
Germany
Prior art keywords
group
lower alkyl
hydrogen atom
substituted
pyridon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69330612T
Other languages
English (en)
Inventor
Sup Kim
Woong Kim
Mok Lee
Hwan Cho
Sik Youn
Jun Shin
Ho Lee
Hak Kim
Hwan Jung
Ho An
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ Corp
Original Assignee
CJ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CJ Corp filed Critical CJ Corp
Application granted granted Critical
Publication of DE69330612D1 publication Critical patent/DE69330612D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69330612T 1992-12-30 1993-12-29 Neue pyridon carbonsäure-derivate Expired - Lifetime DE69330612D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR920026696 1992-12-30
KR930011125 1993-06-17
PCT/KR1993/000123 WO1994015933A1 (en) 1992-12-30 1993-12-29 Novel pyridone carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
DE69330612D1 true DE69330612D1 (de) 2001-09-20

Family

ID=26629459

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69330612T Expired - Lifetime DE69330612D1 (de) 1992-12-30 1993-12-29 Neue pyridon carbonsäure-derivate

Country Status (14)

Country Link
US (2) US5527910A (de)
EP (1) EP0677050B1 (de)
JP (1) JP2948660B2 (de)
CN (1) CN1042632C (de)
AT (1) ATE204272T1 (de)
AU (2) AU689089B2 (de)
CA (2) CA2152817C (de)
DE (1) DE69330612D1 (de)
HU (1) HU219581B (de)
MX (1) MX9400113A (de)
NO (2) NO307883B1 (de)
RU (1) RU2161154C2 (de)
WO (1) WO1994015933A1 (de)
YU (1) YU83993A (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100236852B1 (ko) * 1992-10-09 2000-03-02 나가야마 오사무 플루오로 퀴놀린 유도체
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
ES2173175T3 (es) * 1994-02-04 2002-10-16 Dainippon Pharmaceutical Co Derivado de acido piridonacarboxilico sustituido con un grupo amino biciclico, ester del mismo, sal del mismo, y amina biciclica como intermedio para su preparacion.
CN1090185C (zh) * 1995-02-02 2002-09-04 大日本制药株式会社 有双环氨基取代的吡啶酮羧酸衍生物,其酯及盐,以及可用作其中间体的双环类胺
US6218563B1 (en) 1998-12-03 2001-04-17 Monsanto Company Cyanophosphonamides and method for preparation
CN1343128B (zh) 1999-03-17 2010-04-21 第一制药株式会社 药物组合物
US7334538B1 (en) * 2004-07-27 2008-02-26 Aquascience Research Group, Inc. Topical medicants for aquatic animals
MX2009003313A (es) * 2006-10-06 2009-04-09 Bausch & Lomb Acidos quinolona carboxilicos, derivados de los mismos, procesos para su preparacion y su uso como agentes antibacterianos.
US7632944B2 (en) * 2007-01-24 2009-12-15 Bausch & Lomb Incorporated Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US8252783B2 (en) 2007-01-24 2012-08-28 Bausch & Lomb Incorporated Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US7902227B2 (en) 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
KR20120025519A (ko) 2009-05-15 2012-03-15 레드엑스 파마 리미티드 산화환원 약물 유도체
MX345780B (es) 2011-03-15 2017-02-15 Trius Therapeutics Inc Inhibidores triciclicos de girasa.
WO2013091539A1 (zh) * 2011-12-21 2013-06-27 江苏恒瑞医药股份有限公司 吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用
US10865216B2 (en) 2012-09-12 2020-12-15 Merck Sharp & Dohme Corp. Tricyclic Gyrase inhibitors

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3252972A (en) * 1959-11-10 1966-05-24 Ciba Geigy Corp (n, n-bicycloalkylene-imino)-lower alkyl-guanidines
US3246027A (en) * 1961-03-22 1966-04-12 Du Pont Process for converting cis-1, 2-dicyanocy-clobutane to trans-1, 2-dicyanocyclobutane
US3246006A (en) * 1963-08-07 1966-04-12 Du Pont 2-(3-azabicyclo [3.2.0] hept-3-ylthio) benothiazole
NL6504082A (de) * 1965-03-31 1966-10-03
US3639390A (en) * 1966-12-30 1972-02-01 Ciba Ltd Azabicycloalkane derivatives
US3875154A (en) * 1972-09-15 1975-04-01 Univ Ca Certain 5-thia-1-azabicyclo{8 4.2.0{9 octenes
EP0022288A3 (de) * 1979-07-06 1981-07-01 Shell Internationale Researchmaatschappij B.V. Verfahren zum Sterilisieren männlicher Staubbeutel in Pflanzen, zur Verwendung in einem solchen Verfahren geeignete Zusammensetzungen und Verbindungen und Verfahren zur Herstellung von F1-gekreuzten Saatgütern
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4382937A (en) * 1981-02-27 1983-05-10 Dainippon Pharmaceutical Co., Ltd. Naphthyridine derivatives and their use as anti-bacterials
US4431661A (en) * 1981-08-20 1984-02-14 American Cyanamid Company 5-Aryl-3-azabicyclo[3.2.0]heptan-6-one acetals, and analgesic use therefor
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
IL77846A (en) * 1985-03-25 1989-08-15 Warner Lambert Co Process for the preparation of 7-amino-quinolin-4-oxy-3-carboxylic acid derivatives
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US4962108A (en) * 1987-07-31 1990-10-09 Warner-Lambert Company Antibacterial quinoline compounds
JPH0676400B2 (ja) * 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
WO1990002123A1 (en) * 1988-08-23 1990-03-08 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
US5147873A (en) * 1988-08-23 1992-09-15 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
WO1991002526A1 (en) * 1989-08-16 1991-03-07 Pfizer Inc. Azabicyclo quinolone carboxylic acids
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines
CA2076982A1 (en) * 1990-12-27 1992-06-28 Akira Okura Pyridonecarboxylic acid derivatives
DE4120646A1 (de) * 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
EP0549857A1 (de) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Chinolone Carbonsäurederivate verwendbar als antibakterielles Mittel
DE4219973A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria

Also Published As

Publication number Publication date
YU83993A (sh) 1996-10-09
EP0677050B1 (de) 2001-08-16
CA2226406C (en) 2001-08-14
NO995638D0 (no) 1999-11-17
HU9501727D0 (en) 1995-08-28
US5527910A (en) 1996-06-18
NO995638L (no) 1999-11-17
NO309087B1 (no) 2000-12-11
AU689089B2 (en) 1998-03-26
JP2948660B2 (ja) 1999-09-13
NO307883B1 (no) 2000-06-13
CN1098103A (zh) 1995-02-01
CA2226406A1 (en) 1994-07-21
US5688965A (en) 1997-11-18
RU2161154C2 (ru) 2000-12-27
AU3922097A (en) 1997-12-18
CA2152817C (en) 1998-12-29
WO1994015933A1 (en) 1994-07-21
CA2152817A1 (en) 1994-07-21
JPH08505384A (ja) 1996-06-11
HU219581B (hu) 2001-05-28
RU95115237A (ru) 1997-06-10
CN1042632C (zh) 1999-03-24
MX9400113A (es) 1994-07-29
EP0677050A1 (de) 1995-10-18
AU704969B2 (en) 1999-05-13
HUT72434A (en) 1996-04-29
ATE204272T1 (de) 2001-09-15
AU5718194A (en) 1994-08-15
NO952610D0 (no) 1995-06-29
NO952610L (no) 1995-08-29

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Legal Events

Date Code Title Description
8332 No legal effect for de