DE69506707D1 - Verfahren und vorrichtung zur herstellung von teilchen - Google Patents

Verfahren und vorrichtung zur herstellung von teilchen

Info

Publication number
DE69506707D1
DE69506707D1 DE69506707T DE69506707T DE69506707D1 DE 69506707 D1 DE69506707 D1 DE 69506707D1 DE 69506707 T DE69506707 T DE 69506707T DE 69506707 T DE69506707 T DE 69506707T DE 69506707 D1 DE69506707 D1 DE 69506707D1
Authority
DE
Germany
Prior art keywords
vehicle
supercritical fluid
suspension
solution
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69506707T
Other languages
English (en)
Other versions
DE69506707T2 (de
Inventor
Mazen Hanna
Peter York
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nektar Therapeutics UK Ltd
Original Assignee
University of Bradford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10757607&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69506707(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Bradford filed Critical University of Bradford
Publication of DE69506707D1 publication Critical patent/DE69506707D1/de
Application granted granted Critical
Publication of DE69506707T2 publication Critical patent/DE69506707T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0407—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solute
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0488—Flow sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
    • B01J3/008—Processes carried out under supercritical conditions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
    • B01J3/02—Feed or outlet devices therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Peptides Or Proteins (AREA)
DE69506707T 1994-06-30 1995-06-30 Verfahren und vorrichtung zur herstellung von teilchen Expired - Fee Related DE69506707T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9413202A GB9413202D0 (en) 1994-06-30 1994-06-30 Method and apparatus for the formation of particles
PCT/GB1995/001523 WO1996000610A1 (en) 1994-06-30 1995-06-30 Method and apparatus for the formation of particles

Publications (2)

Publication Number Publication Date
DE69506707D1 true DE69506707D1 (de) 1999-01-28
DE69506707T2 DE69506707T2 (de) 1999-07-01

Family

ID=10757607

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69506707T Expired - Fee Related DE69506707T2 (de) 1994-06-30 1995-06-30 Verfahren und vorrichtung zur herstellung von teilchen

Country Status (15)

Country Link
US (4) US6063138A (de)
EP (1) EP0767702B1 (de)
JP (1) JP3386470B2 (de)
AT (1) ATE174531T1 (de)
AU (1) AU688526B2 (de)
CA (1) CA2192811C (de)
DE (1) DE69506707T2 (de)
DK (1) DK0767702T3 (de)
ES (1) ES2128743T3 (de)
GB (1) GB9413202D0 (de)
GR (1) GR3029531T3 (de)
IN (1) IN191374B (de)
MX (1) MX9606730A (de)
WO (1) WO1996000610A1 (de)
ZA (1) ZA955437B (de)

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US20020010982A1 (en) 2002-01-31
US20060073087A1 (en) 2006-04-06
DE69506707T2 (de) 1999-07-01
GR3029531T3 (en) 1999-06-30
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GB9413202D0 (en) 1994-08-24
WO1996000610A1 (en) 1996-01-11
MX9606730A (es) 1997-04-30
EP0767702A1 (de) 1997-04-16
IN191374B (de) 2003-11-29
CA2192811C (en) 2004-11-16
DK0767702T3 (da) 1999-08-23
CA2192811A1 (en) 1996-01-11
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US20020073511A1 (en) 2002-06-20
US6063138A (en) 2000-05-16
ZA955437B (en) 1996-02-16

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