DK3302431T3 - Taxanpartikler og anvendelse deraf - Google Patents
Taxanpartikler og anvendelse deraf Download PDFInfo
- Publication number
- DK3302431T3 DK3302431T3 DK16732387.2T DK16732387T DK3302431T3 DK 3302431 T3 DK3302431 T3 DK 3302431T3 DK 16732387 T DK16732387 T DK 16732387T DK 3302431 T3 DK3302431 T3 DK 3302431T3
- Authority
- DK
- Denmark
- Prior art keywords
- taxan
- particles
- taxan particles
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/24—Particle separators, e.g. dust precipitators, using rigid hollow filter bodies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/26—Nozzle-type reactors, i.e. the distribution of the initial reactants within the reactor is effected by their introduction or injection through nozzles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
- B01J3/008—Processes carried out under supercritical conditions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
- B01J3/02—Feed or outlet devices therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/001—Feed or outlet devices as such, e.g. feeding tubes
- B01J4/002—Nozzle-type elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
- B05B1/34—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl
- B05B1/3405—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl
- B05B1/341—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
- B05B1/34—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl
- B05B1/3405—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl
- B05B1/341—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet
- B05B1/3489—Nozzles having concentric outlets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B13/00—Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups B05B1/00 - B05B11/00
- B05B13/02—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work
- B05B13/0278—Arrangement or mounting of spray heads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2271/00—Sealings for filters specially adapted for separating dispersed particles from gases or vapours
- B01D2271/02—Gaskets, sealings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2204/00—Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices
- B01J2204/002—Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices the feeding side being of particular interest
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D2401/00—Form of the coating product, e.g. solution, water dispersion, powders or the like
- B05D2401/90—Form of the coating product, e.g. solution, water dispersion, powders or the like at least one component of the composition being in supercritical state or close to supercritical state
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562171008P | 2015-06-04 | 2015-06-04 | |
US201562171060P | 2015-06-04 | 2015-06-04 | |
US201562171001P | 2015-06-04 | 2015-06-04 | |
PCT/US2016/035993 WO2016197091A1 (en) | 2015-06-04 | 2016-06-06 | Taxane particles and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3302431T3 true DK3302431T3 (da) | 2020-11-30 |
Family
ID=56194575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16732387.2T DK3302431T3 (da) | 2015-06-04 | 2016-06-06 | Taxanpartikler og anvendelse deraf |
Country Status (14)
Country | Link |
---|---|
US (11) | US9814685B2 (da) |
EP (4) | EP3302431B1 (da) |
JP (5) | JP6758325B2 (da) |
KR (5) | KR20200134347A (da) |
CN (4) | CN107683174B (da) |
AU (3) | AU2016270558B2 (da) |
CA (3) | CA3026452C (da) |
DK (1) | DK3302431T3 (da) |
ES (1) | ES2833749T3 (da) |
HK (3) | HK1253021B (da) |
PT (1) | PT3302431T (da) |
RU (1) | RU2750163C2 (da) |
SG (2) | SG10201913947RA (da) |
WO (3) | WO2016197101A1 (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3302431B1 (en) | 2015-06-04 | 2020-11-11 | Crititech, Inc. | Taxane particles and their use |
CA2998483C (en) | 2015-09-16 | 2022-09-06 | Dfb Soria, Llc | Delivery of drug nanoparticles and methods of use thereof |
CN109475492B (zh) | 2016-04-04 | 2022-04-29 | 克里蒂泰克公司 | 实体肿瘤治疗方法 |
CN108602258B (zh) * | 2016-05-12 | 2022-02-22 | 惠普发展公司有限责任合伙企业 | 构建材料容器 |
WO2018170210A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of vulvar intraepithelial neoplasia (vin) and genital warts using nanoparticles of taxanes |
WO2018170207A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of skin keratoses using nanoparticles of taxanes |
ES2955884T3 (es) | 2017-03-15 | 2023-12-07 | Dfb Soria Llc | Terapia tópica para el tratamiento de malignidades de la piel con nanoparticulas de taxanos |
JP2020523285A (ja) | 2017-06-09 | 2020-08-06 | クリチテック,インコーポレイテッド | 抗腫瘍粒子の嚢胞内注入による上皮嚢胞の治療 |
SG11201909837YA (en) * | 2017-06-14 | 2019-11-28 | Crititech Inc | Methods for treating lung disorders |
EP3648741A4 (en) * | 2017-07-07 | 2021-05-05 | DFB Pharmaceuticals, LLC | TREATMENT OF HYPERPLASTIC TISSUE GROWTH INCLUDING BENEFIT PROSTATE HYPERPLASIA (BPH) BY DIRECT INJECTION OF ANTINEOPLASTIC AGENT |
US11931368B2 (en) | 2017-09-29 | 2024-03-19 | Crititech, Inc. | Glucocorticoid “nintedanib” particles and their use |
EP3687977A1 (en) | 2017-09-29 | 2020-08-05 | Crititech, Inc. | Ciprofloxacin polymorph and its use |
CN111278436A (zh) * | 2017-10-03 | 2020-06-12 | 克里蒂泰克公司 | 局部递送抗肿瘤颗粒与全身递送免疫治疗剂相结合用于治疗癌症 |
US20190209515A1 (en) * | 2018-01-05 | 2019-07-11 | Crititech, Inc. | Treatment of Bladder Cancer by Intratumoral Injection of Taxane Particles |
US11497726B2 (en) | 2018-03-16 | 2022-11-15 | Dfb Soria, Ll. | Topical therapy for the treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer using nanoparticles of taxanes |
WO2019231499A1 (en) | 2018-05-31 | 2019-12-05 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for treatment of cancer |
KR20210016511A (ko) * | 2018-05-31 | 2021-02-16 | 크리티테크, 인크. | 입양 세포 요법 및 암 백신을 위한 종양 특이적 면역 세포를 대상체로부터 단리하는 방법 |
WO2019231498A1 (en) | 2018-05-31 | 2019-12-05 | Crititech, Inc. | Treatment of kidney tumors by intratumoral injection of taxane particles |
CN108970835B (zh) * | 2018-09-20 | 2020-11-17 | 马鞍山纽泽科技服务有限公司 | 一种耐高温喷射装置 |
WO2020072090A1 (en) | 2018-10-03 | 2020-04-09 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for production of tertiary lymphoid structures (tls) |
US11911499B2 (en) | 2019-11-07 | 2024-02-27 | Resurge Therapeutics, Inc. | System and method for prostate treatment |
CN115297857A (zh) * | 2020-02-04 | 2022-11-04 | 珠海贝海生物技术有限公司 | 多西他赛制剂 |
KR20230044423A (ko) | 2020-07-23 | 2023-04-04 | 크리티테크, 인크. | 라파티닙 입자 및 이의 용도 |
US20220241257A1 (en) * | 2020-07-23 | 2022-08-04 | Crititech, Inc. | Sorafenib particles and uses thereof |
CN113447635B (zh) * | 2021-05-11 | 2023-09-29 | 江西农业大学 | 一种盆栽类土壤不同深度温室气体释放速率测定装置 |
WO2023086779A1 (en) | 2021-11-10 | 2023-05-19 | Crititech, Inc. | Niraparib particles and uses thereof |
US11738029B2 (en) | 2021-11-10 | 2023-08-29 | Crititech, Inc. | Rucaparib particles and uses thereof |
US11957654B2 (en) | 2022-01-29 | 2024-04-16 | Resurge Therapeutics, Inc. | Treating benign prostatic hyperplasia |
US11974979B2 (en) | 2022-01-29 | 2024-05-07 | Resurge Therapeutics, Inc. | Treatments for benign prostatic hyperplasia |
Family Cites Families (154)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3648698A (en) * | 1969-05-23 | 1972-03-14 | George O Doherty | Surgical collection unit |
DE3120047C2 (de) * | 1981-05-20 | 1984-03-29 | Sterimed Gesellschaft für medizinischen Bedarf mbH, 6600 Saarbrücken | Sauggerät zum Ansaugen von Körpersekreten |
JPS5958019U (ja) | 1982-10-08 | 1984-04-16 | 松下電器産業株式会社 | 電気集塵機 |
US4780138A (en) * | 1986-10-27 | 1988-10-25 | Bodine Albert G | Sonic apparatus and method for facilitating the extraction of minerals from ore in a leachant |
US5143528A (en) | 1990-02-14 | 1992-09-01 | Challenge Industries | Lint collector |
US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
US6749868B1 (en) | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
WO1999000113A1 (en) | 1997-06-27 | 1999-01-07 | Vivorx Pharmaceuticals, Inc. | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
US5409833A (en) * | 1993-07-01 | 1995-04-25 | Baxter International Inc. | Microvessel cell isolation apparatus |
GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
GB9413202D0 (en) | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US5480540A (en) * | 1994-10-17 | 1996-01-02 | General Electric Company | Spray apparatus for separating solids from fluids |
US5874481A (en) | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
US5833891A (en) | 1996-10-09 | 1998-11-10 | The University Of Kansas | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents |
US5874029A (en) | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
CA2628857C (en) | 1996-12-30 | 2011-09-13 | Batelle Memorial Institute | Formulation and method for treating neoplasms by inhalation |
US6117949A (en) | 1998-10-01 | 2000-09-12 | Macromed, Inc. | Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
JPH11189403A (ja) | 1997-12-25 | 1999-07-13 | Tic:Kk | 層構造型複合粒子製造装置 |
JP3418751B2 (ja) | 1998-01-22 | 2003-06-23 | 参天製薬株式会社 | フルオロメトロン懸濁型点眼剤 |
IL131217A0 (en) | 1998-03-10 | 2001-01-28 | Napro Biotherapeutics Inc | Novel methods and compositions for delivery of taxanes |
US6221153B1 (en) | 1998-06-09 | 2001-04-24 | Trevor Percival Castor | Method for producing large crystals of complex molecules |
US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
US6113795A (en) | 1998-11-17 | 2000-09-05 | The University Of Kansas | Process and apparatus for size selective separation of micro- and nano-particles |
DK1131063T3 (da) | 1998-11-25 | 2003-07-21 | Universitaetsklinikum Freiburg | Hyperforinsalve eller -creme |
US6537585B1 (en) | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
US7217735B1 (en) | 1999-04-09 | 2007-05-15 | Au Jessie L-S | Methods and compositions for enhancing delivery of therapeutic agents to tissues |
JP4722295B2 (ja) * | 1999-05-27 | 2011-07-13 | エイカスフィアー・インコーポレーテッド | 多孔性薬剤マトリクスおよびその製造方法 |
US6610317B2 (en) | 1999-05-27 | 2003-08-26 | Acusphere, Inc. | Porous paclitaxel matrices and methods of manufacture thereof |
US6858199B1 (en) | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
US6616849B1 (en) | 1999-08-25 | 2003-09-09 | Shimadzu Corporation | Method of and system for continuously processing liquid materials, and the product processed thereby |
WO2001036007A2 (en) | 1999-11-12 | 2001-05-25 | Angiotech Pharmaceuticals, Inc. | Compositions of a combination of radioactive therapy and cell-cycle inhibitors |
SE515604C2 (sv) * | 2000-04-28 | 2001-09-10 | Bst Ab | Förfarande och anordning för uppsugning och transport av vätskor, företrädesvis blod |
US6620351B2 (en) | 2000-05-24 | 2003-09-16 | Auburn University | Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer |
US6562952B1 (en) | 2000-10-31 | 2003-05-13 | The University Of Kansas | Precipitation of proteins from organic solutions |
US20020081339A1 (en) | 2000-12-22 | 2002-06-27 | Philippe Menei | Treatment of inoperable tumors by stereotactic injection of microspheres |
US20020192280A1 (en) | 2001-05-01 | 2002-12-19 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating inflammatory conditions utilizing protein or polysaccharide containing anti-microtubule agents |
EP1401563B2 (en) | 2001-07-02 | 2015-09-16 | Micro & Nano Materials SAGL | Process for the production of micro and/or nano particles |
US20030054042A1 (en) | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
US20030134810A1 (en) | 2001-10-09 | 2003-07-17 | Chris Springate | Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents |
CN1592607A (zh) | 2001-10-15 | 2005-03-09 | 克里蒂泰克公司 | 水溶性差药物的组合物、其给药方法和治疗方法 |
US20030166509A1 (en) | 2001-11-20 | 2003-09-04 | Advanced Inhalation Research, Inc. | Compositions for sustained action product delivery and methods of use thereof |
US7138136B2 (en) | 2002-03-05 | 2006-11-21 | Cleveland State University | Agglomerated particles for aerosol drug delivery |
JP2003251127A (ja) | 2002-03-06 | 2003-09-09 | Kazuo Hirakawa | 集塵装置 |
CA2479665C (en) | 2002-03-20 | 2011-08-30 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
GB2387781A (en) * | 2002-04-25 | 2003-10-29 | Nektar Therapeutics Uk Ltd | Particulate materials |
EA200401250A1 (ru) | 2002-04-26 | 2005-06-30 | Тева Фармасьютикал Индастриес Лтд. | Фармацевтические композиции на основе микрочастиц для внутриопухолевого введения |
US9339459B2 (en) * | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
CN1255394C (zh) | 2002-06-24 | 2006-05-10 | 成都思摩纳米技术有限公司 | 紫杉醇纳米微粒的制备方法及应用 |
KR100573289B1 (ko) | 2002-07-20 | 2006-04-24 | 대화제약 주식회사 | 방광내 투여를 통한 방광암치료용 파클리탁셀 조성물 및그의 제조 방법 |
US6916389B2 (en) * | 2002-08-13 | 2005-07-12 | Nanotechnologies, Inc. | Process for mixing particulates |
CN2578811Y (zh) * | 2002-10-24 | 2003-10-08 | 陆纪清 | 全闭式煤粉取样装置 |
EP1569620A4 (en) * | 2002-10-30 | 2006-03-22 | Spherics Inc | NANOPARTICULAR BIOACTIVE AGENTS |
KR100508518B1 (ko) * | 2002-11-13 | 2005-08-17 | 한미약품 주식회사 | 초임계유체 공정을 이용한 파클리탁셀 고체분산체의 제조방법 및 이 방법으로 제조된 파클리탁셀 고체분산체 |
TR200502189T1 (tr) | 2002-12-09 | 2007-01-22 | American Bioscience, Inc. | Kompozisyonlar ve farmakolojik etken maddelerin aktarımı için yöntemler. |
US7455797B2 (en) | 2003-02-28 | 2008-11-25 | Ferro Corporation | Method and apparatus for producing particles using supercritical fluid |
WO2004089291A2 (en) | 2003-04-03 | 2004-10-21 | Au Jessie L-S | Tumor-targeting drug-loaded particles |
US20060147535A1 (en) | 2003-04-16 | 2006-07-06 | Poongunran Muthukumaran | Methods for and compositions of anticancer medicaments |
US20050059613A1 (en) | 2003-07-08 | 2005-03-17 | Bahram Memarzadeh | Compositions and methods for the enhanced uptake of therapeutic agents through the bladder epithelium |
US8021831B2 (en) | 2003-08-25 | 2011-09-20 | Board Of Regents, The University Of Texas System | Taxane chemosensitivity prediction test |
JP2007001865A (ja) | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤 |
HUE028648T2 (en) | 2003-10-15 | 2016-12-28 | Syncore Biotechnology Co Ltd | Use of cationic liposomes containing paclitaxel |
TWI371274B (en) * | 2003-10-23 | 2012-09-01 | Bristol Myers Squibb Co | Process for making sterile aripiprazole of desired mean particle size |
US7208106B2 (en) | 2003-10-24 | 2007-04-24 | Ferro Corporation | Method of forming particles |
ES2366646T3 (es) | 2003-11-05 | 2011-10-24 | Elan Pharma International Limited | Composiciones en forma de nanopartículas que tienen un péptido como estabilizante superficial. |
DE10357091A1 (de) * | 2003-12-06 | 2005-07-07 | Degussa Ag | Vorrichtung und Verfahren zur Abscheidung feinster Partikel aus der Gasphase |
GB0402963D0 (en) | 2004-02-11 | 2004-03-17 | Univ Nottingham | Counter current mixing device for two different fluids |
US8043631B2 (en) | 2004-04-02 | 2011-10-25 | Au Jessie L S | Tumor targeting drug-loaded particles |
JP5164381B2 (ja) | 2004-10-29 | 2013-03-21 | 株式会社奈良機械製作所 | 微細粒子の造粒方法 |
CA2588442A1 (en) | 2004-12-14 | 2006-06-29 | Transave, Inc. | Lipid particles comprising bioactive agents, methods of preparing and uses thereof |
ES2265262B1 (es) | 2005-01-31 | 2008-03-01 | Activery Biotech, S.L.(Titular Al 50%) | Procedimiento para la obtencion de sistemas micro- y nanodispersos. |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
BRPI0608173A2 (pt) * | 2005-02-24 | 2010-11-09 | Elan Pharma Int Ltd | composição, uso da mesma, e, método de produzir uma composição de docetaxel nanoparticulada ou análogo do mesmo |
US7872050B2 (en) | 2005-03-14 | 2011-01-18 | Yaupon Therapeutics Inc. | Stabilized compositions of volatile alkylating agents and methods of using thereof |
US8118795B2 (en) * | 2005-03-22 | 2012-02-21 | Medindica-Pak, Inc | Disposal chain supply systems method and apparatus |
PL1865924T3 (pl) | 2005-03-31 | 2016-06-30 | Lidds Ab | Sposób leczenia chorób gruczołu krokowego oparty na miejscowym dostarczaniu substancji czynnych |
CN1923189A (zh) | 2005-08-30 | 2007-03-07 | 孔庆忠 | 一种紫杉碱类抗癌药物的缓释注射剂 |
NZ592132A (en) | 2005-08-31 | 2012-12-21 | Abraxis Bioscience Llc | Composition comprising nanoparticles of docitaxel and a citrate |
EA013089B1 (ru) | 2005-12-11 | 2010-02-26 | Скф Технолоджис А/С | Получение наноразмерных материалов |
US8906392B2 (en) | 2005-12-16 | 2014-12-09 | University Of Kansas | Nanocluster compositions and methods |
AR054215A1 (es) * | 2006-01-20 | 2007-06-13 | Eriochem Sa | Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit |
CN101336899A (zh) | 2006-01-25 | 2009-01-07 | 济南帅华医药科技有限公司 | 含紫杉烷的抗癌缓释注射剂 |
JP5216601B2 (ja) | 2006-03-14 | 2013-06-19 | リッズ エービー | 生体吸収性の制御放出組成物 |
US7964029B2 (en) * | 2006-07-17 | 2011-06-21 | Thar Instrument, Inc. | Process flowstream collection system |
WO2008044092A1 (en) * | 2006-10-11 | 2008-04-17 | Renault Trucks | Truck provided with a passive keyless access system |
EP2077823B1 (en) | 2006-10-11 | 2012-06-27 | Crititech, Inc. | Method for precipitation of small medicament particles into use containers |
TWI405590B (zh) | 2007-04-06 | 2013-08-21 | Activus Pharma Co Ltd | 微粉碎化有機化合物粒子之製法 |
EP3326630A3 (en) | 2007-05-03 | 2018-08-29 | Abraxis BioScience, LLC | Methods and compositions for treating pulmonary hypertension |
US20100197944A1 (en) | 2007-07-04 | 2010-08-05 | Dr. Reddy's Laboratories Limited | Docetaxel process and polymorphs |
CN101129338A (zh) * | 2007-08-27 | 2008-02-27 | 四川大学 | 超临界流体新技术微细化抗癌药物紫杉醇 |
CA2716662A1 (en) | 2008-03-06 | 2009-03-11 | Nitto Denko Corporation | Polymer paclitaxel conjugates and methods for treating cancer |
US9056955B2 (en) * | 2008-03-24 | 2015-06-16 | Sanyo Chemical Industries, Ltd. | Resin particle comprising microparticle made of a crystalline resin, and method for producing the same |
RU2535017C2 (ru) | 2008-09-19 | 2014-12-10 | Активус Фарма Ко., Лтд. | Композитный порошок из органического вещества для применения в медицине, способ его получения и его суспензия |
CA2745238A1 (en) | 2008-12-02 | 2010-06-10 | Biocompatibles Uk Limited | Pancreatic tumour treatment |
PT104693B (pt) | 2009-07-27 | 2011-11-24 | Univ Lisboa | Nanopartículas lipídicas semi-sólidas contendo um agente antineoplásico e seu processo de preparação |
RU2012111349A (ru) | 2009-08-24 | 2013-10-27 | Байлор Колледж Оф Медсин | Генерация линий ctl со специфичностью против множества опухолевых антигенов или множества вирусов |
US20110209578A1 (en) * | 2010-02-26 | 2011-09-01 | Kuniaki Ara | Nanoparticle manufacturing device and nanoparticle manufacturing method and method of manufacturing nanoparticle-dispersed liquid alkali metal |
CN101829061A (zh) | 2010-05-14 | 2010-09-15 | 无锡纳生生物科技有限公司 | 一种紫杉醇纳米颗粒组合物及其制备方法 |
NZ708506A (en) | 2010-06-02 | 2016-08-26 | Abraxis Bioscience Llc | Methods of treating bladder cancer |
WO2012039602A1 (en) | 2010-09-21 | 2012-03-29 | Universiteit Utrecht Holding B.V. | Tunable, biodegradable linker molecules for transient conjugation of components in drug delivery systems, and drug delivery systems prepared therewith |
JP2014504260A (ja) | 2010-10-15 | 2014-02-20 | グラクソ グループ リミテッド | 集合ナノ粒子状薬物製剤、その製造及び使用 |
BR112013010575A2 (pt) * | 2010-10-29 | 2016-08-09 | Velico Medical Inc | conjunto de secagem por atomização, câmara de secagem por atomização, conjunto de cabeça de secagem por atomização, dispositivo de coleta de secagem por atomização, e, método para secar por atomização um líquido |
US20120177910A1 (en) * | 2011-01-11 | 2012-07-12 | Boston Scientific Scimed, Inc. | Coated Medical Devices |
CN104053432A (zh) | 2011-04-20 | 2014-09-17 | 悉尼大学 | 一种实体肿瘤的治疗方法 |
WO2013052158A2 (en) | 2011-04-26 | 2013-04-11 | William Marsh Rice University | Targeted nanovectors and their use for treatment of brain tumors |
CN107095863A (zh) | 2011-06-17 | 2017-08-29 | 博格有限责任公司 | 可吸入药物组合物 |
US10632131B2 (en) | 2011-06-27 | 2020-04-28 | Cristal Delivery B.V. | Controlled release system |
US11766459B2 (en) * | 2011-07-08 | 2023-09-26 | Jointechlabs, Inc. | System and methods for preparation of adipose-derived stem cells |
EP2750789B1 (en) * | 2011-08-31 | 2018-07-11 | Archer Daniels Midland Co. | Spray oxidation process for producing 2,5-furandicarboxylic acid from hydroxymethylfurfural |
FR2980683B1 (fr) | 2011-09-30 | 2014-11-21 | Univ Paris Curie | Dispositif de guidage d'un instrument medical insere dans une voie naturelle ou une voie artificielle d'un patient |
CN102319898B (zh) * | 2011-10-13 | 2013-05-08 | 西北工业大学 | 一种制备合金及金属基复合材料零部件的喷射成形系统 |
CN102488682A (zh) | 2011-11-22 | 2012-06-13 | 四川九章生物化工科技发展有限公司 | 绿原酸的抗癌新用途 |
JP2013212494A (ja) * | 2012-03-05 | 2013-10-17 | Ricoh Co Ltd | 樹脂微粒子の製造方法 |
US10555911B2 (en) | 2012-05-04 | 2020-02-11 | Yale University | Highly penetrative nanocarriers for treatment of CNS disease |
CN102728414A (zh) * | 2012-07-07 | 2012-10-17 | 中山大学 | 用于制备单壁碳纳米管的催化剂的制备方法及其运用 |
TW201408304A (zh) | 2012-08-31 | 2014-03-01 | Cathay General Hospital | 一種合併抗癌藥物及荷爾蒙之抗腎細胞癌藥物及其製造方法 |
WO2014046983A1 (en) | 2012-09-21 | 2014-03-27 | Intensity Therapeutic | Method of treating cancer |
WO2014081881A2 (en) * | 2012-11-20 | 2014-05-30 | Andrew Paul Joseph | Fluid-based extractor |
US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
WO2014132163A1 (en) | 2013-02-28 | 2014-09-04 | Pfizer Inc. | Enhanced stability of novel liquid compositions |
US8778181B1 (en) | 2013-03-14 | 2014-07-15 | Crititech, Inc. | Equipment assembly for and method of processing particles |
US9925512B2 (en) | 2013-03-14 | 2018-03-27 | Crititech, Inc. | Equipment assembly for and method of processing particles |
EP2978420A4 (en) | 2013-03-28 | 2016-12-21 | Bbs Nanotechnology Ltd | STABLE NANOCOMPOSITION COMPRISING PACLITAXEL, PROCESS FOR ITS PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
US9301926B2 (en) | 2013-04-10 | 2016-04-05 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
CN203699094U (zh) * | 2013-10-15 | 2014-07-09 | 雷海平 | 新式垃圾桶及配套内桶 |
EP3057619A1 (en) | 2013-10-16 | 2016-08-24 | Université Libre de Bruxelles | Formulations useful in the treatment of proliferative diseases affecting the respiratory tract |
AU2014364601A1 (en) | 2013-12-17 | 2016-07-07 | Genentech, Inc. | Methods of treating HER2-positive cancers using PD-1 axis binding antagonists and anti-HER2 antibodies |
KR20230076867A (ko) | 2013-12-20 | 2023-05-31 | 더 브로드 인스티튜트, 인코퍼레이티드 | 신생항원 백신과의 병용 요법 |
WO2015103005A1 (en) | 2014-01-03 | 2015-07-09 | Research Institute At Nationwide Children's Hospital | Amphiphilic amine compounds and their use as therapeutic agents and nanocarriers |
CN203737192U (zh) * | 2014-01-20 | 2014-07-30 | 四川西汉电子科技有限责任公司 | 一种造粒机 |
TWI601542B (zh) | 2014-04-18 | 2017-10-11 | 林信湧 | 一種用於治療肺癌之吸入式醫藥組成物及其備製方法 |
WO2015187194A1 (en) | 2014-06-01 | 2015-12-10 | Crititech, Inc. | Use of paclitaxel particles |
CN203847940U (zh) * | 2014-06-04 | 2014-09-24 | 刘希 | 一种加料喷嘴调节支架 |
WO2015191590A2 (en) | 2014-06-09 | 2015-12-17 | Biomed Valley Discoveries, Inc. | Combination therapies targeting tumor-associated stroma or tumor cells and microtubules |
US9533449B2 (en) * | 2014-06-19 | 2017-01-03 | Autodesk, Inc. | Material deposition systems with four or more axes |
EP3234193B1 (en) | 2014-12-19 | 2020-07-15 | Massachusetts Institute of Technology | Molecular biomarkers for cancer immunotherapy |
EP3302431B1 (en) * | 2015-06-04 | 2020-11-11 | Crititech, Inc. | Taxane particles and their use |
CA2998483C (en) * | 2015-09-16 | 2022-09-06 | Dfb Soria, Llc | Delivery of drug nanoparticles and methods of use thereof |
CA2995029C (en) | 2015-09-25 | 2022-10-25 | Zy Therapeutics Inc. | Drug formulation based on particulates comprising polysaccharide-vitamin conjugate |
DE202016006620U1 (de) | 2015-10-28 | 2017-04-12 | Qass Gmbh | Vorrichtungen zum Beobachten eines Magnetfelds eines Materialvolumens |
CN116376826A (zh) | 2016-01-20 | 2023-07-04 | 菲特治疗公司 | 用来在过继性免疫疗法中进行免疫细胞调节的组合物和方法 |
CN109475492B (zh) * | 2016-04-04 | 2022-04-29 | 克里蒂泰克公司 | 实体肿瘤治疗方法 |
CN107281502B (zh) | 2016-04-05 | 2021-05-04 | 上海市肿瘤研究所 | 一种复合显影温敏凝胶栓塞剂、制备方法及其应用 |
US10894093B2 (en) | 2016-04-15 | 2021-01-19 | Cellectis | Method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation |
US10160159B2 (en) * | 2016-05-12 | 2018-12-25 | Hewlett-Packard Development Company, L.P. | Build material container |
US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
EP3506942B1 (en) | 2016-09-01 | 2022-11-16 | Mayo Foundation for Medical Education and Research | Carrier-pd-l1 binding agent compositions for treating cancers |
WO2018170207A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of skin keratoses using nanoparticles of taxanes |
WO2018170210A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of vulvar intraepithelial neoplasia (vin) and genital warts using nanoparticles of taxanes |
ES2955884T3 (es) | 2017-03-15 | 2023-12-07 | Dfb Soria Llc | Terapia tópica para el tratamiento de malignidades de la piel con nanoparticulas de taxanos |
JP2020523285A (ja) | 2017-06-09 | 2020-08-06 | クリチテック,インコーポレイテッド | 抗腫瘍粒子の嚢胞内注入による上皮嚢胞の治療 |
SG11201909837YA (en) | 2017-06-14 | 2019-11-28 | Crititech Inc | Methods for treating lung disorders |
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2016
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2019
- 2019-10-30 US US16/669,310 patent/US11123322B2/en active Active
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2020
- 2020-01-30 US US16/776,919 patent/US10729673B2/en active Active
- 2020-09-01 JP JP2020146459A patent/JP7096299B2/ja active Active
- 2020-09-16 US US17/023,098 patent/US20200405684A1/en not_active Abandoned
- 2020-09-17 US US17/023,635 patent/US10993927B2/en active Active
-
2021
- 2021-09-07 US US17/467,655 patent/US20210393569A1/en active Pending
-
2022
- 2022-06-23 JP JP2022101327A patent/JP2022121532A/ja active Pending
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