ATE283110T1 - Verfahren zur herstellung von teilchen - Google Patents

Verfahren zur herstellung von teilchen

Info

Publication number
ATE283110T1
ATE283110T1 AT99937888T AT99937888T ATE283110T1 AT E283110 T1 ATE283110 T1 AT E283110T1 AT 99937888 T AT99937888 T AT 99937888T AT 99937888 T AT99937888 T AT 99937888T AT E283110 T1 ATE283110 T1 AT E283110T1
Authority
AT
Austria
Prior art keywords
fluid
suspension
solution
substance
inlet means
Prior art date
Application number
AT99937888T
Other languages
English (en)
Inventor
Mazen Hermiz Hanna
Gwynfor Owen Humphreys
Richard Storey
Boris Shekunov
Original Assignee
Nektar Therapeutics Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics Uk Ltd filed Critical Nektar Therapeutics Uk Ltd
Application granted granted Critical
Publication of ATE283110T1 publication Critical patent/ATE283110T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT99937888T 1998-03-02 1999-02-26 Verfahren zur herstellung von teilchen ATE283110T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9804379.7A GB9804379D0 (en) 1998-03-02 1998-03-02 Method of particle formation
PCT/GB1999/000587 WO1999044733A1 (en) 1998-03-02 1999-02-26 Method of particle formation

Publications (1)

Publication Number Publication Date
ATE283110T1 true ATE283110T1 (de) 2004-12-15

Family

ID=10827831

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99937888T ATE283110T1 (de) 1998-03-02 1999-02-26 Verfahren zur herstellung von teilchen

Country Status (11)

Country Link
EP (1) EP1060008B1 (de)
JP (1) JP4593777B2 (de)
AT (1) ATE283110T1 (de)
AU (1) AU753115B2 (de)
CA (1) CA2321741C (de)
DE (1) DE69922173T2 (de)
ES (1) ES2232158T3 (de)
GB (2) GB9804379D0 (de)
MX (1) MXPA00008428A (de)
WO (1) WO1999044733A1 (de)
ZA (1) ZA991667B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4874483B2 (ja) 1999-06-09 2012-02-15 ロバート イー． シーバース 超臨界流体補助ネブライゼーション及びバブル乾燥
GB9915975D0 (en) * 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
AU2002221320B2 (en) * 2000-12-08 2006-06-15 The University Of Sydney Synthesis of small particles
AUPR197000A0 (en) 2000-12-08 2001-01-11 Unisearch Limited Synthesis of small particles
GB0102075D0 (en) 2001-01-26 2001-03-14 Astrazeneca Ab Process
EP1414633A4 (de) * 2001-07-10 2005-01-26 Univ Technology Corp Vorrichtung und verfahren zur herstellung von teilchen
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB0126716D0 (en) * 2001-11-07 2002-01-02 Advanced Phytonics Ltd Method for the production of particles
CA2524773C (en) 2003-05-08 2014-04-08 Nektar Therapeutics Uk Ltd Particulate coformulations of active substances with excipients
US8475845B2 (en) 2005-07-15 2013-07-02 Map Pharmaceuticals, Inc. Method of particle formation
WO2008070279A2 (en) 2006-10-11 2008-06-12 Crititech, Inc. Method for precipitation of small medicament particles into use containers
ES2691033T3 (es) 2007-02-11 2018-11-23 Map Pharmaceuticals Inc. Método de administración terapéutica de DHE para activar el alivio rápido de la migraña a la vez que se reduce al mínimo el perfil de los efectos secundarios
CN101918123B (zh) 2007-12-07 2013-12-18 X喷雾微粒公司 生产微粒的方法与装置
US8367427B2 (en) 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US8323685B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US9808030B2 (en) 2011-02-11 2017-11-07 Grain Processing Corporation Salt composition
GB201402556D0 (en) 2014-02-13 2014-04-02 Crystec Ltd Improvements relating to inhalable particles
WO2017013498A2 (en) 2015-07-22 2017-01-26 Anavex Life Sciences Corp. Crystal forms of tetra-hydro-n, n-dimethyl-2, 2-diphenyl-3-furanmethanamine hydrochloride, processes for making such forms, and their pharmaceutical compositions
CN111530103B (zh) * 2020-05-08 2021-08-31 福建蓝烟新材料有限公司 一种超临界喷雾干燥方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SI9400079B (sl) * 1994-02-15 2003-02-28 Dr. Weidner Eckhard, Dipl. Ing. Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
JP3986086B2 (ja) * 1996-03-01 2007-10-03 ザ ユニバーシティ オブ カンザス 近臨界および超臨界反溶媒を用いる粒子析出方法および被覆方法
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US6228394B1 (en) * 1997-10-14 2001-05-08 Boehringer Ingelheim Pharmaceuticals, Inc. Supercritical fluid extraction of mould lubricant from hard shell capsules

Also Published As

Publication number Publication date
GB9904658D0 (en) 1999-04-21
CA2321741C (en) 2007-10-30
JP4593777B2 (ja) 2010-12-08
EP1060008A1 (de) 2000-12-20
DE69922173T2 (de) 2005-12-01
JP2002505182A (ja) 2002-02-19
WO1999044733A1 (en) 1999-09-10
MXPA00008428A (es) 2003-04-25
CA2321741A1 (en) 1999-09-10
ZA991667B (en) 1999-11-16
AU3260199A (en) 1999-09-20
GB9804379D0 (en) 1998-04-22
DE69922173D1 (de) 2004-12-30
GB2334900B (en) 2000-04-19
ES2232158T3 (es) 2005-05-16
EP1060008B1 (de) 2004-11-24
GB2334900A (en) 1999-09-08
AU753115B2 (en) 2002-10-10

Similar Documents

Publication Publication Date Title
ATE283110T1 (de) Verfahren zur herstellung von teilchen
DE69905460D1 (de) Verfahren und vorrichtung zur herstellung von partikeln
ATE266463T1 (de) Verfahren und vorrichtung zur herstellung von teilchen
HK1008213A1 (en) Wastewater treatment method and plant
DE69908655D1 (de) Verfahren zur herstellung von stärketeilchen
ATE174531T1 (de) Verfahren und vorrichtung zur herstellung von teilchen
ATE307092T1 (de) Verfahren zur behandlung von wasser durch ballastiertes ausflocken und dekantieren
DE69426934D1 (de) Verfahren zur konditionierung von substanzen
GB2320208A (en) Process and means for separation of a well production stream
ATE131859T1 (de) Verfahren zur kontinuierlichen extraction von torf und apparat zur durchführung dieses verfahrens
ATE302647T1 (de) Verfahren und vorrichtung zur herstellung von teilchen
ZA200607729B (en) Process for solids suspension and dosing
SU1601108A1 (ru) Способ деэмульсации нефти
UA41905C2 (uk) Спосіб виготовлення глинозему за методом бауера
JPS5599359A (en) Setting method of piping in multistage type hydro cyclone system
AU1184601A (en) Method and means for mixing
MX9604001A (es) Proceso para recuperar eteres de celulosa a partir de un medio acuoso que contiene tales eteres de celulosa.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties