DE69301311D1 - Selbst-agglomerierendes diketopiperazin-arzneistoffabgabesystem - Google Patents

Selbst-agglomerierendes diketopiperazin-arzneistoffabgabesystem

Info

Publication number
DE69301311D1
DE69301311D1 DE69301311T DE69301311T DE69301311D1 DE 69301311 D1 DE69301311 D1 DE 69301311D1 DE 69301311 T DE69301311 T DE 69301311T DE 69301311 T DE69301311 T DE 69301311T DE 69301311 D1 DE69301311 D1 DE 69301311D1
Authority
DE
Germany
Prior art keywords
microparticles
drug delivery
diketopiperazine
stable
agglomerating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69301311T
Other languages
English (en)
Other versions
DE69301311T2 (de
Inventor
Robert Feldstein
John Glass
Solomon S Steiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mannkind Corp
Original Assignee
Pharmaceutical Discovery Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaceutical Discovery Corp filed Critical Pharmaceutical Discovery Corp
Publication of DE69301311D1 publication Critical patent/DE69301311D1/de
Application granted granted Critical
Publication of DE69301311T2 publication Critical patent/DE69301311T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
DE69301311T 1992-03-11 1993-03-11 Selbst-agglomerierendes diketopiperazin-arzneistoffabgabesystem Expired - Lifetime DE69301311T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/849,186 US5352461A (en) 1992-03-11 1992-03-11 Self assembling diketopiperazine drug delivery system
PCT/US1993/002245 WO1993018754A1 (en) 1992-03-11 1993-03-11 Self-assembling diketopiperazine drug delivery system

Publications (2)

Publication Number Publication Date
DE69301311D1 true DE69301311D1 (de) 1996-02-22
DE69301311T2 DE69301311T2 (de) 1996-08-22

Family

ID=25305266

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69301311T Expired - Lifetime DE69301311T2 (de) 1992-03-11 1993-03-11 Selbst-agglomerierendes diketopiperazin-arzneistoffabgabesystem

Country Status (11)

Country Link
US (2) US5352461A (de)
EP (1) EP0630236B1 (de)
JP (1) JP2617273B2 (de)
AT (1) ATE132744T1 (de)
AU (1) AU680408B2 (de)
CA (1) CA2131366C (de)
DE (1) DE69301311T2 (de)
DK (1) DK0630236T3 (de)
ES (1) ES2089844T3 (de)
GR (1) GR3019622T3 (de)
WO (1) WO1993018754A1 (de)

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EP0630236B1 (de) 1996-01-10
CA2131366C (en) 2003-09-23
US5352461A (en) 1994-10-04
AU680408B2 (en) 1997-07-31
AU3804493A (en) 1993-10-21
US5503852A (en) 1996-04-02
WO1993018754A1 (en) 1993-09-30
ES2089844T3 (es) 1996-10-01
DE69301311T2 (de) 1996-08-22
JP2617273B2 (ja) 1997-06-04
CA2131366A1 (en) 1993-09-30
GR3019622T3 (en) 1996-07-31
DK0630236T3 (da) 1996-06-03
EP0630236A1 (de) 1994-12-28
ATE132744T1 (de) 1996-01-15

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