DE69221147T2 - Nicht glycosylierter Anti-CD3-IgG-Antikörper - Google Patents
Nicht glycosylierter Anti-CD3-IgG-AntikörperInfo
- Publication number
- DE69221147T2 DE69221147T2 DE69221147T DE69221147T DE69221147T2 DE 69221147 T2 DE69221147 T2 DE 69221147T2 DE 69221147 T DE69221147 T DE 69221147T DE 69221147 T DE69221147 T DE 69221147T DE 69221147 T2 DE69221147 T2 DE 69221147T2
- Authority
- DE
- Germany
- Prior art keywords
- ser
- gly
- thr
- val
- asp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929206422A GB9206422D0 (en) | 1992-03-24 | 1992-03-24 | Antibody preparation |
| PCT/GB1992/001933 WO1993019196A1 (en) | 1992-03-24 | 1992-10-21 | ANTI-CD3 AGLYCOSYLATED IgG ANTIBODY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69221147D1 DE69221147D1 (de) | 1997-09-04 |
| DE69221147T2 true DE69221147T2 (de) | 1998-01-15 |
Family
ID=10712757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69221147T Expired - Lifetime DE69221147T2 (de) | 1992-03-24 | 1992-10-21 | Nicht glycosylierter Anti-CD3-IgG-Antikörper |
Country Status (12)
| Country | Link |
|---|---|
| US (11) | US5585097A (cg-RX-API-DMAC10.html) |
| EP (1) | EP0586617B1 (cg-RX-API-DMAC10.html) |
| JP (3) | JP4065554B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR100238497B1 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE155818T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU671085B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2109815C (cg-RX-API-DMAC10.html) |
| DE (1) | DE69221147T2 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2106195T3 (cg-RX-API-DMAC10.html) |
| GB (1) | GB9206422D0 (cg-RX-API-DMAC10.html) |
| GR (1) | GR3024489T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO1993019196A1 (cg-RX-API-DMAC10.html) |
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1992
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| US20060269547A1 (en) | 2006-11-30 |
| ATE155818T1 (de) | 1997-08-15 |
| US20070178092A1 (en) | 2007-08-02 |
| JP4065554B2 (ja) | 2008-03-26 |
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| US20040202657A1 (en) | 2004-10-14 |
| JP2006089501A (ja) | 2006-04-06 |
| EP0586617A1 (en) | 1994-03-16 |
| GB9206422D0 (en) | 1992-05-06 |
| CA2109815A1 (en) | 1993-09-30 |
| DE69221147D1 (de) | 1997-09-04 |
| US20060088526A1 (en) | 2006-04-27 |
| JP4113890B2 (ja) | 2008-07-09 |
| US20060165693A1 (en) | 2006-07-27 |
| US6706265B1 (en) | 2004-03-16 |
| JP4113467B2 (ja) | 2008-07-09 |
| AU671085B2 (en) | 1996-08-15 |
| JP2004000249A (ja) | 2004-01-08 |
| JPH07500017A (ja) | 1995-01-05 |
| CA2109815C (en) | 2003-02-04 |
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