DE69201793T2 - Mehrschichtige zubereitung mit kontrollierter freisetzung. - Google Patents

Mehrschichtige zubereitung mit kontrollierter freisetzung.

Info

Publication number
DE69201793T2
DE69201793T2 DE69201793T DE69201793T DE69201793T2 DE 69201793 T2 DE69201793 T2 DE 69201793T2 DE 69201793 T DE69201793 T DE 69201793T DE 69201793 T DE69201793 T DE 69201793T DE 69201793 T2 DE69201793 T2 DE 69201793T2
Authority
DE
Germany
Prior art keywords
controlled release
multilayered
preparation
sustainably
periphery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69201793T
Other languages
English (en)
Other versions
DE69201793D1 (de
Inventor
Kazuo Noda
Hiroyuki Yoshino
Yoshiyuki Hirakawa
David Maclaren
Paul Skultety
John Lefler
Greg Beck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Aventis Pharmaceuticals Inc
Original Assignee
Tanabe Seiyaku Co Ltd
Marion Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd, Marion Laboratories Inc filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE69201793D1 publication Critical patent/DE69201793D1/de
Publication of DE69201793T2 publication Critical patent/DE69201793T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69201793T 1991-05-20 1992-05-20 Mehrschichtige zubereitung mit kontrollierter freisetzung. Expired - Lifetime DE69201793T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70285491A 1991-05-20 1991-05-20
PCT/US1992/004267 WO1992020326A1 (en) 1991-05-20 1992-05-20 Multi-layered controlled release formulation

Publications (2)

Publication Number Publication Date
DE69201793D1 DE69201793D1 (de) 1995-04-27
DE69201793T2 true DE69201793T2 (de) 1995-09-21

Family

ID=24822867

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69201793T Expired - Lifetime DE69201793T2 (de) 1991-05-20 1992-05-20 Mehrschichtige zubereitung mit kontrollierter freisetzung.

Country Status (11)

Country Link
US (1) US5320853A (de)
EP (1) EP0585355B1 (de)
JP (1) JP3426230B2 (de)
AT (1) ATE120089T1 (de)
AU (1) AU2016992A (de)
DE (1) DE69201793T2 (de)
DK (1) DK0585355T3 (de)
ES (1) ES2073301T3 (de)
GR (1) GR3015737T3 (de)
NZ (1) NZ242806A (de)
WO (1) WO1992020326A1 (de)

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US5376384A (en) * 1992-12-23 1994-12-27 Kinaform Technology, Inc. Delayed, sustained-release pharmaceutical preparation
WO1996010996A1 (en) * 1993-07-21 1996-04-18 The University Of Kentucky Research Foundation A multicompartment hard capsule with control release properties
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5645858A (en) * 1994-10-06 1997-07-08 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
WO1996019974A1 (fr) * 1994-12-27 1996-07-04 Kanebo, Ltd. Preparation a liberation prolongee
US5834024A (en) 1995-01-05 1998-11-10 Fh Faulding & Co. Limited Controlled absorption diltiazem pharmaceutical formulation
FR2754177B1 (fr) * 1996-10-07 1999-08-06 Sanofi Sa Microspheres pharmaceutiques d'acide valproique pour administration orale
US5885616A (en) * 1997-08-18 1999-03-23 Impax Pharmaceuticals, Inc. Sustained release drug delivery system suitable for oral administration
US6602521B1 (en) 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR20020059653A (ko) 1999-10-29 2002-07-13 그린 마틴, 브라이언 쥐 테슬리 서방성 하이드로코돈 제형
EP1252887A4 (de) 2000-01-27 2009-07-29 Mitsubishi Tanabe Pharma Corp Zubereitung mit verlängerter freisetzung und prozess zu deren herstellung
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
HU230686B1 (en) 2000-10-30 2017-08-28 Euro Celtique Sa Controlled release hydrocodone compositions
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
GB0310919D0 (en) * 2003-05-13 2003-06-18 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
ES2228268B1 (es) * 2003-07-30 2006-07-01 Laboratorios Del Dr. Esteve, S.A. Combinacion de sustancias activas conteniendo al menos un compuesto con afinidad por el receptor del neuropeptido y (npy) y al menos un compuesto con afinidad por el receptor 5-ht6.
ES2228267B1 (es) * 2003-07-30 2006-07-01 Laboratorios Del Dr. Esteve, S.A. Combinacion de sustancias activas conteniendo al menos un compuesto con afinidad por el receptor del neuropeptido y (npy) y al menos un compuesto con afinidad por el receptor 5-ht6.
JP4468669B2 (ja) * 2003-09-22 2010-05-26 久光製薬株式会社 低刺激性貼付剤
DE10353196A1 (de) * 2003-11-13 2005-06-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform mit einer die Abgabe einer modulatorischen Substanz beeinflussenden Matrix
DE10353186A1 (de) * 2003-11-13 2005-06-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz
JP2008508227A (ja) * 2004-07-29 2008-03-21 サノフイ−アベンテイス 高ｐｈ依存性溶解度を有する有効成分の放出制御のための医薬品多層錠剤
DK1836665T3 (da) * 2004-11-19 2013-04-15 Glaxosmithkline Llc Fremgangsmåde til specialtilpasset afgivelse af medikamentkombinationsprodukter med variabel dosis til individualisering af terapier
ZA200806496B (en) * 2006-01-27 2009-12-30 Eurand Inc Drug delivery systems comprising weakly basic drugs and organic acids
NZ570039A (en) * 2006-01-27 2011-07-29 Eurand Inc Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acids
WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
EP3050568B1 (de) 2007-03-13 2020-12-02 JDS Therapeutics, LLC Verfahren und zusammensetzungen zur verzögerten freisetzung von chrom
US8679541B2 (en) 2007-03-14 2014-03-25 Particle Dynamics International, Llc Spatial arrangement of particles in a drinking device for oral delivery of pharmaceuticals
WO2008128140A1 (en) * 2007-04-13 2008-10-23 The Regents Of The University Of Michigan Delivery device and method for forming the same
WO2009002867A2 (en) * 2007-06-26 2008-12-31 Nutrition 21, Inc. Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
CA3018328A1 (en) 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
GB2564295A (en) 2016-02-11 2019-01-09 Nutrition 21 Llc Chromium containing compositions for improving health and fitness
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

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GB768512A (en) * 1954-08-16 1957-02-20 Smith Kline & French Internat Improvements in or relating to pharmaceutical tablets
GB874586A (en) * 1957-10-28 1961-08-10 Upjohn Co Improvements in or relating to therapeutic compositions and the manufacture thereof
US2928770A (en) * 1958-11-28 1960-03-15 Frank M Bardani Sustained action pill
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
GB1346610A (de) * 1971-07-02 1974-02-13
GB1468172A (en) * 1973-03-28 1977-03-23 Benzon As Alfred Oral drug preparations
US3954959A (en) * 1973-03-28 1976-05-04 A/S Alfred Benzon Oral drug preparations
DE2802114A1 (de) * 1978-01-19 1979-07-26 Sandoz Ag Neue pharmazeutische zusammensetzung und verfahren zu deren herstellung
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
CH647676A5 (fr) * 1978-12-22 1985-02-15 Donald E Panoz Formes galeniques a usage oral, a liberation programmee et leurs procedes de preparation.
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
DE3124090A1 (de) * 1981-06-19 1983-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue orale dipyridamolformen
DE3126703A1 (de) * 1981-07-07 1983-01-27 Dr. Karl Thomae Gmbh, 7950 Biberach Bromhexin-retardform und verfahren zu ihrer herstellung
DE3237575A1 (de) * 1982-10-09 1984-04-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue orale mopidamolformen
IE55745B1 (en) * 1983-04-06 1991-01-02 Elan Corp Plc Sustained absorption pharmaceutical composition
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
IE56459B1 (en) * 1983-12-21 1991-08-14 Elan Corp Ltd Controlled absorption pharmaceutical formulation
IE56999B1 (en) * 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
US4894240A (en) * 1983-12-22 1990-01-16 Elan Corporation Plc Controlled absorption diltiazem formulation for once-daily administration
JPS615010A (ja) * 1984-06-18 1986-01-10 Tooa Eiyoo Kk 水素添加麦角アルカロイド徐放性製剤及びその製法
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
US4826688A (en) * 1985-11-13 1989-05-02 501 Elan Corporation PLC. Controlled absorption pharmaceutical formulation
DE3856555T2 (de) * 1987-10-16 2004-04-29 Elan Corp. Plc Diltiazem-Zusammensetzungen mit kontrollierter Wirkstoffabsorption
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
IL88083A (en) * 1987-11-06 1992-11-15 Tanabe Seiyaku Co Controlled release pharmaceutical dosage form and its preparation
FI101344B (fi) * 1988-03-31 1998-06-15 Tanabe Seiyaku Co Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseut tisesti aktiivista ainetta
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
JPH0674206B2 (ja) * 1989-12-28 1994-09-21 田辺製薬株式会社 放出制御型製剤およびその製法

Also Published As

Publication number Publication date
NZ242806A (en) 1994-01-26
WO1992020326A1 (en) 1992-11-26
ES2073301T3 (es) 1995-08-01
GR3015737T3 (en) 1995-07-31
JP3426230B2 (ja) 2003-07-14
DK0585355T3 (da) 1995-06-06
EP0585355B1 (de) 1995-03-22
AU2016992A (en) 1992-12-30
JPH06507903A (ja) 1994-09-08
EP0585355A1 (de) 1994-03-09
ATE120089T1 (de) 1995-04-15
DE69201793D1 (de) 1995-04-27
US5320853A (en) 1994-06-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMACEUTICALS INC.(N.D.GES.D.STAATES DEL

8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS HOLDINGS INC., GREENVILLE, DEL., US

Owner name: TANABE SEIYAKU CO., LTD., OSAKA, JP

8327 Change in the person/name/address of the patent owner

Owner name: AVENTISUB II INC., GREENVILLE, DEL., US

Owner name: TANABE SEIYAKU CO., LTD., OSAKA, JP

R071 Expiry of right

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