DE60237826D1 - Zusammensetzung enthaltend feine Körner mit verzögerter Freisetzung für in der Mundhöhle schnell zerfallende Tabletten - Google Patents

Zusammensetzung enthaltend feine Körner mit verzögerter Freisetzung für in der Mundhöhle schnell zerfallende Tabletten

Info

Publication number
DE60237826D1
DE60237826D1 DE60237826T DE60237826T DE60237826D1 DE 60237826 D1 DE60237826 D1 DE 60237826D1 DE 60237826 T DE60237826 T DE 60237826T DE 60237826 T DE60237826 T DE 60237826T DE 60237826 D1 DE60237826 D1 DE 60237826D1
Authority
DE
Germany
Prior art keywords
oral cavity
sustained
composition containing
containing fine
rapidly disintegrating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60237826T
Other languages
English (en)
Inventor
Tatsuki Shinoda
Atsushi Maeda
Naoki Itou
Takao Mizumoto
Shigeru Yamazaki
Yuuki Takaishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of DE60237826D1 publication Critical patent/DE60237826D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
DE60237826T 2001-07-27 2002-07-25 Zusammensetzung enthaltend feine Körner mit verzögerter Freisetzung für in der Mundhöhle schnell zerfallende Tabletten Expired - Lifetime DE60237826D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30830301P 2001-07-27 2001-07-27
PCT/JP2002/007550 WO2003009831A1 (en) 2001-07-27 2002-07-25 Compositions containing sustained-release fine grains for tablets quickly disintegrable in the oral cavity and process for producing the same

Publications (1)

Publication Number Publication Date
DE60237826D1 true DE60237826D1 (de) 2010-11-11

Family

ID=23193419

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60237826T Expired - Lifetime DE60237826D1 (de) 2001-07-27 2002-07-25 Zusammensetzung enthaltend feine Körner mit verzögerter Freisetzung für in der Mundhöhle schnell zerfallende Tabletten
DE20220604U Expired - Lifetime DE20220604U1 (de) 2001-07-27 2002-07-25 Zusammensetzung, enthaltend feine Partikel zur Langzeitfreisetzung für schnell in der Mundhöhle zerfallende Tabletten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE20220604U Expired - Lifetime DE20220604U1 (de) 2001-07-27 2002-07-25 Zusammensetzung, enthaltend feine Partikel zur Langzeitfreisetzung für schnell in der Mundhöhle zerfallende Tabletten

Country Status (18)

Country Link
US (2) US7255876B2 (de)
EP (1) EP1413294B1 (de)
JP (3) JP4019374B2 (de)
KR (1) KR100530546B1 (de)
CN (1) CN1473035B (de)
AT (1) ATE482692T1 (de)
AU (1) AU2002355222B2 (de)
BR (1) BR0205509A (de)
CA (1) CA2419089A1 (de)
CZ (1) CZ14921U1 (de)
DE (2) DE60237826D1 (de)
ES (1) ES2351249T3 (de)
HU (1) HUP0302351A3 (de)
MX (1) MXPA03000985A (de)
PL (1) PL361452A1 (de)
RU (1) RU2245136C2 (de)
WO (1) WO2003009831A1 (de)
ZA (1) ZA200300647B (de)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1128817A1 (de) * 1998-10-27 2001-09-05 Biovail Technologies Ltd Mikropartikel enthaltend peg und/oder peg glycerylestern
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
JP4019374B2 (ja) * 2001-07-27 2007-12-12 アステラス製薬株式会社 口腔内速崩壊錠用徐放性微粒子含有組成物およびその製造法
ES2256544T3 (es) * 2001-11-07 2006-07-16 Synthon B.V. Comprimidos de tamsulosina.
JP4173670B2 (ja) * 2002-03-08 2008-10-29 旭化成ファーマ株式会社 口腔内崩壊製剤
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE10244504A1 (de) * 2002-09-25 2004-04-08 Capsulution Nanoscience Ag Schnellfreisetzende Darreichungsform mit schwerlöslichem Wirkstoff
JP4523265B2 (ja) * 2002-11-13 2010-08-11 旭化成ファーマ株式会社 排尿障害治療用口腔内崩壊製剤
MXPA05009095A (es) * 2003-01-27 2006-05-19 Astellas Pharma Inc Particulas finas entericas de liberacion sostenida de tamsulosin o su sal y metodo de fabricacion de las mismas.
ZA200409537B (en) 2003-01-31 2006-10-25 Yamanouchi Pharma Co Ltd Stable solid medicinal composition for oral administration
ATE291419T1 (de) * 2003-04-30 2005-04-15 Ferring Bv Feste dosierungsform mit desmopressin
EP1479383B1 (de) * 2003-05-20 2006-10-04 Ethypharm Orale pharmazeutische Zusammensetzung mit verzögerter Freisetzung
WO2005013960A1 (en) * 2003-08-12 2005-02-17 Kyungdong Pharm. Co., Ltd. Preparing method for controlled released type tablet tamsulosin hcl and the tablet thereof
US20070122480A1 (en) * 2003-09-29 2007-05-31 Cj Corporation Sustained release formulations
CN100438914C (zh) * 2003-10-15 2008-12-03 富士化学工业株式会社 用于口腔内快速崩解的片剂的组合物
WO2005037254A1 (ja) * 2003-10-15 2005-04-28 Fuji Chemical Industry Co., Ltd. 口腔内速崩壊性錠剤
DE10350322A1 (de) * 2003-10-23 2005-06-09 Coty B.V. Klimabeständiger kosmetischer Komplex
JPWO2005039542A1 (ja) * 2003-10-27 2007-02-15 アステラス製薬株式会社 口腔内崩壊錠用の薬物含有被覆微粒子
US8197846B2 (en) * 2003-11-10 2012-06-12 Astellas Pharma Inc. Sustained release pharmaceutical composition
US8128958B2 (en) 2003-11-10 2012-03-06 Astellas Pharma Inc. Sustained release pharmaceutical composition
AU2003286415A1 (en) * 2003-12-03 2005-06-24 Natco Pharma Limited An improved pharmaceutical formulation containing tamsulosin salt and a process for its preparation
SI21637A (sl) * 2003-12-23 2005-06-30 LEK farmacevtska dru�ba d.d. Farmacevtska oblika z nadzorovanim sproščanjem
KR100582350B1 (ko) * 2004-02-17 2006-05-22 한미약품 주식회사 탐수로신 염산염의 경구투여용 조성물 및 이의 서방성과립 제제
ES2702608T3 (es) * 2004-06-10 2019-03-04 Glatt Air Techniques Inc Formulación de dosificación farmacéutica con matriz de liberación controlada
DE102004028940A1 (de) * 2004-06-15 2006-01-12 Krka Tovarna Zdravil, D.D. Oral zerfallende pharmazeutische Zusammensetzung, die Risperidon enthält
PT1618873E (pt) * 2004-07-14 2007-09-04 Siegfried Generics Int Ag Grânulos para libertação controlada de tamsulosina, que contém alginato.
PL204079B1 (pl) * 2004-08-12 2009-12-31 Inst Farmaceutyczny Stały doustny preparat chlorowodorku tamsulozyny o przedłużonym uwalnianiu i sposób jego wytwarzania
US8871273B2 (en) 2005-02-25 2014-10-28 Takeda Pharmaceutical Company Limited Method for producing granules
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
WO2006115285A1 (ja) * 2005-04-21 2006-11-02 Takeda Pharmaceutical Company Limited 医薬組成物
US20090023778A1 (en) * 2005-04-28 2009-01-22 Eisai R&D Management Co., Ltd. Composition Containing Anti-Dementia Drug
US20070048369A1 (en) * 2005-08-26 2007-03-01 National Starch And Chemical Investment Holding Corporation Mucosal delivery tablet
CA2620738C (en) * 2005-08-31 2010-10-12 Ezaki Glico Co., Ltd. Tablet for removing tongue coating
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
JP5365777B2 (ja) 2006-09-15 2013-12-11 アステラス製薬株式会社 光に対して安定なラモセトロンの固形医薬組成物
RU2465916C2 (ru) 2007-10-19 2012-11-10 Оцука Фармасьютикал Ко., Лтд. Твердый фармацевтический препарат матричного типа
EP2249803A2 (de) * 2008-02-13 2010-11-17 Bayer Schering Pharma Aktiengesellschaft Östradiol-haltiges arzneiabgabesystem
MX2010008945A (es) * 2008-02-13 2010-09-07 Bayer Schering Pharma Ag Sistema de administracion de drogas con efecto estabilizante.
JP5572321B2 (ja) * 2008-03-07 2014-08-13 沢井製薬株式会社 被覆微粒子含有口腔内崩壊錠
ES2332168B1 (es) * 2008-04-30 2010-10-27 Consejo Superior De Investigaciones Cientificas (Csic) (75%) Forma pseudopolimorfica de hidrocloruro de nicardipina, procedimiento para su preparacion y formulacion que la contiene.
WO2010001574A1 (ja) * 2008-07-01 2010-01-07 沢井製薬株式会社 タムスロシン塩酸塩を含有する球形微粒子の製造方法
CN101639340B (zh) * 2008-08-01 2011-01-12 广东省计量科学研究院 读数显微镜检定装置
CN102164588B (zh) 2008-09-24 2015-07-08 赢创罗姆有限公司 耐受乙醇影响的pH依赖性受控释放的药物组合物
EP2177215A1 (de) * 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-Kristalle von Tramadol und NSARs
EP2461811B1 (de) 2009-08-05 2016-04-20 Idenix Pharmaceuticals LLC. Makrocyclische serinproteasehemmer gegen virale infektionen, im besonderen hvc
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
KR20120056824A (ko) 2009-08-19 2012-06-04 바이엘 파마 악티엔게젤샤프트 소아과 용도를 위한 약물 전달 시스템 （웨이퍼）
TWI491395B (zh) 2009-09-30 2015-07-11 Ct Lab Inc 一種內含用以治療神經退化性疾病之立即釋出與長效釋出藥物的口服劑量配方
WO2011056764A1 (en) 2009-11-05 2011-05-12 Ambit Biosciences Corp. Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
BR112012014899A2 (pt) 2009-12-18 2017-03-14 Idenix Pharmaceuticals Inc composto, composição farmacêutica, método para tratar ou prevenir uma infecção por vírus de hepatite c em um sujeito, método para tratar , prevenir ou melhorar um ou mais sintomas de uma doença hepática ou distúrbio associado a uma infecção por vírus de hepatite c em um sujeito, método para inibir a replicação de um vírus em um hospedeiro, método para inibir a replicação de um vírus
WO2011094890A1 (en) 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
CA2792523C (en) * 2010-03-09 2018-01-09 Alkermes Pharma Ireland Limited Alcohol resistant enteric pharmaceutical compositions
WO2011112689A2 (en) 2010-03-11 2011-09-15 Ambit Biosciences Corp. Saltz of an indazolylpyrrolotriazine
JP5648303B2 (ja) * 2010-03-19 2015-01-07 味の素株式会社 耐吸湿固結性を有する粉体造粒物の製造方法および粉体造粒物
KR101423237B1 (ko) * 2010-05-04 2014-07-30 주식회사 삼양바이오팜 탐스로신 또는 이의 약학적으로 허용 가능한 염을 포함하는 방출 제어용 약학 조성물, 및 이를 포함하는 경구용 제제
JP5932794B2 (ja) 2010-09-01 2016-06-08 アムビト ビオスシエンセス コルポラチオン 光学活性のあるピラゾリルアミノキナゾリン及びその医薬組成物及び使用方法
US8633209B2 (en) 2010-09-01 2014-01-21 Ambit Biosciences Corporation Hydrobromide salts of a pyrazolylaminoquinazoline
JP2014500275A (ja) 2010-12-06 2014-01-09 フォリカ，インコーポレイテッド 禿頭症を治療するため、および毛髪の成長を促進するための方法
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
KR101111534B1 (ko) * 2010-12-24 2012-02-15 (주)비씨월드제약 구강 속붕해성 조성물 및 이의 제조방법
US9393255B2 (en) 2011-01-31 2016-07-19 Celgene Corporation Pharmaceutical compositions of cytidine analogs and methods of use thereof
WO2012109398A1 (en) 2011-02-10 2012-08-16 Idenix Pharmaceuticals, Inc. Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating hcv infections
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
WO2013019056A1 (en) * 2011-08-01 2013-02-07 Sam-A Pharm. Co., Ltd. Novel granule formulation containing sildenafil or pharmaceutically acceptable salts thereof as an active ingredient
JP6195848B2 (ja) 2012-01-27 2017-09-13 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ 糖ポリマーを用いた生体分子の安定化
SG10201507714XA (en) 2012-03-16 2015-10-29 Axikin Pharmaceuticals Inc 3,5-diaminopyrazole kinase inhibitors
KR101778050B1 (ko) * 2012-10-12 2017-09-13 이에이 파마 가부시키가이샤 칼슘 길항약／안지오텐신 ｉｉ 수용체 길항약 함유 의약 제제의 제조 방법
EP2919903B1 (de) 2012-11-14 2020-07-22 W.R. Grace & CO. - CONN. Zusammensetzungen mit einem biologischen wirkstoff und einem nicht geordneten anorganischen oxid
CN103230379A (zh) * 2013-04-02 2013-08-07 万特制药(海南)有限公司 一种含有盐酸坦索罗辛的口崩缓释制剂及其制备方法
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
WO2015042375A1 (en) 2013-09-20 2015-03-26 Idenix Pharmaceuticals, Inc. Hepatitis c virus inhibitors
EP3114122A1 (de) 2014-03-05 2017-01-11 Idenix Pharmaceuticals LLC Feste formen einer flaviviridae-virus-hemmerverbindung und salze davon
DK3119762T3 (da) 2014-03-20 2021-08-30 Capella Therapeutics Inc Benzimidazol-derivater som erbb-tyrosin-kinase-inhibitorer til behandlingen af kræft
CN106661027B (zh) 2014-03-20 2019-12-24 卡佩拉医疗公司 苯并咪唑衍生物作为erbb酪氨酸激酶抑制剂用于治疗癌症
US10335374B2 (en) * 2014-12-04 2019-07-02 University System of Georgia, Valdosta State University Tablet composition for anti-tuberculosis antibiotics
ES2805528T3 (es) 2014-12-23 2021-02-12 Sma Therapeutics Inc Inhibidores de 3,5-diaminopirazol quinasa
CZ2015225A3 (cs) * 2015-03-30 2016-10-12 Zentiva, K.S. Nový krok ve způsobu potahování pelet obsahujících Tamsulosin.HCI
JP2016193894A (ja) * 2015-04-01 2016-11-17 京都薬品工業株式会社 生菌含有製剤
JP6618736B2 (ja) * 2015-09-01 2019-12-11 沢井製薬株式会社 ミラベグロン含有錠剤、ミラベグロン含有製剤の製造方法及びミラベグロン含有造粒物の製造方法
IL261756B2 (en) 2016-03-17 2023-11-01 Thiogenesis Therapeutics Inc Preparations for the controlled release of cysteamine and systemic treatment of disorders sensitive to cysteamine
CN108066347B (zh) * 2016-11-16 2021-02-02 深圳万和制药有限公司 包含坦索罗辛和度他雄胺的口腔崩解片药物组合物
CN107616969B (zh) * 2016-11-16 2020-09-18 杭州朱养心药业有限公司 迅速崩解的吡仑帕奈片剂药物组合物
CN108066304B (zh) * 2016-11-16 2022-09-16 深圳万和制药有限公司 具有缓释性能的坦索罗辛口腔崩解片组合物
CN108066297B (zh) * 2016-11-16 2022-09-16 深圳万和制药有限公司 治疗老年痴呆症的定位释放美金刚口腔崩解片组合物
CN108066305B (zh) * 2016-11-16 2022-09-16 深圳万和制药有限公司 改善口崩片硬度和崩解的方法和定位释放口腔崩解片
JP7182550B2 (ja) 2017-08-21 2022-12-02 ニプロ株式会社 医薬組成物粒子とそれを含む口腔内崩壊製剤、医薬組成物粒子の製造方法
JP7336388B2 (ja) * 2018-02-02 2023-08-31 ニプロ株式会社 錠剤及びその製造方法
EP3768240A4 (de) * 2018-03-19 2021-12-22 Cage Bio Inc. Ionische flüssige zusammensetzungen zur behandlung von rosacea
GB202001237D0 (en) * 2020-01-29 2020-03-11 Sisteks D O O Granular pharmaceutical product for oral administration from a pre-filled straw and method of manufacturing such pharmaceutical product

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation
JPH0780754B2 (ja) 1986-08-06 1995-08-30 エーザイ株式会社 多顆粒型持続性錠剤
JPH01135451A (ja) * 1987-11-20 1989-05-29 Mitsubishi Electric Corp 搬送ロボット
DE69023654T2 (de) * 1989-08-25 1996-04-18 Bioglan Ireland R & D Ltd Pharmazeutische zusammensetzung und einnahmevorrichtung dafür.
DE69122280T2 (de) 1990-03-01 1997-04-24 Hewlett Packard Co Minimierung von Eluatbandbreiten in der Flüssigchromatographie
EP0447168A3 (en) * 1990-03-16 1993-01-07 Yamanouchi Pharmaceutical Co. Ltd. Long acting granular pharmaceutical composition
WO1993012769A1 (en) * 1991-12-24 1993-07-08 Yamanouchi Pharmaceutical Co., Ltd. Intrabuccally disintegrating preparation and production thereof
US5576014A (en) 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
EP0745382B1 (de) * 1994-01-31 2003-11-12 Yamanouchi Pharmaceutical Co. Ltd. Intraoral löslicher formpressling und verfahren zu seiner herstellung
JPH1135451A (ja) 1994-07-27 1999-02-09 Yamanouchi Pharmaceut Co Ltd 口腔内溶解型錠剤およびその製造方法
US5824339A (en) * 1995-09-08 1998-10-20 Takeda Chemical Industries, Ltd Effervescent composition and its production
BR9710265A (pt) 1996-07-12 1999-08-10 Daiichi Seiyaku Co Materiais moldados á compressão rapidamente desintegráveis e processo para produção dos mesmos
JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
ATE323467T1 (de) * 1997-07-25 2006-05-15 Alpex Pharma Sa Verfahren zur herstellung eines granulates, geeignet zur herstellung schnell-freisetzender, im mund löslicher tabletten
NZ505123A (en) * 1997-12-19 2003-07-25 Smithkline Beecham Corp Process for manufacturing bite-dispersion tablets by compressing medicaments and other ingredients into granulates then compressing the granulates and other ingredients into tablets, and the tablets thereof
NZ506903A (en) 1998-03-16 2003-01-31 Yamanouchi Pharma Tech Inc Tablets quickly disintegrating in the oral cavity and process for producing the same
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
JP2000128774A (ja) 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
US6495177B1 (en) * 1999-08-13 2002-12-17 Warner Chilcott Laboratories Ireland Limited Orally dissolvable nutritional supplement
US20030104066A1 (en) 2000-03-27 2003-06-05 Kouji Murai Easy-to-take granules
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
JP4019374B2 (ja) * 2001-07-27 2007-12-12 アステラス製薬株式会社 口腔内速崩壊錠用徐放性微粒子含有組成物およびその製造法

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CN1473035B (zh) 2012-07-18
JPWO2003009831A1 (ja) 2004-11-11
EP1413294A4 (de) 2006-06-07
HUP0302351A3 (en) 2007-03-28
HUP0302351A2 (hu) 2003-10-28
US7255876B2 (en) 2007-08-14
RU2245136C2 (ru) 2005-01-27
JP4019374B2 (ja) 2007-12-12
KR100530546B1 (ko) 2005-11-23
WO2003009831A1 (en) 2003-02-06
DE20220604U1 (de) 2004-02-26
EP1413294B1 (de) 2010-09-29
JP2004196829A (ja) 2004-07-15
MXPA03000985A (es) 2004-04-02
ZA200300647B (en) 2004-07-14
KR20030036656A (ko) 2003-05-09
CN1473035A (zh) 2004-02-04
ES2351249T3 (es) 2011-02-02
EP1413294A1 (de) 2004-04-28
CA2419089A1 (en) 2003-03-05
PL361452A1 (en) 2004-10-04
AU2002355222B2 (en) 2007-07-26
CZ14921U1 (cs) 2004-11-23
ATE482692T1 (de) 2010-10-15
US20070202168A1 (en) 2007-08-30
JP2005206608A (ja) 2005-08-04
BR0205509A (pt) 2003-06-24
US20030147948A1 (en) 2003-08-07

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