MX2009004439A - Composicion de ibuprofeno. - Google Patents
Composicion de ibuprofeno.Info
- Publication number
- MX2009004439A MX2009004439A MX2009004439A MX2009004439A MX2009004439A MX 2009004439 A MX2009004439 A MX 2009004439A MX 2009004439 A MX2009004439 A MX 2009004439A MX 2009004439 A MX2009004439 A MX 2009004439A MX 2009004439 A MX2009004439 A MX 2009004439A
- Authority
- MX
- Mexico
- Prior art keywords
- water
- soluble acid
- ibuprofen composition
- ibuprofen
- water soluble
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Abstract
La invención se refiere a una tableta de liberación inmediata capaz de ser masticada o desintegrada en la cavidad oral, que comprende una pluralidad de partículas en una matriz; las partículas contienen un ingrediente activo, tal como ibuprofeno, y un primer ácido soluble en agua que tiene una solubilidad mayor que aproximadamente 10 g/100 ml de agua a 20°C; y la matriz contiene un segundo ácido soluble en agua que tiene una solubilidad menor que aproximadamente 5 g/100 ml de agua a 20°C.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85434906P | 2006-10-25 | 2006-10-25 | |
PCT/US2007/082348 WO2008052033A2 (en) | 2006-10-25 | 2007-10-24 | Ibuprofen composition |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009004439A true MX2009004439A (es) | 2009-05-11 |
Family
ID=39223093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009004439A MX2009004439A (es) | 2006-10-25 | 2007-10-24 | Composicion de ibuprofeno. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20080113021A1 (es) |
EP (1) | EP2094248A2 (es) |
CN (1) | CN101528205A (es) |
AU (1) | AU2007308986A1 (es) |
BR (1) | BRPI0718428A2 (es) |
CA (1) | CA2667207A1 (es) |
MX (1) | MX2009004439A (es) |
WO (1) | WO2008052033A2 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2853262T3 (en) | 2009-10-26 | 2017-03-06 | Sephoris Pharmaceuticals Llc | Treatment of sunburn using analgesics and antihistamines |
WO2012056471A2 (en) * | 2010-10-24 | 2012-05-03 | Shasun Pharmaceuticals Limited | Novel process for preparing dexibuprofen ready to compress granules |
CN102258490B (zh) * | 2011-07-01 | 2012-10-03 | 中美天津史克制药有限公司 | 布洛芬咀嚼片 |
JP6122427B2 (ja) | 2011-07-07 | 2017-04-26 | ヤンセン・サイエンシズ・アイルランド・ユーシー | ダルナビル複合製剤 |
CN102488681B (zh) * | 2011-12-21 | 2013-03-13 | 西南大学 | 布洛芬苯海拉明口腔崩解片及其制备方法 |
CA2884119A1 (en) | 2012-09-18 | 2014-03-27 | Mcneil-Ppc, Inc. | Low melting propionic acid derivative particles for use in oral dosage forms |
RU2015114433A (ru) * | 2012-09-18 | 2016-11-10 | МакНЕЙЛ-ППС, ИНК. | Пероральные дозированные формы с замедленным высвобождением, содержащие частицы легкоплавкого производного пропионовой кислоты |
ES2946985T3 (es) * | 2013-03-14 | 2023-07-31 | Redhill Biopharma Ltd | Formas farmacéuticas sólidas antieméticas de liberación prolongada |
WO2015136377A2 (en) | 2014-03-11 | 2015-09-17 | Redhill Biopharma Ltd. | Ondansetron extended release solid dosage forms for treating either nausea, vomiting or diarrhea symptoms |
WO2015157729A1 (en) * | 2014-04-11 | 2015-10-15 | Wilmink Michael | Pharmaceutical formulations an comprising analgesic agent, a nonsteroidal anti-inflammatory agent, a gastric acid production suppressant and an anti-nauseant |
ES2926494T3 (es) | 2015-03-26 | 2022-10-26 | Sen Jam Pharmaceutical Llc | Combinación de naproxeno y fexofenadina para inhibir los síntomas asociados con veisalgia |
RU2744270C2 (ru) * | 2015-12-28 | 2021-03-04 | ЭсЭсПи КО., ЛТД., ДЖАПАН | Прессованный фармацевтический препарат |
CN111035764B (zh) * | 2018-10-14 | 2021-09-07 | 深圳市健元医药科技有限公司 | 一种治疗类风湿性关节炎的组合物及其制备方法 |
TW202045153A (zh) | 2019-02-22 | 2020-12-16 | 英商康泰倫特英國斯文敦載迪斯有限公司 | 含伊布洛芬之醫藥組合物之塗層之黏聚最小化、通氣及保存 |
CA3129434A1 (en) | 2019-02-22 | 2020-08-27 | Catalent U.K. Swindon Zydis Limited | Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products |
HUE064524T2 (hu) * | 2019-02-22 | 2024-03-28 | Catalent Uk Swindon Zydis Ltd | Szuszpenziók aerálódásának minimalizálása in-line keverés során |
MX2021009844A (es) | 2019-02-22 | 2021-09-10 | Catalent Uk Swindon Zydis Ltd | Conservacion de particulas de ingredientes farmaceuticos activos revestidas funcionalmente producidas mediante procesos de mezcla sin solvente en suspension acuosa. |
Family Cites Families (32)
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JPS54127247A (en) * | 1978-03-27 | 1979-10-03 | Toshiba Corp | Microprogram controller |
US4543370A (en) * | 1979-11-29 | 1985-09-24 | Colorcon, Inc. | Dry edible film coating composition, method and coating form |
US4683256A (en) * | 1980-11-06 | 1987-07-28 | Colorcon, Inc. | Dry edible film coating composition, method and coating form |
US4643894A (en) * | 1984-07-24 | 1987-02-17 | Colorcon, Inc. | Maltodextrin coating |
US4828841A (en) * | 1984-07-24 | 1989-05-09 | Colorcon, Inc. | Maltodextrin coating |
DE3440288A1 (de) * | 1984-11-05 | 1986-05-07 | Gergely, Gerhard, Dr.-Ing., Wien | Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung |
US4802924A (en) * | 1986-06-19 | 1989-02-07 | Colorcon, Inc. | Coatings based on polydextrose for aqueous film coating of pharmaceutical food and confectionary products |
US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
US4867983A (en) * | 1987-02-20 | 1989-09-19 | Mcneilab, Inc. | Method for double dipping gelating coated caplets |
US4966771A (en) * | 1987-02-20 | 1990-10-30 | Mcneilab, Inc. | Gelatin coated caplets and process for making same |
US4820524A (en) * | 1987-02-20 | 1989-04-11 | Mcneilab, Inc. | Gelatin coated caplets and process for making same |
US4906478A (en) * | 1988-12-12 | 1990-03-06 | Valentine Enterprises, Inc. | Simethicone/calcium silicate composition |
US5275822A (en) * | 1989-10-19 | 1994-01-04 | Valentine Enterprises, Inc. | Defoaming composition |
IT1246383B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per il mascheramento del sapore di farmaci |
US5089270A (en) * | 1990-05-15 | 1992-02-18 | L. Perrigo Company | Capsule-shaped tablet |
US5213738A (en) * | 1990-05-15 | 1993-05-25 | L. Perrigo Company | Method for making a capsule-shaped tablet |
US5409709A (en) * | 1991-11-29 | 1995-04-25 | Lion Corporation | Antipyretic analgesic preparation containing ibuprofen |
AU674840B2 (en) * | 1992-01-17 | 1997-01-16 | Bpsi Holdings, Inc. | Film coatings and film coating compositions based on cellulosic polymers and lactose |
US5466865A (en) * | 1993-07-02 | 1995-11-14 | Ibah, Inc. | Neomorphic ibuprofen and methods of using same |
US6103260A (en) * | 1997-07-17 | 2000-08-15 | Mcneil-Ppc, Inc. | Simethicone/anhydrous calcium phosphate compositions |
NZ333474A (en) * | 1998-01-02 | 1999-06-29 | Mcneil Ppc Inc | A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat |
US6274162B1 (en) * | 2000-01-14 | 2001-08-14 | Bpsi Holdings, Inc. | Elegant film coating system |
US7223421B2 (en) * | 2000-06-30 | 2007-05-29 | Mcneil-Ppc, Inc. | Teste masked pharmaceutical particles |
US6440983B1 (en) * | 2000-12-21 | 2002-08-27 | Mary Theresa Frank-Kollman | Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers |
AU2002244865A1 (en) * | 2001-03-02 | 2002-09-19 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical composition of ibuprofen |
GB0113843D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
US6982094B2 (en) * | 2001-09-28 | 2006-01-03 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
US7323192B2 (en) * | 2001-09-28 | 2008-01-29 | Mcneil-Ppc, Inc. | Immediate release tablet |
US7122143B2 (en) * | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
BR0206062A (pt) * | 2001-09-28 | 2004-01-13 | Mcneil Ppc Inc | Formas de dosagem tendo um núcleo interno e invólucro externo |
US7807197B2 (en) * | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
AU2006312119B2 (en) * | 2005-11-02 | 2010-04-29 | Teikoku Pharma Usa, Inc. | Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same |
-
2007
- 2007-10-24 CN CNA2007800396083A patent/CN101528205A/zh active Pending
- 2007-10-24 BR BRPI0718428-0A2A patent/BRPI0718428A2/pt not_active Application Discontinuation
- 2007-10-24 WO PCT/US2007/082348 patent/WO2008052033A2/en active Application Filing
- 2007-10-24 CA CA002667207A patent/CA2667207A1/en not_active Abandoned
- 2007-10-24 AU AU2007308986A patent/AU2007308986A1/en not_active Abandoned
- 2007-10-24 MX MX2009004439A patent/MX2009004439A/es not_active Application Discontinuation
- 2007-10-24 US US11/877,917 patent/US20080113021A1/en not_active Abandoned
- 2007-10-24 EP EP07844565A patent/EP2094248A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US20080113021A1 (en) | 2008-05-15 |
AU2007308986A1 (en) | 2008-05-02 |
CA2667207A1 (en) | 2008-05-02 |
EP2094248A2 (en) | 2009-09-02 |
BRPI0718428A2 (pt) | 2013-11-12 |
WO2008052033A3 (en) | 2008-06-12 |
CN101528205A (zh) | 2009-09-09 |
WO2008052033A2 (en) | 2008-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |