DE60232276D1 - Alpha-(n-sulfonamid)acetamidderivate als beta-amyloidinhibitoren - Google Patents

Alpha-(n-sulfonamid)acetamidderivate als beta-amyloidinhibitoren

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Publication number
DE60232276D1
DE60232276D1 DE60232276T DE60232276T DE60232276D1 DE 60232276 D1 DE60232276 D1 DE 60232276D1 DE 60232276 T DE60232276 T DE 60232276T DE 60232276 T DE60232276 T DE 60232276T DE 60232276 D1 DE60232276 D1 DE 60232276D1
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Germany
Prior art keywords
beta
alpha
amyloidinhibitors
sulfonamide
acetamide derivatives
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Expired - Lifetime
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DE60232276T
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English (en)
Inventor
Michael F Parker
Katharine E Mcelhone
Robert A Mate
Joanne J Bronson
Yonghua Gai
Carl P Bergstrom
Lawrence R Marcin
John E Macor
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/18—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
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DE60232276T 2001-12-20 2002-12-20 Alpha-(n-sulfonamid)acetamidderivate als beta-amyloidinhibitoren Expired - Lifetime DE60232276D1 (de)

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US20040127494A1 (en) 2004-07-01
US8513253B2 (en) 2013-08-20
PL204281B1 (pl) 2009-12-31
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JP2005513123A (ja) 2005-05-12
IL162498A (en) 2010-06-16
US20110105485A1 (en) 2011-05-05
HUP0500173A2 (hu) 2005-05-30
PT1465861E (pt) 2009-07-08
GEP20063920B (en) 2006-09-11
JP2009102435A (ja) 2009-05-14
HK1067963A1 (en) 2005-04-22
ZA200404811B (en) 2006-02-22
CA2471099A1 (en) 2003-07-03
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AU2002357333A1 (en) 2003-07-09
EP1465861A4 (de) 2005-12-07
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US7300936B2 (en) 2007-11-27
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CO5590894A2 (es) 2005-12-30
AU2002357333B2 (en) 2008-02-28
JP4287746B2 (ja) 2009-07-01
DK1465861T3 (da) 2009-08-31
KR20040068957A (ko) 2004-08-02
CA2471099C (en) 2011-04-12
WO2003053912A1 (en) 2003-07-03
EP1465861B1 (de) 2009-05-06
KR100966705B1 (ko) 2010-06-29
CN1617852A (zh) 2005-05-18
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