PT1465861E - Derivados de α-(n-sulfonamido)-acetamida como inibidores β-amilóides - Google Patents

Derivados de α-(n-sulfonamido)-acetamida como inibidores β-amilóides Download PDF

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PT1465861E
PT1465861E PT02805633T PT02805633T PT1465861E PT 1465861 E PT1465861 E PT 1465861E PT 02805633 T PT02805633 T PT 02805633T PT 02805633 T PT02805633 T PT 02805633T PT 1465861 E PT1465861 E PT 1465861E
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Prior art keywords
beta
alpha
sulphonamido
acetamide derivatives
amyloid inhibitors
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PT02805633T
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English (en)
Inventor
Michael F Parker
Katharine E Mcelhone
Robert A Mate
Joanne J Bronson
Yonghua Gai
Carl P Bergstrom
Lawrence R Marcin
John E Macor
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Bristol Myers Squibb Co
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Publication of PT1465861E publication Critical patent/PT1465861E/pt

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    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/18Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
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    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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PT02805633T 2001-12-20 2002-12-20 Derivados de α-(n-sulfonamido)-acetamida como inibidores β-amilóides PT1465861E (pt)

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US20040127494A1 (en) 2004-07-01
NO328976B1 (no) 2010-07-05
DK1465861T3 (da) 2009-08-31
JP2005513123A (ja) 2005-05-12
RU2300518C2 (ru) 2007-06-10
IS2879B (is) 2014-04-15
ZA200404811B (en) 2006-02-22
UA78537C2 (en) 2007-04-10
NZ533603A (en) 2007-02-23
PL204281B1 (pl) 2009-12-31
JP4287746B2 (ja) 2009-07-01
HK1067963A1 (en) 2005-04-22
RU2004122481A (ru) 2006-01-20
US20080085894A1 (en) 2008-04-10
RS51155B (sr) 2010-10-31
CN1617852A (zh) 2005-05-18
US7786122B2 (en) 2010-08-31
BR0215182A (pt) 2004-10-19
US7300936B2 (en) 2007-11-27
NO20043098L (no) 2004-09-01
IS7325A (is) 2004-06-18
MXPA04005927A (es) 2004-11-01
US8513253B2 (en) 2013-08-20
PL371046A1 (en) 2005-06-13
KR100966705B1 (ko) 2010-06-29
EP1465861B1 (en) 2009-05-06
ES2325205T3 (es) 2009-08-28
HRP20040566A2 (en) 2004-10-31
HUP0500173A2 (hu) 2005-05-30
JP5030982B2 (ja) 2012-09-19
WO2003053912A1 (en) 2003-07-03
CN1289469C (zh) 2006-12-13
AU2002357333B2 (en) 2008-02-28
CO5590894A2 (es) 2005-12-30
IL162498A (en) 2010-06-16
CA2471099C (en) 2011-04-12
CY1109275T1 (el) 2014-07-02
EP1465861A1 (en) 2004-10-13
RS53704A (en) 2006-12-15
HUP0500173A3 (en) 2009-03-30
SI1465861T1 (sl) 2009-12-31
KR20040068957A (ko) 2004-08-02
ATE430727T1 (de) 2009-05-15
JP2009102435A (ja) 2009-05-14
EP1465861A4 (en) 2005-12-07
GEP20063920B (en) 2006-09-11
AU2002357333A1 (en) 2003-07-09
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