DE60214713T2 - Arylborsäuren für die behandlung von fettsucht - Google Patents
Arylborsäuren für die behandlung von fettsucht Download PDFInfo
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- DE60214713T2 DE60214713T2 DE60214713T DE60214713T DE60214713T2 DE 60214713 T2 DE60214713 T2 DE 60214713T2 DE 60214713 T DE60214713 T DE 60214713T DE 60214713 T DE60214713 T DE 60214713T DE 60214713 T2 DE60214713 T2 DE 60214713T2
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- substituted
- amine
- ammonium
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- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 34
- -1 phenyl boronic acid compound Chemical class 0.000 claims abstract description 32
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 31
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract description 24
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- 125000000217 alkyl group Chemical group 0.000 claims abstract description 14
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- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
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- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30208101P | 2001-06-29 | 2001-06-29 | |
| US302081P | 2001-06-29 | ||
| US35946702P | 2002-02-22 | 2002-02-22 | |
| US359467P | 2002-02-22 | ||
| PCT/US2002/020923 WO2003002570A1 (en) | 2001-06-29 | 2002-07-01 | Aryl boronic acids for treating obesity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60214713D1 DE60214713D1 (de) | 2006-10-26 |
| DE60214713T2 true DE60214713T2 (de) | 2007-09-06 |
Family
ID=26972758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60214713T Expired - Fee Related DE60214713T2 (de) | 2001-06-29 | 2002-07-01 | Arylborsäuren für die behandlung von fettsucht |
Country Status (12)
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|---|---|
| US (3) | US6858592B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1404685B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2004535452A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE339426T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2002316499B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2489681A1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1105829T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60214713T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1404685T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2275888T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1404685E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003002570A1 (cg-RX-API-DMAC7.html) |
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| AU2003291567A1 (en) * | 2002-11-19 | 2004-06-15 | Genzyme Corporation | Polymeric boronic acid derivatives as lipase inhibitors |
| AU2005304318A1 (en) * | 2004-11-12 | 2006-05-18 | Trustees Of Tufts College | Lipase inhibitors |
| US7696347B2 (en) * | 2005-03-14 | 2010-04-13 | Eisai R&D Management Co., Ltd. | Oxymethyl boron compounds |
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| WO2009012596A1 (en) * | 2007-07-24 | 2009-01-29 | The University Of British Columbia | Substituted aryl-fluoroborates as imaging agents |
| AU2009233711B2 (en) * | 2008-04-09 | 2015-02-12 | Infinity Pharmaceuticals, Inc | Inhibitors of fatty acid amide hydrolase |
| WO2010118155A1 (en) | 2009-04-07 | 2010-10-14 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| WO2010118159A1 (en) | 2009-04-07 | 2010-10-14 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| US8709489B2 (en) | 2009-09-30 | 2014-04-29 | Surmodics, Inc. | Emulsions containing arylboronic acids and medical articles made therefrom |
| BR112012019120A2 (pt) | 2010-02-03 | 2016-06-28 | Infinity Pharmaceuticais Inc | forma sólida, composição farmacêutica, método de preparação do composto 1, método de tratamento de uma condição mediada por faah |
| US8546617B1 (en) | 2012-03-23 | 2013-10-01 | Empire Technology Development Llc | Dioxaborinanes and uses thereof |
| WO2014021845A1 (en) * | 2012-07-31 | 2014-02-06 | Empire Technology Development Llc | Polymerizable organoboron alkyd resin anti fouling coatings |
| WO2014062794A1 (en) * | 2012-10-17 | 2014-04-24 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for improving glucose uptake |
| CA2903281C (en) | 2013-03-08 | 2022-11-29 | The University Of British Columbia | Substituted organofluoroborates as imaging agents |
| EP3913068B1 (en) | 2015-10-12 | 2023-08-02 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
| CN106243343B (zh) * | 2016-08-11 | 2018-04-03 | 江苏大学 | 一种苯硼酸功能化嵌段聚合物的合成及应用 |
| CA3118223A1 (en) | 2018-12-18 | 2020-06-25 | Provincial Health Services Authority | Dual mode 18f-labelled theranostic compounds and uses thereof |
| WO2022082312A1 (en) | 2020-10-21 | 2022-04-28 | Provincial Health Services Authority | Novel cxcr4-targeting compounds |
| EP4313033A4 (en) * | 2021-03-24 | 2025-04-23 | Trustees Of Tufts College | BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS |
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-
2002
- 2002-06-27 US US10/187,397 patent/US6858592B2/en not_active Expired - Lifetime
- 2002-07-01 AU AU2002316499A patent/AU2002316499B2/en not_active Ceased
- 2002-07-01 EP EP02746808A patent/EP1404685B1/en not_active Expired - Lifetime
- 2002-07-01 WO PCT/US2002/020923 patent/WO2003002570A1/en not_active Ceased
- 2002-07-01 AT AT02746808T patent/ATE339426T1/de not_active IP Right Cessation
- 2002-07-01 PT PT02746808T patent/PT1404685E/pt unknown
- 2002-07-01 DK DK02746808T patent/DK1404685T3/da active
- 2002-07-01 ES ES02746808T patent/ES2275888T3/es not_active Expired - Lifetime
- 2002-07-01 CA CA002489681A patent/CA2489681A1/en not_active Abandoned
- 2002-07-01 JP JP2003508951A patent/JP2004535452A/ja active Pending
- 2002-07-01 DE DE60214713T patent/DE60214713T2/de not_active Expired - Fee Related
-
2004
- 2004-12-30 US US11/027,643 patent/US7049304B2/en not_active Expired - Lifetime
-
2005
- 2005-10-05 AU AU2005220192A patent/AU2005220192A1/en not_active Abandoned
-
2006
- 2006-01-31 US US11/343,598 patent/US7456156B2/en not_active Expired - Fee Related
- 2006-12-05 CY CY20061101748T patent/CY1105829T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20050107336A1 (en) | 2005-05-19 |
| WO2003002570A1 (en) | 2003-01-09 |
| CA2489681A1 (en) | 2003-01-09 |
| US6858592B2 (en) | 2005-02-22 |
| EP1404685A1 (en) | 2004-04-07 |
| DE60214713D1 (de) | 2006-10-26 |
| US20060128664A1 (en) | 2006-06-15 |
| HK1065046A1 (en) | 2005-02-08 |
| US7049304B2 (en) | 2006-05-23 |
| CY1105829T1 (el) | 2011-02-02 |
| ATE339426T1 (de) | 2006-10-15 |
| ES2275888T3 (es) | 2007-06-16 |
| AU2005220192A1 (en) | 2005-12-01 |
| EP1404685B1 (en) | 2006-09-13 |
| AU2002316499B2 (en) | 2005-08-04 |
| US20030064963A1 (en) | 2003-04-03 |
| DK1404685T3 (da) | 2007-01-22 |
| JP2004535452A (ja) | 2004-11-25 |
| PT1404685E (pt) | 2007-01-31 |
| US7456156B2 (en) | 2008-11-25 |
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