AU2002316499B2 - Aryl boronic acids for treating obesity - Google Patents

Aryl boronic acids for treating obesity Download PDF

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Publication number
AU2002316499B2
AU2002316499B2 AU2002316499A AU2002316499A AU2002316499B2 AU 2002316499 B2 AU2002316499 B2 AU 2002316499B2 AU 2002316499 A AU2002316499 A AU 2002316499A AU 2002316499 A AU2002316499 A AU 2002316499A AU 2002316499 B2 AU2002316499 B2 AU 2002316499B2
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AU
Australia
Prior art keywords
group
substituted
sub
straight chained
compound
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002316499A
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English (en)
Other versions
AU2002316499A1 (en
Inventor
Pradeep K. Dhal
Stephen Randall Holmes-Farley
Chad Cori Huval
Xinhua Li
W. Harry Mandeville Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of AU2002316499A1 publication Critical patent/AU2002316499A1/en
Assigned to GENZYME CORPORATION reassignment GENZYME CORPORATION Amend patent request/document other than specification (104) Assignors: GELTEX PHARMACEUTICALS, INC.
Application granted granted Critical
Publication of AU2002316499B2 publication Critical patent/AU2002316499B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2002316499A 2001-06-29 2002-07-01 Aryl boronic acids for treating obesity Ceased AU2002316499B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30208101P 2001-06-29 2001-06-29
US60/302,081 2001-06-29
US35946702P 2002-02-22 2002-02-22
US60/359,467 2002-02-22
PCT/US2002/020923 WO2003002570A1 (en) 2001-06-29 2002-07-01 Aryl boronic acids for treating obesity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2005220192A Division AU2005220192A1 (en) 2001-06-29 2005-10-05 Aryl boronic acids for treating obesity

Publications (2)

Publication Number Publication Date
AU2002316499A1 AU2002316499A1 (en) 2003-05-15
AU2002316499B2 true AU2002316499B2 (en) 2005-08-04

Family

ID=26972758

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2002316499A Ceased AU2002316499B2 (en) 2001-06-29 2002-07-01 Aryl boronic acids for treating obesity
AU2005220192A Abandoned AU2005220192A1 (en) 2001-06-29 2005-10-05 Aryl boronic acids for treating obesity

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2005220192A Abandoned AU2005220192A1 (en) 2001-06-29 2005-10-05 Aryl boronic acids for treating obesity

Country Status (12)

Country Link
US (3) US6858592B2 (cg-RX-API-DMAC7.html)
EP (1) EP1404685B1 (cg-RX-API-DMAC7.html)
JP (1) JP2004535452A (cg-RX-API-DMAC7.html)
AT (1) ATE339426T1 (cg-RX-API-DMAC7.html)
AU (2) AU2002316499B2 (cg-RX-API-DMAC7.html)
CA (1) CA2489681A1 (cg-RX-API-DMAC7.html)
CY (1) CY1105829T1 (cg-RX-API-DMAC7.html)
DE (1) DE60214713T2 (cg-RX-API-DMAC7.html)
DK (1) DK1404685T3 (cg-RX-API-DMAC7.html)
ES (1) ES2275888T3 (cg-RX-API-DMAC7.html)
PT (1) PT1404685E (cg-RX-API-DMAC7.html)
WO (1) WO2003002570A1 (cg-RX-API-DMAC7.html)

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US6858592B2 (en) * 2001-06-29 2005-02-22 Genzyme Corporation Aryl boronic acids for treating obesity
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
AU2003223930A1 (en) * 2002-06-14 2003-12-31 Novo Nordisk A/S Pharmaceutical use of boronic acids and esters thereof
AU2003291567A1 (en) * 2002-11-19 2004-06-15 Genzyme Corporation Polymeric boronic acid derivatives as lipase inhibitors
AU2005304318A1 (en) * 2004-11-12 2006-05-18 Trustees Of Tufts College Lipase inhibitors
US7696347B2 (en) * 2005-03-14 2010-04-13 Eisai R&D Management Co., Ltd. Oxymethyl boron compounds
US7622492B2 (en) 2005-08-31 2009-11-24 Hoffmann-La Roche Inc. Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase
US10157355B2 (en) 2005-11-15 2018-12-18 General Electric Company Method to view schedule interdependencies and provide proactive clinical process decision support in day view form
US7801058B2 (en) * 2006-07-27 2010-09-21 Mobitrum Corporation Method and system for dynamic information exchange on mesh network devices
JO3598B1 (ar) 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
WO2009012596A1 (en) * 2007-07-24 2009-01-29 The University Of British Columbia Substituted aryl-fluoroborates as imaging agents
AU2009233711B2 (en) * 2008-04-09 2015-02-12 Infinity Pharmaceuticals, Inc Inhibitors of fatty acid amide hydrolase
WO2010118155A1 (en) 2009-04-07 2010-10-14 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
WO2010118159A1 (en) 2009-04-07 2010-10-14 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US8709489B2 (en) 2009-09-30 2014-04-29 Surmodics, Inc. Emulsions containing arylboronic acids and medical articles made therefrom
BR112012019120A2 (pt) 2010-02-03 2016-06-28 Infinity Pharmaceuticais Inc forma sólida, composição farmacêutica, método de preparação do composto 1, método de tratamento de uma condição mediada por faah
US8546617B1 (en) 2012-03-23 2013-10-01 Empire Technology Development Llc Dioxaborinanes and uses thereof
WO2014021845A1 (en) * 2012-07-31 2014-02-06 Empire Technology Development Llc Polymerizable organoboron alkyd resin anti fouling coatings
WO2014062794A1 (en) * 2012-10-17 2014-04-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods for improving glucose uptake
CA2903281C (en) 2013-03-08 2022-11-29 The University Of British Columbia Substituted organofluoroborates as imaging agents
EP3913068B1 (en) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
CN106243343B (zh) * 2016-08-11 2018-04-03 江苏大学 一种苯硼酸功能化嵌段聚合物的合成及应用
CA3118223A1 (en) 2018-12-18 2020-06-25 Provincial Health Services Authority Dual mode 18f-labelled theranostic compounds and uses thereof
WO2022082312A1 (en) 2020-10-21 2022-04-28 Provincial Health Services Authority Novel cxcr4-targeting compounds
EP4313033A4 (en) * 2021-03-24 2025-04-23 Trustees Of Tufts College BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS

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Also Published As

Publication number Publication date
US20050107336A1 (en) 2005-05-19
WO2003002570A1 (en) 2003-01-09
CA2489681A1 (en) 2003-01-09
US6858592B2 (en) 2005-02-22
EP1404685A1 (en) 2004-04-07
DE60214713D1 (de) 2006-10-26
US20060128664A1 (en) 2006-06-15
DE60214713T2 (de) 2007-09-06
HK1065046A1 (en) 2005-02-08
US7049304B2 (en) 2006-05-23
CY1105829T1 (el) 2011-02-02
ATE339426T1 (de) 2006-10-15
ES2275888T3 (es) 2007-06-16
AU2005220192A1 (en) 2005-12-01
EP1404685B1 (en) 2006-09-13
US20030064963A1 (en) 2003-04-03
DK1404685T3 (da) 2007-01-22
JP2004535452A (ja) 2004-11-25
PT1404685E (pt) 2007-01-31
US7456156B2 (en) 2008-11-25

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