DE60129432T2 - Verfahren zur rückfaltung von proteinen mit freien cysteinresten - Google Patents
Verfahren zur rückfaltung von proteinen mit freien cysteinresten Download PDFInfo
- Publication number
- DE60129432T2 DE60129432T2 DE60129432T DE60129432T DE60129432T2 DE 60129432 T2 DE60129432 T2 DE 60129432T2 DE 60129432 T DE60129432 T DE 60129432T DE 60129432 T DE60129432 T DE 60129432T DE 60129432 T2 DE60129432 T2 DE 60129432T2
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- Prior art keywords
- cysteine
- csf
- protein
- proteins
- refolding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20461700P | 2000-05-16 | 2000-05-16 | |
| US204617P | 2000-05-16 | ||
| PCT/US2001/016088 WO2001087925A2 (en) | 2000-05-16 | 2001-05-16 | Methods for refolding proteins containing free cysteine residues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60129432D1 DE60129432D1 (de) | 2007-08-30 |
| DE60129432T2 true DE60129432T2 (de) | 2008-04-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60129432T Expired - Lifetime DE60129432T2 (de) | 2000-05-16 | 2001-05-16 | Verfahren zur rückfaltung von proteinen mit freien cysteinresten |
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| Country | Link |
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| US (3) | US7306931B2 (enExample) |
| EP (1) | EP1284987B1 (enExample) |
| JP (2) | JP4873818B2 (enExample) |
| CN (1) | CN1318443C (enExample) |
| AT (1) | ATE367398T1 (enExample) |
| AU (2) | AU2001274853B2 (enExample) |
| CA (1) | CA2408851C (enExample) |
| DE (1) | DE60129432T2 (enExample) |
| ES (1) | ES2290142T3 (enExample) |
| IL (2) | IL152804A0 (enExample) |
| NZ (1) | NZ522847A (enExample) |
| WO (1) | WO2001087925A2 (enExample) |
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-
2001
- 2001-05-16 NZ NZ522847A patent/NZ522847A/en not_active IP Right Cessation
- 2001-05-16 WO PCT/US2001/016088 patent/WO2001087925A2/en not_active Ceased
- 2001-05-16 DE DE60129432T patent/DE60129432T2/de not_active Expired - Lifetime
- 2001-05-16 CN CNB018128556A patent/CN1318443C/zh not_active Expired - Fee Related
- 2001-05-16 IL IL15280401A patent/IL152804A0/xx unknown
- 2001-05-16 CA CA2408851A patent/CA2408851C/en not_active Expired - Lifetime
- 2001-05-16 JP JP2001585144A patent/JP4873818B2/ja not_active Expired - Fee Related
- 2001-05-16 EP EP01941504A patent/EP1284987B1/en not_active Expired - Lifetime
- 2001-05-16 US US10/276,358 patent/US7306931B2/en not_active Expired - Lifetime
- 2001-05-16 AU AU2001274853A patent/AU2001274853B2/en not_active Ceased
- 2001-05-16 AT AT01941504T patent/ATE367398T1/de not_active IP Right Cessation
- 2001-05-16 ES ES01941504T patent/ES2290142T3/es not_active Expired - Lifetime
- 2001-05-16 AU AU7485301A patent/AU7485301A/xx active Pending
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2002
- 2002-11-12 IL IL152804A patent/IL152804A/en not_active IP Right Cessation
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2007
- 2007-12-11 US US12/001,639 patent/US20090269804A1/en not_active Abandoned
-
2010
- 2010-09-29 US US12/893,764 patent/US8932828B2/en not_active Expired - Fee Related
-
2011
- 2011-04-26 JP JP2011098711A patent/JP5517991B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60129432D1 (de) | 2007-08-30 |
| US7306931B2 (en) | 2007-12-11 |
| CA2408851A1 (en) | 2001-11-22 |
| AU2001274853C1 (en) | 2001-11-26 |
| EP1284987B1 (en) | 2007-07-18 |
| AU7485301A (en) | 2001-11-26 |
| IL152804A0 (en) | 2003-06-24 |
| HK1050014A1 (en) | 2003-06-06 |
| US20040018586A1 (en) | 2004-01-29 |
| JP2011173911A (ja) | 2011-09-08 |
| ES2290142T3 (es) | 2008-02-16 |
| EP1284987A2 (en) | 2003-02-26 |
| US20110189124A1 (en) | 2011-08-04 |
| ATE367398T1 (de) | 2007-08-15 |
| CN1318443C (zh) | 2007-05-30 |
| IL152804A (en) | 2010-11-30 |
| JP4873818B2 (ja) | 2012-02-08 |
| JP2004508014A (ja) | 2004-03-18 |
| US8932828B2 (en) | 2015-01-13 |
| JP5517991B2 (ja) | 2014-06-11 |
| AU2001274853B2 (en) | 2007-03-22 |
| WO2001087925A2 (en) | 2001-11-22 |
| NZ522847A (en) | 2004-11-26 |
| US20090269804A1 (en) | 2009-10-29 |
| CA2408851C (en) | 2011-07-12 |
| WO2001087925A3 (en) | 2002-08-01 |
| CN1443194A (zh) | 2003-09-17 |
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