DE60103976D1 - Pyrimidinylcarboxamiden als inhibitoren der pde4 isoenzyme - Google Patents

Pyrimidinylcarboxamiden als inhibitoren der pde4 isoenzyme

Info

Publication number
DE60103976D1
DE60103976D1 DE60103976T DE60103976T DE60103976D1 DE 60103976 D1 DE60103976 D1 DE 60103976D1 DE 60103976 T DE60103976 T DE 60103976T DE 60103976 T DE60103976 T DE 60103976T DE 60103976 D1 DE60103976 D1 DE 60103976D1
Authority
DE
Germany
Prior art keywords
carboxamides
pyrimidinyl
inhibitors
pde4 isoenzyme
isoenzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60103976T
Other languages
English (en)
Other versions
DE60103976T2 (de
Inventor
Robert James Chambers
Thomas Victor Magee
Anthony Marfat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of DE60103976D1 publication Critical patent/DE60103976D1/de
Publication of DE60103976T2 publication Critical patent/DE60103976T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
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DE60103976T 2000-01-31 2001-01-30 Pyrimidinylcarboxamiden als inhibitoren der pde4 isoenzyme Expired - Fee Related DE60103976T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17928200P 2000-01-31 2000-01-31
US179282P 2000-01-31
PCT/IB2001/000125 WO2001057025A1 (en) 2000-01-31 2001-01-30 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes

Publications (2)

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DE60103976D1 true DE60103976D1 (de) 2004-07-29
DE60103976T2 DE60103976T2 (de) 2005-07-21

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EP (1) EP1252157B1 (de)
JP (1) JP2003522165A (de)
KR (1) KR20020071029A (de)
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AP (1) AP2002002590A0 (de)
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ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
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