ATE293109T1 - Nikotinsäureamid-derivate und ihre mimetika als inhibitoren von pde4-isozyms - Google Patents

Nikotinsäureamid-derivate und ihre mimetika als inhibitoren von pde4-isozyms

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Publication number
ATE293109T1
ATE293109T1 AT02250202T AT02250202T ATE293109T1 AT E293109 T1 ATE293109 T1 AT E293109T1 AT 02250202 T AT02250202 T AT 02250202T AT 02250202 T AT02250202 T AT 02250202T AT E293109 T1 ATE293109 T1 AT E293109T1
Authority
AT
Austria
Prior art keywords
oxadiazol
substituted
triazol
chem
moiety
Prior art date
Application number
AT02250202T
Other languages
English (en)
Inventor
Robert J Chambers
Thomas V Magee
Anthony Marfat
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE293109T1 publication Critical patent/ATE293109T1/de

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
AT02250202T 2001-01-31 2002-01-11 Nikotinsäureamid-derivate und ihre mimetika als inhibitoren von pde4-isozyms ATE293109T1 (de)

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US26524001P 2001-01-31 2001-01-31

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ATE293109T1 true ATE293109T1 (de) 2005-04-15

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AT02250202T ATE293109T1 (de) 2001-01-31 2002-01-11 Nikotinsäureamid-derivate und ihre mimetika als inhibitoren von pde4-isozyms

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EP (1) EP1229034B1 (de)
JP (1) JP2002284766A (de)
AT (1) ATE293109T1 (de)
BR (1) BR0200250A (de)
CA (1) CA2369462A1 (de)
DE (1) DE60203652T2 (de)
ES (1) ES2239203T3 (de)
MX (1) MXPA02001141A (de)

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JP2011530525A (ja) 2008-08-05 2011-12-22 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション 新規なメチレンジオキシフェノール系化合物および疾患処置のためのそれらの使用
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ES2900342T3 (es) 2012-08-21 2022-03-16 Sanofi Biotechnology Métodos para tratar o prevenir el asma administrando un antagonista de IL-4R
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CN108273039B (zh) * 2015-12-16 2021-04-30 新乡医学院第一附属医院 一种治疗溶血性贫血的药物组合物及其应用
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EP1229034A1 (de) 2002-08-07
EP1229034B1 (de) 2005-04-13
MXPA02001141A (es) 2002-09-18
DE60203652D1 (de) 2005-05-19
CA2369462A1 (en) 2002-07-31
DE60203652T2 (de) 2005-09-08
ES2239203T3 (es) 2005-09-16
JP2002284766A (ja) 2002-10-03

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