DE60203652D1 - Nikotinsäureamid-Derivate und ihre Mimetika als Inhibitoren von PDE4-Isozyms - Google Patents

Nikotinsäureamid-Derivate und ihre Mimetika als Inhibitoren von PDE4-Isozyms

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Publication number
DE60203652D1
DE60203652D1 DE60203652T DE60203652T DE60203652D1 DE 60203652 D1 DE60203652 D1 DE 60203652D1 DE 60203652 T DE60203652 T DE 60203652T DE 60203652 T DE60203652 T DE 60203652T DE 60203652 D1 DE60203652 D1 DE 60203652D1
Authority
DE
Germany
Prior art keywords
oxadiazol
substituted
triazol
chem
moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60203652T
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English (en)
Other versions
DE60203652T2 (de
Inventor
Robert J Chambers
Thomas V Magee
Anthony Marfat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of DE60203652D1 publication Critical patent/DE60203652D1/de
Application granted granted Critical
Publication of DE60203652T2 publication Critical patent/DE60203652T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
DE60203652T 2001-01-31 2002-01-11 Nikotinsäureamid-Derivate und ihre Mimetika als Inhibitoren von PDE4-Isozyme Expired - Fee Related DE60203652T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26524001P 2001-01-31 2001-01-31
US265240P 2001-01-31

Publications (2)

Publication Number Publication Date
DE60203652D1 true DE60203652D1 (de) 2005-05-19
DE60203652T2 DE60203652T2 (de) 2005-09-08

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DE60203652T Expired - Fee Related DE60203652T2 (de) 2001-01-31 2002-01-11 Nikotinsäureamid-Derivate und ihre Mimetika als Inhibitoren von PDE4-Isozyme

Country Status (8)

Country Link
EP (1) EP1229034B1 (de)
JP (1) JP2002284766A (de)
AT (1) ATE293109T1 (de)
BR (1) BR0200250A (de)
CA (1) CA2369462A1 (de)
DE (1) DE60203652T2 (de)
ES (1) ES2239203T3 (de)
MX (1) MXPA02001141A (de)

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US20040001895A1 (en) * 2002-06-17 2004-01-01 Pfizer Inc. Combination treatment for depression and anxiety
JP2006508996A (ja) * 2002-11-27 2006-03-16 アルタナ　ファルマ　アクチエンゲゼルシャフト 悪液質の治療における使用のための、ｐｄｅ４及びｐｄｅ３／４インヒビター
AU2004236085B2 (en) * 2003-05-09 2010-03-25 Asahi Glass Company, Limited Processes for producing 3-substituted 2-chloro-5-fluoropyridine or salt thereof
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
KR100747401B1 (ko) * 2003-09-03 2007-08-08 화이자 인코포레이티드 프로스타글란딘 ｅ2 길항제로서의 페닐 또는 피리딜 아미드 화합물
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
US20050142104A1 (en) * 2003-11-06 2005-06-30 Zeldis Jerome B. Methods of using and compositions comprising PDE4 modulators for the treatment and management of asbestos-related diseases and disorders
AU2005238291A1 (en) 2004-05-04 2005-11-10 Pfizer Inc. Substituted methyl aryl or heteroaryl amide compounds
PE20060272A1 (es) 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
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ME02736B (de) 2005-12-21 2017-10-20 Janssen Pharmaceutica Nv Triazolpyridazine als tyrosinkinasehemmer
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ES2239203T3 (es) 2005-09-16
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BR0200250A (pt) 2002-10-08
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