DE60037277T2 - Adenosinrezeptor-agonist oder antagonist enthaltende pharmazeutische zusammensetzungen - Google Patents

Adenosinrezeptor-agonist oder antagonist enthaltende pharmazeutische zusammensetzungen Download PDF

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Publication number
DE60037277T2
DE60037277T2 DE60037277T DE60037277T DE60037277T2 DE 60037277 T2 DE60037277 T2 DE 60037277T2 DE 60037277 T DE60037277 T DE 60037277T DE 60037277 T DE60037277 T DE 60037277T DE 60037277 T2 DE60037277 T2 DE 60037277T2
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group
use according
active ingredient
alkyl
pharmaceutical composition
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Expired - Lifetime
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DE60037277T
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German (de)
English (en)
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DE60037277D1 (de
Inventor
Pnina Fishman
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Can Fite Biopharma Ltd
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Can Fite Biopharma Ltd
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Priority claimed from IL13186499A external-priority patent/IL131864A0/xx
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Publication of DE60037277D1 publication Critical patent/DE60037277D1/de
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Publication of DE60037277T2 publication Critical patent/DE60037277T2/de
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Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60037277T 1999-09-10 2000-09-08 Adenosinrezeptor-agonist oder antagonist enthaltende pharmazeutische zusammensetzungen Expired - Lifetime DE60037277T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IL13186499A IL131864A0 (en) 1999-09-10 1999-09-10 Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist
IL13186499 1999-09-10
IL13368099 1999-12-23
IL13368099A IL133680A0 (en) 1999-09-10 1999-12-23 Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist
PCT/IL2000/000550 WO2001019360A2 (en) 1999-09-10 2000-09-08 Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist

Publications (2)

Publication Number Publication Date
DE60037277D1 DE60037277D1 (de) 2008-01-10
DE60037277T2 true DE60037277T2 (de) 2008-10-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037277T Expired - Lifetime DE60037277T2 (de) 1999-09-10 2000-09-08 Adenosinrezeptor-agonist oder antagonist enthaltende pharmazeutische zusammensetzungen

Country Status (19)

Country Link
US (2) US7064112B1 (enExample)
EP (1) EP1261322B1 (enExample)
JP (2) JP4980530B2 (enExample)
KR (2) KR100584797B1 (enExample)
CN (1) CN100358512C (enExample)
AU (1) AU782826B2 (enExample)
BR (1) BR0013905A (enExample)
CA (1) CA2384111C (enExample)
DE (1) DE60037277T2 (enExample)
DK (1) DK1261322T3 (enExample)
ES (1) ES2296637T3 (enExample)
HK (1) HK1052653B (enExample)
HU (1) HU226913B1 (enExample)
IL (1) IL133680A0 (enExample)
MX (1) MXPA02002546A (enExample)
PL (1) PL199852B1 (enExample)
PT (1) PT1261322E (enExample)
RU (1) RU2239455C2 (enExample)
WO (1) WO2001019360A2 (enExample)

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Also Published As

Publication number Publication date
KR20020038749A (ko) 2002-05-23
CA2384111A1 (en) 2001-03-22
HU226913B1 (en) 2010-03-01
KR20060036490A (ko) 2006-04-28
CA2384111C (en) 2008-05-27
CN100358512C (zh) 2008-01-02
AU6863400A (en) 2001-04-17
BR0013905A (pt) 2003-07-15
IL133680A0 (en) 2001-04-30
RU2239455C2 (ru) 2004-11-10
PL356469A1 (en) 2004-06-28
DK1261322T3 (da) 2008-04-07
EP1261322A2 (en) 2002-12-04
JP2007204496A (ja) 2007-08-16
WO2001019360A2 (en) 2001-03-22
JP2003514771A (ja) 2003-04-22
US7064112B1 (en) 2006-06-20
WO2001019360A3 (en) 2002-09-19
HUP0203870A2 (hu) 2003-03-28
HUP0203870A3 (en) 2005-07-28
KR100674529B1 (ko) 2007-01-30
HK1052653A1 (zh) 2003-09-26
KR100584797B1 (ko) 2006-06-02
MXPA02002546A (es) 2003-07-21
RU2002109228A (ru) 2004-01-10
PT1261322E (pt) 2008-01-09
ES2296637T3 (es) 2008-05-01
AU782826B2 (en) 2005-09-01
DE60037277D1 (de) 2008-01-10
HK1052653B (zh) 2008-08-01
CN1391468A (zh) 2003-01-15
JP4980530B2 (ja) 2012-07-18
PL199852B1 (pl) 2008-11-28
US20060084626A1 (en) 2006-04-20
EP1261322B1 (en) 2007-11-28

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