DE60034713D1 - Chinolyl-propyl-piperidinderivate und deren Verwendung als antimikrobielle Wirkstoffe - Google Patents

Chinolyl-propyl-piperidinderivate und deren Verwendung als antimikrobielle Wirkstoffe

Info

Publication number
DE60034713D1
DE60034713D1 DE60034713T DE60034713T DE60034713D1 DE 60034713 D1 DE60034713 D1 DE 60034713D1 DE 60034713 T DE60034713 T DE 60034713T DE 60034713 T DE60034713 T DE 60034713T DE 60034713 D1 DE60034713 D1 DE 60034713D1
Authority
DE
Germany
Prior art keywords
quinolyl
propyl
antimicrobial agents
piperidine derivatives
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60034713T
Other languages
English (en)
Other versions
DE60034713T2 (de
Inventor
Jean-Christophe Carry
Michel Cheve
Ahmad Youssef El
Michel Evers
Jean-Luc Malleron
Serge Mignani
Michel Tabart
Fabrice Viviani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of DE60034713D1 publication Critical patent/DE60034713D1/de
Publication of DE60034713T2 publication Critical patent/DE60034713T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
DE60034713T 1999-09-17 2000-09-14 Derivate des Chinolylpropylpiperidins, ihre Herstellung sowie Zusammensetzungen, in denen sie enthalten sind Expired - Fee Related DE60034713T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9911679 1999-09-17
FR9911679A FR2798656B1 (fr) 1999-09-17 1999-09-17 Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
DE60034713D1 true DE60034713D1 (de) 2007-06-14
DE60034713T2 DE60034713T2 (de) 2008-01-17

Family

ID=9549990

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60034713T Expired - Fee Related DE60034713T2 (de) 1999-09-17 2000-09-14 Derivate des Chinolylpropylpiperidins, ihre Herstellung sowie Zusammensetzungen, in denen sie enthalten sind
DE60016611T Expired - Fee Related DE60016611T2 (de) 1999-09-17 2000-09-14 Chinolinpropyl-piperidinderivate und deren verwendung als antibakterielle wirkstoffe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60016611T Expired - Fee Related DE60016611T2 (de) 1999-09-17 2000-09-14 Chinolinpropyl-piperidinderivate und deren verwendung als antibakterielle wirkstoffe

Country Status (30)

Country Link
EP (2) EP1484328B1 (de)
JP (1) JP2004527448A (de)
KR (1) KR20020038757A (de)
CN (1) CN1374959A (de)
AP (1) AP2002002459A0 (de)
AT (1) ATE284399T1 (de)
AU (1) AU7429500A (de)
BG (1) BG106524A (de)
BR (1) BR0014060A (de)
CA (1) CA2383836A1 (de)
CZ (1) CZ2002940A3 (de)
DE (2) DE60034713T2 (de)
DZ (1) DZ3195A1 (de)
EA (1) EA005183B1 (de)
EE (1) EE200200138A (de)
FR (1) FR2798656B1 (de)
GE (1) GEP20043223B (de)
HR (1) HRP20020214A2 (de)
HU (1) HUP0204283A3 (de)
IL (1) IL148720A0 (de)
MA (1) MA26820A1 (de)
MX (1) MXPA02001979A (de)
NO (1) NO20021253L (de)
OA (1) OA12022A (de)
PL (1) PL354809A1 (de)
SK (1) SK3632002A3 (de)
TN (1) TNSN00184A1 (de)
WO (1) WO2001025227A2 (de)
YU (1) YU19002A (de)
ZA (1) ZA200202073B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
DE60125373T2 (de) 2000-07-26 2007-10-18 Smithkline Beecham P.L.C., Brentford Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
WO2003064431A2 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
EP2181996A1 (de) 2002-01-29 2010-05-05 Glaxo Group Limited Aminopiperidinderivate
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
FR2842807A1 (fr) * 2002-07-23 2004-01-30 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, procede et intermediaires de preparation et compositions les renfermant
FR2844270B1 (fr) 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
CA2500320A1 (en) * 2002-10-10 2004-04-29 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Novel compounds with antibacterial activity
JP4704755B2 (ja) 2002-11-05 2011-06-22 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
DE60334016D1 (de) 2002-11-05 2010-10-14 Glaxo Group Ltd Antibakterielle mittel
EP1567520B1 (de) 2002-12-04 2008-10-15 Glaxo Group Limited Chinoline und stickstoffhaltige derivatedavon und deren verwendung als antibakterielle mittel
EP1799674B1 (de) * 2004-10-05 2010-05-05 Actelion Pharmaceuticals Ltd. Neue piperidin-antibiotika
CN101039935B (zh) * 2004-10-05 2011-04-20 埃科特莱茵药品有限公司 哌啶抗生素
JP2008528587A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
EP1846418A4 (de) 2005-01-25 2009-12-23 Glaxo Group Ltd Antibakterielle wirkstoffe
WO2006081178A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
US7605169B2 (en) 2005-01-25 2009-10-20 Glaxo Group Limited Antibacterial agents
CA2635126A1 (en) 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
WO2007115947A1 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (de) 2007-05-18 2008-11-19 Glaxo Group Limited Derivate und Analoge von N-Ethylquinolonen und N-Ethylazaquinolonen
WO2008139288A2 (en) * 2007-05-09 2008-11-20 Pfizer Inc. Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials
EP2080761A1 (de) 2008-01-18 2009-07-22 Glaxo Group Limited Verbindungen
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
EP2379554B1 (de) 2009-01-15 2015-11-11 Glaxo Group Limited Als antibakterielle mittel geeignete naphthyridin-2-(1h)-onverbindungen
CN105636945B (zh) * 2013-10-14 2017-11-17 卫材R&D管理有限公司 选择性取代的喹啉化合物
EA031589B1 (ru) 2014-08-22 2019-01-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
KR20180094939A (ko) 2015-12-17 2018-08-24 메르크 파텐트 게엠베하 폴리시클릭 tlr7/8 안타고니스트 및 면역 질환의 치료에서 이들의 용도
SG11201900947RA (en) 2016-08-08 2019-02-27 Merck Patent Gmbh Tlr7/8 antagonists and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2201674T3 (es) * 1998-01-26 2004-03-16 Smithkline Beecham Plc Derivados de quinolina con propiedades antibacterianas.
AU2437900A (en) * 1999-01-20 2000-08-07 Smithkline Beecham Plc Piperidinylquinolines as protein tyrosine kinase inhibitors

Also Published As

Publication number Publication date
EP1484328A1 (de) 2004-12-08
PL354809A1 (en) 2004-02-23
TNSN00184A1 (fr) 2005-11-10
EA005183B1 (ru) 2004-12-30
CN1374959A (zh) 2002-10-16
NO20021253D0 (no) 2002-03-13
EP1218370B1 (de) 2004-12-08
BG106524A (en) 2003-01-31
WO2001025227A2 (fr) 2001-04-12
EA200200374A1 (ru) 2002-10-31
MXPA02001979A (es) 2002-08-20
MA26820A1 (fr) 2004-12-20
YU19002A (sh) 2005-06-10
DE60016611D1 (de) 2005-01-13
AU7429500A (en) 2001-05-10
ATE284399T1 (de) 2004-12-15
IL148720A0 (en) 2002-09-12
NO20021253L (no) 2002-04-24
BR0014060A (pt) 2002-05-21
SK3632002A3 (en) 2003-04-01
HRP20020214A2 (en) 2005-04-30
GEP20043223B (en) 2004-04-26
OA12022A (fr) 2006-04-19
DE60034713T2 (de) 2008-01-17
FR2798656B1 (fr) 2004-12-17
WO2001025227A3 (fr) 2001-11-22
AP2002002459A0 (en) 2002-06-30
KR20020038757A (ko) 2002-05-23
EP1218370A2 (de) 2002-07-03
HUP0204283A3 (en) 2004-07-28
EP1484328B1 (de) 2007-05-02
ZA200202073B (en) 2003-08-27
EE200200138A (et) 2003-06-16
JP2004527448A (ja) 2004-09-09
CA2383836A1 (fr) 2001-04-12
CZ2002940A3 (cs) 2002-07-17
DZ3195A1 (fr) 2001-04-12
DE60016611T2 (de) 2005-12-22
HUP0204283A2 (hu) 2003-04-28
FR2798656A1 (fr) 2001-03-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee