BR0014060A - Derivado de quinolil propil piperidina, processo para preparação do mesmo, e, composição farmacêutica - Google Patents

Derivado de quinolil propil piperidina, processo para preparação do mesmo, e, composição farmacêutica

Info

Publication number
BR0014060A
BR0014060A BR0014060-0A BR0014060A BR0014060A BR 0014060 A BR0014060 A BR 0014060A BR 0014060 A BR0014060 A BR 0014060A BR 0014060 A BR0014060 A BR 0014060A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
preparing
piperidine derivative
propyl piperidine
quinolyl propyl
Prior art date
Application number
BR0014060-0A
Other languages
English (en)
Inventor
Jean-Luc Malleron
Michel Tabart
Jean-Christophe Carry
Michel Evers
Youssef El Ahmad
Serge Mignani
Fabrice Viviani
Michel Cheve
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BR0014060A publication Critical patent/BR0014060A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

"DERIVADO DE QUINOLIL PROPIL PIPERIDINA, PROCESSO PARA PREPARAçãO DO MESMO, E, COMPOSIçãO FARMACêUTICA". Um derivado de quinolil propil piperidina de fórmula geral (1) em que R~ 1~ é um átomo de hidrogênio ou halogênio, ou um radical hidróxi, R'~ 1~, é um átomo de hidrogênio, ou pode representar halogênio quando R~ 1~ é igualmente um átomo de halogênio, e R^ o^ é um átomo de hidrogênio. Estes derivados são agentes antimicrobianos.
BR0014060-0A 1999-09-17 2000-09-14 Derivado de quinolil propil piperidina, processo para preparação do mesmo, e, composição farmacêutica BR0014060A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9911679A FR2798656B1 (fr) 1999-09-17 1999-09-17 Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
PCT/FR2000/002541 WO2001025227A2 (fr) 1999-09-17 2000-09-14 Derives de la quinolyl propyl piperidine et leur utilisation en tant que antibacteriens

Publications (1)

Publication Number Publication Date
BR0014060A true BR0014060A (pt) 2002-05-21

Family

ID=9549990

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014060-0A BR0014060A (pt) 1999-09-17 2000-09-14 Derivado de quinolil propil piperidina, processo para preparação do mesmo, e, composição farmacêutica

Country Status (30)

Country Link
EP (2) EP1484328B1 (pt)
JP (1) JP2004527448A (pt)
KR (1) KR20020038757A (pt)
CN (1) CN1374959A (pt)
AP (1) AP2002002459A0 (pt)
AT (1) ATE284399T1 (pt)
AU (1) AU7429500A (pt)
BG (1) BG106524A (pt)
BR (1) BR0014060A (pt)
CA (1) CA2383836A1 (pt)
CZ (1) CZ2002940A3 (pt)
DE (2) DE60034713T2 (pt)
DZ (1) DZ3195A1 (pt)
EA (1) EA005183B1 (pt)
EE (1) EE200200138A (pt)
FR (1) FR2798656B1 (pt)
GE (1) GEP20043223B (pt)
HR (1) HRP20020214A2 (pt)
HU (1) HUP0204283A3 (pt)
IL (1) IL148720A0 (pt)
MA (1) MA26820A1 (pt)
MX (1) MXPA02001979A (pt)
NO (1) NO20021253L (pt)
OA (1) OA12022A (pt)
PL (1) PL354809A1 (pt)
SK (1) SK3632002A3 (pt)
TN (1) TNSN00184A1 (pt)
WO (1) WO2001025227A2 (pt)
YU (1) YU19002A (pt)
ZA (1) ZA200202073B (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
DE60125373T2 (de) 2000-07-26 2007-10-18 Smithkline Beecham P.L.C., Brentford Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
WO2003064431A2 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
EP2181996A1 (en) 2002-01-29 2010-05-05 Glaxo Group Limited Aminopiperidine derivatives
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
FR2842807A1 (fr) * 2002-07-23 2004-01-30 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, procede et intermediaires de preparation et compositions les renfermant
FR2844270B1 (fr) 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
CA2500320A1 (en) * 2002-10-10 2004-04-29 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Novel compounds with antibacterial activity
JP4704755B2 (ja) 2002-11-05 2011-06-22 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
DE60334016D1 (de) 2002-11-05 2010-10-14 Glaxo Group Ltd Antibakterielle mittel
EP1567520B1 (en) 2002-12-04 2008-10-15 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
EP1799674B1 (en) * 2004-10-05 2010-05-05 Actelion Pharmaceuticals Ltd. New piperidine antibiotics
CN101039935B (zh) * 2004-10-05 2011-04-20 埃科特莱茵药品有限公司 哌啶抗生素
JP2008528587A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
EP1846418A4 (en) 2005-01-25 2009-12-23 Glaxo Group Ltd ANTIBACTERIAL ACTIVE SUBSTANCES
WO2006081178A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
US7605169B2 (en) 2005-01-25 2009-10-20 Glaxo Group Limited Antibacterial agents
CA2635126A1 (en) 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
WO2007115947A1 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
WO2008139288A2 (en) * 2007-05-09 2008-11-20 Pfizer Inc. Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
EP2379554B1 (en) 2009-01-15 2015-11-11 Glaxo Group Limited Naphthyridin-2(1h)-one compounds useful as antibacterials
CN105636945B (zh) * 2013-10-14 2017-11-17 卫材R&D管理有限公司 选择性取代的喹啉化合物
EA031589B1 (ru) 2014-08-22 2019-01-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
KR20180094939A (ko) 2015-12-17 2018-08-24 메르크 파텐트 게엠베하 폴리시클릭 tlr7/8 안타고니스트 및 면역 질환의 치료에서 이들의 용도
SG11201900947RA (en) 2016-08-08 2019-02-27 Merck Patent Gmbh Tlr7/8 antagonists and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2201674T3 (es) * 1998-01-26 2004-03-16 Smithkline Beecham Plc Derivados de quinolina con propiedades antibacterianas.
AU2437900A (en) * 1999-01-20 2000-08-07 Smithkline Beecham Plc Piperidinylquinolines as protein tyrosine kinase inhibitors

Also Published As

Publication number Publication date
EP1484328A1 (fr) 2004-12-08
PL354809A1 (en) 2004-02-23
TNSN00184A1 (fr) 2005-11-10
EA005183B1 (ru) 2004-12-30
CN1374959A (zh) 2002-10-16
NO20021253D0 (no) 2002-03-13
EP1218370B1 (fr) 2004-12-08
BG106524A (en) 2003-01-31
WO2001025227A2 (fr) 2001-04-12
EA200200374A1 (ru) 2002-10-31
MXPA02001979A (es) 2002-08-20
MA26820A1 (fr) 2004-12-20
YU19002A (sh) 2005-06-10
DE60016611D1 (de) 2005-01-13
AU7429500A (en) 2001-05-10
ATE284399T1 (de) 2004-12-15
IL148720A0 (en) 2002-09-12
NO20021253L (no) 2002-04-24
SK3632002A3 (en) 2003-04-01
HRP20020214A2 (en) 2005-04-30
GEP20043223B (en) 2004-04-26
OA12022A (fr) 2006-04-19
DE60034713T2 (de) 2008-01-17
FR2798656B1 (fr) 2004-12-17
WO2001025227A3 (fr) 2001-11-22
AP2002002459A0 (en) 2002-06-30
KR20020038757A (ko) 2002-05-23
EP1218370A2 (fr) 2002-07-03
HUP0204283A3 (en) 2004-07-28
EP1484328B1 (fr) 2007-05-02
ZA200202073B (en) 2003-08-27
EE200200138A (et) 2003-06-16
JP2004527448A (ja) 2004-09-09
CA2383836A1 (fr) 2001-04-12
CZ2002940A3 (cs) 2002-07-17
DZ3195A1 (fr) 2001-04-12
DE60034713D1 (de) 2007-06-14
DE60016611T2 (de) 2005-12-22
HUP0204283A2 (hu) 2003-04-28
FR2798656A1 (fr) 2001-03-23

Similar Documents

Publication Publication Date Title
BR0014060A (pt) Derivado de quinolil propil piperidina, processo para preparação do mesmo, e, composição farmacêutica
BR0012880A (pt) Derivados de mutilina e seu uso como antibacterianos
BR9913592A (pt) Compostos, processo de preparação dos compostos, e, composições farmacêuticas
NO20074657L (no) Nitrogenholdige aromatiske ringforbindelser
BR0007500A (pt) Composto triazol, fármaco, e, uso do composto
DE60032780D1 (de) Tetrahydroquinolin-derivate
BR0210028A (pt) Agentes antibacterianos
EE200100558A (et) Triarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi raviotstarbeline kasutamine
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
BR0215312A (pt) Uso de um composto, método para inibir a aurora quinase em um animal de sangue quente, composto, composição farmacêutica, e, processo para a preparação de um composto
BR0208678A (pt) Composto, composição farmacêutica, uso de um composto
BR0213242A (pt) Composto ou um seu sal ou solvato, composto e seus sais de adição de ácido fisiologicamente aceitáveis, composição farmacêutica, método de tratamento de um ou mais distúrbios, uso de um composto, e, processo de preparação de um composto
BR9813390A (pt) Composto, processo para a preparação do mesmo, e uso do mesmo, composição farmacêutica, processo para a preparação da mesma, e, processo para efetuar a imunossupressão
ID27178A (id) Senyawa aminosikloheksil eter dan penggunaannya
GT200000103A (es) Trifluorbutenos nematocidas.
BR0211440A (pt) Derivados de 2h-piridazina-3-ona, composições farmacêuticas contendo o mesmo e processo para a preparação do ingrediente ativo
BR0316609A (pt) Sinomenina e compostos de sinomenina, sìntese e uso
GEP20032913B (en) Thienylazolylalcoxyethanamines, Their Preparation and Their Application as Medicaments
BR0007589A (pt) Inibidores da proliferação de células
BR0113389A (pt) Compostos que inibem a atividade do fator xa
BR0215027A (pt) Derivados de 6-aminomorfinano, processo de preparação para o mesmo e sua aplicação
BR0311410A (pt) Composto de piperidina
WO2001010860A3 (en) Quinazolinone and azaquinazolinone derivatives
BR9911250A (pt) Processo para preparação de compostos
BR0209604A (pt) Derivados de 1-oxa-3,9-diaza-spiro-5,5-undecan-2-onas e seu uso como antagonista do receptor para neuricinina

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.