DE60028401T2 - Vorrichtung zur wiederherstellung einer therapeutischen suspension oder dispersion - Google Patents
Vorrichtung zur wiederherstellung einer therapeutischen suspension oder dispersion Download PDFInfo
- Publication number
- DE60028401T2 DE60028401T2 DE60028401T DE60028401T DE60028401T2 DE 60028401 T2 DE60028401 T2 DE 60028401T2 DE 60028401 T DE60028401 T DE 60028401T DE 60028401 T DE60028401 T DE 60028401T DE 60028401 T2 DE60028401 T2 DE 60028401T2
- Authority
- DE
- Germany
- Prior art keywords
- container
- piston
- carpule
- proximal
- injection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000725 suspension Substances 0.000 title claims description 8
- 239000006185 dispersion Substances 0.000 title claims description 5
- 230000001225 therapeutic effect Effects 0.000 title description 4
- 239000007924 injection Substances 0.000 claims description 79
- 238000002347 injection Methods 0.000 claims description 79
- 239000007788 liquid Substances 0.000 claims description 58
- 238000000034 method Methods 0.000 claims description 42
- 230000007246 mechanism Effects 0.000 claims description 41
- 239000000203 mixture Substances 0.000 claims description 37
- 239000000243 solution Substances 0.000 claims description 34
- 238000004806 packaging method and process Methods 0.000 claims description 28
- 238000002360 preparation method Methods 0.000 claims description 25
- 230000005540 biological transmission Effects 0.000 claims description 23
- 238000004108 freeze drying Methods 0.000 claims description 23
- 230000000903 blocking effect Effects 0.000 claims description 20
- 238000012546 transfer Methods 0.000 claims description 20
- 239000000945 filler Substances 0.000 claims description 18
- 230000033001 locomotion Effects 0.000 claims description 15
- 238000013459 approach Methods 0.000 claims description 8
- 230000009849 deactivation Effects 0.000 claims description 2
- 238000009472 formulation Methods 0.000 description 26
- 239000007787 solid Substances 0.000 description 16
- 238000011049 filling Methods 0.000 description 15
- 239000012528 membrane Substances 0.000 description 12
- 210000003811 finger Anatomy 0.000 description 10
- 230000006870 function Effects 0.000 description 8
- 239000011521 glass Substances 0.000 description 8
- 238000004659 sterilization and disinfection Methods 0.000 description 8
- 230000004913 activation Effects 0.000 description 7
- 239000002775 capsule Substances 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 238000007872 degassing Methods 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 239000002609 medium Substances 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 238000000926 separation method Methods 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 5
- 239000002184 metal Substances 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 238000005429 filling process Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 238000012858 packaging process Methods 0.000 description 3
- 230000035515 penetration Effects 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 239000012730 sustained-release form Substances 0.000 description 3
- 210000003813 thumb Anatomy 0.000 description 3
- 239000012736 aqueous medium Substances 0.000 description 2
- 238000004500 asepsis Methods 0.000 description 2
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 238000005553 drilling Methods 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000004005 microsphere Substances 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 238000009516 primary packaging Methods 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000011272 standard treatment Methods 0.000 description 2
- 238000013268 sustained release Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 244000089486 Phragmites australis subsp australis Species 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000002981 blocking agent Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 239000007972 injectable composition Substances 0.000 description 1
- 229940102213 injectable suspension Drugs 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000012792 lyophilization process Methods 0.000 description 1
- 239000008155 medical solution Substances 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000007420 reactivation Effects 0.000 description 1
- 238000003168 reconstitution method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000009517 secondary packaging Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
- A61M2005/2451—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing preventing delivery before mixing is completed, e.g. by locking mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
- A61M2005/247—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
- A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9912748 | 1999-10-13 | ||
| FR9912748A FR2799654B1 (fr) | 1999-10-13 | 1999-10-13 | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif |
| PCT/FR2000/002804 WO2001026718A1 (fr) | 1999-10-13 | 2000-10-10 | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60028401D1 DE60028401D1 (de) | 2006-07-06 |
| DE60028401T2 true DE60028401T2 (de) | 2007-05-24 |
Family
ID=9550868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60028401T Expired - Lifetime DE60028401T2 (de) | 1999-10-13 | 2000-10-10 | Vorrichtung zur wiederherstellung einer therapeutischen suspension oder dispersion |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6902543B1 (https=) |
| EP (1) | EP1223999B1 (https=) |
| JP (1) | JP4394325B2 (https=) |
| KR (1) | KR100848722B1 (https=) |
| CN (1) | CN1216657C (https=) |
| AR (1) | AR025958A1 (https=) |
| AT (1) | ATE327789T1 (https=) |
| AU (1) | AU7796400A (https=) |
| CA (1) | CA2386160C (https=) |
| CZ (1) | CZ302559B6 (https=) |
| DE (1) | DE60028401T2 (https=) |
| ES (1) | ES2261244T3 (https=) |
| FR (1) | FR2799654B1 (https=) |
| HU (1) | HU226437B1 (https=) |
| IL (2) | IL148897A0 (https=) |
| NZ (1) | NZ518286A (https=) |
| PL (1) | PL203757B1 (https=) |
| RU (1) | RU2258537C2 (https=) |
| WO (1) | WO2001026718A1 (https=) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6809804B1 (en) | 2000-05-11 | 2004-10-26 | Becton, Dickinson And Company | System and method for providing improved event reading and data processing capabilities in a flow cytometer |
| DE10129452A1 (de) * | 2001-06-19 | 2003-01-09 | Bosch Gmbh Robert | Verfahren zum Befüllen von im wesentlichen zylinderförmigen Ampullen |
| JP4112851B2 (ja) * | 2001-11-27 | 2008-07-02 | テルモ株式会社 | 2室型プレフィルドシリンジ |
| GB0217285D0 (en) | 2002-07-25 | 2002-09-04 | Cambridge Consultants | Syringes |
| NL1021236C2 (nl) * | 2002-08-08 | 2004-02-10 | Medical Patents Ltd | Injectiespuitsamenstel. |
| JP4144027B2 (ja) * | 2002-09-11 | 2008-09-03 | ニプロ株式会社 | 2成分混合タイプのプレフィルドシリンジ |
| FR2847887A1 (fr) * | 2002-12-02 | 2004-06-04 | Valois Sas | Reservoir de produits fluides |
| EP1685865A4 (en) * | 2003-11-21 | 2009-12-30 | Zhongshan Botai Pharmaceutic I | SYRINGE FOR PREMIXING DRUGS IN POWDER |
| FR2863161B1 (fr) | 2003-12-05 | 2006-09-01 | Map France | Capuchon pour conditionnement de securite pour flacon a usage medical |
| GB2414775B (en) | 2004-05-28 | 2008-05-21 | Cilag Ag Int | Releasable coupling and injection device |
| GB2414400B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414402B (en) | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
| AT500930B1 (de) * | 2004-10-25 | 2007-03-15 | Pharma Consult Ges M B H & Co | Verfahren und vorrichtung zum lyophilisieren, rekonstituieren und verabreichen eines rekonstituierten wirkstoffes |
| JP5165381B2 (ja) * | 2004-12-24 | 2013-03-21 | コリン パテント ホールディングス ピーティーワイ リミテッド | 安全注射器 |
| US7959600B2 (en) * | 2004-12-30 | 2011-06-14 | Byeong S. Chang | Container closure delivery system |
| US20060157507A1 (en) * | 2004-12-30 | 2006-07-20 | Chang Byeong S | Multi-functional container closure delivery system |
| US20060144869A1 (en) * | 2004-12-30 | 2006-07-06 | Chang Byeong S | Container closure delivery system |
| GB2425062B (en) | 2005-04-06 | 2010-07-21 | Cilag Ag Int | Injection device |
| GB2424836B (en) | 2005-04-06 | 2010-09-22 | Cilag Ag Int | Injection device (bayonet cap removal) |
| ITVI20050152A1 (it) * | 2005-05-20 | 2006-11-21 | Tecres Spa | Cartuccia per la conservazione e l'erogazione sterile di un composto bifasico, particolarmente per una resina acrilica |
| DE502005005547D1 (de) * | 2005-07-15 | 2008-11-13 | Dentaco Gmbh | Pipettiervorrichtung |
| DE602005018480D1 (de) | 2005-08-30 | 2010-02-04 | Cilag Gmbh Int | Nadelvorrichtung für eine vorgefüllte Spritze |
| US20110098656A1 (en) | 2005-09-27 | 2011-04-28 | Burnell Rosie L | Auto-injection device with needle protecting cap having outer and inner sleeves |
| US20080171971A1 (en) * | 2005-11-16 | 2008-07-17 | Diperna Paul Mario | Novel enhanced device and technique for mixing and dispensing a preserved agent |
| US7695449B2 (en) * | 2005-12-05 | 2010-04-13 | Xinming Wang | Automatic syringe |
| EP1998828A2 (en) * | 2006-03-17 | 2008-12-10 | Novo Nordisk A/S | A connectable device and a device assembly for delivering a liquid drug |
| CA2652206C (en) | 2006-05-25 | 2014-02-11 | Bayer Healthcare Llc | Reconstitution device |
| GB2438591B (en) | 2006-06-01 | 2011-07-13 | Cilag Gmbh Int | Injection device |
| GB2438593B (en) | 2006-06-01 | 2011-03-30 | Cilag Gmbh Int | Injection device (cap removal feature) |
| GB2438590B (en) | 2006-06-01 | 2011-02-09 | Cilag Gmbh Int | Injection device |
| EP2034945A1 (en) | 2006-06-21 | 2009-03-18 | Novo Nordisk A/S | A one-hand operated drug mixing and expelling device |
| JP5140668B2 (ja) | 2006-08-09 | 2013-02-06 | メッドミックス システムズ アーゲー | ピストン付き注入器 |
| WO2008151431A1 (en) * | 2007-06-13 | 2008-12-18 | Duoject Medical Systems Inc. | Device for transferring fluids from a cartridge to a container |
| KR101439466B1 (ko) * | 2007-11-08 | 2014-09-15 | 주식회사 엘지생명과학 | 약물 주사 장치 및 약물 주사용 키트 |
| AU2014280969B2 (en) * | 2008-05-14 | 2015-02-26 | Biolyph, Llc | Reagent preparation and dispensing device and methods for the same |
| US8940539B2 (en) * | 2008-05-14 | 2015-01-27 | Biolyph, L.L.C. | Reagent preparation and dispensing device and methods for the same |
| GB2461086B (en) | 2008-06-19 | 2012-12-05 | Cilag Gmbh Int | Injection device |
| DE102008030268B3 (de) * | 2008-06-19 | 2010-02-04 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Verfahren zum Befüllen von Doppelkammersystemen in vorsterilisierbaren Trägersystemen und vorsterilisierbares Trägersystem |
| GB2461085B (en) | 2008-06-19 | 2012-08-29 | Cilag Gmbh Int | Injection device |
| DE102008030267B3 (de) * | 2008-06-19 | 2010-01-28 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Verfahren zum Befüllen von Doppelkammersystemen in vorsterilisierbaren Trägersystemen und vorsterilisierbares Trägersystem |
| US8323262B2 (en) * | 2008-07-08 | 2012-12-04 | Hyperbranch Medical Technology, Inc. | Self-contained medical applicators for multiple component formulations, and methods of use thereof |
| CA2649160A1 (en) * | 2009-01-09 | 2010-07-09 | Duoject Medical Systems Inc. | Fluid transfer device |
| EP2403565B1 (en) * | 2009-02-26 | 2014-01-01 | G-Sense Ltd. | Pressurized reservoir system for storing and dispensing liquids |
| DE102009013211B4 (de) | 2009-03-17 | 2012-04-19 | Aap Biomaterials Gmbh | Vakuum-Mischvorrichtung für Knochenzement sowie Verfahren zum Mischen von Knochenzement |
| US20120191066A1 (en) * | 2009-06-25 | 2012-07-26 | Sanofi-Aventis Deutschland Gmbh | Prefilled Cannula Assembly |
| EP2737952B1 (en) * | 2009-08-10 | 2016-01-13 | West Pharmaceutical Services, Inc. | Method for filling flangeless containers |
| CN102844065B (zh) * | 2010-02-05 | 2015-10-14 | 赛诺菲-安万特德国有限公司 | 带可锁止的针护罩的载药模块 |
| CN102821802B (zh) * | 2010-02-05 | 2015-04-01 | 赛诺菲-安万特德国有限公司 | 具有双重针护罩的载药模块 |
| CA2803375C (en) | 2010-06-29 | 2016-05-10 | Biolyph, Llc | Reagent preparation assembly |
| CA2817038C (en) | 2010-11-18 | 2015-04-28 | Biolyph, Llc | Reagent preparation and dispensing device |
| MX2013008031A (es) | 2011-01-10 | 2014-05-13 | Byeong Seon Chang | Dispositivo de reconstitucion de medicamento compacto y metodo. |
| RU2464967C2 (ru) * | 2011-01-11 | 2012-10-27 | Общество с ограниченной ответственностью Структура Ко | Способ извлечения вещества из тонкодисперсной системы |
| EP2667856B9 (en) * | 2011-01-24 | 2021-12-01 | Otsuka Pharmaceutical Co., Ltd. | Medical device containing a cake composition comprising aripiprazole as an active ingredient, and a cake composition comprising aripiprazole as an active ingredient |
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-
1999
- 1999-10-13 FR FR9912748A patent/FR2799654B1/fr not_active Expired - Fee Related
-
2000
- 2000-10-05 AR ARP000105248A patent/AR025958A1/es active IP Right Grant
- 2000-10-10 EP EP00967987A patent/EP1223999B1/fr not_active Expired - Lifetime
- 2000-10-10 NZ NZ518286A patent/NZ518286A/en not_active IP Right Cessation
- 2000-10-10 AT AT00967987T patent/ATE327789T1/de not_active IP Right Cessation
- 2000-10-10 KR KR1020027004568A patent/KR100848722B1/ko not_active Expired - Lifetime
- 2000-10-10 DE DE60028401T patent/DE60028401T2/de not_active Expired - Lifetime
- 2000-10-10 ES ES00967987T patent/ES2261244T3/es not_active Expired - Lifetime
- 2000-10-10 AU AU77964/00A patent/AU7796400A/en not_active Abandoned
- 2000-10-10 WO PCT/FR2000/002804 patent/WO2001026718A1/fr not_active Ceased
- 2000-10-10 CN CN008141274A patent/CN1216657C/zh not_active Expired - Lifetime
- 2000-10-10 PL PL355150A patent/PL203757B1/pl unknown
- 2000-10-10 CZ CZ20021291A patent/CZ302559B6/cs not_active IP Right Cessation
- 2000-10-10 IL IL14889700A patent/IL148897A0/xx active IP Right Grant
- 2000-10-10 JP JP2001529779A patent/JP4394325B2/ja not_active Expired - Lifetime
- 2000-10-10 HU HU0203515A patent/HU226437B1/hu unknown
- 2000-10-10 US US10/110,362 patent/US6902543B1/en not_active Expired - Lifetime
- 2000-10-10 CA CA002386160A patent/CA2386160C/fr not_active Expired - Lifetime
- 2000-10-10 RU RU2002109442/14A patent/RU2258537C2/ru active
-
2002
- 2002-03-26 IL IL148897A patent/IL148897A/en unknown
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2004
- 2004-10-21 US US10/969,833 patent/US20050075602A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050075602A1 (en) | 2005-04-07 |
| IL148897A (en) | 2006-12-31 |
| HUP0203515A2 (en) | 2003-03-28 |
| KR20020042709A (ko) | 2002-06-05 |
| ATE327789T1 (de) | 2006-06-15 |
| CZ302559B6 (cs) | 2011-07-13 |
| KR100848722B1 (ko) | 2008-07-25 |
| AR025958A1 (es) | 2002-12-26 |
| JP4394325B2 (ja) | 2010-01-06 |
| AU7796400A (en) | 2001-04-23 |
| ES2261244T3 (es) | 2006-11-16 |
| CN1378466A (zh) | 2002-11-06 |
| CA2386160A1 (fr) | 2001-04-19 |
| WO2001026718A1 (fr) | 2001-04-19 |
| DE60028401D1 (de) | 2006-07-06 |
| RU2258537C2 (ru) | 2005-08-20 |
| CN1216657C (zh) | 2005-08-31 |
| IL148897A0 (en) | 2002-09-12 |
| EP1223999A1 (fr) | 2002-07-24 |
| CA2386160C (fr) | 2009-09-01 |
| NZ518286A (en) | 2004-06-25 |
| FR2799654A1 (fr) | 2001-04-20 |
| HK1050495A1 (en) | 2003-06-27 |
| EP1223999B1 (fr) | 2006-05-31 |
| FR2799654B1 (fr) | 2002-01-11 |
| PL355150A1 (en) | 2004-04-05 |
| CZ20021291A3 (cs) | 2003-04-16 |
| HU226437B1 (en) | 2008-12-29 |
| US6902543B1 (en) | 2005-06-07 |
| PL203757B1 (pl) | 2009-11-30 |
| JP2003511159A (ja) | 2003-03-25 |
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Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR |