DE69623268T2 - Vorgefüllte spritze zur verabreichung von medikamenten - Google Patents

Vorgefüllte spritze zur verabreichung von medikamenten

Info

Publication number
DE69623268T2
DE69623268T2 DE69623268T DE69623268T DE69623268T2 DE 69623268 T2 DE69623268 T2 DE 69623268T2 DE 69623268 T DE69623268 T DE 69623268T DE 69623268 T DE69623268 T DE 69623268T DE 69623268 T2 DE69623268 T2 DE 69623268T2
Authority
DE
Germany
Prior art keywords
syringe assembly
diluent
syringe
drug
assemblies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69623268T
Other languages
English (en)
Other versions
DE69623268D1 (de
Inventor
Richard W Grabenkort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69623268D1 publication Critical patent/DE69623268D1/de
Application granted granted Critical
Publication of DE69623268T2 publication Critical patent/DE69623268T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3101Leak prevention means for proximal end of syringes, i.e. syringe end opposite to needle mounting end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104Caps for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106Plugs for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3117Means preventing contamination of the medicament compartment of a syringe
    • A61M2005/3121Means preventing contamination of the medicament compartment of a syringe via the proximal end of a syringe, i.e. syringe end opposite to needle cannula mounting end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3128Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A61M2005/31506Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit formed as a single piece, e.g. moulded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/288Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3134Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515Connection of piston with piston rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/347Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
    • A61M5/502Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston
DE69623268T 1995-03-22 1996-03-21 Vorgefüllte spritze zur verabreichung von medikamenten Expired - Fee Related DE69623268T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40843695A 1995-03-22 1995-03-22
US08/616,798 US5785682A (en) 1995-03-22 1996-03-15 Pre-filled syringe drug delivery system
PCT/US1996/003913 WO1996029106A2 (en) 1995-03-22 1996-03-21 Pre-filled syringe drug delivery system

Publications (2)

Publication Number Publication Date
DE69623268D1 DE69623268D1 (de) 2002-10-02
DE69623268T2 true DE69623268T2 (de) 2003-04-17

Family

ID=27020273

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69623268T Expired - Fee Related DE69623268T2 (de) 1995-03-22 1996-03-21 Vorgefüllte spritze zur verabreichung von medikamenten

Country Status (11)

Country Link
US (1) US5785682A (de)
EP (1) EP0817654B1 (de)
JP (1) JP3803933B2 (de)
AT (1) ATE222784T1 (de)
AU (1) AU696759B2 (de)
CA (1) CA2215912C (de)
DE (1) DE69623268T2 (de)
DK (1) DK0817654T3 (de)
ES (1) ES2184856T3 (de)
PT (1) PT817654E (de)
WO (1) WO1996029106A2 (de)

Families Citing this family (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876372A (en) * 1995-03-22 1999-03-02 Abbott Laboratories Syringe system accomodating seperate prefilled barrels for two constituents
AU738397B2 (en) * 1995-03-29 2001-09-20 Abbott Laboratories Syringe system accommodating separate prefilled barrels for two constituents
EP0936934A1 (de) * 1996-09-27 1999-08-25 Abbott Laboratories Spritzenvorrichtung bestehend aus getrennten vorgefüllten zylindern für zwei komponenten
US6149626A (en) * 1997-10-03 2000-11-21 Bachynsky; Nicholas Automatic injecting syringe apparatus
CA2350706A1 (en) 1998-11-13 2000-05-25 Elan Pharma International Limited Drug delivery systems and methods
AU2759500A (en) * 1999-02-10 2000-08-29 Sub-Q Inc. Device and method for facilitating hemostasis of a biopsy tract
AU2997500A (en) * 1999-02-16 2000-09-04 Prismedical Corporation Single dose delivery device
AU5774500A (en) * 1999-06-30 2001-01-31 Baxter International Inc. Syringe for transfer of medication from a prefilled medication container
JP2001112867A (ja) * 1999-10-18 2001-04-24 Terumo Corp 薬剤入りシリンジ
DE60111501T2 (de) * 2000-02-23 2006-05-18 Hospira, Inc., Lake Forest Spritzen und spritzsysteme zur selektiven verabreichung von kontrollierten mengen einer therapeutischen substanz
SE0001894D0 (sv) * 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab Medical device
US6740062B2 (en) * 2000-05-22 2004-05-25 Pharmacia Ab Medical device
US6432089B1 (en) * 2000-06-21 2002-08-13 Medrad, Inc. Medical syringe
AUPQ867900A0 (en) 2000-07-10 2000-08-03 Medrad, Inc. Medical injector system
DE10044545A1 (de) * 2000-09-05 2002-04-04 Roland Bodmeier Retardpartikeldispersion
US6511459B1 (en) * 2000-09-29 2003-01-28 Mallinckrodt Inc. Syringe plunger having an improved sealing ability
JP2004525379A (ja) * 2001-05-04 2004-08-19 プリスメディカル コーポレーション 受動撹拌機能付デュアルチャンバ分解容器
US20030032935A1 (en) * 2001-08-10 2003-02-13 Scimed Life Systems, Inc. Packages facilitating convenient mixing and delivery of liquids
US9226876B2 (en) * 2001-10-19 2016-01-05 The Goodyear Tire & Rubber Company Rubber for baby bottle nipples, pacifiers, and syringe plungers
US6871751B2 (en) * 2001-10-19 2005-03-29 The Goodyear Tire & Rubber Company Rubber for baby bottle nipples, pacifiers, & syringe plungers
JP4152104B2 (ja) * 2001-12-28 2008-09-17 テルモ株式会社 シリンジおよびガスケット
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
WO2003105917A2 (en) 2002-06-12 2003-12-24 Scimed Life Systems, Inc. Bulking agents
GB0217285D0 (en) 2002-07-25 2002-09-04 Cambridge Consultants Syringes
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7135027B2 (en) * 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
FR2847887A1 (fr) * 2002-12-02 2004-06-04 Valois Sas Reservoir de produits fluides
WO2004080357A1 (es) 2003-03-14 2004-09-23 Ferreyro Irigoyen Roque Humber Dispositivo hidraulico de inyección de cemento oseo en la vertebroplastiá percutánea
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
US20050027255A1 (en) 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US8579908B2 (en) 2003-09-26 2013-11-12 DePuy Synthes Products, LLC. Device for delivering viscous material
US7666169B2 (en) 2003-11-25 2010-02-23 Medrad, Inc. Syringe and syringe plungers for use with medical injectors
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US6997910B2 (en) * 2004-05-03 2006-02-14 Infusive Technologies, Llc Multi-chamber, sequential dose dispensing syringe
US7998106B2 (en) 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
US7101354B2 (en) * 2004-05-03 2006-09-05 Infusive Technologies, Llc Mixing syringe with and without flush
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7294119B2 (en) * 2004-06-10 2007-11-13 Safety Syringes, Inc. Passive delivery system diluents mixing and delivery
CA2575699C (en) 2004-07-30 2014-07-08 Disc-O-Tech Medical Technologies Ltd. Methods, materials and apparatus for treating bone and other tissue
AT500930B1 (de) * 2004-10-25 2007-03-15 Pharma Consult Ges M B H & Co Verfahren und vorrichtung zum lyophilisieren, rekonstituieren und verabreichen eines rekonstituierten wirkstoffes
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
WO2006058435A2 (en) * 2004-12-03 2006-06-08 Duoject Medical Systems Inc. Cartridge, device and method for pharmaceutical storage, mixing and delivery
AU2005318948B2 (en) * 2004-12-24 2009-02-26 Collyn Patent Holdings Pty Ltd Safety syringe
US20060157507A1 (en) * 2004-12-30 2006-07-20 Chang Byeong S Multi-functional container closure delivery system
US7959600B2 (en) 2004-12-30 2011-06-14 Byeong S. Chang Container closure delivery system
US9463139B2 (en) 2004-12-30 2016-10-11 Byeong Seon Chang Compact medication reconstitution device and method
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
CN101175519A (zh) 2005-05-16 2008-05-07 马林克罗特公司 多级注射器及其使用方法
GB2426931A (en) * 2005-06-10 2006-12-13 Pa Knowledge Ltd Injection device
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
KR100738100B1 (ko) * 2006-01-19 2007-07-12 삼성전자주식회사 액체 시편의 예비 처리 및 주입 장치 및 방법
US8926569B2 (en) 2006-03-15 2015-01-06 Bayer Medical Care Inc. Plunger covers and plungers for use in syringes and methods of fabricating plunger covers and plungers for use in syringes
CN101478946B (zh) 2006-05-25 2013-11-06 拜耳医药保健有限公司 重构装置
WO2008032322A2 (en) 2006-09-14 2008-03-20 Depuy Spine, Inc. Bone cement and methods of use thereof
CA2747850C (en) * 2006-10-19 2013-05-14 Depuy Spine, Inc. Fluid delivery system
AU2015200078A1 (en) * 2006-10-19 2015-02-05 Depuy Spine, Inc. Fluid delivery system
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
USD1002840S1 (en) 2007-03-14 2023-10-24 Bayer Healthcare Llc Syringe plunger
USD942005S1 (en) 2007-03-14 2022-01-25 Bayer Healthcare Llc Orange syringe plunger cover
USD847985S1 (en) 2007-03-14 2019-05-07 Bayer Healthcare Llc Syringe plunger cover
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
CN101925373A (zh) * 2008-01-23 2010-12-22 马林克罗特公司 用于同轴针筒系统的柱塞适配器
US8105292B2 (en) 2008-02-11 2012-01-31 Safety Syringes, Inc. Reconstitution means for safety device
US9107668B2 (en) * 2008-03-25 2015-08-18 Cook Medical Technologies Llc Embolic particle mixing syringe
WO2009140511A1 (en) 2008-05-14 2009-11-19 J&J Solutions, Inc. Systems and methods for safe medicament transport
CA2724339C (en) * 2008-05-14 2017-08-01 Biolyph, Llc Reagent preparation and dispensing device and methods for the same
CA2730967C (en) 2008-07-18 2017-01-03 Becton, Dickinson And Company Cartridge stopper for an intradermal delivery system
WO2010019630A1 (en) * 2008-08-13 2010-02-18 Orizon Llc Suture passer
JP5815181B2 (ja) 2008-09-09 2015-11-17 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 注入ラインのプライミングを示すための装置
US8162875B2 (en) * 2008-09-30 2012-04-24 Tyco Healthcare Group Ip Diluent/medication mixing syringe assembly
US8454907B2 (en) * 2009-08-12 2013-06-04 Orogen Holdings, Llc Growth factor extractor
US8641661B2 (en) * 2010-01-05 2014-02-04 Baxter International Inc. Mixing system, kit and mixer adapter
EP2959880B1 (de) 2010-05-27 2017-04-12 J&J Solutions, Inc. Geschlossenes flüssigkeitstransfersystem
AU2011276396B2 (en) 2010-06-29 2014-05-08 Biolyph, Llc Reagent preparation assembly
US8919390B2 (en) 2010-11-18 2014-12-30 Biolyph, L.L.C. Reagent preparation and dispensing device
EP2508217B1 (de) * 2011-04-05 2019-09-04 Kpr U.S., Llc Anästhesiespritze
US8992505B2 (en) * 2011-04-18 2015-03-31 Thorne Consulting & Intellectual Property, LLC Medical syringe filling and valving
US9289562B2 (en) * 2011-04-18 2016-03-22 THORNE CONSULTING and INTELETUAL PROPERTY, LLC Pressure actuated valve for multi-chamber syringe applications
WO2012143494A1 (en) * 2011-04-20 2012-10-26 Novo Nordisk Health Care Ag Piston rod anchoring
WO2012158095A1 (en) * 2011-05-19 2012-11-22 Shl Group Ab Device for medicament delivery with syringe-like usability having a restraining mechanism
WO2013009897A1 (en) 2011-07-11 2013-01-17 Medpro Safety Products, Inc. Fluid delivery device and methods
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9022951B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9174003B2 (en) 2012-09-28 2015-11-03 Bayer Medical Care Inc. Quick release plunger
US9149576B2 (en) 2012-10-11 2015-10-06 Magnolia Medical Technologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination
DK2925391T3 (en) * 2012-11-30 2017-08-28 Unitract Syringe Pty Ltd COMBINING Piston Device for Dual Chamber Mixer
EP3884865B1 (de) 2012-11-30 2024-01-31 Magnolia Medical Technologies, Inc. Spritzenbasierter flüssigkeitsumleitungsmechanismus zur körperflüssigkeitsprobenahme
US10772548B2 (en) 2012-12-04 2020-09-15 Magnolia Medical Technologies, Inc. Sterile bodily-fluid collection device and methods
US20140296786A1 (en) * 2013-03-29 2014-10-02 Animas Corporation Fluid cartridge for medical infusion device
NZ716552A (en) 2013-08-02 2020-02-28 J&J Solutions Inc D B A Corvida Medical Compounding systems and methods for safe medicament transport
US20160296703A1 (en) * 2013-11-05 2016-10-13 3P Innovation Limited A Pharmaceutical Component-Mixing Delivery Assembly
US9676863B2 (en) 2014-02-10 2017-06-13 Merck Patent Gmbh Targeted TGFβ inhibitors
AU2015231396B2 (en) 2014-03-19 2018-12-06 Bayer Healthcare Llc System for syringe engagement to an injector
EP3131475A1 (de) * 2014-04-18 2017-02-22 Covidien LP Mischspritze
AU2015305638B2 (en) * 2014-08-18 2019-01-17 Windgap Medical, Inc Portable drug mixing and delivery device and associated methods
AU2015315285B2 (en) 2014-09-09 2019-04-04 Byeong Seon Chang Solution delivery device and method
USD831204S1 (en) 2015-03-02 2018-10-16 Neomed, Inc. Enteral syringe
USD831203S1 (en) 2015-03-02 2018-10-16 Neomed, Inc. Enteral syringe
USD807502S1 (en) 2015-03-02 2018-01-09 Neomed, Inc. Enteral syringe
US10624817B2 (en) 2015-03-24 2020-04-21 Neomed, Inc. Oral administration coupler for back-of-mouth delivery
JOP20200116A1 (ar) 2015-04-24 2017-06-16 Amgen Inc طرق لعلاج أو الوقاية من الصداع النصفي
EP4059426B1 (de) 2015-06-12 2023-12-13 Magnolia Medical Technologies, Inc. Vorrichtung zum spritzenbasierten fluidtransfer zur probenahme von körperflüssigkeiten
US10682287B2 (en) 2015-07-14 2020-06-16 Neomed, Inc. Dosing control coupling for enteral fluid transfer and enteral couplings and syringes
JP6694501B2 (ja) 2015-07-14 2020-05-13 ネオメッド,インクNeomed,Inc. 腸内液体流動用の投薬量制御継手
WO2017044252A1 (en) * 2015-09-11 2017-03-16 New Product Development Concepts Llc Telescoping syringe with one-way valve
US10800597B2 (en) * 2015-09-11 2020-10-13 New Product Development Concepts Llc Telescoping syringe with one-way valve
NZ740418A (en) 2015-09-17 2022-02-25 J&J Solutions Inc D B A Corvida Medical Medicament vial assembly
JP2018530396A (ja) 2015-10-13 2018-10-18 ジェイ アンド ジェイ ソリューションズ,インコーポレイテッド 閉鎖流体移動システムのための自動配合設備
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US10369292B2 (en) 2016-01-15 2019-08-06 W. L. Gore & Associates, Inc. Syringe plunger assemblies
JP6914913B2 (ja) * 2016-03-29 2021-08-04 テルモ株式会社 薬液投与器具、薬液投与器具の使用方法及び薬液投与器具の製造方法
JPWO2017170634A1 (ja) * 2016-03-30 2019-02-07 テルモ株式会社 シール部材、シリンジ組立体及びプレフィルドシリンジ
US9956143B2 (en) * 2016-06-14 2018-05-01 Pharmac, Llc Syringe apparatus for transferring liquids into and out of a vial having a septum
WO2018082887A1 (en) * 2016-11-01 2018-05-11 Sanofi-Aventis Deutschland Gmbh Feedback mechanism for an injection device
GB2556088A (en) * 2016-11-18 2018-05-23 Owen Mumford Ltd Packaging and devices for mixing medicament substances
CA3048646A1 (en) * 2017-01-07 2018-07-12 Merck Patent Gmbh Dosing regimens and dosage forms for targeted tgf-b inhibition
IL310711A (en) * 2017-01-10 2024-04-01 Intrexon Corp Modulation of expression of polypeptides through a new system for changing gene expression
ES2939951T3 (es) 2017-09-12 2023-04-28 Magnolia Medical Technologies Inc Sistema
WO2019092724A1 (en) 2017-11-09 2019-05-16 Medeviceng Syringe with dual nested chambers and method of use
JP7229267B2 (ja) 2017-12-07 2023-02-27 マグノリア メディカル テクノロジーズ,インコーポレイテッド 流体制御デバイスおよびその使用方法
DK3758777T3 (da) 2018-02-27 2023-02-27 Bayer Healthcare Llc Sprøjtestempelindgrebsmekanisme
KR102645455B1 (ko) * 2018-03-28 2024-03-07 카부시키가이샤 씨엠씨 이야쿠 2성분 혼합형 프리필드 시린지 키트
EA202092335A1 (ru) 2018-04-02 2021-01-22 Эмджен Инк. Композиции на основе эренумаба и пути их применения
US10959714B2 (en) * 2018-04-19 2021-03-30 Ethicon, Inc. Dual syringe cartridge and housing
US11491277B2 (en) 2018-08-13 2022-11-08 Monumedical, Llc Syringe with multi-stage filling and dispensing
CA3129065A1 (en) 2019-02-08 2020-08-13 Magnolia Medical Technologies, Inc. Devices and methods for bodily fluid collection and distribution
KR102157612B1 (ko) * 2019-03-05 2020-09-18 김용현 시린지, 약물 혼합 장치, 이를 포함하는 약물 혼합 키트 및 이를 제조하는 방법
CN113784793B (zh) 2019-03-11 2023-09-19 木兰医药技术股份有限公司 流体控制装置及其使用方法
JP7423089B2 (ja) * 2019-06-21 2024-01-29 クリーデンス メドシステムズ,インコーポレイテッド 注入システム
WO2023095094A1 (en) * 2021-11-29 2023-06-01 University Of Miami Ocular drug transfer and dispensing device

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2475939A (en) * 1946-07-12 1949-07-12 Applezweig Norman Cartridge syringe
US3489147A (en) * 1964-07-21 1970-01-13 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3477432A (en) * 1964-07-21 1969-11-11 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3255752A (en) * 1965-01-28 1966-06-14 Dick Peter Hypodermic syringe
US3838689A (en) * 1970-11-04 1974-10-01 M Cohen Disposable syringe with slit valve
US3757779A (en) * 1971-05-24 1973-09-11 Century Labor Inc Filter syringe
DE7128705U (de) * 1971-07-26 1971-10-28 Hampel H Steril verpackter spritzenzylinder einer einweg-injektionsspritze mit vom kolben loesbarer kolbenstange
US4153057A (en) * 1975-07-24 1979-05-08 Merck Patent Gesellschaft Mit Beschrankter Haftung Stopper for two-chamber mixing syringe
US4172457A (en) * 1977-10-06 1979-10-30 American Hospital Supply Corporation Plural component mixing system and method
US4185628A (en) * 1978-05-31 1980-01-29 Kopfer Rudolph J Compartmental syringe
US4581016A (en) * 1984-02-29 1986-04-08 Gettig Pharmaceutical Instrument Co. Dual cartridge wet/dry syringe
US5088996A (en) * 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
GB2203047B (en) * 1987-02-27 1991-01-30 Gilbert Henry Banks Single-use syringe
DE3816961A1 (de) * 1987-07-21 1989-02-02 Wasserburger Arzneimittelwerk Injektionsspritze fuer medizinische zwecke
US5067998A (en) * 1987-12-21 1991-11-26 General Electric Company Fibrous material-containing composite
US4957637A (en) * 1988-05-23 1990-09-18 Sherwood Medical Company Serum separator system for centrifuge with piercable membrane
FR2641191B2 (fr) * 1988-06-03 1991-03-15 Clotteau Jean Seringue a injection unique
US5407431A (en) * 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
US5135507A (en) * 1990-05-10 1992-08-04 Habley Medical Technology Corporation One-piece syringe
CA2016870C (en) * 1990-05-15 1994-03-29 Arnie Drudik Dispenser for storing and mixing several components
DK174390D0 (da) * 1990-07-20 1990-07-20 Novo Nordisk As Tokammersproejte
DK288590D0 (da) * 1990-12-04 1990-12-04 Michael Morris Blandings/oploesnings-sproejte til cytostatika for medicinsk behandling af cancer patienter
US5181909A (en) * 1991-05-15 1993-01-26 Mcfarlane Richard H Ampule-container medical syringe and methods
US5158546A (en) * 1991-08-07 1992-10-27 Habley Medical Technology Corp. Controlled action self-mixing vial
US5289858A (en) * 1991-12-18 1994-03-01 Abbott Laboratories System for accommodating withdrawal of liquid from a bulk supply
US5496288A (en) * 1992-09-23 1996-03-05 Becton, Dickinson And Company Protective cap for hypodermic syringe
JP3172005B2 (ja) * 1992-11-27 2001-06-04 株式会社大協精工 注射器兼容器
CA2150255C (en) * 1992-12-01 1999-08-03 Tetsuro Higashikawa Syringe
US5370621A (en) * 1992-12-14 1994-12-06 Mallinckrodt Medical, Inc. Insert device for facilitating limited aspiration of a delivery apparatus
US5298024A (en) * 1992-12-28 1994-03-29 Frank Richmond Multi-liquid medicament delivery system with reflex valves
US5520657A (en) * 1993-08-09 1996-05-28 Sellers; Jackie Method and device for vessel location cannulation utilizing a unique needle and syringe device
US5372586A (en) * 1993-10-20 1994-12-13 Habley Medical Technology Corp. Telescoping pharmaceutical storage and mixing syringe
US5569193A (en) * 1995-03-22 1996-10-29 Abbott Laboratories Syringe system accommodating separately storable prefilled containers for two constituents

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DE69623268D1 (de) 2002-10-02
PT817654E (pt) 2003-01-31
ES2184856T3 (es) 2003-04-16
WO1996029106A3 (en) 1996-10-24
CA2215912A1 (en) 1996-09-26
AU5258296A (en) 1996-10-08
JP3803933B2 (ja) 2006-08-02
ATE222784T1 (de) 2002-09-15
EP0817654B1 (de) 2002-08-28
EP0817654A2 (de) 1998-01-14
WO1996029106A2 (en) 1996-09-26
US5785682A (en) 1998-07-28
JPH11502731A (ja) 1999-03-09
DK0817654T3 (da) 2003-01-06
AU696759B2 (en) 1998-09-17

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