DE3715224C2 - Dosierungsform zur stoßweisen Freisetzung eines Arzneimittels - Google Patents

Dosierungsform zur stoßweisen Freisetzung eines Arzneimittels

Info

Publication number
DE3715224C2
DE3715224C2 DE3715224A DE3715224A DE3715224C2 DE 3715224 C2 DE3715224 C2 DE 3715224C2 DE 3715224 A DE3715224 A DE 3715224A DE 3715224 A DE3715224 A DE 3715224A DE 3715224 C2 DE3715224 C2 DE 3715224C2
Authority
DE
Germany
Prior art keywords
dosage form
preparation
layer
wall
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3715224A
Other languages
German (de)
English (en)
Other versions
DE3715224A1 (de
Inventor
Atul Devdatt Ayer
Felix Theeuwes
Patrick W-L Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE3715224A1 publication Critical patent/DE3715224A1/de
Application granted granted Critical
Publication of DE3715224C2 publication Critical patent/DE3715224C2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE3715224A 1986-05-09 1987-05-07 Dosierungsform zur stoßweisen Freisetzung eines Arzneimittels Expired - Lifetime DE3715224C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/861,188 US4842867A (en) 1986-05-09 1986-05-09 Pulsed drug delivery of doxylamine

Publications (2)

Publication Number Publication Date
DE3715224A1 DE3715224A1 (de) 1987-11-12
DE3715224C2 true DE3715224C2 (de) 1997-02-20

Family

ID=25335124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3715224A Expired - Lifetime DE3715224C2 (de) 1986-05-09 1987-05-07 Dosierungsform zur stoßweisen Freisetzung eines Arzneimittels

Country Status (14)

Country Link
US (1) US4842867A (enExample)
JP (2) JPS62298529A (enExample)
KR (1) KR950010144B1 (enExample)
AU (1) AU621030B2 (enExample)
BE (1) BE1000232A5 (enExample)
CA (1) CA1297368C (enExample)
CH (1) CH671696A5 (enExample)
DE (1) DE3715224C2 (enExample)
ES (1) ES2005571A6 (enExample)
FR (1) FR2598319B1 (enExample)
IT (1) IT1208883B (enExample)
NL (1) NL193308C (enExample)
SE (1) SE502684C2 (enExample)
ZA (1) ZA873091B (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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US5141752A (en) * 1986-05-09 1992-08-25 Alza Corporation Delayed drug delivery device
US4814181A (en) * 1987-09-03 1989-03-21 Alza Corporation Dosage form comprising fast agent delivery followed by slow agent delivery
IL88083A (en) * 1987-11-06 1992-11-15 Tanabe Seiyaku Co Controlled release pharmaceutical dosage form and its preparation
US4837111A (en) * 1988-03-21 1989-06-06 Alza Corporation Dosage form for dispensing drug for human therapy
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5067960A (en) * 1989-12-06 1991-11-26 Medtronic, Inc. Muscle fitness detection by colorimetry
US5045082A (en) * 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose
US5071607A (en) * 1990-01-31 1991-12-10 Alza Corporatino Method and apparatus for forming a hole in a drug dispensing device
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5190763A (en) * 1990-05-07 1993-03-02 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US6764697B1 (en) 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
US5190765A (en) * 1991-06-27 1993-03-02 Alza Corporation Therapy delayed
US5252338A (en) * 1991-06-27 1993-10-12 Alza Corporation Therapy delayed
US5160744A (en) * 1991-06-27 1992-11-03 Alza Corporation Verapmil therapy
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) * 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
ZA935569B (en) * 1992-07-31 1994-04-12 Daratech Pty Ltd Controlled release implants
US5391378A (en) * 1993-02-22 1995-02-21 Elizabeth-Hata International, Inc. Two-part medicinal tablet and method of manufacture
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US5718700A (en) * 1994-09-20 1998-02-17 Alza Corporation Exit means in dosage form
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US6096339A (en) * 1997-04-04 2000-08-01 Alza Corporation Dosage form, process of making and using same
ES2194210T3 (es) * 1996-08-16 2003-11-16 Alza Corp Forma de dosificacion para suministrar una dosis ascendente de farmaco.
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US5788987A (en) 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US6962997B1 (en) 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
DE69819351D1 (de) * 1997-09-11 2003-12-04 Nycomed Danmark As Roskilde Aus mehreren einzeleinheiten zusammengesetzte arzneimittel mit nicht-steroidalen wirkstoffen (nsaids)
US6372254B1 (en) * 1998-04-02 2002-04-16 Impax Pharmaceuticals Inc. Press coated, pulsatile drug delivery system suitable for oral administration
US6551613B1 (en) * 1998-09-08 2003-04-22 Alza Corporation Dosage form comprising therapeutic formulation
CN1227003C (zh) * 1998-09-09 2005-11-16 阿尔萨公司 包括液体制剂的剂型
RU2246295C2 (ru) * 1998-11-02 2005-02-20 Элзэ Копэрейшн Лекарственная форма c постоянной скоростью высвобождения лекарственного вещества, ядро лекарственной формы и способ обеспечения облегченного высвобождения лекарственного вещества из лекарственной формы
US6419960B1 (en) 1998-12-17 2002-07-16 Euro-Celtique S.A. Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
CA2440641A1 (en) * 2001-03-13 2002-09-19 Anand R. Baichwal Chronotherapeutic dosage forms containing glucocorticosteroid
US20030125714A1 (en) * 2001-12-18 2003-07-03 Edgren David Emil Dosage form for time-varying patterns of drug delivery
CN1606434A (zh) * 2001-12-19 2005-04-13 株式会社三和化学研究所 控制释放成型品
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
WO2004026361A1 (en) * 2002-09-18 2004-04-01 Medtronic Vascular, Inc. Controllable drug releasing gradient coatings for medical devices
TW200418527A (en) * 2002-10-31 2004-10-01 Alza Corp Dosage form providing ascending release of liquid formulation
AP2006003585A0 (en) * 2003-09-19 2006-04-30 Penwest Pharmaceuticals Co Delayed release dosage forms.
EP1663156A2 (en) * 2003-09-19 2006-06-07 Penwest Pharmaceuticals Company Chronotherapeutic dosage forms
DE102008059206A1 (de) * 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
WO2011057131A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Polysaccharide based hydrogels
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
PT3326611T (pt) 2012-02-22 2020-08-20 Duchesnay Inc Formulação de doxilamina e piridoxina e/ou seus metabolitos ou sais
WO2013123569A1 (en) * 2012-02-22 2013-08-29 Duchesnay Inc. Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof
US9452181B2 (en) 2013-07-22 2016-09-27 Duchesnay Inc. Composition for the management of nausea and vomiting
ES2670619T3 (es) 2013-07-22 2018-05-31 Duchesnay Inc. Composición para la gestión de náuseas y vómitos
TWI595874B (zh) 2014-08-29 2017-08-21 達契斯奈股份有限公司 多西拉敏及吡哆醇及／或其代謝產物或鹽之多模式釋放調配物
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
JP6878417B2 (ja) * 2016-02-17 2021-05-26 トリアステック インコーポレイテッド 剤形およびそれらの使用
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4235236A (en) * 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
US4320759A (en) * 1980-04-28 1982-03-23 Alza Corporation Dispenser with diffuser
US4309996A (en) * 1980-04-28 1982-01-12 Alza Corporation System with microporous releasing diffusor
US4298003A (en) * 1980-05-12 1981-11-03 Alza Corporation System for delivering agent at zero order rate with emerging agent below saturation
US4439196A (en) * 1982-03-18 1984-03-27 Merck & Co., Inc. Osmotic drug delivery system
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4576604A (en) * 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
GB2155889B (en) * 1984-03-21 1988-03-02 Alza Corp Dispenser-capsule
US4609374A (en) * 1985-04-22 1986-09-02 Alza Corporation Osmotic device comprising means for governing initial time of agent release therefrom

Also Published As

Publication number Publication date
JPH07116018B2 (ja) 1995-12-13
KR870010866A (ko) 1987-12-18
FR2598319B1 (fr) 1989-12-01
BE1000232A5 (fr) 1988-09-20
AU621030B2 (en) 1992-03-05
KR950010144B1 (ko) 1995-09-11
CH671696A5 (enExample) 1989-09-29
DE3715224A1 (de) 1987-11-12
FR2598319A1 (fr) 1987-11-13
SE8701900D0 (sv) 1987-05-08
AU7183787A (en) 1987-11-12
JPS62267221A (ja) 1987-11-19
JPS62298529A (ja) 1987-12-25
ES2005571A6 (es) 1989-03-16
NL8701102A (nl) 1987-12-01
IT8767393A0 (it) 1987-05-07
SE8701900L (sv) 1987-11-10
ZA873091B (en) 1987-12-30
IT1208883B (it) 1989-07-10
US4842867A (en) 1989-06-27
NL193308C (nl) 1999-06-02
CA1297368C (en) 1992-03-17
NL193308B (nl) 1999-02-01
SE502684C2 (sv) 1995-12-11

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition