ES2005571A6 - Una forma de dosificacion para la descarga de un formulado de farmaco beneficioso a un entorno de uso - Google Patents
Una forma de dosificacion para la descarga de un formulado de farmaco beneficioso a un entorno de usoInfo
- Publication number
- ES2005571A6 ES2005571A6 ES8701370A ES8701370A ES2005571A6 ES 2005571 A6 ES2005571 A6 ES 2005571A6 ES 8701370 A ES8701370 A ES 8701370A ES 8701370 A ES8701370 A ES 8701370A ES 2005571 A6 ES2005571 A6 ES 2005571A6
- Authority
- ES
- Spain
- Prior art keywords
- doxylamine
- drug delivery
- pulsed drug
- drug
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Abstract
COMPRENDE: A) UNA PARED SEMIPERMEABLE QUE RODEA Y DEFINE A; B) UN COMPARTIMENTO; C) UNA PRIMERA CAPA QUE INCLUYE UN FORMULADO DE FARMACO BENEFICIOSO EN EL COMPARTIMENTO; D) UNA SEGUNDA CAPA QUE COMPRENDE UNA COMPOSICION DE HIDROGEL; E) MEDIOS PARA RETARDAR LA LIBERACION DEL FORMULADO DE FARMACO DESDE EL COMPARTIMENTO Y F) POR LO MENOS UNA SALIDA EN LA PARED QUE COMUNICA EL EXTERIOR CON EL COMPARTIMENTO. ESTA FORMA DE DOSIFICACION ES UTIL PARA LA DESCARGA PULSANTE DE UN FARMACO BENEFICIOSO, SIENDO CAPAZ DE DESCARGAR UN PRIMER IMPULSO O DOSIS INICIAL DE FARMACO SEGUIDO DE UN IMPULSO O DOSIS RETARDADA DE FARMACO.LA FIGURA ADJUNTA ES UNA VISTA ABIERTA DE UNA FORMA DE DOSIFICACION QUE RETARDA LA ADMINISTRACION PULSATIL DE UNA DOSIS DE FARMACO AL TUBO GASTROINTESTINAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/861,188 US4842867A (en) | 1986-05-09 | 1986-05-09 | Pulsed drug delivery of doxylamine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2005571A6 true ES2005571A6 (es) | 1989-03-16 |
Family
ID=25335124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8701370A Expired ES2005571A6 (es) | 1986-05-09 | 1987-05-07 | Una forma de dosificacion para la descarga de un formulado de farmaco beneficioso a un entorno de uso |
Country Status (14)
Country | Link |
---|---|
US (1) | US4842867A (es) |
JP (2) | JPS62298529A (es) |
KR (1) | KR950010144B1 (es) |
AU (1) | AU621030B2 (es) |
BE (1) | BE1000232A5 (es) |
CA (1) | CA1297368C (es) |
CH (1) | CH671696A5 (es) |
DE (1) | DE3715224C2 (es) |
ES (1) | ES2005571A6 (es) |
FR (1) | FR2598319B1 (es) |
IT (1) | IT1208883B (es) |
NL (1) | NL193308C (es) |
SE (1) | SE502684C2 (es) |
ZA (1) | ZA873091B (es) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141752A (en) * | 1986-05-09 | 1992-08-25 | Alza Corporation | Delayed drug delivery device |
US4814181A (en) * | 1987-09-03 | 1989-03-21 | Alza Corporation | Dosage form comprising fast agent delivery followed by slow agent delivery |
IL88083A (en) * | 1987-11-06 | 1992-11-15 | Tanabe Seiyaku Co | Controlled release pharmaceutical dosage form and its preparation |
US4837111A (en) * | 1988-03-21 | 1989-06-06 | Alza Corporation | Dosage form for dispensing drug for human therapy |
IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Hydrogel-operated release devices |
US5200197A (en) * | 1989-11-16 | 1993-04-06 | Alza Corporation | Contraceptive pill |
US5067960A (en) * | 1989-12-06 | 1991-11-26 | Medtronic, Inc. | Muscle fitness detection by colorimetry |
US5045082A (en) * | 1990-01-10 | 1991-09-03 | Alza Corporation | Long-term delivery device including loading dose |
US5071607A (en) * | 1990-01-31 | 1991-12-10 | Alza Corporatino | Method and apparatus for forming a hole in a drug dispensing device |
US5324280A (en) * | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
US5190763A (en) * | 1990-05-07 | 1993-03-02 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
US6764697B1 (en) | 1991-06-27 | 2004-07-20 | Alza Corporation | System for delaying drug delivery up to seven hours |
US5252338A (en) * | 1991-06-27 | 1993-10-12 | Alza Corporation | Therapy delayed |
US5160744A (en) * | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
US5190765A (en) * | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
US5209746A (en) * | 1992-02-18 | 1993-05-11 | Alza Corporation | Osmotically driven delivery devices with pulsatile effect |
US5308348A (en) * | 1992-02-18 | 1994-05-03 | Alza Corporation | Delivery devices with pulsatile effect |
US5456679A (en) * | 1992-02-18 | 1995-10-10 | Alza Corporation | Delivery devices with pulsatile effect |
US5221278A (en) * | 1992-03-12 | 1993-06-22 | Alza Corporation | Osmotically driven delivery device with expandable orifice for pulsatile delivery effect |
CA2141459A1 (en) * | 1992-07-31 | 1994-02-17 | Richard Yu | Controlled release implants |
US5391378A (en) * | 1993-02-22 | 1995-02-21 | Elizabeth-Hata International, Inc. | Two-part medicinal tablet and method of manufacture |
US6440457B1 (en) * | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
US5718700A (en) * | 1994-09-20 | 1998-02-17 | Alza Corporation | Exit means in dosage form |
US5837284A (en) | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
US6096339A (en) * | 1997-04-04 | 2000-08-01 | Alza Corporation | Dosage form, process of making and using same |
AU3909597A (en) * | 1996-08-16 | 1998-03-06 | Alza Corporation | Dosage form for providing ascending dose of drug |
US6919373B1 (en) | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
US5788987A (en) | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
US6962997B1 (en) | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
NZ503086A (en) * | 1997-08-29 | 2002-03-01 | Upjohn Co | An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes |
US6599529B1 (en) * | 1997-09-11 | 2003-07-29 | Nycomed Danmark A/S | Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs) |
US6372254B1 (en) * | 1998-04-02 | 2002-04-16 | Impax Pharmaceuticals Inc. | Press coated, pulsatile drug delivery system suitable for oral administration |
US6551613B1 (en) * | 1998-09-08 | 2003-04-22 | Alza Corporation | Dosage form comprising therapeutic formulation |
EP1112060B1 (en) * | 1998-09-09 | 2005-12-07 | ALZA Corporation | Dosage form comprising liquid formulation |
CN1325301A (zh) * | 1998-11-02 | 2001-12-05 | 阿尔扎有限公司 | 活性物质的控制释放 |
US6419960B1 (en) | 1998-12-17 | 2002-07-16 | Euro-Celtique S.A. | Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations |
JP2004529902A (ja) * | 2001-03-13 | 2004-09-30 | ペンウェスト ファーマシューティカルズ カンパニー | グルココルチコステロイドを含有する時間治療(chronotherapeutic)投与形態 |
EP1492509A1 (en) * | 2001-12-18 | 2005-01-05 | ALZA Corporation | Dosage form providing time-varying patterns of drug delivery |
JP4417110B2 (ja) * | 2001-12-19 | 2010-02-17 | 株式会社三和化学研究所 | 放出制御型成型品 |
US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
US20050208132A1 (en) * | 2002-07-29 | 2005-09-22 | Gayatri Sathyan | Methods and dosage forms for reducing side effects of benzisozazole derivatives |
EP1539270A1 (en) * | 2002-09-18 | 2005-06-15 | Medtronic Vascular, Inc. | Controllable drug releasing gradient coatings for medical devices |
AU2003287301A1 (en) * | 2002-10-31 | 2004-06-07 | Alza Corporation | Dosage form providing ascending release of liquid formulation |
CN1882316A (zh) * | 2003-09-19 | 2006-12-20 | 宾韦斯特医药公司 | 延迟释放剂型 |
US20050118267A1 (en) * | 2003-09-19 | 2005-06-02 | Penwest Pharmaceuticals Co. | Chronotherapeutic dosage forms |
DE102008059206A1 (de) * | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
US8795727B2 (en) | 2009-11-09 | 2014-08-05 | Spotlight Technology Partners Llc | Fragmented hydrogels |
US9700650B2 (en) | 2009-11-09 | 2017-07-11 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
WO2013123569A1 (en) * | 2012-02-22 | 2013-08-29 | Duchesnay Inc. | Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof |
AU2013224598B2 (en) | 2012-02-22 | 2015-09-17 | Duchesnay Inc. | Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof |
US9452181B2 (en) | 2013-07-22 | 2016-09-27 | Duchesnay Inc. | Composition for the management of nausea and vomiting |
PL3024466T3 (pl) | 2013-07-22 | 2018-08-31 | Duchesnay Inc. | Kompozycja do kontrolowania nudności i wymiotów |
US9526703B2 (en) | 2014-08-29 | 2016-12-27 | Duchesnay Inc. | Plurimodal release formulation of doxylamine and pyridoxine and/or metabolites or salts thereof |
CA3018328A1 (en) | 2014-10-31 | 2016-04-30 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4200098A (en) * | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
US4235236A (en) * | 1979-02-12 | 1980-11-25 | Alza Corporation | Device for dispensing drug by combined diffusional and osmotic operations |
US4309996A (en) * | 1980-04-28 | 1982-01-12 | Alza Corporation | System with microporous releasing diffusor |
US4320759A (en) * | 1980-04-28 | 1982-03-23 | Alza Corporation | Dispenser with diffuser |
US4298003A (en) * | 1980-05-12 | 1981-11-03 | Alza Corporation | System for delivering agent at zero order rate with emerging agent below saturation |
US4439196A (en) * | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
US4576604A (en) * | 1983-03-04 | 1986-03-18 | Alza Corporation | Osmotic system with instant drug availability |
GB2155889B (en) * | 1984-03-21 | 1988-03-02 | Alza Corp | Dispenser-capsule |
US4609374A (en) * | 1985-04-22 | 1986-09-02 | Alza Corporation | Osmotic device comprising means for governing initial time of agent release therefrom |
-
1986
- 1986-05-09 US US06/861,188 patent/US4842867A/en not_active Expired - Lifetime
- 1986-06-13 JP JP61138043A patent/JPS62298529A/ja active Pending
-
1987
- 1987-04-22 AU AU71837/87A patent/AU621030B2/en not_active Expired
- 1987-04-29 ZA ZA873091A patent/ZA873091B/xx unknown
- 1987-04-29 CH CH1626/87A patent/CH671696A5/de not_active IP Right Cessation
- 1987-05-01 KR KR1019870004291A patent/KR950010144B1/ko not_active IP Right Cessation
- 1987-05-07 FR FR878706454A patent/FR2598319B1/fr not_active Expired
- 1987-05-07 ES ES8701370A patent/ES2005571A6/es not_active Expired
- 1987-05-07 CA CA000536577A patent/CA1297368C/en not_active Expired - Lifetime
- 1987-05-07 DE DE3715224A patent/DE3715224C2/de not_active Expired - Lifetime
- 1987-05-07 IT IT8767393A patent/IT1208883B/it active
- 1987-05-08 SE SE8701900A patent/SE502684C2/sv not_active IP Right Cessation
- 1987-05-08 JP JP62112242A patent/JPH07116018B2/ja not_active Expired - Fee Related
- 1987-05-08 BE BE8700503A patent/BE1000232A5/fr not_active IP Right Cessation
- 1987-05-08 NL NL8701102A patent/NL193308C/nl not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3715224A1 (de) | 1987-11-12 |
FR2598319A1 (fr) | 1987-11-13 |
KR870010866A (ko) | 1987-12-18 |
SE8701900L (sv) | 1987-11-10 |
FR2598319B1 (fr) | 1989-12-01 |
AU7183787A (en) | 1987-11-12 |
JPS62267221A (ja) | 1987-11-19 |
CH671696A5 (es) | 1989-09-29 |
KR950010144B1 (ko) | 1995-09-11 |
SE8701900D0 (sv) | 1987-05-08 |
DE3715224C2 (de) | 1997-02-20 |
JPS62298529A (ja) | 1987-12-25 |
NL193308C (nl) | 1999-06-02 |
JPH07116018B2 (ja) | 1995-12-13 |
IT8767393A0 (it) | 1987-05-07 |
US4842867A (en) | 1989-06-27 |
NL8701102A (nl) | 1987-12-01 |
BE1000232A5 (fr) | 1988-09-20 |
CA1297368C (en) | 1992-03-17 |
ZA873091B (en) | 1987-12-30 |
NL193308B (nl) | 1999-02-01 |
AU621030B2 (en) | 1992-03-05 |
IT1208883B (it) | 1989-07-10 |
SE502684C2 (sv) | 1995-12-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20070508 |