US5266331A
(en)
*
|
1991-11-27 |
1993-11-30 |
Euroceltique, S.A. |
Controlled release oxycodone compositions
|
US5968551A
(en)
*
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US20080075781A1
(en)
*
|
1992-11-25 |
2008-03-27 |
Purdue Pharma Lp |
Controlled release oxycodone compositions
|
US20070275062A1
(en)
*
|
1993-06-18 |
2007-11-29 |
Benjamin Oshlack |
Controlled release oxycodone compositions
|
US7740881B1
(en)
|
1993-07-01 |
2010-06-22 |
Purdue Pharma Lp |
Method of treating humans with opioid formulations having extended controlled release
|
IL110014A
(en)
*
|
1993-07-01 |
1999-11-30 |
Euro Celtique Sa |
Solid controlled-release oral dosage forms of opioid analgesics
|
US5879705A
(en)
*
|
1993-07-27 |
1999-03-09 |
Euro-Celtique S.A. |
Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
|
US5460826A
(en)
*
|
1994-06-27 |
1995-10-24 |
Alza Corporation |
Morphine therapy
|
US5914131A
(en)
*
|
1994-07-07 |
1999-06-22 |
Alza Corporation |
Hydromorphone therapy
|
US20020006438A1
(en)
*
|
1998-09-25 |
2002-01-17 |
Benjamin Oshlack |
Sustained release hydromorphone formulations exhibiting bimodal characteristics
|
GB9519363D0
(en)
|
1995-09-22 |
1995-11-22 |
Euro Celtique Sa |
Pharmaceutical formulation
|
DE19607395C2
(de)
*
|
1996-02-28 |
2002-11-21 |
Lohmann Therapie Syst Lts |
Salze aus einem kationischen narkotischen Analgetikum mit einem anionischen nichtnarkotischen Analgetikum, Verfahren zu deren Herstellung und die diese Salze enthaltenden pharmazeutischen Präparate
|
DK0914097T3
(da)
*
|
1996-03-12 |
2002-04-29 |
Alza Corp |
Sammensætning og doseringsform omfattende opioid antagonist
|
US5948787A
(en)
*
|
1997-02-28 |
1999-09-07 |
Alza Corporation |
Compositions containing opiate analgesics
|
US6066339A
(en)
*
|
1997-10-17 |
2000-05-23 |
Elan Corporation, Plc |
Oral morphine multiparticulate formulation
|
PT1685839E
(pt)
|
1997-12-22 |
2013-07-08 |
Euro Celtique Sa |
Forma de dosagem farmacêutica por via oral compreendendo uma combinação de um agonista opióide e de um antagonista opióide
|
US8524277B2
(en)
*
|
1998-03-06 |
2013-09-03 |
Alza Corporation |
Extended release dosage form
|
US6806294B2
(en)
|
1998-10-15 |
2004-10-19 |
Euro-Celtique S.A. |
Opioid analgesic
|
FR2794646B1
(fr)
|
1999-06-09 |
2001-09-21 |
Ethypharm Lab Prod Ethiques |
Microgranules de sulfate de morphine, procede de preparation et composition les contenant
|
US6451806B2
(en)
|
1999-09-29 |
2002-09-17 |
Adolor Corporation |
Methods and compositions involving opioids and antagonists thereof
|
KR20130010512A
(ko)
|
1999-10-29 |
2013-01-28 |
유로-셀티크 소시에떼 아노뉨 |
서방성 하이드로코돈 제형
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
US6469030B2
(en)
|
1999-11-29 |
2002-10-22 |
Adolor Corporation |
Methods for the treatment and prevention of ileus
|
AP1665A
(en)
|
2000-02-08 |
2006-09-22 |
Euro Celtique Sa |
Tamper-resistant oral opioid agonist formulations.
|
US20020013331A1
(en)
*
|
2000-06-26 |
2002-01-31 |
Williams Robert O. |
Methods and compositions for treating pain of the mucous membrane
|
KR100968128B1
(ko)
|
2000-10-30 |
2010-07-06 |
유로-셀티크 소시에떼 아노뉨 |
서방성 하이드로코돈 제형
|
SE0004671D0
(sv)
*
|
2000-12-15 |
2000-12-15 |
Amarin Dev Ab |
Pharmaceutical formulation
|
UA81224C2
(uk)
*
|
2001-05-02 |
2007-12-25 |
Euro Celtic S A |
Дозована форма оксикодону та її застосування
|
US20110104214A1
(en)
|
2004-04-15 |
2011-05-05 |
Purdue Pharma L.P. |
Once-a-day oxycodone formulations
|
CN1525851A
(zh)
|
2001-05-11 |
2004-09-01 |
������ҩ������˾ |
抗滥用阿片样物质控释剂型
|
JP4256259B2
(ja)
|
2001-07-18 |
2009-04-22 |
ユーロ−セルティーク エス.エイ. |
オキシコドン及びナロキソンの医薬配合物
|
RU2004106619A
(ru)
|
2001-08-06 |
2005-07-10 |
Эро-Селтик С.А. (Lu) |
Композиции опиоидного агониста, содержащие высвобождаемый и изолированный антагонист
|
AU2002324624A1
(en)
|
2001-08-06 |
2003-02-24 |
Euro-Celtique S.A. |
Sequestered antagonist formulations
|
US20030068375A1
(en)
|
2001-08-06 |
2003-04-10 |
Curtis Wright |
Pharmaceutical formulation containing gelling agent
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
EP2957281A1
(de)
|
2001-09-21 |
2015-12-23 |
Egalet Ltd. |
Polymer-freigabe-system
|
WO2003024430A1
(en)
|
2001-09-21 |
2003-03-27 |
Egalet A/S |
Morphine polymer release system
|
CN100411611C
(zh)
|
2002-04-05 |
2008-08-20 |
欧洲凯尔蒂克公司 |
用于持续,不变且独立释放活性化合物的基质
|
US7776314B2
(en)
*
|
2002-06-17 |
2010-08-17 |
Grunenthal Gmbh |
Abuse-proofed dosage system
|
US10004729B2
(en)
|
2002-07-05 |
2018-06-26 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
US8557291B2
(en)
*
|
2002-07-05 |
2013-10-15 |
Collegium Pharmaceutical, Inc. |
Abuse-deterrent pharmaceutical compositions of opioids and other drugs
|
US8840928B2
(en)
|
2002-07-05 |
2014-09-23 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
JP4694207B2
(ja)
*
|
2002-07-05 |
2011-06-08 |
コルジウム ファーマシューティカル, インコーポレイテッド |
オピオイドおよび他の薬物に関する乱用抑止性の薬学的組成物
|
GB0218811D0
(en)
*
|
2002-08-14 |
2002-09-18 |
Cenes Ltd |
Salts of morphine-6-glucuronide
|
EP2422773A3
(de)
|
2002-09-20 |
2012-04-18 |
Alpharma, Inc. |
Sequestriermitteluntereinheit und zugehörige Zusammensetzungen und Verfahren
|
CA2498798A1
(en)
*
|
2002-09-20 |
2004-04-01 |
Alpharma, Inc. |
Sustained-release opioid formulations and methods of use
|
DE602004031096D1
(de)
|
2003-03-26 |
2011-03-03 |
Egalet As |
Morphin-system mit kontrollierter freisetzung
|
US20040202717A1
(en)
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
MY135852A
(en)
|
2003-04-21 |
2008-07-31 |
Euro Celtique Sa |
Pharmaceutical products
|
US6942003B2
(en)
*
|
2003-07-25 |
2005-09-13 |
Service Door Industries Limited |
Roll-up door curtain and guides and bottom bar therefor
|
DE102005005446A1
(de)
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Bruchfeste Darreichungsformen mit retardierter Freisetzung
|
US8075872B2
(en)
|
2003-08-06 |
2011-12-13 |
Gruenenthal Gmbh |
Abuse-proofed dosage form
|
DE102004032051A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
|
DE10361596A1
(de)
|
2003-12-24 |
2005-09-29 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
US20070048228A1
(en)
|
2003-08-06 |
2007-03-01 |
Elisabeth Arkenau-Maric |
Abuse-proofed dosage form
|
DE10336400A1
(de)
|
2003-08-06 |
2005-03-24 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte Darreichungsform
|
CA2540308C
(en)
|
2003-09-26 |
2013-08-06 |
Alza Corporation |
Drug coating providing high drug loading and methods for providing the same
|
ATE504288T1
(de)
*
|
2003-09-26 |
2011-04-15 |
Alza Corp |
Oros-push-stick für die kontrollierte abgabe von wirkstoffen
|
CN102697704A
(zh)
*
|
2003-09-26 |
2012-10-03 |
阿尔扎公司 |
阿片类与非阿片类镇痛药的控释制剂
|
US7201920B2
(en)
|
2003-11-26 |
2007-04-10 |
Acura Pharmaceuticals, Inc. |
Methods and compositions for deterring abuse of opioid containing dosage forms
|
EP1604666A1
(de)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
|
WO2005123039A1
(en)
|
2004-06-12 |
2005-12-29 |
Collegium Pharmaceutical, Inc. |
Abuse-deterrent drug formulations
|
DE102004032049A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte, orale Darreichungsform
|
US8541026B2
(en)
*
|
2004-09-24 |
2013-09-24 |
Abbvie Inc. |
Sustained release formulations of opioid and nonopioid analgesics
|
DE102005005449A1
(de)
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
EP1702558A1
(de)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Verfahren und Vorrichtung zur Darmtätigkeitserfassung
|
WO2007011972A2
(en)
*
|
2005-07-19 |
2007-01-25 |
Inverseon, Inc. |
Improved pharmacokinetic profile of beta-adrenergic inverse agonists for the treatment of pulmonary airway diseases
|
US20090317355A1
(en)
*
|
2006-01-21 |
2009-12-24 |
Abbott Gmbh & Co. Kg, |
Abuse resistant melt extruded formulation having reduced alcohol interaction
|
US20090022798A1
(en)
*
|
2007-07-20 |
2009-01-22 |
Abbott Gmbh & Co. Kg |
Formulations of nonopioid and confined opioid analgesics
|
US20100172989A1
(en)
*
|
2006-01-21 |
2010-07-08 |
Abbott Laboratories |
Abuse resistant melt extruded formulation having reduced alcohol interaction
|
US20070190141A1
(en)
*
|
2006-02-16 |
2007-08-16 |
Aaron Dely |
Extended release opiate composition
|
SI2034975T1
(sl)
|
2006-06-19 |
2012-07-31 |
Alpharma Pharmaceuticals Llc |
Farmacevtski sestavki
|
CA2671197A1
(en)
*
|
2006-07-21 |
2008-01-24 |
Lab International Srl |
Hydrophobic abuse deterrent delivery system
|
SA07280459B1
(ar)
|
2006-08-25 |
2011-07-20 |
بيورديو فارما إل. بي. |
أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
|
EP2104493A2
(de)
*
|
2007-01-16 |
2009-09-30 |
Egalet A/S |
Verwendung i) eines polyglycols und n) einer wirkstoffsubstanz zur herstellung einer pharmazeutischen zusammensetzung i) zur abschwächung des risikos alkoholbedingten dose-dumpings und/oder ii) zur reduzierung des risikos eines medikamentenmissbrauchs
|
DE102007011485A1
(de)
|
2007-03-07 |
2008-09-11 |
Grünenthal GmbH |
Darreichungsform mit erschwertem Missbrauch
|
CA2687192C
(en)
|
2007-06-04 |
2015-11-24 |
Egalet A/S |
Controlled release pharmaceutical compositions for prolonged effect
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
NZ586792A
(en)
|
2008-01-25 |
2012-09-28 |
Gruenenthal Chemie |
Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces
|
US9226907B2
(en)
|
2008-02-01 |
2016-01-05 |
Abbvie Inc. |
Extended release hydrocodone acetaminophen and related methods and uses thereof
|
WO2009121018A2
(en)
*
|
2008-03-27 |
2009-10-01 |
University Of Kentucky Research Foundation |
Opioid-nornicotine codrugs for pain management
|
US8710070B2
(en)
*
|
2008-03-27 |
2014-04-29 |
University Of Kentucky Research Foundation |
Opioid-ketamine and norketamine codrug combinations for pain management
|
ES2599031T3
(es)
|
2008-05-09 |
2017-01-31 |
Grünenthal GmbH |
Proceso para la preparación de una formulación de polvo intermedia y una forma de dosificación solida final utilizando un paso de congelación por pulverización
|
EP2393484A1
(de)
|
2009-02-06 |
2011-12-14 |
Egalet Ltd. |
Gegen missbrauch durch alkoholeinnahme widerstandsfähige zusammensetzung mit unmittelbarer freisetzung
|
NZ595663A
(en)
|
2009-03-10 |
2013-11-29 |
Euro Celtique Sa |
Immediate release pharmaceutical compositions comprising oxycodone and naloxone
|
FR2946533A1
(fr)
|
2009-06-12 |
2010-12-17 |
Ethypharm Sa |
Reduction des fluctuations plasmatiques d'opioides.
|
AU2010265213B2
(en)
|
2009-06-24 |
2012-08-23 |
Egalet Ltd. |
Controlled release formulations
|
AU2010275753B2
(en)
|
2009-07-22 |
2014-08-21 |
Grünenthal GmbH |
Hot-melt extruded controlled release dosage form
|
US20110020451A1
(en)
|
2009-07-22 |
2011-01-27 |
Grunenthal Gmbh |
Tamper-resistant dosage form for oxidation-sensitive opioids
|
CA2775890C
(en)
|
2009-09-30 |
2016-06-21 |
Acura Pharmaceuticals, Inc. |
Methods and compositions for deterring abuse
|
US10668060B2
(en)
|
2009-12-10 |
2020-06-02 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
WO2011095314A2
(en)
|
2010-02-03 |
2011-08-11 |
Grünenthal GmbH |
Preparation of a powdery pharmaceutical composition by means of an extruder
|
EP2611425B1
(de)
|
2010-09-02 |
2014-07-02 |
Grünenthal GmbH |
Manipulationssichere darreichungsform mit einem anionischen polymer
|
CN103269688A
(zh)
|
2010-09-02 |
2013-08-28 |
格吕伦塔尔有限公司 |
包含无机盐的抗破碎剂型
|
CN103370058A
(zh)
|
2010-12-22 |
2013-10-23 |
普渡制药公司 |
包覆的抗篡改控制释放剂型
|
EP2654733B1
(de)
|
2010-12-23 |
2016-04-06 |
Purdue Pharma LP |
Manipulationssichere feste orale darreichungsformen
|
ES2655900T3
(es)
|
2011-07-29 |
2018-02-22 |
Grünenthal GmbH |
Pastilla a prueba de manipulación que proporciona una liberación inmediata de un medicamento
|
HUE034710T2
(hu)
|
2011-07-29 |
2018-02-28 |
Gruenenthal Gmbh |
Visszaéléssel szemben ellenálló, azonnali hatóanyagfelszabadulást biztosító tabletta
|
WO2013127831A1
(en)
|
2012-02-28 |
2013-09-06 |
Grünenthal GmbH |
Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
|
SI2838512T1
(sl)
|
2012-04-18 |
2018-11-30 |
Gruenenthal Gmbh |
Pred posegi in prehitrim sproščanjem odporna farmacevtska oblika odmerka
|
US10064945B2
(en)
|
2012-05-11 |
2018-09-04 |
Gruenenthal Gmbh |
Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
|
BR112015000150A2
(pt)
|
2012-07-06 |
2017-06-27 |
Egalet Ltd |
composições farmacêuticas dissuasoras de abuso de liberação controlada
|
PL2872121T3
(pl)
|
2012-07-12 |
2019-02-28 |
SpecGx LLC |
Kompozycje farmaceutyczne o przedłużonym uwalnianiu, zniechęcające do nadużywania
|
CN107595793B
(zh)
|
2012-11-30 |
2020-11-13 |
阿库拉制药公司 |
活性药物成分的自调节释放
|
AU2014215478B2
(en)
|
2013-02-05 |
2018-09-13 |
Purdue Pharma L.P. |
Tamper resistant pharmaceutical formulations
|
US10751287B2
(en)
|
2013-03-15 |
2020-08-25 |
Purdue Pharma L.P. |
Tamper resistant pharmaceutical formulations
|
BR112015026549A2
(pt)
|
2013-05-29 |
2017-07-25 |
Gruenenthal Gmbh |
forma de dosagem à prova de violação contendo uma ou mais partículas
|
WO2014191396A1
(en)
|
2013-05-29 |
2014-12-04 |
Grünenthal GmbH |
Tamper resistant dosage form with bimodal release profile
|
CN105682643B
(zh)
|
2013-07-12 |
2019-12-13 |
格吕伦塔尔有限公司 |
含有乙烯-醋酸乙烯酯聚合物的防篡改剂型
|
CA2918004C
(en)
|
2013-07-23 |
2018-11-20 |
Euro-Celtique S.A. |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
MX371372B
(es)
|
2013-11-26 |
2020-01-28 |
Gruenenthal Gmbh |
Preparacion de una composicion farmaceutica en polvo por medio de criomolienda.
|
AU2015261060A1
(en)
|
2014-05-12 |
2016-11-03 |
Grunenthal Gmbh |
Tamper resistant immediate release capsule formulation comprising Tapentadol
|
US9872835B2
(en)
|
2014-05-26 |
2018-01-23 |
Grünenthal GmbH |
Multiparticles safeguarded against ethanolic dose-dumping
|
CA2975653A1
(en)
|
2015-02-03 |
2016-08-11 |
Grunenthal Gmbh |
Tamper-resistant dosage form comprising a polyethylene glycol graft copolymer
|
MX2017013637A
(es)
|
2015-04-24 |
2018-03-08 |
Gruenenthal Gmbh |
Forma de dosificacion resistente a alteraciones con liberacion inmediata y resistencia contra la extraccion por solventes.
|
WO2017040607A1
(en)
|
2015-08-31 |
2017-03-09 |
Acura Pharmaceuticals, Inc. |
Methods and compositions for self-regulated release of active pharmaceutical ingredient
|
JP2018526414A
(ja)
|
2015-09-10 |
2018-09-13 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護
|
WO2017222575A1
(en)
|
2016-06-23 |
2017-12-28 |
Collegium Pharmaceutical, Inc. |
Process of making more stable abuse-deterrent oral formulations
|
MX2020005438A
(es)
*
|
2017-12-20 |
2020-12-03 |
Purdue Pharma Lp |
Formas de dosificacion de sulfato de morfina disuasivas del abuso.
|