DE3706838C2 - Neue, physiologisch aktive Substanz, die einen Aldose-Reduktaseinhibitor darstellt, und Verfahren zu ihrer Herstellung - Google Patents

Neue, physiologisch aktive Substanz, die einen Aldose-Reduktaseinhibitor darstellt, und Verfahren zu ihrer Herstellung

Info

Publication number
DE3706838C2
DE3706838C2 DE3706838A DE3706838A DE3706838C2 DE 3706838 C2 DE3706838 C2 DE 3706838C2 DE 3706838 A DE3706838 A DE 3706838A DE 3706838 A DE3706838 A DE 3706838A DE 3706838 C2 DE3706838 C2 DE 3706838C2
Authority
DE
Germany
Prior art keywords
active substance
physiologically active
aldostatin
aqueous
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3706838A
Other languages
German (de)
English (en)
Other versions
DE3706838A1 (de
Inventor
Satoshi Yaginuma
Akira Asahi
Masaki Takada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Publication of DE3706838A1 publication Critical patent/DE3706838A1/de
Application granted granted Critical
Publication of DE3706838C2 publication Critical patent/DE3706838C2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE3706838A 1986-03-04 1987-03-03 Neue, physiologisch aktive Substanz, die einen Aldose-Reduktaseinhibitor darstellt, und Verfahren zu ihrer Herstellung Expired - Fee Related DE3706838C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61045327A JPS62205095A (ja) 1986-03-04 1986-03-04 新生理活性物質アルドスタチンおよびその製造法

Publications (2)

Publication Number Publication Date
DE3706838A1 DE3706838A1 (de) 1987-09-10
DE3706838C2 true DE3706838C2 (de) 1995-05-24

Family

ID=12716215

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3706838A Expired - Fee Related DE3706838C2 (de) 1986-03-04 1987-03-03 Neue, physiologisch aktive Substanz, die einen Aldose-Reduktaseinhibitor darstellt, und Verfahren zu ihrer Herstellung

Country Status (5)

Country Link
US (1) US4749571A (ref)
JP (1) JPS62205095A (ref)
DE (1) DE3706838C2 (ref)
FR (1) FR2598085B1 (ref)
GB (1) GB2188047B (ref)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0495049A (ja) * 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd ビフェニル‐５，５’‐ビス‐アルカン酸誘導体、その製造法およびその用途
JPH0495025A (ja) * 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
WO2003043937A2 (en) * 2001-11-15 2003-05-30 Pq Holding, Inc. Method for controlling synthesis conditions during molecular sieve synthesis using combinations of quaternary ammonium hydroxides and halides

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2444762A1 (de) * 1974-09-19 1976-04-08 Merck Patent Gmbh Cephemderivate und verfahren zu ihrer herstellung
CA1157030A (en) * 1977-07-01 1983-11-15 Brian W. Metcalf .alpha.-VINYL AMINO ACIDS
GB2011389B (en) * 1977-12-16 1982-03-10 Degussa Maleic acid semi-amides their production and us
LU78805A1 (de) * 1977-12-30 1979-07-20 Byk Gulden Lomberg Chem Fab Acylhydrocarbylaminoalkansaeuren,ihre herstellung und verwendung sowie sie enthaltende arzneimittel
DE2807286A1 (de) * 1978-02-21 1979-08-23 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten und 4-hydroxyphenylglycinderivaten mit enzymharzen
DE2962385D1 (en) * 1978-06-14 1982-05-06 Byk Gulden Lomberg Chem Fab Substituted amino acids, their use and preparation, and compositions containing them
DE2954076C2 (ref) * 1978-11-25 1988-02-25 Nippon Kayaku K.K., Tokio/Tokyo, Jp
DE3161915D1 (en) * 1980-03-05 1984-02-23 Univ Miami Angiotensin converting enzyme inhibitors
IE51409B1 (en) * 1980-07-24 1986-12-24 Ici Ltd Amide derivatives
EP0047014B1 (en) * 1980-09-02 1986-01-15 Asahi Kasei Kogyo Kabushiki Kaisha Novel thioesters and process for the preparation of the same
DE3037858A1 (de) * 1980-10-07 1982-05-19 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von reaktiven, kupplungsfaehigen derivaten der schilddruesenhormone t (pfeil abwaerts)3(pfeil abwaerts) und t (pfeil abwaerts)4(pfeil abwaerts) und deren verwendung
US4424150A (en) * 1982-04-02 1984-01-03 Syva Company Acetaminophen analogs, antigens, and antibodies
US4551279A (en) * 1984-01-09 1985-11-05 G. D. Searle & Co. Protease inhibitors
JPS60215657A (ja) * 1984-04-10 1985-10-29 Mitsui Toatsu Chem Inc Ｎ−アシルフエニルアラニン類の製造法

Also Published As

Publication number Publication date
GB8704253D0 (en) 1987-04-01
GB2188047A (en) 1987-09-23
US4749571A (en) 1988-06-07
FR2598085A1 (fr) 1987-11-06
DE3706838A1 (de) 1987-09-10
GB2188047B (en) 1989-12-28
JPS62205095A (ja) 1987-09-09
FR2598085B1 (fr) 1988-12-02
JPH0457664B2 (ref) 1992-09-14

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8127 New person/name/address of the applicant

Owner name: ASAHI KASEI KOGYO K.K., OSAKA, JP

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee