DE3486121T2 - 4-((bicyclische heterocyclyl)methyl und -hetero)-piperidine. - Google Patents

4-((bicyclische heterocyclyl)methyl und -hetero)-piperidine.

Info

Publication number
DE3486121T2
DE3486121T2 DE8484201851T DE3486121T DE3486121T2 DE 3486121 T2 DE3486121 T2 DE 3486121T2 DE 8484201851 T DE8484201851 T DE 8484201851T DE 3486121 T DE3486121 T DE 3486121T DE 3486121 T2 DE3486121 T2 DE 3486121T2
Authority
DE
Germany
Prior art keywords
hetero
piperidine
methyl
bicyclic heterocyclyl
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484201851T
Other languages
English (en)
Other versions
DE3486121D1 (en
Inventor
Frans Eduard Janssens
Ludo Edmond Josephine Kennis
Jozef Francis Hens
Joseph Leo G Torremans
Gaston Stanislas M Diels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE3486121D1 publication Critical patent/DE3486121D1/de
Application granted granted Critical
Publication of DE3486121T2 publication Critical patent/DE3486121T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE8484201851T 1984-01-09 1984-12-13 4-((bicyclische heterocyclyl)methyl und -hetero)-piperidine. Expired - Fee Related DE3486121T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56936984A 1984-01-09 1984-01-09
US67113584A 1984-11-13 1984-11-13

Publications (2)

Publication Number Publication Date
DE3486121D1 DE3486121D1 (en) 1993-05-06
DE3486121T2 true DE3486121T2 (de) 1993-07-15

Family

ID=27075046

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484201851T Expired - Fee Related DE3486121T2 (de) 1984-01-09 1984-12-13 4-((bicyclische heterocyclyl)methyl und -hetero)-piperidine.

Country Status (21)

Country Link
EP (1) EP0151826B1 (de)
JP (1) JPH0768240B2 (de)
KR (2) KR870001169B1 (de)
AU (1) AU573673B2 (de)
BG (1) BG40965A3 (de)
CA (1) CA1259609A (de)
DE (1) DE3486121T2 (de)
DK (1) DK8985A (de)
ES (1) ES8706668A1 (de)
FI (1) FI83867C (de)
GR (1) GR850060B (de)
HU (1) HU200338B (de)
IE (1) IE59707B1 (de)
IL (1) IL74018A (de)
MA (1) MA20323A1 (de)
NO (1) NO160849C (de)
NZ (1) NZ210776A (de)
PH (1) PH23995A (de)
PT (1) PT79809B (de)
RO (1) RO90622A (de)
ZW (1) ZW485A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017207340A1 (de) * 2016-05-31 2017-12-07 Bayer Pharma Aktiengesellschaft Neue substituierte benzimidazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln

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US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
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US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
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CA2091204C (en) * 1992-03-11 1997-04-08 Ronald J. Mattson Antiischemic-piperazinyl and piperidinyl-cyclohexanes
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
ATE171447T1 (de) * 1993-03-18 1998-10-15 Merck Sharp & Dohme Benzimidazole derivate
US5521183A (en) * 1994-08-30 1996-05-28 Allergan Use of 5-HT ligands as anti-pruritic agents
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EP1059922A2 (de) * 1998-03-06 2000-12-20 Janssen Pharmaceutica N.V. Hemmer des glycintransports
ATE258928T1 (de) * 1999-06-28 2004-02-15 Janssen Pharmaceutica Nv Respiratorisches syncytialvirus replikation inhibitoren
SK18952001A3 (sk) 1999-06-28 2002-11-06 Janssen Pharmaceutica N. V. Inhibítory replikácie respiračného syncyciálneho vírusu
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US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017207340A1 (de) * 2016-05-31 2017-12-07 Bayer Pharma Aktiengesellschaft Neue substituierte benzimidazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
FI83867C (fi) 1991-09-10
DK8985A (da) 1985-07-10
GR850060B (de) 1985-04-05
KR900001545B1 (ko) 1990-03-12
ZW485A1 (en) 1986-07-30
NO850085L (no) 1985-07-10
PH23995A (en) 1990-02-09
IE59707B1 (en) 1994-03-23
ES8706668A1 (es) 1987-06-16
PT79809A (en) 1985-02-01
FI850079L (fi) 1985-07-10
NO160849B (no) 1989-02-27
KR880013431A (ko) 1988-11-30
IE850042L (en) 1985-07-09
EP0151826A1 (de) 1985-08-21
DE3486121D1 (en) 1993-05-06
BG40965A3 (en) 1987-03-14
CA1259609A (en) 1989-09-19
NO160849C (no) 1989-06-07
FI850079A0 (fi) 1985-01-08
HUT36471A (en) 1985-09-30
HU200338B (en) 1990-05-28
AU3736485A (en) 1985-09-12
KR870001169B1 (ko) 1987-06-15
AU573673B2 (en) 1988-06-16
PT79809B (en) 1987-01-07
EP0151826B1 (de) 1993-03-31
RO90622A (ro) 1986-12-10
KR850005436A (ko) 1985-08-26
FI83867B (fi) 1991-05-31
IL74018A (en) 1988-08-31
DK8985D0 (da) 1985-01-08
MA20323A1 (fr) 1985-10-01
NZ210776A (en) 1988-03-30
JPH0768240B2 (ja) 1995-07-26
JPS60185777A (ja) 1985-09-21
ES539281A0 (es) 1987-06-16

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