BG40965A3 - Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines - Google Patents

Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines

Info

Publication number
BG40965A3
BG40965A3 BG8568329A BG6832985A BG40965A3 BG 40965 A3 BG40965 A3 BG 40965A3 BG 8568329 A BG8568329 A BG 8568329A BG 6832985 A BG6832985 A BG 6832985A BG 40965 A3 BG40965 A3 BG 40965A3
Authority
BG
Bulgaria
Prior art keywords
piperidines
hetero
methyl
preparing
bicyclic heterocyclic
Prior art date
Application number
BG8568329A
Other languages
English (en)
Inventor
Janssens
Josephinekennis
Hens
Ghisianustorremans
Marcelladiels
Original Assignee
Janssen Pharmaceutica Nv,Be
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv,Be filed Critical Janssen Pharmaceutica Nv,Be
Publication of BG40965A3 publication Critical patent/BG40965A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG8568329A 1984-01-09 1985-01-09 Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines BG40965A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56936984A 1984-01-09 1984-01-09
US67113584A 1984-11-13 1984-11-13

Publications (1)

Publication Number Publication Date
BG40965A3 true BG40965A3 (en) 1987-03-14

Family

ID=27075046

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8568329A BG40965A3 (en) 1984-01-09 1985-01-09 Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines

Country Status (21)

Country Link
EP (1) EP0151826B1 (xx)
JP (1) JPH0768240B2 (xx)
KR (2) KR870001169B1 (xx)
AU (1) AU573673B2 (xx)
BG (1) BG40965A3 (xx)
CA (1) CA1259609A (xx)
DE (1) DE3486121T2 (xx)
DK (1) DK8985A (xx)
ES (1) ES8706668A1 (xx)
FI (1) FI83867C (xx)
GR (1) GR850060B (xx)
HU (1) HU200338B (xx)
IE (1) IE59707B1 (xx)
IL (1) IL74018A (xx)
MA (1) MA20323A1 (xx)
NO (1) NO160849C (xx)
NZ (1) NZ210776A (xx)
PH (1) PH23995A (xx)
PT (1) PT79809B (xx)
RO (1) RO90622A (xx)
ZW (1) ZW485A1 (xx)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0144101B1 (en) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8515934D0 (en) * 1985-06-24 1985-07-24 Janssen Pharmaceutica Nv (4-piperidinomethyl and-hetero)purines
FR2587029B1 (fr) * 1985-09-11 1987-10-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
ES2052544T3 (es) * 1986-02-03 1994-07-16 Janssen Pharmaceutica Nv Composiciones anti-histaminicas que contienen n-heterociclil-4-piperidinaminas.
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4943580A (en) * 1987-03-09 1990-07-24 Janssen Pharmaceutica N.V. Anti-histaminic benzimidazole, imidazopyridine and purine derivatives
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
IT1229230B (it) * 1989-05-08 1991-07-26 Dompe Farmaceutici Spa Piperidinilimidazopiridine farmacologicamente attive.
US5200407A (en) * 1989-06-29 1993-04-06 Meiji Seika Kaburhiki Kaisha Azole derivatives and anti-ulcerative composition containing same
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
CA2022451C (en) * 1989-08-03 2001-01-23 Albert Anthony Carr Anti-psychotic piperidynl benzimidazole compounds
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds
KR100190299B1 (ko) * 1990-07-19 1999-06-01 디르크 반테 신규한 옥사졸릴 유도체
WO1992006086A1 (en) * 1990-10-01 1992-04-16 Janssen Pharmaceutica N.V. Novel 4-piperidinylcarbonyl derivatives
CA2097317C (en) * 1990-12-14 2002-02-12 Albert A. Carr Antiallergic piperdinyl benzimidazoles
WO1993014083A1 (en) * 1992-01-09 1993-07-22 Janssen Pharmaceutica N.V. Pharmaceutically active substituted benzimidazole derivatives
AU669156B2 (en) * 1992-02-13 1996-05-30 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
CA2091204C (en) * 1992-03-11 1997-04-08 Ronald J. Mattson Antiischemic-piperazinyl and piperidinyl-cyclohexanes
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
ATE171447T1 (de) * 1993-03-18 1998-10-15 Merck Sharp & Dohme Benzimidazole derivate
US5521183A (en) * 1994-08-30 1996-05-28 Allergan Use of 5-HT ligands as anti-pruritic agents
TW429256B (en) * 1995-12-27 2001-04-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives
EP1059922A2 (en) * 1998-03-06 2000-12-20 Janssen Pharmaceutica N.V. Glycine transport inhibitors
ATE258928T1 (de) * 1999-06-28 2004-02-15 Janssen Pharmaceutica Nv Respiratorisches syncytialvirus replikation inhibitoren
SK18952001A3 (sk) 1999-06-28 2002-11-06 Janssen Pharmaceutica N. V. Inhibítory replikácie respiračného syncyciálneho vírusu
SG122814A1 (en) 1999-06-28 2006-06-29 Janssen Pharmaceutica Nv Respiratory syncytial virus replication inhibitors
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
AR033517A1 (es) * 2000-04-08 2003-12-26 Astrazeneca Ab Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos
SK288003B6 (sk) * 2001-02-24 2012-10-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthin derivatives, method for the preparation thereof, pharmaceutical composition containing thereof and their use
US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
DE60209736T2 (de) 2001-07-02 2006-11-02 Astrazeneca Ab Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen
US6530660B1 (en) 2001-08-16 2003-03-11 Contour Optik, Inc. Eyeglass frame with a reversible arm
GB0120461D0 (en) 2001-08-22 2001-10-17 Astrazeneca Ab Novel compounds
GB0122503D0 (en) 2001-09-18 2001-11-07 Astrazeneca Ab Chemical compounds
JP2005532991A (ja) * 2002-01-10 2005-11-04 ニューロジェン・コーポレーション メラニン凝集ホルモン受容体リガンド：置換２−（４−ベンジル−ピペラジン−１−イルメチル）−及び２−（４−ベンジル−ジアゼパン−１−イルメチル）−１ｈ−ベンゾイミダゾールアナログ
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
US6939877B2 (en) 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
US7026321B2 (en) * 2003-01-17 2006-04-11 Cv Therapeutics, Inc. Substituted heterocyclic compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
KR100640783B1 (ko) 2004-10-30 2006-11-01 주식회사 하이닉스반도체 노이즈를 줄일 수 있는 데이터 출력 드라이버
ATE478075T1 (de) 2005-03-08 2010-09-15 Janssen Pharmaceutica Nv Diazaspiro-ä4,4ü-nonanderivate als neurokinin- (nk1)-antagonisten
EP2402316A1 (en) 2005-07-21 2012-01-04 AstraZeneca AB (Publ) Piperidine derivatives
ES2369320T3 (es) * 2007-10-11 2011-11-29 Glaxo Group Limited Compuestos de ftalazina y pirido(3,4-d)piridazina como antagonistas del receptor h1.
JP5650329B2 (ja) 2010-09-02 2015-01-07 スヴェン ライフ サイエンシズ リミテッド ヒスタミンｈ３受容体リガンドとしてのヘテロシクリル化合物
US10913736B2 (en) * 2014-08-22 2021-02-09 University Of Washington Specific inhibitors of methionyl-tRNA synthetase
RU2766579C2 (ru) 2015-07-02 2022-03-15 ХОРАЙЗОН ОРФАН ЭлЭлСи Цистеаминдиоксигеназа-резистентные аналоги цистеамина и их применение
WO2017207340A1 (de) * 2016-05-31 2017-12-07 Bayer Pharma Aktiengesellschaft Neue substituierte benzimidazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2857391A (en) * 1955-04-15 1958-10-21 Merck & Co Inc Aminomethylbenzimidazoles
GB1260857A (en) * 1968-07-10 1972-01-19 Hexachimie IMIDAZO-3H-(4,5-b)-PYRIDINE DERIVATIVES
DE2334009A1 (de) * 1973-07-04 1975-01-23 Boehringer Mannheim Gmbh Purin-derivate sowie verfahren zu ihrer herstellung
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
PL129375B1 (en) * 1980-07-24 1984-05-31 Rhone Poulenc Ind Process for preparing novel derivatives of 2,3,6,7-tetrahydro-thiazole-/3,2-a/-pyrimidin-5-one
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
EP0144101B1 (en) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives

Also Published As

Publication number Publication date
FI83867C (fi) 1991-09-10
DK8985A (da) 1985-07-10
GR850060B (xx) 1985-04-05
KR900001545B1 (ko) 1990-03-12
ZW485A1 (en) 1986-07-30
NO850085L (no) 1985-07-10
PH23995A (en) 1990-02-09
IE59707B1 (en) 1994-03-23
ES8706668A1 (es) 1987-06-16
PT79809A (en) 1985-02-01
FI850079L (fi) 1985-07-10
NO160849B (no) 1989-02-27
KR880013431A (ko) 1988-11-30
IE850042L (en) 1985-07-09
EP0151826A1 (en) 1985-08-21
DE3486121D1 (en) 1993-05-06
DE3486121T2 (de) 1993-07-15
CA1259609A (en) 1989-09-19
NO160849C (no) 1989-06-07
FI850079A0 (fi) 1985-01-08
HUT36471A (en) 1985-09-30
HU200338B (en) 1990-05-28
AU3736485A (en) 1985-09-12
KR870001169B1 (ko) 1987-06-15
AU573673B2 (en) 1988-06-16
PT79809B (en) 1987-01-07
EP0151826B1 (en) 1993-03-31
RO90622A (ro) 1986-12-10
KR850005436A (ko) 1985-08-26
FI83867B (fi) 1991-05-31
IL74018A (en) 1988-08-31
DK8985D0 (da) 1985-01-08
MA20323A1 (fr) 1985-10-01
NZ210776A (en) 1988-03-30
JPH0768240B2 (ja) 1995-07-26
JPS60185777A (ja) 1985-09-21
ES539281A0 (es) 1987-06-16

Similar Documents

Publication Publication Date Title
BG40965A3 (en) Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines
PT81000A (en) Process for the preparation of heterocyclic derivatives
YU43977B (en) Process for obtaining new 2-(n-substituted-guanidine)-4-heteroarylthiazole
PL265151A1 (en) Method for manufacturing new heterocyclic carboxyamides
BG44204A3 (en) Method for preparing of 2- oxyindol derivatives
BG45698A3 (en) Method for preparing of dimethyltherephthalate
PL279344A1 (en) Method for manufacturing new heterocyclic compounds
PL252743A1 (en) Method of obtaining heterocyclic compounds
GR82451B (en) Method of preparing heterocyclic compounds
PT81510A (en) Process for preparing v1-vasopressin antagonists
BG44203A3 (en) Method for preparing of 2- oxyindol- 1- carboxamides
HUT37613A (en) Process for preparing imidazole derivatives
HU9201172D0 (en) Method for producing 5-substituted hydantoin derivatives
GR860718B (en) Method for the preparation of heterocyclic compounds
PT80327B (en) Process for preparing 3-substituted thiopyrones
GR861806B (en) Method for the preparation of heterocyclic compounds
GR861906B (en) Method for preparing heterocyclic compounds
BG39193A1 (en) Method for preparing 2- [(n- 2- pyridylcarbamoyl)- methyl]- saccharin
BG38699A1 (en) Method for preparing triacetonamine
PL255306A1 (en) Method of obtaining novel heterocyclic compounds
PL245781A1 (en) Method of obtaining novel heterocyclic compounds
PL251480A1 (en) Method of obtaining novel heterocyclic compounds
BG42834A3 (en) Method for preparing azole compounds
GR860095B (en) Method for the preparation of novel heterocyclic compounds
GR80572B (en) Method for the preparation of heterocyclic compounds